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1. Full Text Anti-LRP5/6 VHHs promote differentiation of Wnt-hypersensitive intestinal stem cells
by Fenderico, Nicola and van Scherpenzeel, Revina C and Goldflam, Michael and Proverbio, Davide and Jordens, Ingrid and Kralj, Tomica and Stryeck, Sarah and Bass, Tarek Z and Hermans, Guy and Ullman, Christopher and Aastrup, Teodor and Gros, Piet and Maurice, Madelon M
Nature communications, ISSN 2041-1723, 01/2019, Volume 10, Issue 1, pp. 365 - 365
Low Density Lipoprotein Receptor-Related Protein-6/antagonists & inhibitors | Cell Proliferation | Humans | Crystallography, X-Ray | Journal Article | Single-Domain Antibodies/chemistry | Intestine, Small/cytology | HEK293 Cells | Transcription, Genetic | Cell Differentiation | Protein Interaction Domains and Motifs | beta Catenin/genetics | Binding Sites | Stem Cells/cytology | Wnt3A Protein/genetics | Fibroblasts/cytology | Gene Expression Regulation | Models, Molecular | Animals | Protein Conformation, beta-Strand | Research Support, Non-U.S. Gov't | Cell Line, Tumor | Protein Binding | Low Density Lipoprotein Receptor-Related Protein-5/antagonists & inhibitors | Mice | Organoids/cytology | Ubiquitin-Protein Ligases/genetics | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Wnt3A Protein - metabolism | Low Density Lipoprotein Receptor-Related Protein-5 - genetics | Single-Domain Antibodies - metabolism | Low Density Lipoprotein Receptor-Related Protein-5 - chemistry | Stem Cells - cytology | Low Density Lipoprotein Receptor-Related Protein-6 - chemistry | Stem Cells - metabolism | Low Density Lipoprotein Receptor-Related Protein-6 - genetics | Organoids - metabolism | Low Density Lipoprotein Receptor-Related Protein-5 - antagonists & inhibitors | Fibroblasts - metabolism | Wnt3A Protein - genetics | Organoids - cytology | Ubiquitin-Protein Ligases - metabolism | Low Density Lipoprotein Receptor-Related Protein-6 - antagonists & inhibitors | beta Catenin - metabolism | beta Catenin - genetics | Low Density Lipoprotein Receptor-Related Protein-6 - metabolism | Intestine, Small - cytology | Single-Domain Antibodies - chemistry | Fibroblasts - drug effects | Intestine, Small - drug effects | Low Density Lipoprotein Receptor-Related Protein-5 - metabolism | Organoids - drug effects | Stem Cells - drug effects | Fibroblasts - cytology | Intestine, Small - metabolism | Single-Domain Antibodies - genetics | Ubiquitin-Protein Ligases - genetics | Uncertainty | Organoids | Animal behavior | Neural networks | Circuits | Stem cells | Inactivation | Structural analysis | Index Medicus
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2. Full Text Low-density lipoprotein receptor-related proteins in a novel mechanism of axon guidance and peripheral nerve regeneration
by Landowski, Lila M and Pavez, Macarena and Brown, Lachlan S and Gasperini, Robert and Taylor, Bruce V and West, Adrian K and Foa, Lisa
The Journal of biological chemistry, ISSN 0021-9258, 01/2016, Volume 291, Issue 3, pp. 1092 - 1102
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Male | Axons - physiology | Ganglia, Spinal - cytology | Low Density Lipoprotein Receptor-Related Protein-2 - agonists | Peripheral Nervous System Diseases - physiopathology | Low Density Lipoprotein Receptor-Related Protein-1 - genetics | Low Density Lipoprotein Receptor-Related Protein-2 - antagonists & inhibitors | Peripheral Nerves - drug effects | Peripheral Nerves - physiology | RNA Interference | Peripheral Nerves - cytology | Low Density Lipoprotein Receptor-Related Protein-2 - genetics | Neurogenesis - drug effects | Epidermis - innervation | Metallothionein - therapeutic use | Low Density Lipoprotein Receptor-Related Protein-1 - antagonists & inhibitors | Nerve Tissue Proteins - antagonists & inhibitors | Rabbits | Epidermis - drug effects | Nerve Tissue Proteins - agonists | Cells, Cultured | Axons - drug effects | Ganglia, Spinal - physiology | Low Density Lipoprotein Receptor-Related Protein-1 - metabolism | Low Density Lipoprotein Receptor-Related Protein-2 - metabolism | Chemotaxis - drug effects | Nerve Tissue Proteins - genetics | Rats, Sprague-Dawley | Nerve Tissue Proteins - metabolism | Animals | Growth Cones - metabolism | Low Density Lipoprotein Receptor-Related Protein-1 - agonists | Calcium Signaling - drug effects | Metallothionein - pharmacology | Nerve Regeneration - drug effects | Ligands | Growth Cones - drug effects | Ganglia, Spinal - drug effects | Peripheral Nervous System Diseases - drug therapy | Index Medicus | growth cone | LRP1 | regeneration | Neurobiology | cell signaling | axon | neurite outgrowth | LRP2 | metallothionein
