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Tetrahedron, ISSN 0040-4020, 04/2018, Volume 74, Issue 14, pp. 1581 - 1612
Journal Article
Chemical Communications, ISSN 1359-7345, 2019, Volume 55, Issue 19, pp. 2841 - 2844
S-Arylation of cysteine residues is an increasingly powerful tool for site-specific modification of proteins, providing novel structure and electronic... 
BIOMOLECULES | BIOCONJUGATION | CHEMISTRY, MULTIDISCIPLINARY | MACROCYCLIZATION | UNPROTECTED PEPTIDES | PROTEIN MODIFICATION
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 03/2017, Volume 56, Issue 12, pp. 3177 - 3181
Journal Article
Organic Letters, ISSN 1523-7060, 2019, Volume 21, Issue 7, pp. 2029 - 2032
A biomimetic one-step ligase-catalyzed cyclo-oligomerization mediated by butelase 1, an Asn/Asp-specific ligase, is introduced that is time-, concentration-,... 
SIZE | ANTIMICROBIAL PEPTIDE | ANTIBACTERIAL | CHEMISTRY, ORGANIC | CYCLIZATION | MACROCYCLIZATION | MEMBRANOLYTIC SELECTIVITY
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 06/2018, Volume 140, Issue 22, pp. 6797 - 6800
Targeting tryptophan is a promising strategy to achieve high levels of selectivity for peptide or protein modification. A chemoselective peptide modification... 
VISIBLE-LIGHT PHOTOCATALYSIS | ALKYLATION | TRANSITION-METAL | SELECTIVE BIOCONJUGATION | FUTURE | CHEMISTRY, MULTIDISCIPLINARY | MACROCYCLIZATION | FEATURES
Journal Article
Accounts of Chemical Research, ISSN 0001-4842, 06/2018, Volume 51, Issue 6, pp. 1475 - 1486
Conspectus Multicomponent reactions (MCRs) encompass an exciting class of chemical transformations that have proven success in almost all fields of synthetic... 
CYCLIC LIPOPEPTIDES | PEPTIDES | ANALOGS | TYROSINE BIOCONJUGATION | BUILDING-BLOCKS | ISOCYANIDES | UGI REACTION | CHEMISTRY, MULTIDISCIPLINARY | MACROCYCLIZATION | STRATEGIES | HYBRIDS
Journal Article
ACCOUNTS OF CHEMICAL RESEARCH, ISSN 0001-4842, 03/2014, Volume 47, Issue 3, pp. 925 - 938
During the last century, conceptual advances in organo-metallic chemistry were often rapidly embraced by target oriented synthesis. Feedback provided by such... 
REARRANGEMENT | ALKYNE METATHESIS | ENANTIOSELECTIVE SYNTHESIS | (-)-RHAZINILAM | COMPLEXES | CHEMISTRY, MULTIDISCIPLINARY | CYCLOISOMERIZATION REACTIONS | MACROCYCLIZATION | F METHYL-ESTER | ELEMENTARY STEPS | ENYNES | Gold | Chemical properties | Research | Catalysis | Platinum | Synthesis (chemistry) | Cross coupling | Synthesis | Olefins | Metalorganic compounds | Metathesis | Arenas
Journal Article
Synlett, ISSN 0936-5214, 09/2017, Volume 28, Issue 15, pp. 1913 - 1916
Abstract Cyclic peptides are attracting attention of medicinal chemists due to their increased stability in biological milieu as well as improved target... 
cluster | 2-APBA | Dap | peptide cyclization | iminoboronate | reversible | CHEMISTRY, ORGANIC | MACROCYCLIZATION
Journal Article
Chembiochem : a European journal of chemical biology, ISSN 1439-4227, 5/2018, Volume 19, Issue 10, pp. 1031 - 1035
Peptide macrocycles are widely utilized in the development of high affinity ligands including stapled α-helices. The linear rigidity of a 1,3-diynyl linkage... 
Glaser | chemoselective | peptide stapling | peptide macrocyclization | copper acetylide
Journal Article
Organic Letters, ISSN 1523-7060, 04/2019, Volume 21, Issue 7, pp. 2095 - 2100
In Nature, multicyclic peptides constitute a versatile molecule class with various biological functions. For their pharmaceutical exploitation, chemical... 
