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Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 03/2014, Volume 34, Issue 3, pp. 487 - 498
Low-density lipoprotein receptor–related protein-1 (LRP1) is a large endocytic and signaling receptor that is widely expressed. In the liver, LRP1 plays an... 
Extracellular matrix | LRP1 | fVIII | Elastin | Aneurysm | aneurysm | GROWTH-FACTOR-RECEPTOR | FACTOR-VIII | DEPENDENT PHOSPHATIDYLINOSITOL 3-KINASE | MUSCLE-CELL PROLIFERATION | elastin | VON-WILLEBRAND-FACTOR | BLOOD-BRAIN-BARRIER | ALPHA-2-MACROGLOBULIN RECEPTOR | APOLIPOPROTEIN-E | PLASMINOGEN-ACTIVATOR | UROKINASE RECEPTOR | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | extracellular matrix | Muscle, Smooth, Vascular - metabolism | Humans | Low Density Lipoprotein Receptor-Related Protein-1 - chemistry | Extracellular Matrix - metabolism | Low Density Lipoprotein Receptor-Related Protein-1 - physiology | Tumor Suppressor Proteins - deficiency | Tumor Suppressor Proteins - genetics | Receptors, LDL - deficiency | Models, Animal | Lipoproteins, LDL - metabolism | Peptide Hydrolases - metabolism | von Willebrand Factor - metabolism | Elastin - metabolism | Receptors, LDL - genetics | Signal Transduction | Liver - metabolism | Transforming Growth Factor beta - physiology | Models, Molecular | Organ Specificity | Atherosclerosis - metabolism | Endocytosis - physiology | Mice, Knockout | Tumor Suppressor Proteins - physiology | Macrophages - metabolism | Platelet-Derived Growth Factor - metabolism | Animals | Protein Conformation | Mice | Blood Coagulation - physiology | Factor VIII - metabolism | Receptors, LDL - physiology | Thromboplastin - metabolism | Aneurysm - prevention & control
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2012, Volume 109, Issue 9, pp. 3510 - 3515
A 30-d course of oral administration of a semipurif ied extract of the root of Withania somnifera consisting predominantly of withanolides and withanosides... 
Oligomers | Anger | Pathology | Brain | Messenger RNA | Liver | Medical treatment | LDL lipoproteins | Amyloids | Alzheimers disease | Herbal extract | Neurodegenerative disease | Dementia | CLEARANCE | neurodegenerative disease | MEMORY | MULTIDISCIPLINARY SCIENCES | herbal extract | AMYLOID-BETA-PEPTIDE | dementia | BLOOD-BRAIN-BARRIER | SYNAPTIC PLASTICITY | STRATEGIES | Up-Regulation | Liver - pathology | Male | Low Density Lipoprotein Receptor-Related Protein-1 - physiology | Low Density Lipoprotein Receptor-Related Protein-1 - genetics | Neprilysin - biosynthesis | Amyloid beta-Peptides - blood | Alzheimer Disease - pathology | Brain - metabolism | Liver - drug effects | Microglia - pathology | Neprilysin - genetics | Phytotherapy | Drug Evaluation, Preclinical | Neprilysin - physiology | Disease Models, Animal | Oligonucleotides, Antisense - pharmacology | Microglia - drug effects | Plaque, Amyloid - pathology | Administration, Oral | Liver - metabolism | Alzheimer Disease - drug therapy | Presenilin-1 - genetics | Mice, Transgenic | Plant Extracts - isolation & purification | Low Density Lipoprotein Receptor-Related Protein-1 - biosynthesis | Maze Learning - drug effects | Organ Specificity | Brain - drug effects | Amyloid beta-Protein Precursor - genetics | Animals | Plant Roots - chemistry | Brain - pathology | Mice | Plant Extracts - therapeutic use | Alzheimer Disease - blood | Withania - chemistry | Prevention | Physiological aspects | Alzheimer's disease | Health aspects | Low density lipoproteins | Biological Sciences
Journal Article
Journal Article
The American Journal of Human Genetics, ISSN 0002-9297, 11/2011, Volume 89, Issue 5, pp. 619 - 627
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 09/2012, Volume 287, Issue 37, pp. 31104 - 31115
In Helicobacter pylori infection, vacuolating cytotoxin (VacA)-induced mitochondrial damage leading to apoptosis is believed to be a major cause of cell death.... 
MITOCHONDRIAL APOPTOSIS | VACUOLATING-CYTOTOXIN | TOXIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | LIPID RAFTS | GASTRIC EPITHELIAL-CELLS | DEATH | T-CELL | ANION-SELECTIVE CHANNELS | TUMOR-GROWTH | TYROSINE-PHOSPHATASE-BETA | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Humans | Helicobacter pylori - genetics | Stomach - metabolism | Low Density Lipoprotein Receptor-Related Protein-1 - genetics | Autophagy | Helicobacter Infections - pathology | Amino Acid Chloromethyl Ketones - pharmacology | Epithelium - microbiology | Helicobacter Infections - metabolism | Cell Line | Receptor-Like Protein Tyrosine Phosphatases, Class 5 - genetics | Epithelium - pathology | Stomach - pathology | Epithelium - metabolism | Low Density Lipoprotein Receptor-Related Protein-1 - metabolism | Helicobacter Infections - genetics | Fibronectins - metabolism | Poly(ADP-ribose) Polymerases - metabolism | Poly(ADP-ribose) Polymerases - genetics | Autophagy-Related Protein 5 | Helicobacter pylori - metabolism | Cysteine Proteinase Inhibitors - pharmacology | Bacterial Proteins - metabolism | Fibronectins - genetics | Stomach - microbiology | Receptor-Like Protein Tyrosine Phosphatases, Class 5 - metabolism | Apoptosis | Vacuolating Cytotoxin (VacA) | Receptors | Microbiology | Helicobacter pylori | LRP1 | Toxins | Cell Biology
Journal Article
Journal Article