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1. Full Text Preparation of Both C5′ Epimers of 5′‑C‑Methyladenosine: Reagent Control Trumps Substrate Control
by Bligh, Cavan M and Anzalone, Luigi and Jung, Young Chun and Zhang, Yuegang and Nugent, William A
The Journal of Organic Chemistry, ISSN 0022-3263, 04/2014, Volume 79, Issue 7, pp. 3238 - 3243
Adenosine-derived ketone 5 was subjected to Noyori asymmetric transfer hydrogenation (ATH) using aqueous sodium formate as a stoichiometric reductant. Despite... 
LIGAND BIFUNCTIONAL CATALYSIS | POTENTIAL ANTICANCER AGENTS | ASYMMETRIC TRANSFER HYDROGENATION | TARTARIC ACID | ADENOSINE-DEAMINASE | AROMATIC KETONES | REDUCTION | NUCLEOSIDES | COMPLEXES | CHEMISTRY, ORGANIC | CARBONYL-COMPOUNDS | Ketones - chemical synthesis | Stereoisomerism | Adenosine - analogs & derivatives | Ketones - chemistry | Adenosine - chemistry | Catalysis | Deoxyguanosine - chemistry | Indicators and Reagents - chemistry | Adenosine | Research | Chemical properties | Ketones | Hydrogenation
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2. Full Text Osteocyte control of osteoclastogenesis
by O'Brien, Charles A and Nakashima, Tomoki and Takayanagi, Hiroshi
Bone, ISSN 8756-3282, 2012, Volume 54, Issue 2, pp. 258 - 263
Abstract Multiple lines of evidence support the idea that osteocytes act as mechanosensors in bone and that they control bone formation, in part, by expressing... 
Orthopedics | Resorption | RANKL | Osteoclast | Osteocyte | Apoptosis | RHEUMATOID-ARTHRITIS | DISTANT TRANSCRIPTIONAL ENHANCER | DIFFERENTIATION FACTOR | BONE-RESORPTION | LYMPH-NODE ORGANOGENESIS | ESTROGEN-RECEPTOR-ALPHA | ENDOCRINOLOGY & METABOLISM | PARATHYROID-HORMONE | 1,25-DIHYDROXYVITAMIN D-3 | VAN-BUCHEM-DISEASE | KAPPA-B LIGAND | Animals | RANK Ligand - metabolism | Osteocytes - metabolism | Signal Transduction | Humans | Osteocytes - cytology | Cell Differentiation | Osteoclasts - cytology | Osteoclasts - metabolism | Osteogenesis | resorption | apoptosis | osteocyte | osteoclast
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3. Full Text Molecular control of δ-opioid receptor signalling
by Fenalti, Gustavo and Giguere, Patrick M and Katritch, Vsevolod and Huang, Xi-Ping and Thompson, Aaron A and Cherezov, Vadim and Roth, Bryan L and Stevens, Raymond C
Nature, ISSN 0028-0836, 2014, Volume 506, Issue 7487, pp. 191 - 196
Opioids represent widely prescribed and abused medications, although their signal transduction mechanisms are not well understood. Here we present the 1.8... 
CRYSTALLIZING MEMBRANE | ALLOSTERIC REGULATION | INVERSE AGONISTS | SODIUM | DESIGN | PROTEIN | MULTIDISCIPLINARY SCIENCES | ANTAGONISTS | BINDING | SELECTIVITY | DISCOVERY | Naltrexone - analogs & derivatives | Receptors, Opioid, delta - metabolism | Humans | Naltrexone - chemistry | Crystallography, X-Ray | Structure-Activity Relationship | Sodium - metabolism | Arrestins - metabolism | Narcotic Antagonists - chemistry | Naltrexone - pharmacology | Narcotic Antagonists - metabolism | Receptors, Opioid, delta - genetics | Receptors, Opioid, delta - antagonists & inhibitors | Asparagine - genetics | Naltrexone - metabolism | Allosteric Regulation - drug effects | Allosteric Site - genetics | Sodium - pharmacology | Allosteric Regulation - genetics | Mutagenesis, Site-Directed | Receptors, Opioid, delta - chemistry | Allosteric Site - drug effects | Models, Molecular | Signal Transduction - drug effects | beta-Arrestins | Asparagine - metabolism | Narcotic Antagonists - pharmacology | Ligands | Receptors, Opioid, delta - agonists | Index Medicus | sodium regulation | constitutive activity | human opioid receptor | arrestin | functional selectivity | GPCR signaling | allostery
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4. Full Text Control of the T Follicular Helper–Germinal Center B-Cell Axis by CD8+ Regulatory T Cells Limits Atherosclerosis and Tertiary Lymphoid Organ Development
by Clement, Marc and Guedj, Kevin and Andreata, Francesco and Morvan, Marion and Bey, Laetitia and Khallou-Laschet, Jamila and Gaston, Anh-Thu and Delbosc, Sandrine and Alsac, Jean-Marc and Bruneval, Patrick and Deschildre, Catherine and Le Borgne, Marie and Castier, Yves and Kim, Hye-Jung and Cantor, Harvey and Michel, Jean-Baptiste and Caligiuri, Giuseppina and Nicoletti, Antonino
Circulation, ISSN 0009-7322, 02/2015, Volume 131, Issue 6, pp. 560 - 570
BACKGROUND—The atheromodulating activity of B cells during the development of atherosclerosis is well documented, but the mechanisms by which these cells are... 
