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Journal of Biological Chemistry, ISSN 0021-9258, 07/2005, Volume 280, Issue 30, pp. 27872 - 27878
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 12/1995, Volume 131, Issue 6, pp. 1609 - 1622
The GPI-anchored urokinase plasminogen activator receptor (uPAR) does not internalize free urokinase (uPA). On the contrary, uPAR-bound complexes of uPA with... 
Receptors | Plasminogen activators | Lipoproteins | Internalization | Cell lines | Antibodies | Ligands | Cell membranes | Cellular immunity | Cells | Physiological aspects | Urokinase | Cell receptors | Proteins | Cellular biology | Index Medicus
Journal Article
Circulation, ISSN 0009-7322, 11/2004, Volume 110, Issue 20, pp. 3259 - 3269
Background - Weight loss in obese insulin-resistant but not in insulin-sensitive persons reduces coronary heart disease risk. To what extent changes in gene... 
Obesity | Lipoproteins | Circadian rhythm | Genes | Atherosclerosis | atherosclerosis | METABOLIC SYNDROME | CARDIAC & CARDIOVASCULAR SYSTEMS | LIPID-METABOLISM | genes | LOW-DENSITY-LIPOPROTEIN | BLOOD-PRESSURE VARIABILITY | BODY-COMPOSITION | circadian rhythm | PPAR-GAMMA | PERIPHERAL VASCULAR DISEASE | CIRCULATING OXIDIZED LDL | CORONARY-HEART-DISEASE | HEMATOLOGY | lipoproteins | obesity | TRANSGENIC MICE | ADIPOSE-TISSUE | Obesity - diet therapy | Up-Regulation | Oxidative Stress | Arteriosclerosis - genetics | Obesity - genetics | Adipose Tissue - metabolism | Myocardium - metabolism | Receptors, LDL - deficiency | Autoantibodies - analysis | Transcription, Genetic | Heart Function Tests | PPAR gamma - genetics | Arteriosclerosis - etiology | Receptors, LDL - genetics | Echocardiography | PPAR alpha - biosynthesis | Obesity - complications | Mice, Inbred C57BL | Adipose Tissue - pathology | Insulin Resistance | Lipoproteins, LDL - analysis | Aorta, Thoracic - metabolism | Gene Expression Regulation - physiology | Genotype | PPAR alpha - genetics | Inflammation | Leptin - genetics | Circadian Rhythm | PPAR gamma - biosynthesis | Mice, Knockout | Obesity - pathology | Hypertriglyceridemia - prevention & control | Arteriosclerosis - prevention & control | Animals | Weight Loss | Hypertriglyceridemia - etiology | Glucose - metabolism | Mice, Obese | Arteriosclerosis - metabolism | Mice | Leptin - deficiency | Lipoproteins, LDL - immunology | Index Medicus | Abridged Index Medicus
Journal Article
Circulation, ISSN 0009-7322, 10/2008, Volume 118, Issue 18, pp. 1837 - 1847
Background-Two macrophage ABC transporters, ABCA1 and ABCG1, have a major role in promoting cholesterol efflux from macrophages. Peritoneal macrophages... 
Lipoproteins | ABC transporters | Inflammation | Cholesterol | Atherosclerosis | atherosclerosis | CARDIAC & CARDIOVASCULAR SYSTEMS | INDUCED APOPTOSIS | CELLULAR CHOLESTEROL | NECROSIS-FACTOR-ALPHA | ABCG1(-/-) BONE-MARROW | HIGH-DENSITY-LIPOPROTEIN | APOLIPOPROTEIN-E | LIPID-ACCUMULATION | EFFLUX | inflammation | ABCA1-DEFICIENT MACROPHAGES | cholesterol | PERIPHERAL VASCULAR DISEASE | MICE | lipoproteins | ATP Binding Cassette Transporter, Sub-Family G, Member 1 | Lipoproteins - genetics | Membrane Microdomains - immunology | Signal Transduction - immunology | ATP-Binding Cassette Transporters - genetics | Mice, Mutant Strains | Lipoproteins - metabolism | ATP-Binding Cassette Transporters - metabolism | Mice, Inbred DBA | ATP Binding Cassette Transporter 1 | Macrophages - immunology | Receptors, LDL - genetics | Atherosclerosis - immunology | Atherosclerosis - physiopathology | Gene Expression Regulation - immunology | Mice, Inbred C57BL | Neutrophils - immunology | Receptors, LDL - metabolism | Toll-Like Receptor 4 - genetics | Toll-Like Receptor 4 - immunology | Toll-Like Receptor 2 - metabolism | Cholesterol - metabolism | Toll-Like Receptor 3 - metabolism | Toll-Like Receptor 4 - metabolism | Atherosclerosis - metabolism | Macrophages - metabolism | Animals | Lipopolysaccharides - pharmacology | Ligands | Macrophages - drug effects | Mice | ATP-Binding Cassette Transporters - immunology | Lipoproteins - immunology | Physiological aspects | Research | Macrophages | Gene expression | Index Medicus | Abridged Index Medicus | Toll-receptors
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology: Journal of the American Heart Association, ISSN 1079-5642, 04/2004, Volume 24, Issue 4, pp. 750 - 755
OBJECTIVE—Atherosclerosis is an inflammatory disease. Several chemokines are important for monocyte/macrophage and T-cell recruitment to the lesion. CXCL16 is... 
