X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (7687) 7687
Book Review (840) 840
Publication (837) 837
Book Chapter (102) 102
Conference Proceeding (51) 51
Dissertation (40) 40
Magazine Article (4) 4
Book / eBook (3) 3
Newspaper Article (3) 3
Trade Publication Article (1) 1
Web Resource (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
lipogenesis (5507) 5507
index medicus (5300) 5300
animals (3993) 3993
humans (2481) 2481
male (2324) 2324
mice (2019) 2019
metabolism (1957) 1957
liver (1743) 1743
liver - metabolism (1630) 1630
fatty acids (1564) 1564
lipids (1551) 1551
lipid metabolism (1533) 1533
obesity (1472) 1472
biochemistry & molecular biology (1461) 1461
rats (1336) 1336
gene expression (1204) 1204
female (1191) 1191
insulin (1116) 1116
physiological aspects (1112) 1112
glucose (1039) 1039
insulin-resistance (1034) 1034
nutrition & dietetics (962) 962
lipogenesis - drug effects (941) 941
insulin resistance (938) 938
endocrinology & metabolism (914) 914
diet (878) 878
adipose-tissue (831) 831
gene-expression (830) 830
expression (821) 821
rodents (785) 785
research (767) 767
cell biology (745) 745
proteins (739) 739
fatty liver (731) 731
mice, inbred c57bl (720) 720
triglycerides (712) 712
adipose tissue (708) 708
de-novo lipogenesis (705) 705
lipolysis (695) 695
cholesterol (689) 689
lipogenesis - genetics (684) 684
adipose tissue - metabolism (646) 646
fatty acids - metabolism (609) 609
liver - drug effects (597) 597
enzymes (583) 583
adipocytes (573) 573
physiology (561) 561
glucose - metabolism (560) 560
article (547) 547
liver diseases (543) 543
triglycerides - metabolism (535) 535
analysis (531) 531
lipid-metabolism (509) 509
adipogenesis (508) 508
diabetes (508) 508
genes (504) 504
multidisciplinary sciences (500) 500
inflammation (496) 496
steatosis (492) 492
metabolic syndrome (489) 489
obesity - metabolism (478) 478
synthesis (478) 478
signal transduction (477) 477
hepatic steatosis (472) 472
body weight (460) 460
activation (453) 453
oxidation (450) 450
old medline (447) 447
cells, cultured (433) 433
homeostasis (431) 431
lipogenesis - physiology (413) 413
sterol regulatory element binding protein 1 - metabolism (402) 402
adipocytes - metabolism (398) 398
fatty-acid synthase (398) 398
health aspects (396) 396
lipid metabolism - drug effects (394) 394
oxidative stress (394) 394
cells (388) 388
adipose tissues (387) 387
research article (380) 380
phosphorylation (378) 378
agriculture, dairy & animal science (377) 377
gene expression regulation (376) 376
rna, messenger - metabolism (375) 375
food science & technology (373) 373
medicine (371) 371
adult (369) 369
cancer (369) 369
fatty liver-disease (357) 357
nutrition (356) 356
protein binding (354) 354
glucose metabolism (346) 346
growth (345) 345
pharmacology & pharmacy (345) 345
triglycerides - blood (345) 345
liver - pathology (344) 344
fatty liver - metabolism (343) 343
dextrose (342) 342
lipids - biosynthesis (337) 337
kinases (335) 335
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (7604) 7604
French (59) 59
German (35) 35
Korean (29) 29
Chinese (21) 21
Italian (21) 21
Japanese (20) 20
Spanish (16) 16
Portuguese (15) 15
Polish (9) 9
Russian (7) 7
Hungarian (5) 5
Czech (2) 2
Dutch (1) 1
Swedish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2013, Volume 110, Issue 22, pp. 8882 - 8887
Journal Article
Toxicon, ISSN 0041-0101, 12/2018, Volume 156, p. S119
Journal Article
Hepatology, ISSN 0270-9139, 06/2011, Volume 53, Issue 6, pp. 1895 - 1905
Drug‐induced liver injury occurs in general after several weeks and is often unpredictable. It is characterized by a large spectrum of lesions that includes... 
