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The Journal of biological chemistry, ISSN 0021-9258, 05/2013, Volume 288, Issue 22, pp. 15556 - 15570
Journal Article
Cancer science, ISSN 1347-9032, 03/2018, Volume 109, Issue 3, pp. 688 - 698
Bone marrow mesenchymal stem cells (BMMSC) have been shown to be recruited to the tumor microenvironment and exert a tumor‐promoting effect in a variety of... 
epithelial mesenchymal transition | head and neck cancer | bone marrow mesenchymal stem cells | PI3K/Akt/mTOR | Periostin | Life Sciences & Biomedicine | Oncology | Science & Technology | Neoplasm Transplantation | Up-Regulation | Cell Proliferation | Signal Transduction | TOR Serine-Threonine Kinases - metabolism | Cell Adhesion Molecules | Humans | Gene Expression Regulation, Neoplastic | Culture Media, Conditioned - pharmacology | Phosphatidylinositol 3-Kinases - metabolism | Disease Progression | Head and Neck Neoplasms - metabolism | Neoplasm Metastasis | Animals | Mesenchymal Stem Cells - cytology | Epithelial-Mesenchymal Transition | Cell Line, Tumor | Mice | Neoplasm Staging | Proto-Oncogene Proteins c-akt - metabolism | Mesenchymal Stem Cells - metabolism | Head and neck cancer | Development and progression | Metastasis | Analysis | Stem cells | TOR protein | Cell proliferation | Transformation | Animal models | Mesenchyme | Stem cell transplantation | AKT protein | Kinases | Lymph nodes | Metastases | Ovarian cancer | Cell adhesion & migration | Proteins | Ethics | Signal transduction | Penicillin | Cell cycle | Fibroblasts | Bone marrow | Growth factors | Cytokines | Rapamycin | Breast cancer | Tumorigenicity | Cadherin | 1-Phosphatidylinositol 3-kinase | Molecular modelling | Biomarkers | Head & neck cancer | Laboratory animals | Cell migration | Regulatory proteins | Apoptosis | Tumors | Index Medicus | PI3K | mTOR | Akt | Original
Journal Article
Journal of allergy and clinical immunology, ISSN 0091-6749, 11/2012, Volume 130, Issue 5, pp. 1159 - 1166.e6
.... Objectives Our goal was to investigate a role for mammalian target of rapamycin (mTOR) signaling in the activation of TH 2 and ILC responses and the induction of airway inflammation by IL-33... 
Allergy and Immunology | mammalian target of rapamycin | asthma | innate lymphoid cells | IL-33 | TH2 | rapamycin | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Interleukin-1 Receptor-Like 1 Protein | Class Ia Phosphatidylinositol 3-Kinase - metabolism | Ribosomal Protein S6 Kinases - metabolism | TOR Serine-Threonine Kinases - metabolism | Humans | Immunity, Innate - genetics | Th2 Cells - immunology | Th2 Cells - drug effects | Immunity, Cellular - drug effects | Pneumonia - chemically induced | Pneumonia - immunology | Immunity, Cellular - genetics | Immunity, Innate - drug effects | Interleukin-33 | Interleukin-5 - metabolism | Cells, Cultured | Interleukin-13 - metabolism | Receptors, Interleukin - genetics | Mice, Knockout | Animals | Pneumonia - drug therapy | Interleukins - administration & dosage | Signal Transduction - drug effects | Mice | Mice, Inbred BALB C | Th2 Cells - transplantation | Virus diseases | T cells | Inflammation | Flow cytometry | Cell growth | Phosphorylation | Lungs | Rodents | Kinases | Viral infections | Methods | Index Medicus | Abridged Index Medicus | rpS6, Ribosomal protein S6 | S6K1, Ribosomal protein S6 kinase 1 | TCR, T-cell receptor | 2), Mammalian target of rapamycin (complex 1 | Lin, Lineage-specific marker | ICOS, Inducible costimulator | BAL, Bronchoalveolar lavage | WT, Wild-type | APC, Allophycocyanin | TSLP, Thymic stromal lymphopoietin | mTOR(C1 | PE, Phycoerythrin | PI3K, Phosphoinositide 3-kinase | ILC, Innate lymphoid cell | AHR, Airway hyperresponsiveness | Mechanisms of Allergy and Clinical Immunology
Journal Article
Biochemical journal, ISSN 0264-6021, 07/2009, Volume 421, Issue 1, pp. 29 - 42
mTOR (mammalian target of rapamycin) stimulates cell growth by phosphorylating and promoting activation of AGC... 
