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2016, 1st ed. 2016, Springer briefs in biochemistry and molecular biology, ISBN 3319302752, xiv, 116 pages
This book has been conceives as a brief introduction to biomembranes physical chemistry for undergraduate students of sciences, and it is particularly... 
Lipid membranes | Lipids | Membrane proteins | Bilayer lipid membranes | Physics | Bioorganic chemistry | Life Sciences | Protein Science | Biophysics and Biological Physics | Bioorganic Chemistry
Book
2010, Advances in experimental medicine and biology, ISBN 9781441963277, Volume 677
Web Resource
2010, Advances in experimental medicine and biology, ISBN 9781441963260, Volume 677.
Web Resource
The Plant Cell, ISSN 1040-4651, 11/2012, Volume 24, Issue 11, pp. 4465 - 4482
Supramolecular organization of enzymes is proposed to orchestrate metabolic complexity and help channel intermediates in different pathways. Phenylpropanoid... 
Proteins | Enzymes | Lignin | Protein metabolism | Sterols | RESEARCH ARTICLES | Hematocrit | Fluorescence | Cytochromes | Plants | Plant cells | ENDOPLASMIC-RETICULUM MEMBRANE | MOLECULAR-INTERACTIONS | ARABIDOPSIS-THALIANA | BIOCHEMISTRY & MOLECULAR BIOLOGY | CINNAMIC ACID | PHENYLALANINE AMMONIA-LYASE | CYTOCHROME P450 REDUCTASE | PLANT SCIENCES | CELL BIOLOGY | PHENYLPROPANOID PATHWAY | TANDEM AFFINITY PURIFICATION | ENZYME COMPLEXES | BINDING PROTEIN-1 | Green Fluorescent Proteins | Protein Multimerization | Cytochrome P-450 Enzyme System - metabolism | Endoplasmic Reticulum - metabolism | Trans-Cinnamate 4-Monooxygenase - genetics | Acyltransferases - metabolism | Recombinant Fusion Proteins | Coenzyme A Ligases - metabolism | Arabidopsis Proteins - metabolism | Trans-Cinnamate 4-Monooxygenase - metabolism | Lignin - metabolism | Plants, Genetically Modified | Membrane Proteins - metabolism | Transgenes | Acyl Coenzyme A - metabolism | Arabidopsis Proteins - genetics | Hydroxylation | Hydroxybenzoates - metabolism | Membrane Proteins - genetics | Tobacco - metabolism | Arabidopsis - metabolism | Protein Interaction Mapping | Arabidopsis - genetics | Plant Leaves - genetics | Plant Leaves - metabolism | Tobacco - genetics | Cytochrome P-450 Enzyme System - genetics | Phytochemistry | Physiological aspects | Biosynthesis | Research | Protein-protein interactions | Membrane proteins | Index Medicus | Life Sciences | Molecular biology | Cellular Biology | Biochemistry, Molecular Biology
Journal Article
2012, ISBN 0470874325, xii, 289
Examines new research on the role of cholesterol in regulating ion channels and receptors and its effect on health Drawing together and analyzing all the... 
Ion channels | Metabolism | Cholesterol | Membrane proteins | Life Sciences | Science | Biology | Molecular Biology
Book
EMBO reports, ISSN 1469-221X, 01/2010, Volume 11, Issue 1, pp. 45 - 51
Autophagy is the cellular homeostatic pathway that delivers large cytosolic materials for degradation in the lysosome. Recent evidence indicates that autophagy... 