atherosclerosis | inflammation | leukocytes | ACTIVATION | CARDIAC & CARDIOVASCULAR SYSTEMS | NEOGENESIS | TOLERANCE | RECEPTOR | E KNOCKOUT MICE | REDUCES ATHEROSCLEROSIS | RESPONSES | DISEASE | PERIPHERAL VASCULAR DISEASE | GENERATION | CHRONIC REJECTION | Inducible T-Cell Co-Stimulator Ligand - immunology | Atherosclerosis - immunology | Germinal Center - immunology | Humans | Adventitia - immunology | Mice, Knockout | Animals | B-Lymphocytes - immunology | Inducible T-Cell Co-Stimulator Ligand - metabolism | T-Lymphocytes, Regulatory | Female | Adventitia - pathology | Mice | CD8-Positive T-Lymphocytes - immunology | In Vitro Techniques | Flow cytometry | Usage | Care and treatment | Atherosclerosis | Physiological aspects | Fluorescent antibody technique | Research | Leukocytes | Immunofluorescence | T cells | Risk factors
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5. Full Text Matrix-embedded cells control osteoclast formation
by Xiong, Jinhu and Onal, Melda and Jilka, Robert L and Weinstein, Robert S and Manolagas, Stavros C and O'Brien, Charles A
Nature Medicine, ISSN 1078-8956, 10/2011, Volume 17, Issue 10, pp. 1235 - 1241
Osteoclasts resorb the mineralized matrices formed by chondrocytes or osteoblasts. The cytokine receptor activator of nuclear factor-kappa B ligand (RANKL) is... 
MEDICINE, RESEARCH & EXPERIMENTAL | OSTEOCYTES | RANKL | BIOCHEMISTRY & MOLECULAR BIOLOGY | CRE RECOMBINASE | BONE-RESORPTION | OSTEOBLASTIC CELLS | CELL BIOLOGY | OSTEOPROTEGERIN LIGAND | RECEPTOR ACTIVATOR | DIFFERENTIATION | EXPRESSION | KAPPA-B LIGAND | RANK Ligand - metabolism | Mice, Transgenic | Bone Remodeling - physiology | Bone Matrix - cytology | Osteoclasts - cytology | Radiography | Bone Matrix - physiology | Animals | Analysis of Variance | Histological Techniques | Bone and Bones - diagnostic imaging | Bone and Bones - metabolism | Polymerase Chain Reaction | Bone Resorption - metabolism | Mice | Osteoblasts - metabolism | Chondrocytes - metabolism | Transcription factors | Cytokines | Physiological aspects | Genetic aspects | Research | Cell differentiation | Osteoblasts | Bones | Skeletal system | Matrix | Biomedical research | Cellular biology
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6. Full Text Remote control of neuronal signaling
by Rogan, Sarah C and Roth, Bryan L
Pharmacological Reviews, ISSN 0031-6997, 06/2011, Volume 63, Issue 2, pp. 291 - 315
A significant challenge for neuroscientists is to determine how both electrical and chemical signals affect the activity of cells and circuits and how the... 
ACTIVATION BINDING-SITES | IN-VIVO CONTROL | BETA-ADRENERGIC-RECEPTOR | SYNTHETIC LIGANDS RASSL | CLOZAPINE-N-OXIDE | PROTEIN-COUPLED RECEPTORS | PHARMACOLOGY & PHARMACY | DESIGNED G(I)-COUPLED RECEPTOR | IONOTROPIC GLUTAMATE-RECEPTOR | GATED SODIUM-CHANNEL | MUSCARINIC ACETYLCHOLINE-RECEPTORS | Animals | Peptides - metabolism | Receptors, G-Protein-Coupled - metabolism | Signal Transduction | Designer Drugs - metabolism | Humans | Light | Opsins - metabolism | Ligands | Neurons - metabolism | Receptors, G-Protein-Coupled - drug effects | Review
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7. Full Text Full Selectivity Control in Cobalt(III)‐Catalyzed C−H Alkylations by Switching of the C−H Activation Mechanism
by Zell, Daniel and Bursch, Markus and Müller, Valentin and Grimme, Stefan and Ackermann, Lutz
Angewandte Chemie International Edition, ISSN 1433-7851, 08/2017, Volume 56, Issue 35, pp. 10378 - 10382
Selectivity control in hydroarylation‐based C−H alkylation has been dominated by steric interactions. A conceptually distinct strategy that exploits the... 