Scavenger receptors | Oxidized low-density lipoprotein | Interferon-γ | Chemokines | Atherosclerosis | atherosclerosis | LOW-DENSITY-LIPOPROTEIN | SR-PSOX | OXIDIZED LDL | DEFICIENT MICE | chemokines | scavenger receptors | PATHOGENESIS | CLONING | MONOCYTE-DERIVED MACROPHAGES | PERIPHERAL VASCULAR DISEASE | CD36 | LIGAND | oxidized low-density lipoprotein | HEMATOLOGY | interferon-gamma | LYMPHOCYTES | Receptors, Immunologic - physiology | Apolipoproteins E - deficiency | Receptors, Virus - biosynthesis | Humans | Monocytes - metabolism | Receptors, Virus - genetics | Arteriosclerosis - genetics | RNA, Messenger - biosynthesis | Chemotaxis, Leukocyte - drug effects | Receptors, Immunologic - biosynthesis | Membrane Proteins - physiology | T-Lymphocytes - drug effects | Receptors, Chemokine - biosynthesis | Female | Models, Animal | Receptors, CXCR | Lipoproteins, LDL - metabolism | Receptors, Chemokine - genetics | Carotid Artery Diseases - metabolism | Chemokines, CXC - biosynthesis | Receptors, Cytokine - genetics | Foam Cells - metabolism | Carotid Artery Diseases - immunology | Cell Line | Chemokine CXCL16 | Membrane Proteins - genetics | Receptors, Cytokine - biosynthesis | Mice, Inbred C57BL | Interferon-gamma - physiology | Receptors, G-Protein-Coupled - biosynthesis | Chemokines, CXC - genetics | Cholesterol - metabolism | Mice, Knockout | Monocytes - drug effects | Up-Regulation - drug effects | Membrane Proteins - biosynthesis | Animals | Receptors, Scavenger | Apolipoproteins E - genetics | Chemokines, CXC - physiology | Arteriosclerosis - metabolism | Mice | Receptors, G-Protein-Coupled - genetics | Chemokine CXCL6 | Receptors, Immunologic - genetics | Interferon-gamma - pharmacology | Receptors, CXCR6 | Index Medicus | Medical and Health Sciences | Medicin och hälsovetenskap | atherosclerosis; chemokines; interferon-gamma; oxidized low-density lipoprotein; scavenger receptors
Journal Article
Vascular Pharmacology, ISSN 1537-1891, 2012, Volume 57, Issue 1, pp. 56 - 64
Abstract Objectives Sphingosine 1-phosphate (S1P) – a lysosphingolipid present in HDL – exerts atheroprotective effects in vitro , while FTY720, a... 
Cardiovascular | Sphingosine 1-phosphate (S1P) | Inflammation | High density lipoproteins (HDL) | Atherosclerosis | CHOLESTEROL | ENDOTHELIAL CELL-ADHESION | SPHINGOSINE-1-PHOSPHATE ANALOG | HYPERCHOLESTEROLEMIA | HIGH-DENSITY-LIPOPROTEIN | MACROPHAGE ACCUMULATION | INTERFERON-GAMMA | INSULIN-RESISTANCE | PHARMACOLOGY & PHARMACY | ADIPOSE-TISSUE | Spleen - immunology | Spleen - drug effects | Body Weight - immunology | Antigens, CD - metabolism | CD4-Positive T-Lymphocytes - immunology | Lymphocyte Activation - immunology | Oxadiazoles - pharmacology | Serine Endopeptidases - immunology | CD8-Positive T-Lymphocytes - metabolism | Lymph Nodes - drug effects | Receptors, Lysosphingolipid - metabolism | Interleukin-6 - metabolism | Lymphocytes - metabolism | Propylene Glycols - pharmacology | Atherosclerosis - immunology | CD4-Positive T-Lymphocytes - metabolism | Lymph Nodes - metabolism | Receptors, LDL - metabolism | Lymph Nodes - immunology | Receptors, LDL - immunology | Atherosclerosis - metabolism | Sphingosine - pharmacology | Macrophages - metabolism | Sphingosine - analogs & derivatives | Interleukin-6 - immunology | Receptors, Lysosphingolipid - agonists | Mice | CD8-Positive T-Lymphocytes - immunology | Antigens, CD - immunology | Genes, MHC Class II - immunology | Interleukin-2 - immunology | Lymphocytes - immunology | Female | Propylene Glycols - immunology | Antigens, Differentiation, Myelomonocytic - immunology | Macrophages - immunology | Interleukin-2 - metabolism | Atherosclerosis - drug therapy | CD11b Antigen - immunology | Mice, Inbred C57BL | Proprotein Convertases - metabolism | Fingolimod Hydrochloride | Sphingosine - immunology | Proprotein Convertases - immunology | Receptors, Lysosphingolipid - immunology | Animals | Spleen - metabolism | Antigens, Differentiation, Myelomonocytic - metabolism | CD8-Positive T-Lymphocytes - drug effects | Lymphocytes - drug effects | Macrophages - drug effects | Serine Endopeptidases - metabolism | CD11b Antigen - metabolism | CD4-Positive T-Lymphocytes - drug effects | Indans - pharmacology | Hypercholesterolemia | Blood lipids | Mitogens | Low density lipoproteins | Sphingosine | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2010, Volume 107, Issue 26, pp. 12011 - 12016
Apolipoprotein E (ApoE) genotype is a powerful genetic modifier of Alzheimer's disease (AD). The ApoE4 isoform significantly reduces the mean age-of-onset of... 