mitophagy | Nix | LC3 | GABARAP | selective autophagy | Selective autophagy | Mitophagy | APOPTOSIS | PROTEIN | RETICULOCYTE MATURATION | UBIQUITIN | BNIP3 | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL-DEATH | CELL BIOLOGY | STRUCTURAL BASIS | DEGRADATION | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Humans | Cercopithecus aethiops | Molecular Sequence Data | Substrate Specificity | Autophagy - physiology | Mitochondrial Proteins - genetics | Proto-Oncogene Proteins - chemistry | Mitochondrial Proteins - metabolism | Tumor Suppressor Proteins - chemistry | Tumor Suppressor Proteins - genetics | Membrane Proteins - metabolism | Binding Sites | Proto-Oncogene Proteins - metabolism | Amino Acid Sequence | Tumor Suppressor Proteins - metabolism | Membrane Proteins - genetics | Cells, Cultured | Ubiquitin-Protein Ligases - metabolism | Proto-Oncogene Proteins - genetics | Mitochondria - metabolism | Saccharomyces cerevisiae Proteins - genetics | Blotting, Western | Amino Acid Motifs | Autophagy-Related Protein 8 Family | Animals | Membrane Proteins - chemistry | Reticulocytes - cytology | Mitochondrial Proteins - chemistry | Saccharomyces cerevisiae Proteins - metabolism | Protein Binding | Mice | Receptors, GABA-A - metabolism | COS Cells | Proteins | Mitochondria | Cellular biology | Cytoplasm | Index Medicus | Scientific Report
Journal Article
Nature Neuroscience, ISSN 1097-6256, 11/2012, Volume 15, Issue 11, pp. 1488 - 1497
FUS/TLS (fused in sarcoma/translocated in liposarcoma) and TDP-43 are integrally involved in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia.... 
NEURODEGENERATIVE DISEASE | GENE | AMYOTROPHIC-LATERAL-SCLEROSIS | FAMILY PROTEINS | FUS PATHOLOGY | MUTATIONS | FRONTOTEMPORAL LOBAR DEGENERATION | BINDING | NEUROSCIENCES | BRAIN | NASCENT TRANSCRIPTION | RNA, Small Interfering - genetics | Protein Binding - genetics | Oligonucleotide Array Sequence Analysis | Humans | tau Proteins - metabolism | Gene Expression Profiling | RNA, Messenger - metabolism | Kv Channel-Interacting Proteins - metabolism | Brain - metabolism | Frontotemporal Dementia - metabolism | RNA Splicing - genetics | Frontotemporal Dementia - genetics | RNA-Binding Protein FUS - deficiency | Amyotrophic Lateral Sclerosis - genetics | Cell Cycle Proteins - metabolism | Ubiquitin-Protein Ligases - metabolism | RNA-Binding Protein FUS - genetics | Mice, Knockout | Motor Neurons - metabolism | Amyotrophic Lateral Sclerosis - pathology | Shal Potassium Channels - metabolism | Brain - pathology | Mice | Neurofilament Proteins - metabolism | RNA, Small Interfering - metabolism | Immunoprecipitation | Spinal Cord - metabolism | DNA-Binding Proteins - deficiency | DNA-Binding Proteins - metabolism | tau Proteins - genetics | Cell Cycle Proteins - genetics | Female | RNA Precursors - metabolism | Excitatory Amino Acid Transporter 2 - genetics | Membrane Proteins - metabolism | Frontotemporal Dementia - pathology | Gene Expression Regulation - genetics | Mice, Inbred C57BL | RNA, Messenger - genetics | RNA Precursors - genetics | Protein Structure, Tertiary - genetics | RNA-Binding Protein FUS - metabolism | DNA-Binding Proteins - genetics | Excitatory Amino Acid Transporter 2 - metabolism | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Histone-Lysine N-Methyltransferase - metabolism | Amyotrophic Lateral Sclerosis - metabolism | Neural Cell Adhesion Molecules - metabolism | Neural Stem Cells - metabolism | Cell Line, Transformed | Amyotrophic lateral sclerosis | Development and progression | Genetic aspects | Messenger RNA | Health aspects | Index Medicus
Journal Article
Molecular Cell, ISSN 1097-2765, 2005, Volume 17, Issue 3, pp. 393 - 403
Apoptosis is initiated when Bcl-2 and its prosurvival relatives are engaged by proapoptotic BH3-only proteins via interaction of its BH3 domain with a groove... 
