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Journal Article
Journal of Hepatology, ISSN 0168-8278, 2012, Volume 58, Issue 1, pp. 155 - 168
Summary Bile acid (BA) transporters are critical for maintenance of the enterohepatic BA circulation where BAs exert their multiple physiological functions... 
Gastroenterology and Hepatology | Gallstones | Liver cancer | Bile acids | Fatty liver disease | Cholestasis | Liver regeneration | RAT-LIVER | SALT EXPORT PUMP | GROWTH-FACTOR 19 | ORGANIC ANION TRANSPORTERS | 90-PERCENT PARTIAL-HEPATECTOMY | URSODEOXYCHOLIC ACID | PRIMARY BILIARY-CIRRHOSIS | FARNESOID-X-RECEPTOR | GASTROENTEROLOGY & HEPATOLOGY | PHOSPHOLIPID-ASSOCIATED CHOLELITHIASIS | FAMILIAL INTRAHEPATIC CHOLESTASIS | Animals | Carrier Proteins - metabolism | Cholestasis - metabolism | Membrane Glycoproteins - metabolism | Humans | Liver - metabolism | Bile Acids and Salts - metabolism | Liver Diseases - metabolism | Liver Regeneration - physiology | Receptors, Cytoplasmic and Nuclear - metabolism | Drug resistance in microorganisms | Corticosteroids | Glucagon | Calcifediol | Ursodiol | Deoxycholic acid | Epidermal growth factor | Vitamin D | Physiological aspects | Fibroblast growth factors | Alfacalcidol | IBABP (FABP6, ILBP), intestinal bile acid-binding protein, fatty acid-binding protein 6 | PFIC, progressive familial intrahepatic cholestasis | TNFα, tumor necrosis factor α | 3 (human) | SRC2, p160 steroid receptor coactivator | NAFLD, non-alcoholic fatty liver disease | BA, bile acid | bile acid receptor | 8, cholesterol efflux pump, ATP-binding cassette, subfamily G, member 5 | UDCA, ursodeoxycholic acid | LRH-1 (NR5A2), liver receptor homolog-1 | LCA, lithocholic acid | LXRα (NR1H3), liver X receptor alpha | PPARγ (NR1C3), peroxisome proliferator-activated receptor gamma | OSTαβ, organic solute transporter alpha | ABCG5 | AMPK, AMP activated protein kinase | NASH, non-alcoholic steatohepatitis | SHP (NR0B2), short heterodimer partner | OATP1A2 (SLCO1A2, OATP1, OATP-A, SLC21A3), solute carrier organic anion transporter family, member 1A2 | EGFR, epidermal growth factor receptor | IL6, interleukin 6 | TGR5, G protein-coupled bile acid receptor | PH, partial hepatectomy | AE2, anion exchanger 2 | PSC, primary sclerosing cholangitis | OATP1B1 (SLCO1B1, OATP2, OATP-C, SLC21A6), solute carrier organic anion transporter family, member 1B1 | RARα (NR1B1), retinoic acid receptor alpha | GLP-1, glucagon like peptide 1 | VDR (NR1I1), vitamin D receptor. Please note that for the convenience of better readability and clarity, abbreviations for transporters and nuclear receptors were capitalized throughout this article when symbols were identical for human and rodents | MRP2 (ABCC2), multidrug resistance-associated protein 2, ATP-binding cassette, subfamily C, member 2 | NTCP (SLC10A1), sodium | CAR (NR1I3), constitutive androstane receptor | taurocholate cotransporting polypeptide, solute carrier family 10, member 1 | PPARα (NR1C1), peroxisome proliferator-activated receptor alpha | Review | GR (NR3C1), glucocorticoid receptor | Bile acids, Cholestasis, Fatty liver disease, Gallstones, Liver regeneration, Liver cancer | 19, fibroblast growth factor 15 | Mdr2 | ICP, intrahepatic cholestasis of pregnancy | BRIC, benign recurrent intrahepatic cholestasis | OATP1B3 (SLCO1B3, OATP8, SLC21A8), solute carrier organic anion transporter family, member 1B3 | MRP3 (ABCC3), multidrug resistance-associated protein 3, ATP-binding cassette, subfamily C, member 3 | beta | MDR1 (ABCB1), p-glycoprotein, ATP-binding cassette, subfamily B, member 1 | norUDCA, norursodeoxycholic acid | 6-ECDCA, 6-ethylchenodeoxycholic acid | FXR (NR1H4), farnesoid X receptor | BCRP (ABCG2), breast cancer resistance protein, ATP-binding cassette, subfamily G, member 2 | HNF4α (NR2A1), hepatocyte nuclear factor 4 alpha | PBC, primary biliary cirrhosis | MDR3 (ABCB4), multidrug resistance protein 2 (rodents) | HNF1α, hepatocyte nuclear factor 1 alpha | NR, nuclear receptor | FGF15 | RXRα (NR2B1), retinoid X receptor alpha | PXR (NR1I2), pregnane X receptor | BSEP (ABCB11), bile salt export pump | HCC, hepatocellular carcinoma | MRP4 (ABCC4), multidrug resistance-associated protein 4, ATP-binding cassette, subfamily C, member 4 | TPN, total parenteral nutrition
Journal Article
Journal Article
Journal Article
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 2008, Volume 233, Issue 2, pp. 193 - 202
Chlordecone (CD) is one of many banned organochlorine (OC) insecticides that are widespread persistent organic pollutants. OC insecticides alter lipid... 
