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Journal Article
Journal Article
ACS CHEMICAL NEUROSCIENCE, ISSN 1948-7193, 09/2018, Volume 9, Issue 9, pp. 2210 - 2217
Rett syndrome and MECP2 Duplication syndrome are neurodevelopmental disorders attributed to loss-of-function mutations in, or duplication of, the gene encoding... 
negative allosteric modulator | MeCP2 | CHEMISTRY, MEDICINAL | RETT-SYNDROME | AMYGDALA PLASTICITY | TERMINALS | BEHAVIOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | SYNAPTIC-TRANSMISSION | MECP2 Duplication syndrome | NEUROSCIENCES | mGlu | OVEREXPRESSION | GLUTAMATE-RECEPTOR 7 | Rett syndrome | MGLUR7 | RAT HIPPOCAMPUS | ADX71743 | MUTATIONS
Journal Article
Pain, ISSN 0304-3959, 12/2009, Volume 147, Issue 1-3, pp. 175 - 186
Metabotropic glutamate (mGlu) receptors, which are present on neurons and glial cells, have been shown to play a role in neuropathic pain. The present study... 
Pentoxifylline | Minocycline | mGlu receptors | Glia | Neuropathic pain | mGlu receptor ligands | 2-METHYL-6-(PHENYLETHYNYL)-PYRIDINE MPEP | METABOTROPIC GLUTAMATE RECEPTORS | NEUROSCIENCES | RAT MODEL | CLINICAL NEUROLOGY | SPINAL DORSAL-HORN | INDUCED PERIPHERAL INFLAMMATION | TUMOR-NECROSIS-FACTOR | PROINFLAMMATORY CYTOKINE EXPRESSION | IN-VIVO | ATTENUATES MECHANICAL ALLODYNIA | ANESTHESIOLOGY | SCIATIC-NERVE LIGATION | Glial Fibrillary Acidic Protein - genetics | Spinal Cord - drug effects | Spinal Cord - metabolism | Minocycline - pharmacology | Male | Receptors, Metabotropic Glutamate - metabolism | Glial Fibrillary Acidic Protein - metabolism | RNA, Messenger - metabolism | Complement C1q - metabolism | Amino Acids - pharmacology | Sciatica - drug therapy | CD11b Antigen - genetics | Receptors, Metabotropic Glutamate - genetics | Pain Threshold - drug effects | Pentoxifylline - pharmacology | Disease Models, Animal | Drug Administration Schedule | Hyperalgesia - metabolism | Enzyme Inhibitors - pharmacology | Sciatica - etiology | Sciatica - complications | Excitatory Amino Acid Antagonists - pharmacology | Glial Fibrillary Acidic Protein - antagonists & inhibitors | Sciatica - metabolism | Complement C1q - genetics | Functional Laterality | Gene Expression Regulation - drug effects | Bridged Bicyclo Compounds, Heterocyclic - pharmacology | Pain Measurement - methods | Animals | Analysis of Variance | Complement C1q - antagonists & inhibitors | Hyperalgesia - etiology | Benzhydryl Compounds - pharmacology | Mice | Pyridines - pharmacology | CD11b Antigen - metabolism | Receptors, Metabotropic Glutamate - agonists | Receptors, Metabotropic Glutamate - antagonists & inhibitors | Messenger RNA | Analgesics | Glutamate | Intermediate filament proteins | Analysis
Journal Article
Journal Article
Neuropharmacology, ISSN 0028-3908, 03/2013, Volume 66, pp. 187 - 195
Metabotropic glutamate receptors (mGlus) are 7 Transmembrane Spanning Receptors (7TMs) that are differentially expressed throughout the brain and modulate... 
Metabotropic glutamate receptor (mGlu) | Parkinson's disease | Haloperidol | Reserpine | Catalepsy | 6-Hydroxydopamine | POSITIVE ALLOSTERIC MODULATOR | DOPA-INDUCED DYSKINESIA | RAT | MESSENGER-RNA EXPRESSION | BASAL GANGLIA | AKINESIA | SPINAL-CORD | OCCUPANCY | NEUROSCIENCES | ANTIPSYCHOTICS | ANIMAL-MODELS | PHARMACOLOGY & PHARMACY | Glycine - analogs & derivatives | Glycine - therapeutic use | Catalepsy - drug therapy | Benzoates - therapeutic use | Excitatory Amino Acid Agonists - therapeutic use | Injections, Intraventricular | Receptors, Metabotropic Glutamate - physiology | Catalepsy - metabolism | Male | Aminobutyrates - pharmacology | Receptors, Dopamine D2 - metabolism | Aminobutyrates - therapeutic use | Dose-Response Relationship, Drug | Parkinsonian Disorders - metabolism | Forelimb - physiopathology | Neostriatum - drug effects | Time Factors | Dyskinesia, Drug-Induced - drug therapy | Parkinsonian Disorders - drug therapy | Catalepsy - chemically induced | Neostriatum - metabolism | Aminobutyrates - administration & dosage | Forelimb - drug effects | Dopamine - metabolism | Glycine - administration & dosage | Disease Models, Animal | Parkinsonian Disorders - physiopathology | Rats | Excitatory Amino Acid Agonists - pharmacology | Rats, Sprague-Dawley | Benzoates - administration & dosage | Excitatory Amino Acid Agonists - administration & dosage | Animals | Glycine - pharmacology | Benzoates - pharmacology | Dyskinesia, Drug-Induced - metabolism | Receptors, Metabotropic Glutamate - agonists | Dopamine D2 Receptor Antagonists | Neurosciences | Corticosteroids | Neurons | Amino acids | Glutamate | Dopamine receptors
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 01/2006, Volume 96, Issue 1, pp. 179 - 194
Previous studies have shown that brief application of group I metabotropic glutamate receptor (mGluR) agonist (S)‐3, 5‐dihydroxyphenylglycine (DHPG) to... 
long‐term depression | hippocampus | metabotropic glutamate receptor | protein tyrosine phosphatase | endocytosis | 5‐dihydroxyphenylglycine | (S)‐3 | long-term depression | BIOCHEMISTRY & MOLECULAR BIOLOGY | MGLU RECEPTORS | AMPA RECEPTOR | D-ASPARTATE RECEPTOR | SYNAPTIC PLASTICITY | AREA CA1 | NEUROSCIENCES | 5-dihydroxyphenylglycine | RAPID REDISTRIBUTION | GLUTAMATE-RECEPTOR ACTIVATION | RAT HIPPOCAMPUS | DHPG-INDUCED LTD | KINASE ACTIVATION | (S)-3 | Glycine - analogs & derivatives | Immunoprecipitation | 2-Amino-5-phosphonovalerate - pharmacology | Depression, Chemical | Electrophysiology | Neuronal Plasticity - drug effects | Receptors, Metabotropic Glutamate - physiology | Male | Hippocampus - drug effects | Receptor, Metabotropic Glutamate 5 | Synapses - drug effects | Methoxyhydroxyphenylglycol - antagonists & inhibitors | Rats | Excitatory Amino Acid Antagonists - pharmacology | Rats, Sprague-Dawley | Blotting, Western | Methoxyhydroxyphenylglycol - analogs & derivatives | Methoxyhydroxyphenylglycol - pharmacology | Animals | Glycine - pharmacology | Signal Transduction - drug effects | Hippocampus - physiology | In Vitro Techniques | Enzyme Activation - physiology | Receptors, AMPA - drug effects | Protein Tyrosine Phosphatases - physiology | Proteins | Depression, Mental | Neurology | Biochemistry | Inhibitor drugs | Gene expression
Journal Article