Protein isoforms | Brain | Receptors | Phosphorylation | Neurons | N methyl D aspartate receptors | Long term potentiation | Recycling | Alzheimers disease | Experimental procedures | Lipoprotein receptor | Reelin | NMDA receptor | Neurodegeneration | Alzheimer's disease | LIPOPROTEIN RECEPTORS | lipoprotein receptor | CHOLESTEROL | MULTIDISCIPLINARY SCIENCES | DISEASE | neurodegeneration | BETA | Receptors, Glutamate - metabolism | Apolipoprotein E4 - genetics | LDL-Receptor Related Proteins | Humans | Receptors, N-Methyl-D-Aspartate - metabolism | Receptors, Lipoprotein - metabolism | Brain - metabolism | Neuronal Plasticity - physiology | Cell Adhesion Molecules, Neuronal - metabolism | Extracellular Matrix Proteins - metabolism | Receptors, AMPA - metabolism | Recombinant Proteins - metabolism | Apolipoprotein E4 - metabolism | Low Density Lipoprotein Receptor-Related Protein-1 - metabolism | Mice, Transgenic | Recombinant Proteins - genetics | Nerve Tissue Proteins - metabolism | Animals | Alzheimer Disease - metabolism | Long-Term Potentiation | Mice | Serine Endopeptidases - metabolism | Models, Neurological | Alzheimer Disease - genetics | In Vitro Techniques | Neuroplasticity | Methyl aspartate | Cell receptors | Physiological aspects | Research | Properties | Neurophysiology | Neurosciences | Lipoproteins | Rodents | Index Medicus | Biological Sciences
Journal Article
Journal Article
Journal Article
Nature, ISSN 0028-0836, 05/2001, Volume 411, Issue 6835, pp. 321 - 325
Wnt glycoproteins have been implicated in diverse processes during embryonic patterning in metazoa. They signal through frizzled-type... 
SIGNAL-TRANSDUCTION | CERBERUS | ACTIVATION | XENOPUS | ANTAGONIST | HEAD INDUCTION | MULTIDISCIPLINARY SCIENCES | SECRETED PROTEINS | WNT | EXPRESSION | SPEMANN ORGANIZER | Receptors, Immunologic - chemistry | Cytoskeletal Proteins - genetics | Humans | Embryo, Nonmammalian - metabolism | Substrate Specificity | Embryo, Nonmammalian - embryology | Wnt Proteins | RNA, Messenger - metabolism | Receptors, LDL - chemistry | Recombinant Fusion Proteins - metabolism | Receptors, Immunologic - antagonists & inhibitors | Recombinant Fusion Proteins - antagonists & inhibitors | Cytoskeletal Proteins - metabolism | Low Density Lipoprotein Receptor-Related Protein-1 | Head - embryology | Binding Sites | Protein Structure, Tertiary | Proto-Oncogene Proteins - metabolism | Cell Line | Proto-Oncogene Proteins - antagonists & inhibitors | Receptors, LDL - genetics | Xenopus laevis - embryology | Low Density Lipoprotein Receptor-Related Protein-6 | Signal Transduction | beta Catenin | Intercellular Signaling Peptides and Proteins | RNA, Messenger - genetics | Receptors, LDL - antagonists & inhibitors | Trans-Activators | Zebrafish Proteins | Receptors, Cell Surface - metabolism | Receptors, LDL - metabolism | Embryonic Induction | Proto-Oncogene Proteins - genetics | Xenopus Proteins | Precipitin Tests | Proteins - genetics | Animals | Proteins - metabolism | Protein Binding | Proteins - chemistry | Receptors, Immunologic - genetics | Proteins - antagonists & inhibitors | Receptors, Immunologic - metabolism | Receptors, Cell Surface - genetics | Sequence Deletion - genetics | Proteins | Cellular biology | Embryos | Genes | Patterning | Receptors | Inhibitors | Modulation | Signalling | Inducers | Dkk2 protein | b-catenin | LDL-receptor-related protein 6 | Wnt protein | LRP6 protein | Dkk1 protein | Index Medicus
Journal Article