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Biochemistry and Cell Biology, ISSN 0829-8211, 2019, Volume 97, Issue 1, pp. 58 - 67
The mechanistic target of rapamycin (mTOR) is an evolutionarily conserved serine/threonine kinase that senses and integrates environmental information into... 
mTOR | mTORC2 | mTORC1
Journal Article
Journal of Cell Science, ISSN 0021-9533, 02/2018, Volume 131, Issue 3
Journal Article
International Immunology, ISSN 0953-8178, 2012, Volume 24, Issue 3, pp. 137 - 146
Journal Article
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 03/2018, Volume 58, Issue 3, pp. 378 - 390
Journal Article
Autophagy, ISSN 1554-8627, 04/2019, Volume 15, Issue 4, pp. 742 - 743
WIPI2 contributes to autophagy by recruiting the ATG12-ATG5-ATG16L1 complex to PtdIns3P-rich membranes, which enables the growth and elongation of phagophores.... 
HUWE1 | MTORC1 | WIPI2 | ubiquitination | Autophagy | CELL BIOLOGY
Journal Article
SCIENCE, ISSN 0036-8075, 01/2016, Volume 351, Issue 6268, pp. 53 - 58
Eukaryotic cells coordinate growth with the availability of nutrients through the mechanistic target of rapamycin complex 1 (mTORC1), a master growth... 
SKELETAL-MUSCLE | PEROXIREDOXINS | MTORC1 | ACTIVATION | COMPLEX | PROTEIN | RAG GTPASES | AMINO-ACIDS | MULTIDISCIPLINARY SCIENCES | SESTRINS | SIGNAL INTEGRATION
Journal Article
Biology of Reproduction, ISSN 0006-3363, 2015, Volume 92, Issue 2
ABSTRACT The greatest limitation to reproductive performance in most mammals, including humans, is embryonic mortality, which, in general, claims 20%–40% of... 
SPP1 | trophectoderm | MTORC1 | arginine | sheep
Journal Article
Circulation research, ISSN 0009-7330, 5/2014, Volume 114, Issue 10, pp. 1576 - 1584
Journal Article
Methods in Enzymology, ISSN 0076-6879, 01/2017, Volume 588, pp. xxv - xxxi
Journal Article
Methods in Enzymology, ISSN 0076-6879, 01/2017, Volume 587, pp. xxiii - xxix
Journal Article
Biochemical Journal, ISSN 0264-6021, 2019, Volume 476, Issue 5, pp. 779 - 781
Colorectal cancer is one of the most common forms of cancer in the world, with more than half a million new cases annually. Amongst the most promising new... 
MTORC1 | SUPPRESSION | BIOCHEMISTRY & MOLECULAR BIOLOGY | GROWTH
Journal Article
Autophagy, ISSN 1554-8627, 08/2019, Volume 15, Issue 8, pp. 1489 - 1491
Macroautophagy/autophagy is a conserved degradative pathway that host cells use to deal with invading pathogens. Despite significant overlap with... 
AMPK | Xenophagy | MTORC1 | ULK1 | autophagy | outer membrane vesicles | CELL BIOLOGY
Journal Article
Cellular Signalling, ISSN 0898-6568, 01/2019, Volume 53, pp. 59 - 67
The proton-coupled amino acid transporter PAT1 has been postulated to regulate the amino acid-stimulated mTORC1 through two different mechanisms, either it... 
Amino acids | PAT1 | mTORC1 | Lysosome | GLYCOSYLATION | CARRIER | CELL BIOLOGY
Journal Article
Autophagy, ISSN 1554-8627, 06/2019, Volume 15, Issue 6, pp. 1120 - 1121
Recently, we identified a vertebrate-specific macroautophagy/autophagy regulator, RUBCNL/Pacer, which promotes autolysosome formation by engaging the class III... 
HOPS complex | PI3KC3 | Pacer | Rubicon | STX17 | mTORC1 | CELL BIOLOGY
Journal Article
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, ISSN 0021-8561, 05/2019, Volume 67, Issue 17, pp. 4849 - 4859
Sestrin2 (SESN2) negatively regulates the mammalian target of rapamycin complex 1 (mTORC1) pathway and casein synthesis in response to amino acid (AA)... 
LOCALIZATION | ACTIVATION | RAG GTPASES | cow mammary epithelial cell | amino acid | FOOD SCIENCE & TECHNOLOGY | mTORC1 pathway | casein synthesis | PROLIFERATION | PROTEIN-SYNTHESIS | MTORC1 | GENE | AMINO-ACIDS | LEUCINE SENSOR | AGRICULTURE, MULTIDISCIPLINARY | SH3BP4 | CHEMISTRY, APPLIED | sestrin2 | Index Medicus
Journal Article
Neuroscience Letters, ISSN 0304-3940, 07/2019, Volume 706, pp. 223 - 230
Hamartin, a component of the tuberous sclerosis complex (TSC) that actively inhibits the mammalian target of rapamycin (mTOR), may mediate the endogenous... 
Hamartin | AZD2014 | Rapamycin | mTORC2 | mTORC1 | TUBEROUS SCLEROSIS GENE | FOCAL CEREBRAL-ISCHEMIA | TSC1 | ENDOPLASMIC-RETICULUM STRESS | CELL-GROWTH | IDENTIFICATION | NEUROSCIENCES | DUAL MTORC1 | BRAIN | Stroke (Disease) | Proteins | Neurosciences | Ischemia | Neurons | Cell death | Tuberous sclerosis | Investigations
Journal Article
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