SYSTEM | SITE | SCAFFOLDS | MACROCYCLIZATION | CYCLIZATION | DISULFIDE-RICH PEPTIDES | HYBRIDS | CHEMISTRY, ORGANIC | Letter
Journal Article
Organic Letters, ISSN 1523-7060, 12/2007, Volume 9, Issue 26, pp. 5473 - 5476
Leucinol and valinol have been identified as efficient organocatalysts for the aldol reaction of isatin and its derivatives (as examples of activated,... 
MANNICH | METHODOLOGY | PINACOL MACROCYCLIZATION CASCADE | DIAZONAMIDE-A | ISATINS | CONSTRUCTION | 1ST TOTAL-SYNTHESIS | CHEMISTRY | CHEMISTRY, ORGANIC | CONDENSATION | PROLINE
Journal Article
The Plant Journal, ISSN 0960-7412, 06/2019, Volume 98, Issue 6, pp. 988 - 999
Journal Article
Chemical Science, ISSN 2041-6520, 08/2019, Volume 10, Issue 34, pp. 7982 - 7987
Directly introducing a beneficial functional group into biomolecules under mild, clean and easy-to-handle conditions is of great importance in the field of... 
Journal Article
The Journal of Organic Chemistry, ISSN 0022-3263, 11/2018, Volume 83, Issue 21, pp. 13395 - 13401
Penicipyrrodiether A, an adduct of GKK1032 analogue and phenol A derivative, was isolated from a culture of marine-associated fungus Penicillium sp. ZZ380 and... 
ENDOPHYTES | PYRROSPIRONES | NEONECTRIA-RAMULARIAE | A-C | CHEMISTRY, ORGANIC | PYRROCIDINE | ACREMONIUM-ZEAE | METABOLITE | HIRSUTELLONE B | DIRECT 13-MEMBERED MACROCYCLIZATION | ALKALOIDS
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 04/2019, Volume 58, Issue 15, pp. 4998 - 5002
Peptide macrocyclization is often a slow process, plagued by epimerization and cyclodimerization. Herein, we describe a new method for peptide macrocyclization... 
macrocyclization | thioamide | cyclic peptide | Peptides | Extrusion | Transformation | Tethering
Journal Article
Organic and Biomolecular Chemistry, ISSN 1477-0520, 2017, Volume 15, Issue 19, pp. 4086 - 4095
The perfluoroheteroaromatic reagent pentafluoropyridine has proved to be a highly reactive electrophile, undergoing SNAr arylation reactions in the presence of... 
PENTAFLUOROPYRIDINE | TETRAFLUOROPYRIMIDINE | CHYMOTRYPSIN | ANALOG | UNPROTECTED PEPTIDES | OXYTOCIN | CHEMISTRY, ORGANIC | POLYHALOGENATED HETEROCYCLIC-COMPOUNDS | DERIVATIVES | MACROCYCLIZATION | POLYPEPTIDES
Journal Article
Chemical Science, ISSN 2041-6520, 01/2015, Volume 6, Issue 1, pp. 144 - 151
A new strategy for determining thermodynamic effective molarities (EM) for macrocylisation reactions using dynamic combinatorial chemistry under dilute... 
LIBRARIES | THERMODYNAMIC CONTROL | FORMALDEHYDE ACETALS | COVALENT CHEMISTRY | MOLECULAR RECOGNITION | SYSTEMS CHEMISTRY | COOPERATIVITY | IMINE METATHESIS | CHEMISTRY, MULTIDISCIPLINARY | INDUCED AMPLIFICATION | MACROCYCLIZATION
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 08/2009, Volume 48, Issue 33, pp. 6112 - 6116
Tighten your belt: [12]Cycloparaphenylene, the sidewall segment of a carbon nanotube (see picture), has been synthesized in a selective manner through stepwise... 
palladium | macrocyclization | cross‐coupling | aromaticity | cycloparaphenylenes | ORGANOBORON COMPOUNDS | TUBE-SHAPED MOLECULES | CARBON SKELETON | DOUBLE-STRANDED CYCLE | CHEMISTRY, MULTIDISCIPLINARY | ARYLBORONIC ACIDS | CROSS-COUPLING REACTIONS | NONPLANAR AROMATIC-COMPOUNDS | cross-coupling | H BOND ARYLATION | PI-SYSTEMS | BELT REGION
Journal Article