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Neurobiology of Disease, ISSN 0969-9961, 2014, Volume 68, Issue 100, pp. 66 - 77
Abstract Rett syndrome (RTT) is a rare neurodevelopmental disorder affecting almost exclusively females, caused in the overwhelming majority of the cases by... 
Neurology | Lipid peroxidation | Oxidative stress | Brain damage | Neurodevelopmental disorder | Murine models | Rett syndrome | IRON | CPG-BINDING PROTEIN-2 | NEUROSCIENCES | CHOLESTEROL-METABOLISM | MECP2 MUTANT MICE | MOUSE MODEL | DISEASE | ANIMAL-MODELS | DISORDER | DYSFUNCTION | STRESS | Arachidonic Acid - metabolism | Rett Syndrome - complications | Gas Chromatography-Mass Spectrometry | Mice, Inbred C57BL | Neuroprostanes - metabolism | Oxidative Stress - physiology | Male | Mice, Transgenic | Aldehydes - metabolism | Mutation - genetics | Methyl-CpG-Binding Protein 2 - genetics | Animals | Isoprostanes - metabolism | Analysis of Variance | Nestin - genetics | Brain Injuries - blood | Female | Mice | Brain Injuries - etiology | Rett Syndrome - blood | Rett Syndrome - genetics | Brain Injuries - pathology | Disease Models, Animal | Docosahexaenoic Acids - metabolism | Models | Analysis | Protein binding | Index Medicus | Organic chemistry | Chemical Sciences | OS, oxidative stress | Mecp2 | y, hemizygous null mice | NPBI, non-protein-bound iron | Mecp2, methyl-CpG-binding protein 2 — mouse protein | CRE, Cre-Recombinase | AdA, adrenic acid | AUs, arbitrary units | ARA, arachidonic acid | 4-HNE PAs, 4-HNE protein adducts | PSV, Preserved Speech Variant | Mecp2, methyl-CpG-binding protein 2 — mouse gene | wt, wild type | wt-Cre, wild type expressing Cre recombinase | MECP2, methyl-CpG-binding protein 2 — human gene | y, symptomatic Mecp2 308-mutated hemizygous males | ROS, reactive oxygen species | F2-IsoPs, F2-isoprostanes | MeCP2, methyl-CpG-binding protein 2 — human protein | y, Lox | F2-dihomo-IsoPs, F2-dihomo-isoprostanes | 4-HNE PAs, 4-hydroxy-2-nonenal protein adducts | Mecp2 stop | y NestinCre, rescued Lox | ASDs, autism spectrum disorders | F4-NeuroPs, F4-neuroprostanes | Mecp2 308 | stop pre-symptomatic hemizygous mice | x, symptomatic Mecp2 308-mutated females | DHA, docosahexaenoic acid | PUFAs, polyunsaturated fatty acids | BDNF, brain-derived neurotrophic factor | IsoPs, isoprostanes | RTT, Rett syndrome | stop mice (Mecp2 reactivated in the nervous tissue) | 4-HNE, 4-hydroxy-2-nonenal
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 10/2018, Volume 28, Issue 18, pp. 3113 - 3118
Lysyl oxidase (LOX) enzymes as potential drug targets maintain constant attention in the therapy of fibrosis, cancer and metastasis. In order to measure the... 
Novel LOX family inhibitors | 2D ligand-based virtual screening | LOX targeted library | Lysyl oxidase | Fluorescent LOX assay | FIBROSIS | CHEMISTRY, MEDICINAL | SIMILARITY SEARCH | CHEMISTRY, ORGANIC | CANCER | DERIVATIVES | Oxidases | Metastasis | Medical screening | Melanoma | Index Medicus
Journal Article
Developmental Biology, ISSN 0012-1606, 2009, Volume 334, Issue 1, pp. 174 - 185
Journal Article
ISSN 0950-1991, 2017
Airway stem cells slowly self-renew and produce differentiated progeny to maintain homeostasis throughout the lifespan of an individual. Mutations in the... 
Cre-Lox | lung | mouse | trachea | progenitor
Journal Article
CANCER SCIENCE, ISSN 1349-7006, 01/2018, Volume 109, pp. 581 - 581
Conference Proceeding
Journal Article
FASEB Journal, ISSN 0892-6638, 08/2018, Volume 32, Issue 8, pp. 4459 - 4469
Vascular smooth muscle cells (VSMCs) transdifferentiate into osteoblast-like cells during vascular calcification, inducing active remodeling and calcification... 
Extracellular matrix | BAPN | PLOD1 | LOX | Dipyridyl | CALCIUM-PHOSPHATE DEPOSITION | ATHEROSCLEROTIC LESIONS | OXIDATIVE STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | LYSYL OXIDASE LOX | CULTURE | CELL BIOLOGY | dipyridyl | MYOCARDIAL COLLAGEN | CORONARY-ARTERY CALCIFICATION | STIFFNESS | OSTEOBLASTS | BIOLOGY | EXPRESSION | extracellular matrix | Index Medicus
Journal Article
Cellular & molecular biology letters, ISSN 1425-8153, 2019, Volume 24, Issue 1, pp. 39 - 39
The aim of this study was to investigate the effect of human umbilical vein endothelial cells on epithelial-to-mesenchymal transition of the cervical cancer... 
