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1. Full Text Volanesorsen and Triglyceride Levels in Familial Chylomicronemia Syndrome
by Witztum, Joseph L and Gaudet, Daniel and Freedman, Steven D and Alexander, Veronica J and Digenio, Andres and Williams, Karren R and Yang, Qingqing and Hughes, Steven G and Geary, Richard S and Arca, Marcello and Stroes, Erik S.G and Bergeron, Jean and Soran, Handrean and Civeira, Fernando and Hemphill, Linda and Tsimikas, Sotirios and Blom, Dirk J and O’Dea, Louis and Bruckert, Eric
The New England journal of medicine, ISSN 0028-4793, 08/2019, Volume 381, Issue 6, pp. 531 - 542
Double-Blind Method | Oligonucleotides/administration & dosage | Thrombocytopenia/chemically induced | Humans | Middle Aged | RNA, Messenger/antagonists & inhibitors | Hyperlipoproteinemia Type I/blood | Male | Injections, Subcutaneous/adverse effects | Young Adult | Platelet Count | Analysis of Variance | Triglycerides/blood | Adult | Female | Aged | Apolipoprotein C-III/antagonists & inhibitors | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Apolipoprotein C-III - antagonists & inhibitors | Oligonucleotides - therapeutic use | Hyperlipoproteinemia Type I - blood | Apolipoprotein C-III - blood | Oligonucleotides - adverse effects | Apolipoprotein C-III - genetics | Injections, Subcutaneous - adverse effects | Thrombocytopenia - chemically induced | RNA, Messenger - antagonists & inhibitors | Triglycerides - blood | Hyperlipoproteinemia Type I - drug therapy | Oligonucleotides - administration & dosage | Usage | Safety and security measures | Genetic disorders | Chylomicrons | Drug therapy | Health aspects | Antilipemic agents | Thrombocytopenia | Fasting | Statistical analysis | Laboratories | Pancreatitis | Clinical trials | Antisense therapy | mRNA | Lipoprotein lipase | Injection | Lipase | Apolipoproteins | Fatty acids | Lipoproteins | Apolipoprotein C-III | Mutation | Platelets | Drug dosages | Pharmaceuticals | Index Medicus | Abridged Index Medicus | Life Sciences
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2. Full Text Homocysteine modulates 5‐lipoxygenase expression level via DNA methylation
by Li, Jian‐Guo and Barrero, Carlos and Gupta, Sapna and Kruger, Warren D and Merali, Salim and Praticò, Domenico
Aging cell, ISSN 1474-9718, 04/2017, Volume 16, Issue 2, pp. 273 - 280
homocysteine | S‐adenosylmethionine | Alzheimer's disease | methylation | amyloid beta | 5‐lipoxygenase | 5-lipoxygenase | S-adenosylmethionine | Life Sciences & Biomedicine | Geriatrics & Gerontology | Science & Technology | Cell Biology | Hyperhomocysteinemia - enzymology | Transcription, Genetic - drug effects | Arachidonate 5-Lipoxygenase - metabolism | Humans | RNA, Messenger - genetics | Brain - enzymology | Male | DNA Methylation - genetics | RNA, Messenger - metabolism | Brain - drug effects | Animals | Diet | Homocysteine - pharmacology | Amyloid beta-Peptides - metabolism | Hyperhomocysteinemia - genetics | Protein Biosynthesis - drug effects | Mice | Neurons - metabolism | Neurons - drug effects | DNA Methylation - drug effects | Genetic research | Methylation | Homocysteine | DNA | DNA methylation | Neurosciences | Alzheimers disease | Deoxyribonucleic acid--DNA | Adenosylmethionine | Neurodegenerative diseases | Nervous system | mRNA | S-Adenosylmethionine | Arachidonate 5-lipoxygenase | β-Amyloid | Lipoxygenase | Index Medicus | Original
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3. Full Text Cell-cycle regulation accounts for variability in Ki-67 expression levels