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3. Full Text WNT signaling in bone homeostasis and disease: from human mutations to treatments
by Baron, Roland and Kneissel, Michaela
Nature medicine, ISSN 1078-8956, 02/2013, Volume 19, Issue 2, pp. 179 - 192
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Low Density Lipoprotein Receptor-Related Protein-6 - physiology | Low Density Lipoprotein Receptor-Related Protein-5 - physiology | Bone Density | Bone Morphogenetic Proteins - physiology | Humans | Homeostasis | Wnt Signaling Pathway - physiology | Bone Development | Animals | Hematopoiesis | Bone and Bones - metabolism | Mice | beta Catenin - physiology | Mutation | Osteoporosis | Gene mutations | Physiological aspects | Bones | Genetic aspects | Research | Health aspects | Density | Risk factors | Signaling | Index Medicus
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4. Full Text Very-Low-Density Lipoprotein–Associated Apolipoproteins Predict Cardiovascular Events and Are Lowered by Inhibition of APOC-III
by Pechlaner, Raimund, MD, PhD and Tsimikas, Sotirios, MD and Yin, Xiaoke, PhD and Willeit, Peter, MD, PhD and Baig, Ferheen, MSc and Santer, Peter, MD and Oberhollenzer, Friedrich, MD and Egger, Georg, MD and Witztum, Joseph L., MD and Alexander, Veronica J., PhD and Willeit, Johann, MD and Kiechl, Stefan, MD and Mayr, Manuel, MD, PhD
Journal of the American College of Cardiology, ISSN 0735-1097, 2017, Volume 69, Issue 7, pp. 789 - 800
Cardiovascular | Internal Medicine | mass spectrometry | triglycerides | proteomics | lipidomics | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Apolipoprotein C-III - antagonists & inhibitors | Prospective Studies | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Male | Apolipoproteins - blood | Incidence | Lipoproteins, VLDL - blood | Mass Spectrometry | Cardiovascular Diseases - blood | Cardiovascular Diseases - epidemiology | Female | Aged | Medical colleges | Research institutes | Blood lipids | Apolipoproteins | Low density lipoproteins | Analysis | Mass spectrometry | Heart attack | Blood proteins | Studies | Lipids | Low density lipoprotein | Statins | Index Medicus | Abridged Index Medicus | HDL-C, high-density lipoprotein cholesterol | MS, mass spectrometry | PC, phosphatidylcholine | LDL-C, low-density lipoprotein cholesterol | CE, cholesterol ester | CVD, cardiovascular disease | DAG, diacylglycerol | VLDL, very-low-density lipoprotein | TAG, triacylglycerol | TG, triglyceride | TRL, triglyceride-rich lipoprotein | apo, apolipoprotein | FCS, familial chylomicronemia syndrome | MRM, multiple reaction monitoring | HDL, high-density lipoprotein | LDL, low-density lipoprotein | Original Investigation
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5. Full Text LDL Receptor-Related Protein 1: Unique Tissue-Specific Functions Revealed by Selective Gene Knockout Studies
by Anna P. Lillis and Lauren B. Van Duyn and Joanne E. Murphy-Ullrich and Dudley K. Strickland
Physiological Reviews, ISSN 0031-9333, 07/2008, Volume 88, Issue 3, pp. 887 - 918
Life Sciences & Biomedicine | Physiology | Science & Technology | Blood Vessels - metabolism | Humans | Low Density Lipoprotein Receptor-Related Protein-1 - chemistry | Blood Proteins - metabolism | Low Density Lipoprotein Receptor-Related Protein-1 - genetics | Integrins - metabolism | Inflammation - metabolism | Gene Deletion | Neurons - metabolism | LDL-Receptor Related Protein-Associated Protein - metabolism | Liver - metabolism | Low Density Lipoprotein Receptor-Related Protein-1 - metabolism | Models, Molecular | Signal Transduction - genetics | Phagocytes - metabolism | Blood-Brain Barrier - metabolism | Mice, Knockout | Protein Transport | Animals | Immune System - metabolism | Adipocytes - metabolism | Ligands | Protein Conformation | Mice | Phagocytosis | Cell Movement | Genetic research | Research | Molecular chaperones | Structure | Low density lipoproteins | Studies | Anatomy & physiology | Kinases | Tissues | Low density lipoprotein | Genes | Index Medicus
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