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by Meng, S and Zhang, L and Tang, Y and Tu, Q and Zheng, L and Yu, L and Murray, D and Cheng, J and Kim, S.H and Zhou, X and Chen, J
Journal of dental research, ISSN 1544-0591, 05/2014, Volume 93, Issue 7, pp. 657 - 662
...) inhibitor, JQ1, was proved to suppress oncogene transcription and inflammatory responses. The present study was aimed to investigate the effects of JQ1 on inflammatory response and bone destruction in experimental periodontitis... 
Epigenetics | Osteoclasts | BRD4 protein | Experimental animal models | Periodontitis | Anti-inflammatory agents | Life Sciences & Biomedicine | Dentistry, Oral Surgery & Medicine | Science & Technology | Interleukin-1beta - drug effects | Transcription Factor AP-1 - drug effects | Toll-Like Receptor 2 - antagonists & inhibitors | Alveolar Bone Loss - prevention & control | Cathepsin K - drug effects | Tartrate-Resistant Acid Phosphatase | Promoter Regions, Genetic - drug effects | Lipopolysaccharides - adverse effects | RANK Ligand - drug effects | Proto-Oncogene Proteins c-ets - drug effects | Cell Differentiation | Toll-Like Receptor 4 - antagonists & inhibitors | Acid Phosphatase - drug effects | Transcription Factors - therapeutic use | Cell Line | Proto-Oncogene Proteins c-fos - drug effects | Nuclear Proteins - therapeutic use | Periodontitis - prevention & control | NFATC Transcription Factors - drug effects | Animals | Tumor Necrosis Factor-alpha - drug effects | Isoenzymes - drug effects | Mice | Osteoclasts - drug effects | NF-kappa B - drug effects | Phosphorylation | Chromatin | Immunoprecipitation | Disease | Transcription | Laboratories | Calcineurin | Inflammatory diseases | Lipopolysaccharides | Interleukin 6 | Proteins | Toll-like receptors | Bacteria | Tumor necrosis factor-TNF | TRANCE protein | Bone loss | c-Fos protein | NF-κB protein | Medical research | Cathepsin K | Cytokines | Therapeutic applications | Alveolar bone | Inflammation | RNA polymerase | Tumor necrosis factor-α | Gene expression | Nuclear transport | Polymerase chain reaction | Lymphocytes B | TLR2 protein | Acid phosphatase (tartrate-resistant) | Index Medicus | Dentistry | experimental animal models | periodontitis | osteoclasts | anti-inflammatory agents | Research Reports | epigenetics
Journal Article
Nature (London), ISSN 1476-4687, 08/2016, Volume 537, Issue 7619, pp. 185 - 190
Journal Article
Angewandte Chemie (International ed.), ISSN 1521-3773, 01/2009, Volume 48, Issue 3, pp. 456 - 494
Journal Article
PloS one, ISSN 1932-6203, 01/2011, Volume 6, Issue 1, pp. e16270 - e16270
Journal Article
PloS one, ISSN 1932-6203, 10/2011, Volume 6, Issue 10, pp. e25900 - e25900
...) and measured effects on pro-catabolic gene expression. Sclerostin dose-dependently up-regulated the expression of receptor activator of nuclear factor kappa B (RANKL... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Osteocytes - drug effects | RANK Ligand - metabolism | Apoptosis - drug effects | Humans | Tartrate-Resistant Acid Phosphatase | Osteoclasts - cytology | Cell Differentiation - genetics | Acid Phosphatase - metabolism | Isoenzymes - metabolism | Adult | Osteoblasts - cytology | Bone Morphogenetic Proteins - pharmacology | Osteogenesis - genetics | Cell Survival - drug effects | Calcification, Physiologic - drug effects | Osteocytes - metabolism | Osteoblasts - drug effects | Osteocytes - cytology | Osteogenesis - drug effects | Cells, Cultured | Genetic Markers | Recombinant Proteins - pharmacology | Osteoclasts - metabolism | Gene Expression Regulation - drug effects | RANK Ligand - genetics | Animals | Signal Transduction - drug effects | Cell Differentiation - drug effects | Mice | Osteoblasts - metabolism | Osteoclasts - drug effects | Bones | RNA | Gene expression | Density | Genes | Homeostasis | Osteocytes | Leukocytes (mononuclear) | SOST protein | Biology | Kinases | Osteoprotegerin | Monoculture | Ethics | Genotype & phenotype | Splenocytes | Peripheral blood mononuclear cells | Tumor necrosis factor-TNF | Biocompatibility | TRANCE protein | Discipline | Cytokines | Caspase | Bone mass | Osteoblastogenesis | Low density lipoprotein receptors | Osteoclasts | Acid phosphatase (tartrate-resistant) | Apoptosis | Index Medicus
Journal Article
Stem cells (Dayton, Ohio), ISSN 1066-5099, 12/2010, Volume 28, Issue 12, pp. 2217 - 2228
Journal Article