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1981, 1, ISBN 9780849361852, 174
It has only been a short time since the existence of suppressor cells was demonstrated, yet in this period of time a great deal of information has been... 
Suppressor cells | Lymphokines | Lymphocytes T suppresseurs | Crop Science
Book
The Journal of clinical investigation, ISSN 0021-9738, 07/2008, Volume 118, Issue 7, pp. 2427 - 2437
Cancer is associated with immune deficiency, but the biologic basis of this is poorly defined. Here we demonstrate that impaired actin polymerization results... 
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Protein-Tyrosine Kinases - metabolism | Humans | Actins - metabolism | Lymphocyte Function-Associated Antigen-1 - metabolism | Thalidomide - pharmacology | Lymphocyte Culture Test, Mixed | CD4-Positive T-Lymphocytes - immunology | Thalidomide - analogs & derivatives | Lymphocyte Activation - immunology | T-Lymphocytes - metabolism | T-Lymphocytes - drug effects | CD8-Positive T-Lymphocytes - metabolism | Leukemia, Lymphocytic, Chronic, B-Cell - blood | Antineoplastic Agents - pharmacology | Microfilament Proteins - metabolism | Leukemia, Lymphocytic, Chronic, B-Cell - immunology | Interleukin-2 - metabolism | T-Lymphocytes, Cytotoxic - immunology | Receptors, Antigen, T-Cell - metabolism | CD4-Positive T-Lymphocytes - metabolism | Mice, Transgenic | Proto-Oncogene Proteins - genetics | Lymphocyte Specific Protein Tyrosine Kinase p56(lck) - metabolism | Superantigens - immunology | Antigen Presentation - immunology | Mice, Inbred Strains | B-Lymphocytes - drug effects | Animals | B-Lymphocytes - immunology | CD8-Positive T-Lymphocytes - drug effects | T-Lymphocytes - immunology | Antigen Presentation - drug effects | Mice | CD8-Positive T-Lymphocytes - immunology | CD4-Positive T-Lymphocytes - drug effects | Immunologic Factors - pharmacology | Polymerization | Chronic lymphocytic leukemia | T cells | Muscle proteins | Tumors
Journal Article
Cancer research (Chicago, Ill.), ISSN 1538-7445, 2011, Volume 71, Issue 4, pp. 1263 - 1271
The tumor microenvironment includes a complex network of immune T-cell subpopulations. In this study, we systematically analyzed the balance between cytotoxic... 
Life Sciences & Biomedicine | Oncology | Science & Technology | Th1 Cells - pathology | Th1 Cells - physiology | Prognosis | Th2 Cells - physiology | Tissue Array Analysis | Colorectal Neoplasms - genetics | Humans | Gene Expression Regulation, Neoplastic | Carcinoma - mortality | Gene Expression Profiling | Th2 Cells - immunology | Th1 Cells - immunology | Colorectal Neoplasms - diagnosis | Lymphocytes, Tumor-Infiltrating - physiology | T-Lymphocytes, Cytotoxic - pathology | Th1 Cells - metabolism | Th17 Cells - metabolism | Forkhead Transcription Factors - metabolism | Microarray Analysis | T-Lymphocytes, Helper-Inducer - immunology | Lymphocytes, Tumor-Infiltrating - metabolism | T-Lymphocytes, Helper-Inducer - pathology | Interleukin-4 - genetics | Th2 Cells - pathology | Th17 Cells - pathology | Colorectal Neoplasms - mortality | T-Lymphocytes, Cytotoxic - immunology | Th17 Cells - physiology | T-Lymphocytes, Helper-Inducer - metabolism | Carcinoma - immunology | Interleukin-4 - metabolism | Carcinoma - diagnosis | Forkhead Transcription Factors - genetics | Th2 Cells - metabolism | T-Lymphocytes, Cytotoxic - physiology | T-Lymphocytes, Helper-Inducer - physiology | Colorectal Neoplasms - immunology | Lymphocytes, Tumor-Infiltrating - pathology | T-Lymphocytes, Cytotoxic - metabolism | Survival Analysis | Th17 Cells - immunology | Carcinoma - genetics | Cohort Studies | Lymphocytes, Tumor-Infiltrating - immunology
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2011, Volume 332, Issue 6030, pp. 687 - 696
Flow cytometry is an essential tool for dissecting the functional complexity of hematopoiesis. We used single-cell "mass cytometry" to examine healthy human... 
