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Journal of Molecular Biology, ISSN 0022-2836, 2002, Volume 319, Issue 3, pp. 615 - 635
mRNA 5-cap recognition by the eukaryotic translation initiation factor eIF4E has been exhaustively characterized with the aid of a novel fluorometric,... 
translation | structure–activity relationship | eIF4E | mRNA 5′ cap | fluorescence | Fluorescence | Translation | Structure-activity relationship | FACTOR EIF-4E | mRNA 5 ' cap | THERMODYNAMIC ORIGINS | OSMOTIC-STRESS | MESSENGER-RNA CAP | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | INITIATION-FACTOR 4E | (S/T)P SITES | DEPENDENT TRANSLATION INITIATION | 5'-CAP ANALOGS | RETICULOCYTE LYSATE | structure-activity relationship | Phosphorylation | Molecular Sequence Data | Crystallography, X-Ray | Structure-Activity Relationship | Phosphoproteins - metabolism | RNA Caps - metabolism | Eukaryotic Initiation Factor-4E | Phosphoproteins - chemistry | Peptide Initiation Factors - chemistry | Thermodynamics | Osmolar Concentration | RNA Caps - chemistry | Carrier Proteins - chemistry | RNA Cap Analogs - metabolism | Protein Structure, Tertiary | Amino Acid Sequence | Peptide Fragments - metabolism | RNA-Binding Proteins - chemistry | Electrolytes - metabolism | Models, Molecular | Static Electricity | Peptide Fragments - chemical synthesis | Peptide Initiation Factors - metabolism | Peptide Fragments - chemistry | Phosphates - metabolism | Animals | Carrier Proteins - metabolism | Eukaryotic Initiation Factor-4G | Hydrogen Bonding | RNA Cap Analogs - chemistry | Protein Binding | Mice | RNA Cap-Binding Proteins | Methylation | RNA-Binding Proteins - metabolism
Journal Article
Analytical Biochemistry, ISSN 0003-2697, 09/2015, Volume 484, pp. 72 - 74
Eukaryotic messenger RNAs (mRNAs) are generally enriched using oligo(dT) selection. However, a significant fraction of mRNAs contain either short or no... 
mRNA | Biotinylation | Purification | 5′ Cap | CHEMISTRY, ANALYTICAL | ACID | CAGE | 5 ' Cap | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOCHEMICAL RESEARCH METHODS | ANALYSIS GENE-EXPRESSION | IDENTIFICATION | POLY(A) TAIL | Polynucleotide Adenylyltransferase - metabolism | RNA Caps - chemistry | Eukaryota | RNA Caps - metabolism
Journal Article
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, ISSN 0962-8436, 12/2018, Volume 373, Issue 1762, p. 20180167
The 5'-terminus of eukaryotic mRNAs comprises a 7-methylguanosine cap linked to the first transcribed nucleotide via a 5'-5' triphosphate bond. This cap... 
RECOGNITION | ANALOGS | biotin | RNA degradation | BINDING PROTEIN | TRANSLATION | RESISTANT | ENZYME | mRNA cap | 5'-CAP STRUCTURE | BIOLOGY | GENE-EXPRESSION | EIF4E | DCPS
Journal Article
Journal Article
Bioconjugate Chemistry, ISSN 1043-1802, 07/2017, Volume 28, Issue 7, p. 1978
mRNA is a template for protein biosynthesis, and consequently mRNA transport, translation, and turnover are key elements in the overall regulation of gene... 
Post-transcription | Transcription factors | Transcription | mRNA turnover | Fluorescence | Labelling | Protein biosynthesis | Biosynthesis | Marking | Detonators | Ribonucleic acid--RNA | Gene expression | Cells | Analogs | Chemistry | RNA transport | Decay | Tagging | In vivo methods and tests | Localization | In vitro methods and tests
Journal Article
Philosophical transactions of the Royal Society of London. Series B, Biological sciences, ISSN 0962-8436, 12/2018, Volume 373, Issue 1762
Journal Article
FEBS Letters, ISSN 0014-5793, 12/2013, Volume 587, Issue 24, pp. 3928 - 3934
Initiation is the rate-limiting step during mRNA 5′ cap-dependent translation, and thus a target of a strict control in the eukaryotic cell. It is shown here... 
Fluorescence | eIF4E | 4E-BP1 | Analytical ultracentrifugation | mRNA 5′cap | Translation initiation | tris (2-carboxyethyl) phosphine HCl | m7GTP | 4E binding protein 1 | eukaryotic initiation factor 4E | TFA | trifluoroacetic acid | SPR | surface plasmon resonance | 7-methylguanosine 5′-triphosphate | dialysis buffer | TCEP | STRUCTURAL INSIGHTS | mRNA 5 ' cap | ANALOGS | BIOCHEMISTRY & MOLECULAR BIOLOGY | BINDING-PROTEINS | ULTRACENTRIFUGATION | CELL BIOLOGY | SEDIMENTATION COEFFICIENT DISTRIBUTIONS | BIOPHYSICS | FACTOR 4E | TERMINAL FLEXIBLE REGION | SURFACE-PLASMON RESONANCE | 5'-CAP | 4E-BINDING PROTEIN | Adaptor Proteins, Signal Transducing - chemistry | Eukaryotic Initiation Factors - chemistry | Eukaryotic Initiation Factors - metabolism | Fractionation, Field Flow | Humans | Eukaryotic Initiation Factor-4E - metabolism | Ultracentrifugation | Phosphoproteins - metabolism | RNA Caps - metabolism | RNA, Messenger - metabolism | Phosphoproteins - chemistry | Multiprotein Complexes - metabolism | Eukaryotic Initiation Factor-4E - chemistry | Multiprotein Complexes - chemistry | Models, Biological | Protein Multimerization - physiology | Peptide Chain Initiation, Translational - physiology | Protein Conformation | RNA, Messenger - chemistry | Adaptor Proteins, Signal Transducing - metabolism | Protein Binding - physiology | Genetic translation | Messenger RNA
Journal Article
EMBO JOURNAL, ISSN 0261-4189, 10/2001, Volume 20, Issue 19, pp. 5491 - 5502
mRNA silencing and storage play an important role in gene expression under diverse circumstances, such as throughout early metazoan development and in response... 
Y-BOX PROTEINS | ACID BINDING-PROTEINS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | POLY(A)-BINDING PROTEIN | MESSENGER-RNA STABILITY | CELL BIOLOGY | cap structure | IN-VITRO | translation | COLD-SHOCK DOMAIN | SECONDARY STRUCTURE | cold shock domain | messenger ribonucleoproteins | TRANSCRIPTION FACTOR | mRNA stability | RABBIT RETICULOCYTES
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 09/2011, Volume 21, Issue 18, pp. 5457 - 5459
Photoresponsive 5′-caps that can be reversibly – isomerized by light irradiation were developed for the reversible photoregulation of gene expression. The... 
Translation | mRNA | Photoisomerization | Protein | Photoregulation | ZEBRAFISH EMBRYOS | CELLS | ACTIVATION | CHEMISTRY, MEDICINAL | LIGHT | CHEMISTRY, ORGANIC | MESSENGER-RNA | CAP ANALOGS | Gene Expression | Stereoisomerism | Light | Models, Molecular | RNA Caps - chemistry | 5' Untranslated Regions - genetics | RNA Caps - genetics | Gene expression | Messenger RNA
Journal Article