by Sobecki, Michal and Mrouj, Karim and Colinge, Jacques and Gerbe, François and Jay, Philippe and Krasinska, Liliana and Dulic, Vjekoslav and Fisher, Daniel
Cancer research (Chicago, Ill.), ISSN 0008-5472, 05/2017, Volume 77, Issue 10, pp. 2722 - 2734
Life Sciences & Biomedicine | Oncology | Science & Technology | Immunohistochemistry | Cell Cycle - genetics | Cell Proliferation - genetics | Gene Expression | Intestinal Mucosa - metabolism | Humans | Gene Expression Regulation, Neoplastic | Cell Survival - genetics | Ki-67 Antigen - metabolism | Gene Expression Profiling | Gene Regulatory Networks | Mice, Knockout | Xenograft Model Antitumor Assays | Animals | Ki-67 Antigen - genetics | Biomarkers | Cell Line, Tumor | Female | Antineoplastic Agents - pharmacology | Cell Proliferation - drug effects | Mice | Cluster Analysis | Intestinal Mucosa - pathology | Cell proliferation | Regulations | Mitosis | Variability | mRNA | Tumor cell lines | Cyclin-dependent kinase 4 | Cell growth | Histopathology | Inhibitors | Intestine | Rodents | Cell cycle | Colon | Inhibition | Cancer | Tumors | Index Medicus | Life Sciences | Biochemistry, Molecular Biology
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4. Full Text BRCA1 mRNA levels following a 4-6-week intervention with oral 3,3'-diindolylmethane
by Kotsopoulos, J and Zhang, S and Akbari, M and Salmena, L and Llacuachaqui, M and Zeligs, M and Sun, P and Narod, S.A
British journal of cancer, ISSN 0007-0920, 2014, Volume 111, Issue 7, pp. 1269 - 1274
Life Sciences & Biomedicine | Oncology | Science & Technology | Gynecology. Andrology. Obstetrics | Mammary gland diseases | Biological and medical sciences | Multiple tumors. Solid tumors. Tumors in childhood (general aspects) | Medical sciences | Tumors | Up-Regulation | Gene Expression - drug effects | Administration, Oral | Humans | Middle Aged | RNA, Messenger - genetics | RNA, Messenger - metabolism | Indoles - administration & dosage | Breast Neoplasms - prevention & control | BRCA1 Protein - genetics | Anticarcinogenic Agents - administration & dosage | BRCA1 Protein - metabolism | Adult | Female | Aged | Mutation | Index Medicus | 3,3′-diindolylmethane (DIM) | breast cancer | BRCA1 | Clinical Study | mRNA expression
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5. Full Text TDP-43 regulates its mRNA levels through a negative feedback loop
by Romano, Maurizio and Avendaño-Vázquez, S Eréndira and D'Ambrogio, Andrea and Ule, Jernej and Dhir, Ashish and Baralle, Marco and Tollervey, James and Ayala, Youhna M and De Conti, Laura and Buratti, Emanuele and Baralle, Francisco E
The EMBO journal, ISSN 0261-4189, 01/2011, Volume 30, Issue 2, pp. 277 - 288
neurodegeneration | hnRNP | RNA–protein interaction | 3′ UTR | mRNA stability | 3' UTR | RNA-protein interaction | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Cell Line | Immunoprecipitation | Gene Library | Gene Expression Regulation - genetics | Humans | Molecular Sequence Data | Immunoblotting | DNA-Binding Proteins - genetics | RNA, Messenger - metabolism | Sequence Analysis, DNA | DNA-Binding Proteins - metabolism | Blotting, Northern | RNA Processing, Post-Transcriptional - genetics | RNA Interference | Base Sequence | Plasmids - genetics | Polymerase Chain Reaction | Feedback, Physiological - physiology | Proteins | Mutation | Molecular biology | Feedback | Binding sites | Index Medicus