Phosphoinositide 3-kinase (PI3K) | Akt/protein kinase B (PKB) | Serum and glucocorticoid protein kinase (SGK) | P70 ribosomal S6 kinase (S6K) | Kinase inhibitor | Cancer | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Cell Line | Humans | Multiprotein Complexes | Morpholines - pharmacology | Transcription Factors - antagonists & inhibitors | Gene Expression Profiling | G1 Phase - drug effects | Pyrimidines - pharmacology | Morpholines - chemistry | Pyrimidines - chemistry | Mechanistic Target of Rapamycin Complex 1 | Gene Expression Regulation - drug effects | Proteins | Transcription Factors - metabolism | Animals | Fibroblasts - drug effects | Cell Proliferation - drug effects | Mice | TOR Serine-Threonine Kinases | Fibroblasts - metabolism | Index Medicus | PI3K, phosphoinositide 3-kinase | PDK, 3-phosphoinositide-dependent protein kinase | AMPK, AMP-activated protein kinase | mTORC, mTOR complex | DTT, dithiothreitol | phosphoinositide 3-kinase (PI3K) | p70 ribosomal S6 kinase (S6K) | SPHK, sphingosine kinase | ERK, extracellular-signal-regulated kinase | RSK, ribosomal S6 kinase | PH domain, pleckstrin homology domain | protein kinase B (PKB) | protein kinase G | NDRG1, N-Myc downstream-regulated gene-1 | IGF, insulin-like growth factor | mTOR, mammalian target of rapamycin | GST, glutathione transferase | SGK, serum and glucocorticoid protein kinase | PKC, protein kinase C | S6K, p70 ribosomal S6 kinase | eIF4E, eukaryotic initiation factor 4E | 4E-BP1, eIF4E-binding protein 1 | protein kinase C family | Akt | PRAS40, proline-rich Akt substrate of 40 kDa | HEK-293 cell, human embryonic kidney 293 cell | kinase inhibitor | MEF, mouse embryonic fibroblast | AGC family, protein kinase A | cancer | serum and glucocorticoid protein kinase (SGK) | MAPK, mitogen-activated protein kinase
Journal Article
Canadian Journal of Physiology and Pharmacology, ISSN 0008-4212, 2019, Volume 97, Issue 12, pp. 1193 - 1203
Mammalian target of rapamycin (mTOR) has been recognized with potential immunomodulatory properties playing an important role in various physiopathological processes including ischemia–reperfusion (I/R) injury... 
rpS6 | inflammation | stress oxydatif–nitrosatif | hindlimb ischemia–reperfusion | mTOR | ischémie–reperfusion de la patte postérieure | oxidative–nitrosative stress | Pharmacology & Pharmacy | Physiology | Life Sciences & Biomedicine | Science & Technology | Biomarkers - metabolism | Gene Expression Regulation, Enzymologic - drug effects | Kidney - drug effects | Kidney - pathology | Rats, Wistar | TOR Serine-Threonine Kinases - metabolism | Rats | Male | Muscle, Skeletal - metabolism | Sirolimus - pharmacology | Inflammation - metabolism | Kidney - metabolism | Animals | Transcription Factor RelA - metabolism | Hindlimb - blood supply | Ribosomal Protein S6 - metabolism | Muscle, Skeletal - drug effects | NF-KappaB Inhibitor alpha - metabolism | Muscle, Skeletal - pathology | Oxidative Stress - drug effects | Reperfusion Injury - metabolism | Nitrosative Stress - drug effects | Oxidases | Phosphates | Ethylenediaminetetraacetic acid | COX-2 inhibitors | Niacinamide | Ischemia | Nitric oxide | Aprotinin | Inflammation | TOR protein | Oxidative stress | Inhibitor drugs | Inflammatory response | Effects | NAD(P)H oxidase | Antioxidants | Signal transduction | Reperfusion | Catalase | Rodents | Peroxidase | Gastrocnemius muscle | Injuries | NF-κB protein | Kidneys | NADPH-diaphorase | Immunomodulation | Organs | Muscles | Adenine | Rapamycin | Ribosomal protein S6 | Pharmacology | Tumor necrosis factor-α | Mammals | Malondialdehyde | Nitric-oxide synthase | Stress | Studies | Signaling | Inhibitors | Nicotinamide adenine dinucleotide | Nitrotyrosine | Nicotinamide | Cyclooxygenase-2 | Index Medicus
Journal Article
Epilepsia (Copenhagen), ISSN 0013-9580, 2017, Volume 58, Issue 8, pp. 1462 - 1472
Journal Article