T lymphocytes | Cytometry | Phosphorylation | RESEARCH ARTICLE | B lymphocytes | Stem cells | Cell lines | Bone marrow | Bone marrow cells | Cells | Hematopoietic stem cells | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Lanthanoid Series Elements | Leukocytes, Mononuclear - metabolism | Flow Cytometry - methods | Humans | Antibodies | Lymphocyte Subsets - immunology | Lymphocyte Subsets - metabolism | T-Lymphocytes - metabolism | Hematopoiesis | Single-Cell Analysis - methods | T-Lymphocytes - drug effects | Bone Marrow Cells - immunology | Leukocytes, Mononuclear - immunology | Mass Spectrometry | Bone Marrow Cells - drug effects | B-Lymphocytes - metabolism | Dasatinib | Leukocytes, Mononuclear - drug effects | Cytokines - metabolism | Bone Marrow Cells - cytology | Lymphocyte Activation | Lymphocyte Subsets - drug effects | Immunophenotyping | Pyrimidines - pharmacology | Transition Elements | B-Lymphocytes - drug effects | Algorithms | B-Lymphocytes - immunology | Signal Transduction - drug effects | T-Lymphocytes - immunology | Protein Kinase Inhibitors - pharmacology | Thiazoles - pharmacology | Antigens, Surface - analysis | Bone Marrow Cells - metabolism | Protein-Tyrosine Kinases - antagonists & inhibitors | Evaluation | Flow cytometry | Immune response | Research | Immunopharmacology | Methods
Journal Article
Clinical Immunology, ISSN 1521-6616, 2010, Volume 138, Issue 1, pp. 85 - 96
Abstract Cytotoxic T Lymphocyte Antigen 4 (CTLA4) blockade has shown antitumor activity against common cancers. However, the exact mechanism of immune... 
Allergy and Immunology | Tremelimumab | T effector cells | CTLA4 | Immune regulation | T regulatory cells | Life Sciences & Biomedicine | Immunology | Science & Technology | T-Lymphocyte Subsets - immunology | CD8-Positive T-Lymphocytes - cytology | Leukocytes, Mononuclear - metabolism | T-Lymphocytes, Regulatory - metabolism | T-Lymphocyte Subsets - cytology | Cell Count | Humans | Antibodies, Monoclonal - therapeutic use | Interferon-gamma - metabolism | T-Lymphocytes, Regulatory - immunology | CD4-Positive T-Lymphocytes - immunology | Lymphocyte Activation - immunology | Immunity, Cellular - drug effects | Forkhead Transcription Factors - metabolism | Immune Tolerance - immunology | T-Lymphocyte Subsets - drug effects | T-Lymphocytes - drug effects | Leukocytes, Mononuclear - immunology | T-Lymphocytes, Regulatory - cytology | CD8-Positive T-Lymphocytes - metabolism | Membrane Glycoproteins - immunology | Immune Tolerance - drug effects | Interleukin-2 - metabolism | Leukocytes, Mononuclear - drug effects | Carcinoembryonic Antigen - immunology | Antibodies, Monoclonal - pharmacology | CD4-Positive T-Lymphocytes - cytology | CD4-Positive T-Lymphocytes - metabolism | Neoplasms - drug therapy | Immunity, Cellular - immunology | T-Lymphocytes, Regulatory - drug effects | Interleukin-2 Receptor alpha Subunit - metabolism | T-Lymphocytes - cytology | Lymphocyte Activation - drug effects | Neoplasms - immunology | T-Lymphocyte Subsets - metabolism | CD8-Positive T-Lymphocytes - drug effects | Leukocytes, Mononuclear - cytology | T-Lymphocytes - immunology | Cell Proliferation - drug effects | CD8-Positive T-Lymphocytes - immunology | CD4-Positive T-Lymphocytes - drug effects | T cells | Tumor antigens | Immune response
Journal Article
Stem cells (Dayton, Ohio), ISSN 1066-5099, 01/2008, Volume 26, Issue 1, pp. 212 - 222
Adult bone marrow‐derived mesenchymal stem cells (MSCs) are multipotent cells that are the subject of intense investigation in regenerative medicine. In... 
Immunosuppression | Regulatory T cells | Human leukocyte antigen‐G | Mesenchymal stem cells | Interleukin‐10 | Interleukin-10 | Human leukocyte antigen-G | T-Lymphocyte Subsets - immunology | T-Lymphocytes, Regulatory - metabolism | Humans | Adult Stem Cells - immunology | Lymphocyte Culture Test, Mixed | Mesenchymal Stromal Cells - immunology | T-Lymphocytes, Regulatory - immunology | Histocompatibility Antigens Class I - metabolism | Mesenchymal Stromal Cells - cytology | Flow Cytometry | Forkhead Transcription Factors - metabolism | Bone Marrow Cells - immunology | Killer Cells, Natural - immunology | T-Lymphocytes, Cytotoxic - immunology | Interferon-gamma | Adult Stem Cells - cytology | Enzyme-Linked Immunosorbent Assay | Bone Marrow Cells - cytology | Cell Communication | Mesenchymal Stromal Cells - metabolism | HLA-G Antigens | HLA Antigens - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Microscopy, Confocal | Adult Stem Cells - metabolism | Interleukin-2 Receptor alpha Subunit - metabolism | T-Lymphocytes, Cytotoxic - metabolism | T-Lymphocyte Subsets - metabolism | Killer Cells, Natural - metabolism | Bone Marrow Cells - metabolism | CD4 Antigens - metabolism | T-Lymphocyte Subsets | Adult Stem Cells | Interleukin-2 Receptor alpha Subunit | Killer Cells, Natural | Antigens, CD4 | Histocompatibility Antigens Class I | T-Lymphocytes, Cytotoxic | Mesenchymal Stem Cells | Life Sciences | Bone Marrow Cells | Immunology | T-Lymphocytes, Regulatory | HLA Antigens | Forkhead Transcription Factors
Journal Article
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