Co-culture | NOTCH/LOX/SNAIL pathway | EMT | Cervical cancer | HUVECs | SiHa cells
Journal Article
Development (Cambridge, England), ISSN 0950-1991, 04/2018, Volume 145, Issue 8, pp. dev157511 - dev157511
In the adult central nervous system, endothelial and neuronal cells engage in tight cross-talk as key components of the so-called neurovascular unit.... 
Angiogenesis | Hif2a | Epas1 | Neuroprogenitor | Endostatin | Retina | Cre/lox | PROGENITOR CELLS | MIGRATION | VEGF | DEVELOPMENTAL BIOLOGY | HYPOXIA-INDUCIBLE FACTORS | GENE | RCS RAT MODEL | DIFFERENTIATION | EXPRESSION | Retinal Pigment Epithelium - metabolism | Cell Proliferation | Retinal Vessels - innervation | Vascular Endothelial Growth Factor A - metabolism | Neural Stem Cells - cytology | Retinal Ganglion Cells - metabolism | Retinal Pigment Epithelium - growth & development | Retinal Ganglion Cells - cytology | Basic Helix-Loop-Helix Transcription Factors - metabolism | Gene Expression Regulation, Developmental | Basic Helix-Loop-Helix Transcription Factors - deficiency | Astrocytes - cytology | Basic Helix-Loop-Helix Transcription Factors - genetics | Retinal Vessels - metabolism | Signal Transduction | Endostatins - metabolism | Neovascularization, Physiologic - genetics | Mice, Inbred C57BL | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Mice, Transgenic | Mice, Knockout | Animals | Retinal Vessels - growth & development | Mice | Neural Stem Cells - metabolism | Astrocytes - metabolism | Hypoxia-inducible factors | Parkinson's disease | LOX gene | Neurodegenerative diseases | Erythropoietin | Central nervous system | Blood vessels | Homeostasis | Endothelial cells | Neural stem cells | Hypoxia | Angiogenesis inhibitors | Vascular endothelial growth factor | Alzheimer's disease | Movement disorders | Index Medicus | lox | 204 | 205 | Cre
Journal Article
Genes, ISSN 2073-4425, 05/2019, Volume 10, Issue 5, p. 374
Gene modification is a promising tool for plant breeding, and gradual application from the laboratory to the field. Selectable marker genes (SMG) are required... 
transgenic maize | egfp | recombination | cre/lox | marker-free | heat-shock
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2016, Volume 11, Issue 6, pp. e0157801 - e0157801
Background Due to the poor prognosis for advanced renal cell carcinoma (RCC), there is an urgent need for new therapeutic targets and for prognostic markers to... 
REAL-TIME PCR | CANCER-CELLS | LUNG-CANCER | METASTASIS | EPITHELIAL-CELLS | MULTIDISCIPLINARY SCIENCES | UROLOGICAL TUMORS | GENE-EXPRESSION | TUMOR-SUPPRESSOR | LYSYL-OXIDASE | MESENCHYMAL TRANSITION | Kidney Neoplasms - genetics | Prognosis | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Carcinoma, Renal Cell - genetics | Male | Gene Expression Profiling | Cell Movement - genetics | Kidney Neoplasms - diagnosis | Neoplasm Metastasis | Neoplasm Grading | RNA Interference | Aged, 80 and over | Adult | Female | RNA, Messenger - genetics | Kaplan-Meier Estimate | Proportional Hazards Models | Kidney Neoplasms - mortality | Carcinoma, Renal Cell - mortality | Carcinoma, Renal Cell - diagnosis | Cell Line, Tumor | Aged | MicroRNAs - genetics | Neoplasm Staging | Care and treatment | DNA microarrays | MicroRNA | Analysis | Development and progression | Genetic aspects | Carcinoma, Renal cell | Metastasis | Health aspects | Index Medicus | Post-transcription | Regulators | Tissue analysis | Kinases | Carcinogenesis | Urology | Metastases | Angiogenesis | Carcinogens | Bioindicators | Inhibition | Medical research | Therapeutic applications | MiRNA | Breast cancer | Functional analysis | Gene expression | Protein arrays | MicroRNAs | Liquid oxygen | Medical prognosis | Biomarkers | Hypoxia | Diagnostic systems | Cell migration | Clear cell-type renal cell carcinoma | Tumors | Apoptosis
Journal Article
Advances in Experimental Medicine and Biology, ISSN 0065-2598, 10/2016, Volume 854, pp. 725 - 730
Journal Article
OncoImmunology, ISSN 2162-4011, 06/2015, Volume 4, Issue 6, pp. e1008371 - e1008371
Journal Article