MITOCHONDRIAL BETA-OXIDATION | MICROVESICULAR STEATOSIS | IN-VITRO | DRUG-INDUCED PHOSPHOLIPIDOSIS | LIPID-METABOLISM | EXPRESSION ANALYSIS | HUMAN HEPATOCYTES | CYTOCHROMES P450 | FATTY LIVER-DISEASE | HEPATOTOXICITY | GASTROENTEROLOGY & HEPATOLOGY | Fatty Acid Synthase, Type I - genetics | Fatty Liver - pathology | Humans | Fatty Liver - chemically induced | Phosphoproteins - metabolism | Amiodarone - adverse effects | Oleic Acid - pharmacology | Lipogenesis - genetics | Up-Regulation - physiology | Lipid Metabolism - genetics | Liver Neoplasms - pathology | Membrane Proteins - metabolism | Lipogenesis - physiology | Amiodarone - pharmacology | Carrier Proteins | Fatty Liver - metabolism | Membrane Proteins - genetics | Tetracycline - pharmacology | Up-Regulation - genetics | Tetracycline - adverse effects | Phosphoproteins - genetics | Down-Regulation - drug effects | Fatty Acid Synthase, Type I - metabolism | Stearoyl-CoA Desaturase - genetics | Down-Regulation - genetics | Triglycerides - metabolism | Down-Regulation - physiology | Up-Regulation - drug effects | Lipogenesis - drug effects | Carcinoma, Hepatocellular - pathology | Lipid Metabolism - drug effects | Liver Neoplasms - metabolism | Cell Line, Tumor | Stearoyl-CoA Desaturase - metabolism | Perilipin-4 | Lipid Metabolism - physiology | Perilipin-2 | Carcinoma, Hepatocellular - metabolism | Drugs | Fatty acids | Genes | Rodents | Index Medicus | Up-Regulation | Hépatology and Gastroenterology | Oleic Acid | Down-Regulation | Lipid Metabolism | Amiodarone | Triglycerides | Liver Neoplasms | Fatty Acid Synthetase Complex, Type I | Tetracycline | Membrane Proteins | Fatty Liver | Life Sciences | Human health and pathology | Stearoyl-CoA Desaturase | Phosphoproteins | Carcinoma, Hepatocellular | Lipogenesis
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2012, Volume 7, Issue 2, pp. e31812 - e31812
The pathogenesis of fatty liver is not understood in detail, but lipid overflow as well as de novo lipogenesis (DNL) seem to be the key points of hepatocyte... 
DE-NOVO LIPOGENESIS | INSULIN-RESISTANCE | BIOLOGY | GENE-EXPRESSION | ACID SYNTHESIS | LIPID HOMEOSTASIS | CULTURED-CELLS | HEPATIC STEATOSIS | ALPHA-FETOPROTEIN | TRANSGENIC MICE | ADIPOSE-TISSUE | Organ Specificity - drug effects | Sterol Regulatory Element Binding Protein 1 - chemistry | Transcription, Genetic - drug effects | Acetyltransferases - metabolism | Adipocytes - secretion | Liver - pathology | Liver - enzymology | Fatty Liver - pathology | Humans | Male | Adipocytes - drug effects | Lipogenesis - genetics | Liver - drug effects | Body Composition - drug effects | Intra-Abdominal Fat - drug effects | Fatty Acids - metabolism | Cytokines - blood | Fatty Liver - genetics | Protein Structure, Tertiary | Insulin - pharmacology | Adiposity - drug effects | Fatty Liver - blood | Liver - metabolism | Cytokines - secretion | Insulin Resistance | Mice, Transgenic | Intra-Abdominal Fat - metabolism | Gene Expression Regulation - drug effects | Organ Size - drug effects | Phenotype | Animals | Sterol Regulatory Element Binding Protein 1 - genetics | Lipogenesis - drug effects | Stearoyl-CoA Desaturase - metabolism | Mice | Intra-Abdominal Fat - pathology | Type 2 diabetes | Enzymes | Obesity | Liver | Genes | Albumin | Amino acids | Triglycerides | Genetic transcription | Fatty acids | Fatty liver | Analysis | Physiological aspects | Insulin resistance | Protein binding | Transcription factors | Lipid composition | Adipose tissue | Body fat | Pathogenesis | Homeostasis | Lipids | Biochemistry | Adipocytes | Medical diagnosis | Accumulation | Overflow | Sterols | Transgenic animals | Rodents | Atherosclerosis | Sterol regulatory element-binding protein | Lipid metabolism | Lipogenesis | Desaturation | Hypertension | Carbohydrates | Phenotypes | Liver diseases | Internal medicine | Nutrition | Metabolism | Gene expression | Insulin | Overexpression | Epigenetics | Growth hormones | Diabetes | Metabolic disorders | Index Medicus
Journal Article
Journal of Hepatology, ISSN 0168-8278, 2010, Volume 54, Issue 6, pp. 1214 - 1223
Background & Aims Glucagon-like peptide-1 (GLP-1), a gut-derived peptide degraded by dipeptidyl peptidase-4 (DPP4), stimulates insulin secretion in response to... 
