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Journal of Clinical Investigation, ISSN 0021-9738, 03/2014, Volume 124, Issue 3, pp. 1320 - 1328
Journal Article
Journal Article
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 03/2017, Volume 61, Issue 3
As new pathogenic viruses continue to emerge, it is paramount to have intervention strategies that target a common denominator in these pathogens. The fusion... 
Envelope protein | Antiviral | Zika virus | Virus entry | Chikungunya virus | Resistant mutant | LYSOSOMAL FUNCTION | envelope protein | MICROBIOLOGY | SEMLIKI-FOREST-VIRUS | chikungunya virus | CHLOROQUINE | FULL-LENGTH CDNA | IN-VITRO | antiviral | virus entry | PHARMACOLOGY & PHARMACY | INFECTION | resistant mutant | MUTATIONS | CELL ENTRY | ANTIVIRALS | Zika Virus - genetics | Chikungunya virus - genetics | Membrane Glycoproteins - metabolism | Epithelial Cells - drug effects | Humans | Yellow fever virus - growth & development | Semliki forest virus - growth & development | Virus Internalization - drug effects | Endosomes - metabolism | Proto-Oncogene Proteins c-bcl-2 - metabolism | Lysosomes - metabolism | West Nile virus - genetics | Hydrogen-Ion Concentration - drug effects | Endosomes - drug effects | Viral Envelope Proteins - metabolism | Cell Membrane - drug effects | Hepatocytes - drug effects | Membrane Fusion - drug effects | Lysosomes - drug effects | Cell Line | Virus Replication - drug effects | Antiviral Agents - pharmacology | Cricetinae | Gene Expression | Viral Envelope Proteins - genetics | Zika Virus - growth & development | West Nile virus - growth & development | Zika Virus - drug effects | West Nile virus - drug effects | Chikungunya virus - growth & development | Membrane Glycoproteins - genetics | Chikungunya virus - drug effects | Drug Resistance, Viral - genetics | Pyrroles - pharmacology | Yellow fever virus - drug effects | Animals | Semliki forest virus - genetics | Neutral Red - metabolism | Epithelial Cells - virology | Semliki forest virus - drug effects | Hepatocytes - virology | Cell Membrane - virology | Mutation | Proto-Oncogene Proteins c-bcl-2 - genetics | Yellow fever virus - genetics | Index Medicus
Journal Article
Autophagy, ISSN 1554-8627, 03/2015, Volume 11, Issue 3, pp. 560 - 572
The lack of a rapid and quantitative autophagy assay has substantially hindered the development and implementation of autophagy-targeting therapies for a... 
RNA interference screen | GFP, green fluorescent protein | MTOR, mechanistic target of rapamycin | autophagy | autophagy response | RNAi, RNA interference | Cyto-ID | FBS, fetal bovine serum | LAMP1, lysosomal-associated membrane protein 1 | MAP3K6, mitogen-activated protein kinase kinase kinase 6 | shRNA, short-hairpin RNA | RAB5A, member RAS oncogene family | spectrophotometric assay | 3-MA, 3-methyladenine | SQSTM1, sequestosome 1 | MDC, monodansylcadaverine | NS, nonsilencing | WNK2, WNK lysine deficient protein kinase 2 | mRFP, monomeric red fluorescent protein | small molecule screen | autophagy flux | MAP1LC3B/LC3B, microtubule-associated protein 1 light chain 3 beta | Utophagy | Spectrophotometric assay | Autophagy flux | Small molecule screen | Autophagy response | member RAS oncogene family | RNA interference | LC3B | sequestosome 1 | mechanistic target of rapamycin | MDC | monodansylcadaverine | CELL BIOLOGY | GFP | MAP1LC3B | LAMP1 | shRNA | FBS | lysosomal-associated membrane protein 1 | MAP3K6 | LC3 | SIRNA SCREEN | CELLS | RNAi | WNK lysine deficient protein kinase 2 | MARKER | microtubule-associated protein 1 light chain 3 beta | mitogen-activated protein kinase kinase kinase 6 | nonsilencing | CHLOROQUINE | green fluorescent protein | MTOR | short-hairpin RNA | fetal bovine serum | WNK2 | DISEASE | 3-MA | monomeric red fluorescent protein | mRFP | RAB5A | SQSTM1 | 3-methyladenine | Fluorescent Dyes - chemistry | Neoplasm Transplantation | Spectrometry, Fluorescence - methods | Dactinomycin - chemistry | Lysosomes - chemistry | Cell Survival | Humans | Mice, Inbred C57BL | Leukemia - metabolism | MAP Kinase Kinase Kinases - metabolism | Gene Expression Regulation, Leukemic | Mice, SCID | Autophagy | Imatinib Mesylate - chemistry | Animals | RNA Interference | Chloroquine - chemistry | HEK293 Cells | K562 Cells | Endosomes - chemistry | Mice | HeLa Cells | Microscopy, Fluorescence | Protein-Serine-Threonine Kinases - metabolism | Index Medicus
Journal Article
Traffic, ISSN 1398-9219, 04/2018, Volume 19, Issue 4, pp. 273 - 284
Macrophage‐mediated phagocytosis plays an important role in the clearance of cancer cells following opsonization by therapeutic antibodies. We have observed... 
phagosome | macrophages | antibodies | vacuole | lysosome | ACTIVATION | TFEB | MATURATION | MEDIATED PHAGOCYTOSIS | CANCER | LYSOSOMAL BIOGENESIS | CELL BIOLOGY | MHC CLASS-I | AMINO-ACIDS | CROSS-PRESENTATION | Viral antibodies | Analysis | Therapeutics | Antibodies | Macrophages | Tumors | Homeopathy | Materia medica and therapeutics | TOR protein | Tumor cells | Opsonization | ErbB-2 protein | Phagocytosis | Trastuzumab | Cancer | Index Medicus | Original
Journal Article