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Journal of Immunotoxicology, ISSN 1547-691X, 01/2020, Volume 17, Issue 1, pp. 1 - 9
Nonimmediate drug hypersensitivity reactions (niDHRs) range from mild-type maculopapular exanthema (MPE) to severe type Stevens-Johnson syndrome (SJS) and... 
maculopapular exanthema (MPE) | Complement | Stevens-Johnson syndrome (SJS) | hypersensitivity | toxic epidermal necrolysis (TEN) | maculopapular exanthema (mpe) | stevens–johnson syndrome (sjs) | complement | toxic epidermal necrolysis (ten)
Journal Article
Allergy, ISSN 0105-4538, 09/2019, Volume 74, Issue 9, pp. 1769 - 1779
Background Drug‐induced maculopapular exanthemas (MPEs) are mediated by Th1 CD4+ T cells. One of the mechanisms of control of Th1 cells in homeostasis is the... 
Galectin‐9 | maculopapular exanthema | drug allergy | Tim3 | checkpoint inhibitor | Cell proliferation | Immunohistochemistry | Flow cytometry | Dendritic cells | Exanthema | Homeostasis | Lymphocytes T | Drug development | Blood | CD4 antigen | Monocytes | Immunological diseases | Immune checkpoint | Immunology | Lymphocytes | Peripheral blood | Skin
Journal Article
Pharmacology and Therapeutics, ISSN 0163-7258, 05/2019, Volume 197, pp. 122 - 152
Individuals differ substantially in their response to pharmacological treatment. Personalized medicine aspires to embrace these inter-individual differences... 
COST-EFFECTIVENESS ANALYSIS | CUTANEOUS ADVERSE-REACTIONS | HLA CLASS-I | ACUTE LYMPHOBLASTIC-LEUKEMIA | ANTHRACYCLINE-INDUCED CARDIOTOXICITY | PHARMACOLOGY & PHARMACY | STEVENS-JOHNSON-SYNDROME | PHARMACOGENETICS IMPLEMENTATION CONSORTIUM | SINGLE-NUCLEOTIDE POLYMORPHISMS | INDUCED HYPERSENSITIVITY REACTIONS | GENOME-WIDE ASSOCIATION | Sulfites | Epigenetic inheritance | Pharmacogenetics | Multiple sclerosis | Methyltransferases | Glutathione transferase | Leukemia | Abacavir | Machine learning | Cystic fibrosis | Tretinoin | eQTL, Quantitative trait locus | ALL, Acute lymphoblastic leukemia | CNVs, Copy number variations | CPIC, Clinical Pharmacogenetics Implementation Consortium | CFTR, Cystic fibrosis transmembrane conductance regulator | DNMTs, DNA methyltransferases | UM, Ultrarapid metabolism | MPE, Maculopapular exanthema | 5hmC, 5-hydroxymethylcytosine | ABC-HSS, Abacavir hypersensitivity syndrome | MS, Multiple sclerosis | DHR, Drug hypersensitivity reactions | CAT, Catalase | HDACs, Histone deacetylases | 5fC, 5- Formylcytosine | RA, Retinoic acid | TAB-Seq, TET-assisted bisulfite sequencing | GPCR, G-protein coupled receptor | MAF, Minor allele frequencies | PRC2, Polycomb repressive complex 2 | DPWG, Dutch Pharmacogenetics Working Group | PM, Poor metabolism | 5caC, 5- Carboxylcytosine | GST, Glutathione-S-transferase | DRESS, Drug rash with eosinophilia and systemic symptoms | SCAR, Severe cutaneous adverse reaction | SJS, Stevens-Johnson syndrome | TEN, Toxic epidermal necrolysis | ChIP, Chromatin immunoprecipitation | oxBS-seq, Oxidative bisulfite sequencing | DIHS, Drug-induced hypersensitivity syndrome | DILI, Drug-induced liver injury | SNVs, Single nucleotide variations | PTMs, Posttranslational modifications
Journal Article
Journal Article
European Journal of Clinical Pharmacology, ISSN 0031-6970, 2/2011, Volume 67, Issue 2, pp. 121 - 127
Journal Article
Allergy, ISSN 0105-4538, 06/2008, Volume 63, Issue 6, pp. 712 - 719
Background:  Maculopapular exanthema (MPE) is the most frequent clinical manifestation of nonimmediate allergic reactions to drugs and T helper 1 (Th1)... 
cytokines | maculopapular exanthema | chemokines | T cells | allergic drug reactions | Allergic drug reactions | Cytokines | Maculopapular exanthema | Chemokines | CCL27-CCR10 INTERACTIONS | INVOLVEMENT | TRAFFICKING | RECEPTOR | IMMUNOLOGY | CXCL10 | ALLERGY | CUTANEOUS REACTIONS | DISEASE | MEMORY T-CELLS | HYPERSENSITIVITY | Tumor Necrosis Factor-alpha - metabolism | Chemokine CCL20 - metabolism | Skin - metabolism | Humans | Middle Aged | Male | Th2 Cells - immunology | Interferon-gamma - metabolism | Th1 Cells - immunology | CD4-Positive T-Lymphocytes - immunology | Th1 Cells - metabolism | Chemokine CCL20 - immunology | Chemokine CXCL10 - immunology | Tumor Necrosis Factor-alpha - immunology | CD8-Positive T-Lymphocytes - metabolism | Adult | Female | Exanthema - metabolism | Chemokine CCL27 - metabolism | Drug Eruptions - immunology | Skin - immunology | Exanthema - immunology | Receptors, Chemokine - metabolism | CD4-Positive T-Lymphocytes - metabolism | Chemokine CXCL9 - immunology | Receptors, Chemokine - immunology | Th2 Cells - metabolism | Drug Eruptions - metabolism | Chemokine CXCL9 - metabolism | Interferon-gamma - immunology | Chemokine CCL27 - immunology | CD8-Positive T-Lymphocytes - immunology | Chemokine CXCL10 - metabolism | Tumor necrosis factor | Leucocytes | Side effects | Chemistry | Immunology | Dermatology | Skin | Histology | Allergies | Cells | Index Medicus
Journal Article
Journal Article
Journal of Dermatological Science, ISSN 0923-1811, 2013, Volume 73, Issue 2, pp. 101 - 109
Journal Article