Gastroenterology and Hepatology | Incretins | Inflammatory cytokines | Liver | AMPK | Dipeptidylpetidase 4 | Lipogenesis | Glucagon-like peptide 1 | Gluconeogenesis | RAT-LIVER | METFORMIN | CELLS | HEPATOCYTES | INDUCED INSULIN-RESISTANCE | TISSUE GROWTH-FACTOR | GLUCOSE-METABOLISM | STEATOSIS | MICE | GASTROENTEROLOGY & HEPATOLOGY | AMP-Activated Protein Kinases - metabolism | Dipeptidyl Peptidase 4 - metabolism | Fatty Liver - pathology | Rats, Inbred F344 | Male | DNA Primers - genetics | Hepatocytes - metabolism | RNA, Messenger - metabolism | AMP-Activated Protein Kinases - deficiency | Liver - drug effects | Base Sequence | Lipids - blood | Inflammation Mediators - metabolism | Cyclic AMP - metabolism | Lipogenesis - physiology | Hepatocytes - drug effects | Fatty Liver - metabolism | Cytokines - metabolism | Glucagon-Like Peptide 1 - metabolism | Rats, Transgenic | Liver - metabolism | RNA, Messenger - genetics | Cells, Cultured | Glucagon-Like Peptide 1 - pharmacology | Rats | Dipeptidyl Peptidase 4 - genetics | Enzyme Activation - drug effects | Animals | Dipeptidyl Peptidase 4 - deficiency | Lipogenesis - drug effects | Metabolic Networks and Pathways - drug effects | AMP-Activated Protein Kinases - genetics | Fatty Liver - etiology | Phosphatases | Glucagon | Triglycerides | Glucose | Transforming growth factors | Fatty acids | Dextrose | Carnitine | Glucose metabolism | Angiotensin | Physiological aspects | Protein kinases | Protein binding | Index Medicus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 11/2017, Volume 127, Issue 11, pp. 4059 - 4074
Overconsumption of high-fat diet (HFD) and sugar-sweetened beverages are risk factors for developing obesity, insulin resistance, and fatty liver disease. Here... 
MEDICINE, RESEARCH & EXPERIMENTAL | BODY-WEIGHT | LIPID-METABOLISM | INDUCED METABOLIC SYNDROME | DE-NOVO LIPOGENESIS | FATTY LIVER-DISEASE | RESISTANCE | SUGAR-SWEETENED BEVERAGES | NONALCOHOLIC STEATOHEPATITIS | MICE | DIETARY FRUCTOSE | Up-Regulation | Liver - enzymology | Insulin - physiology | Humans | Transcriptional Activation | Transcriptome | Diet, High-Fat - adverse effects | Non-alcoholic Fatty Liver Disease - etiology | Male | Glucose Intolerance | Liver - drug effects | Fructose - pharmacology | Non-alcoholic Fatty Liver Disease - enzymology | Mice, Inbred C57BL | Insulin Resistance | Enzyme Induction | Glucose - pharmacology | Transcription Factors - genetics | Fructokinases - metabolism | Transcription Factors - metabolism | Animals | Signal Transduction - drug effects | Lipogenesis - drug effects | Adolescent | Fructokinases - genetics | Obesity - enzymology | Fatty Acids - biosynthesis | RNA sequencing | Glucose metabolism | Obesity | Care and treatment | Usage | Liver diseases | Insulin resistance | Research | Diagnosis | Health aspects | Drinking water | Transcription factors | Lipids | Glucose | Metabolic syndrome | Risk factors | High fat diet | Ketohexokinase | Disease resistance | Fatty liver | Hepatology | Teenagers | Supplementation | Beverages | Lipogenesis | Sugar | Enzymes | Nucleotide sequence | Dietary supplements | Ribonucleic acid--RNA | Fatty acids | Insulin | Fructose | Steatosis | Glucose tolerance | Intolerance | Diet | Diabetes | Index Medicus | Abridged Index Medicus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 11/2016, Volume 126, Issue 11, pp. 4372 - 4386
Obese, insulin-resistant states are characterized by a paradoxical pathogenic condition in which the liver appears to be selectively insulin resistant.... 