selectivity | cobalt | C−H activation | hydroarylation | reaction mechanism | COVALENT ATTACHMENT | PERFORMANCE | PORPHYRINS | COMPLEXES | CHEMISTRY, MULTIDISCIPLINARY | ORGANIC ELECTRODE MATERIALS | CAPACITIVE ENERGY-STORAGE | C-H activation | POLYMER | FRAMEWORK | DEVICES | RECHARGEABLE LITHIUM BATTERIES | Cobalt | Network switches | Catalysis | Alkenes | Ligands | Activation | Selectivity | Alkylation | Switching
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8. Full Text Toll-like receptors control autophagy
by Davis, Alexander S and Elmaoued, Rasha A and Deretic, Vojo and Kyei, George and Delgado, Mónica A
The EMBO Journal, ISSN 0261-4189, 04/2008, Volume 27, Issue 7, pp. 1110 - 1121
Autophagy is a newly recognized innate defense mechanism, acting as a cell‐autonomous system for elimination of intracellular pathogens. The signals and... 
autophagy | TLR | HIV | LC3 | tuberculosis | Tuberculosis | Autophagy | MYCOBACTERIUM-TUBERCULOSIS | KINASE-ACTIVITY | NADPH OXIDASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | DEFENSE-MECHANISM | CUTTING EDGE | CELL BIOLOGY | PLASMACYTOID DENDRITIC CELLS | ADAPTIVE IMMUNITY | CROSS-TALK | TOXOPLASMA-GONDII | MATURATION STEP | Macrophages - ultrastructure | Toll-Like Receptor 7 - metabolism | Microtubule-Associated Proteins - metabolism | Humans | Mice, Inbred C57BL | Immunoblotting | Autophagy - physiology | Macrophages - cytology | Animals | Intracellular Space - microbiology | Mycobacterium tuberculosis | Ligands | Mice | Protein Processing, Post-Translational | HeLa Cells | Toll-Like Receptors - metabolism | Myeloid Differentiation Factor 88 - metabolism | Cytoplasmic Structures - metabolism | RNA, Small Interfering - metabolism | Pathogens | Signal transduction | Immunology | Cellular biology
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9. Full Text 50‐Fold EQE Improvement up to 6.27% of Solution‐Processed All‐Inorganic Perovskite CsPbBr3 QLEDs via Surface Ligand Density Control
by Li, Jianhai and Xu, Leimeng and Wang, Tao and Song, Jizhong and Chen, Jiawei and Xue, Jie and Dong, Yuhui and Cai, Bo and Shan, Qingsong and Han, Boning and Zeng, Haibo
Advanced Materials, ISSN 0935-9648, 02/2017, Volume 29, Issue 5, p. n/a
Solution‐processed CsPbBr3 quantum‐dot light‐emitting diodes with a 50‐fold external quantum efficiency improvement (up to 6.27%) are achieved through... 
cesium lead halides (CsPbX3) | surface ligand density control | colloidal nanocrystals | all‐inorganic perovskites | quantum‐dot light‐emitting diodes (QLEDs) | cesium lead halides (CsPbX | quantum-dot light-emitting diodes (QLEDs) | all-inorganic perovskites | PHYSICS, CONDENSED MATTER | PHYSICS, APPLIED | MATERIALS SCIENCE, MULTIDISCIPLINARY | NANOCRYSTALS | CHEMISTRY, PHYSICAL | NANOSCIENCE & NANOTECHNOLOGY | CHEMISTRY, MULTIDISCIPLINARY | ELECTROLUMINESCENCE | QUANTUM DOTS | LIGHT-EMITTING-DIODES | TRANSPORT | LUMINESCENCE | CSPBX3 | CESIUM LEAD HALIDE | HIGH-EFFICIENCY | Light-emitting diodes | Perovskite | Thin films | Quantum efficiency | Quantum dots | Photoluminescence | Organic light emitting diodes | Carrier injection | Light emitting diodes | Ligands | Ethyl acetate | Passivity | Carrier density
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10. Full Text Control of Immunity by the TNFR-related molecule OX40 (CD134)
by Croft, Michael
Annual Review of Immunology, ISSN 0732-0582, 04/2010, Volume 28, Issue 1, pp. 57 - 78
TNFR/TNF superfamily members can control diverse aspects of immune function. Research over the past 10 years has shown that one of the most important and... 
Autoimmunity | Infectious disease | T cells | Costimulation | OX40L | Vaccination | OX40-OX40 LIGAND INTERACTION | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | PLASMACYTOID-DENDRITIC-CELLS | HUMAN NK CELLS | IMMUNOLOGY | GROWTH-FACTOR RECEPTOR | TUMOR-NECROSIS-FACTOR | T-CELL RESPONSES | IL-1 RECEPTOR ANTAGONIST | costimulation | autoimmunity | infectious disease | IN-VIVO | VASCULAR ENDOTHELIAL-CELLS | vaccination | Receptors, OX40 - metabolism | Animals | OX40 Ligand - immunology | Signal Transduction | T-Lymphocytes - metabolism | OX40 Ligand - metabolism | Humans | Cell Communication | Killer Cells, Natural - immunology | T-Lymphocytes - immunology | Killer Cells, Natural - metabolism | Receptors, OX40 - immunology | Care and treatment | Physiological aspects | Antigen presenting cells | Research | Properties | Identification and classification | Immune system | Cancer | Immunological research
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