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6. Full Text PPARγ promotes diabetes‐associated centrosome amplification via increasing the expression of SKA1 directly at the transcriptional level
by Liu, Qin Qin and Wang, Pu and He, Qin Ju and Ma, Ronald and Lee, Shao Chin
Journal of cellular physiology, ISSN 0021-9541, 11/2019, Volume 234, Issue 11, pp. 20694 - 20703
centrosome amplification | transcription, type 2 diabetes | PPARγ | SKA1 | Physiology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Transcription | Diabetes mellitus | mRNA | siRNA | Glucose | Ribonucleic acid--RNA | Palmitic acid | Gene expression | Insulin | Amplification | Organic chemistry | Molecular modelling | Colon cancer | Acids | Diabetes | Colon | Inhibition | Diabetes mellitus (non-insulin dependent) | Binding sites | Index Medicus
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7. Full Text Adenosine methylation in Arabidopsis mRNA is associated with the 3′ end and reduced levels cause developmental defects
by Bodi, Zsuzsanna and Zhong, Silin and Mehra, Surbhi and Song, Jie and Graham, Neil and Li, Hongying and May, Sean and Fray, Rupert George
Frontiers in plant science, ISSN 1664-462X, 03/2012, Volume 3, pp. 48 - 48
IME4 | Post-transcriptional | MT-A70 | METTL3 | mRNA methylation | Life Sciences & Biomedicine | Plant Sciences | Science & Technology | post-transcriptional
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8. Full Text Effects of Low‐Level Laser Irradiation in a Mouse Model of Allergic Rhinitis
by Bae, Jun‐Sang and Kim, Sang Hyub and Kim, Jie Hye and Kim, Eun Hee and Lyu, Lele and Chung, Phil Sang and Mo, Ji‐Hun
Lasers in surgery and medicine, ISSN 0196-8092, 04/2020, Volume 52, Issue 4, pp. 347 - 357
straight | diffusion | nitric oxide | allergic rhinitis | low level laser irradiation | reactive oxygen species | Life Sciences & Biomedicine | Dermatology | Surgery | Science & Technology | Cell culture | Evaluation | Ovalbumin | Reactive oxygen species | Level (quantity) | Rhinitis | Leukocytes (eosinophilic) | Rubbing | Mucosa | Interleukin | Immunoglobulin G | Immunoglobulin E | mRNA | Gene expression | Lymph nodes | Sneezing | Lasers | Nitric oxide | Allergic rhinitis | Nose | Irradiation | Infiltration | Interferon | Diffusion | Index Medicus
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9. Full Text LINC00520 targeting miR‐27b‐3p regulates OSMR expression level to promote acute kidney injury development through the PI3K/AKT signaling pathway
by Tian, Xinghan and Ji, Yongqiang and Liang, Yafeng and Zhang, Jing and Guan, Lina and Wang, Chunting
Journal of cellular physiology, ISSN 0021-9541, 08/2019, Volume 234, Issue 8, pp. 14221 - 14233
acute kidney injury | PI3K‐AKT | miR‐27b‐3p | OSMR | LINC00520 | miR-27b-3p | PI3K-AKT | Physiology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Cell Line | Cell Proliferation - genetics | Acute Kidney Injury - pathology | Gene Expression Regulation - genetics | Humans | Rats | Acute Kidney Injury - genetics | RNA, Long Noncoding - genetics | Signal Transduction - genetics | Gene Knockdown Techniques | Phosphatidylinositol 3-Kinases - genetics | Animals | Oncogene Protein v-akt - genetics | MicroRNAs - genetics | Oncostatin M Receptor beta Subunit - genetics | Proteins | Genetic research | MicroRNA | Analysis | Flow cytometry | Kidneys | Pathogenesis | AKT protein | mRNA | Ribonucleic acid--RNA | 1-Phosphatidylinositol 3-kinase | Signal transduction | Reporter gene | Injury prevention | Reperfusion | Ischemia | miRNA | Apoptosis | Index Medicus
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