RAT-LIVER | MEDICINE, RESEARCH & EXPERIMENTAL | METABOLIC SYNDROME | DE-NOVO LIPOGENESIS | TRANSCRIPTION FACTOR FOXO1 | FATTY LIVER-DISEASE | OB/OB MICE | ELEMENT-BINDING PROTEIN | HEPATIC STEATOSIS | ADIPOSE-TISSUE | PLASMA TRIGLYCERIDES | Glucose Intolerance - metabolism | Glucose-6-Phosphatase - genetics | Fatty Liver - pathology | Humans | Male | Glucose - biosynthesis | Glucose Intolerance - pathology | Fatty Liver - chemically induced | Glycolysis - drug effects | Glycolysis - genetics | Lipogenesis - genetics | Female | Glucose Intolerance - chemically induced | Insulin - genetics | Nuclear Proteins - genetics | Fatty Liver - genetics | Forkhead Box Protein O1 - metabolism | Glucose Intolerance - genetics | Fatty Liver - metabolism | Fructose - toxicity | Insulin Resistance | Glucose - genetics | Nuclear Proteins - metabolism | Signal Transduction - genetics | Transcription Factors - genetics | Glucose-6-Phosphatase - metabolism | Mice, Knockout | Transcription Factors - metabolism | Insulin - metabolism | Animals | Signal Transduction - drug effects | Lipogenesis - drug effects | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - genetics | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - metabolism | Mice | Forkhead Box Protein O1 - genetics | Obesity | Analysis | Insulin resistance | Genetic aspects | Genetic transcription | Research | Risk factors | Protein binding | Glucose | Metabolites | Rodents | Liver | Index Medicus | Abridged Index Medicus
Journal Article
American Journal of Physiology - Endocrinology and Metabolism, ISSN 0193-1849, 12/2017, Volume 313, Issue 6, pp. E710 - E720
Stearoyl-CoA desaturase-1 (SCD1) is a key player in lipid metabolism. SCD1 catalyzes the synthesis of monounsaturated fatty acids (MUFA). MUFA are then... 
β-oxidation | Sterol receptor element binding protein-1 | Fatty acid protein modification | Stearoyl-CoA desaturase-1 | De novo lipogenesis | stearoyl-CoA desaturase-1 | PPAR-ALPHA | CELLS | PHYSIOLOGY | LIPID-METABOLISM | fatty acid protein modification | sterol receptor clement binding protein-1 | TRIACYLGLYCEROL SYNTHESIS | PROTEIN-KINASE | de novo lipogenesis | DIET | beta-oxidation | FATTY-ACID OXIDATION | LIVER | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | Humans | Liver - metabolism | Mice, Inbred C57BL | Male | Mice, Transgenic | Signal Transduction - genetics | Hepatocytes - metabolism | Stearoyl-CoA Desaturase - genetics | Hep G2 Cells | Oleic Acid - pharmacology | Animals | Lipogenesis - genetics | Liver - drug effects | Signal Transduction - drug effects | Sterol Regulatory Element Binding Protein 1 - genetics | Lipogenesis - drug effects | Lipid Metabolism - drug effects | Stearoyl-CoA Desaturase - metabolism | Lipid Metabolism - genetics | Mice | Hepatocytes - drug effects | Sterol Regulatory Element Binding Protein 1 - metabolism | Liver | Transgenic mice | Lipids | Stearoyl-CoA desaturase | Phospholipids | Triglycerides | Metabolism | Desaturase | Fatty acids | Cells | Proteins | Signaling | Hepatocytes | Rodents | Sterol regulatory element-binding protein | Oxidation | Lipid metabolism | Lipogenesis | Chemical synthesis | Index Medicus | sterol receptor element binding protein-1
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2011, Volume 6, Issue 11, pp. e26583 - e26583
Journal Article
Journal of Lipid Research, ISSN 0022-2275, 2008, Volume 49, Issue 10, pp. 2079 - 2088
Journal Article
Journal Article