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Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2009, Volume 603, Issue 1, pp. 62 - 72
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 06/2018, Volume 152, pp. 201 - 210
Label-free cellular assays using a biosensor provide new opportunities for studying G protein-coupled receptor (GPCR) signaling. As opposed to conventional... 
Impedance | Label-free | Inverse agonism | Biosensor | Constitutive activity | mGlu2 receptor | mGlu | receptor | POSITIVE ALLOSTERIC MODULATOR | DEPRESSION | ACTIVATION | FREE TECHNOLOGY | RADIOLIGAND | DRUG DISCOVERY | mGlu receptor | POTENT | PROTEIN-COUPLED RECEPTOR | MGLU(2/3) RECEPTORS | PHARMACOLOGY & PHARMACY | MGLU2 RECEPTOR | Schizophrenia | Drug discovery | G proteins | Glutamate | Detectors | Membrane proteins
Journal Article
Journal of Nuclear Medicine, ISSN 0161-5505, 03/2015, Volume 56, Issue 3, pp. 489 - 492
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2004, Volume 498, Issue 1, pp. 153 - 156
We examined the potential anxiolytic-like activity of (−)- -phenyl-7-(hydroxyimino) cyclopropa[ ]chromen-1 -carboxamide (PHCCC), an allosteric modulator of... 
Allosteric mGlu 4 receptor modulator | Anxiety | Amygdala | mGlu 1 receptor antagonist | mGlu | Allosteric mGlu | receptor antagonist | receptor modulator
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 2011, Volume 21, Issue 23, pp. 6955 - 6959
Herein we report the discovery and SAR of a novel antagonist of metabotropic glutamate receptor 4 (mGlu ). The antagonist was discovered via a molecular switch... 
Metabotropic glutamate receptor 4 | Antagonist | Molecular switch | mGlu 4 | mGlu
Journal Article
Bioorganic and Medicinal Chemistry, ISSN 0968-0896, 2017, Volume 25, Issue 2, pp. 496 - 513
Triazolopyridine ethers with mGlu positive allosteric modulator (PAM) activity are disclosed. The synthesis, in vitro activity, and metabolic stability data... 
Metabotropic glutamate receptors | mGlu | Triazolopyridine | Schizophrenia
Journal Article
Neuropharmacology, ISSN 0028-3908, 03/2017, Volume 115, pp. 100 - 114
Metabotropic glutamate (mGlu ) receptors are of considerable interest owing to their role in modulating glutamate transmission via presynaptic, postsynaptic... 
Metabotropic glutamate receptors | mGlu3 | LY3020371 | mGlu2 | mGlu
Journal Article