Estrogen receptor α | Liver X receptors | Chlordecone | Pregnane X receptor | Organochlorine insecticides | Apolipoproteins | Cholesterol | CELLS | LIPID-METABOLISM | RAINBOW-TROUT | NUCLEAR RECEPTORS | DEFICIENT MICE | INDUCTION | LXR-ALPHA | LIVER | PHARMACOLOGY & PHARMACY | Estrogen receptor alpha | TOXICOLOGY | BINDING | BILE-ACIDS | Humans | Microsomes, Liver - metabolism | Apolipoprotein B-48 - metabolism | Chlordecone - toxicity | Male | Receptors, Steroid - agonists | DNA-Binding Proteins - metabolism | Dose-Response Relationship, Drug | Insecticides - administration & dosage | Apolipoprotein B-100 - metabolism | Estrogen Receptor alpha - agonists | Microsomes, Liver - drug effects | Liver X Receptors | Lipoproteins - metabolism | Membrane Proteins - metabolism | Cytochrome P-450 CYP3A - drug effects | Homeostasis - drug effects | Orphan Nuclear Receptors | Apolipoprotein A-I - drug effects | Cell Line | Chlordecone - administration & dosage | Receptors, Cytoplasmic and Nuclear - drug effects | Mice, Inbred C57BL | DNA-Binding Proteins - drug effects | Apolipoprotein A-I - metabolism | Cholesterol - metabolism | Animals | Cytochrome P-450 CYP3A - metabolism | Membrane Proteins - drug effects | Genes, Reporter - drug effects | Mice | Transcription Factors | Lipoproteins - drug effects | Apolipoprotein B-100 - drug effects | Apolipoprotein B-48 - drug effects | Insecticides - toxicity | Receptors, Cytoplasmic and Nuclear - metabolism | Proteolipids | Lipoproteins | Estrogen | Physiological aspects | Homeostasis | Phenols | Blood lipoproteins | Organic compounds | Index Medicus | ESTROGENS | HOMEOSTASIS | ORGANIC CHLORINE COMPOUNDS | CHOLESTEROL | POLLUTANTS | CARBON 14 | RATS | APOLIPOPROTEINS | 60 APPLIED LIFE SCIENCES | METABOLISM | DOSES | IN VITRO | MICROSOMES | TISSUE DISTRIBUTION | ESTERS | MICE | RECEPTORS | INSECTICIDES
Journal Article
Journal Article
Clinical and Experimental Pharmacology and Physiology, ISSN 0305-1870, 12/2014, Volume 41, Issue 12, pp. 1023 - 1030
Summary Adenosine triphosphate‐binding cassette transporter A1 (ABCA1) and ABCG1 play crucial roles in reverse cholesterol transport, and have... 
liver X receptor α | reverse cholesterol transport | angiotensin‐(1–7) | adenosine triphosphate‐binding cassette transporter A1 | adenosine triphosphate‐binding cassette transporter G1 | Liver X receptor α | Adenosine triphosphate-binding cassette transporter G1 | Adenosine triphosphate-binding cassette transporter A1 | Angiotensin-(1-7) | Reverse cholesterol transport | PHYSIOLOGY | LXR | INCREASES | ATHEROSCLEROSIS | MECHANISMS | liver X receptor alpha | FOAM CELLS | adenosine triphosphate-binding cassette transporter G1 | SMOOTH-MUSCLE | EFFLUX | adenosine triphosphate-binding cassette transporter A1 | ATHEROPROTECTION | INFLAMMATION | angiotensin-(1-7) | PHARMACOLOGY & PHARMACY | RNA, Small Interfering - genetics | ATP Binding Cassette Transporter, Sub-Family G, Member 1 | Atherosclerosis - genetics | Humans | RNA, Messenger - genetics | Proto-Oncogene Proteins - genetics | Up-Regulation - genetics | Signal Transduction - genetics | Cholesterol - metabolism | Orphan Nuclear Receptors - genetics | Macrophages - metabolism | ATP-Binding Cassette Transporters - genetics | Angiotensin I - genetics | Membrane Transport Proteins - genetics | Liver X Receptors | Cell Line, Tumor | Receptors, G-Protein-Coupled - genetics | Peptide Fragments - genetics | ATP Binding Cassette Transporter 1 - genetics | RNA | Liver | Atherosclerosis | Angiotensin | Muscle proteins | Macrophages | Adenosine triphosphate
Journal Article