CYTOCHROME-C | COMPLEX | SURVIVAL FACTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | MITOCHONDRIA | BIM | RELEASE | PEPTIDE | CELL-DEATH | FAMILY | MEMBER | CELL BIOLOGY | Humans | Molecular Sequence Data | Proto-Oncogene Proteins - chemistry | Neoplasm Proteins - metabolism | Genetic Complementation Test | Proto-Oncogene Proteins c-bcl-2 - metabolism | Bcl-2-Like Protein 11 | Carrier Proteins - chemistry | Proto-Oncogene Proteins c-bcl-2 - chemistry | Membrane Proteins - metabolism | Neoplasm Proteins - genetics | Peptide Fragments - genetics | Cell Survival - physiology | Binding, Competitive | Protein Structure, Tertiary | Proto-Oncogene Proteins - metabolism | Recombinant Proteins - metabolism | Amino Acid Sequence | bcl-X Protein | Peptide Fragments - metabolism | Membrane Proteins - genetics | Models, Molecular | Recombinant Proteins - chemistry | Neoplasm Proteins - chemistry | Proto-Oncogene Proteins - genetics | Recombinant Proteins - genetics | Proteins - genetics | Sequence Homology, Amino Acid | Carrier Proteins - genetics | Peptide Fragments - chemistry | Animals | Apoptosis Regulatory Proteins | Carrier Proteins - metabolism | Proteins - metabolism | Membrane Proteins - chemistry | Models, Biological | Myeloid Cell Leukemia Sequence 1 Protein | Biosensing Techniques | Ligands | Mice | Apoptosis - physiology | Proteins - chemistry | In Vitro Techniques | Proto-Oncogene Proteins c-bcl-2 - genetics | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 03/2010, Volume 464, Issue 7287, pp. 431 - 435
Activating mutations in KRAS and BRAF are found in more than 30% of all human tumours and 40% of melanoma, respectively, thus targeting this pathway could have... 
SELECTIVE INHIBITOR | POTENT | EFFICACY | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | IN-VIVO | C-RAF | HETERODIMERIZATION | B-RAF | PROTEIN-KINASE KINASE | CANCER | Neoplasms - metabolism | ras Proteins - genetics | Proto-Oncogene Proteins p21(ras) | Diphenylamine - pharmacology | raf Kinases - antagonists & inhibitors | Humans | Protein Multimerization | ras Proteins - metabolism | Protein Transport - drug effects | Extracellular Signal-Regulated MAP Kinases - metabolism | raf Kinases - metabolism | Diphenylamine - analogs & derivatives | Mitogen-Activated Protein Kinase Kinases - metabolism | Adenosine Triphosphate - metabolism | Indoles - pharmacology | Benzamides - pharmacology | Cell Membrane - metabolism | raf Kinases - genetics | Cell Membrane - drug effects | Proto-Oncogene Proteins B-raf - metabolism | Proto-Oncogene Proteins B-raf - chemistry | Pyrazoles - pharmacology | Protein Structure, Tertiary | Proto-Oncogene Proteins - metabolism | Cell Line | Indenes - pharmacology | raf Kinases - chemistry | Proto-Oncogene Proteins c-raf - genetics | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | Neoplasms - enzymology | Proto-Oncogene Proteins - genetics | Enzyme Activation - drug effects | Sulfonamides - pharmacology | Proto-Oncogene Proteins c-raf - metabolism | Neoplasms - drug therapy | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Xenograft Model Antitumor Assays | Animals | MAP Kinase Signaling System - drug effects | Protein Kinase Inhibitors - therapeutic use | Proto-Oncogene Proteins B-raf - genetics | Proto-Oncogene Proteins c-raf - deficiency | Cell Proliferation - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | Neoplasms - pathology | Ras genes | Growth | Physiological aspects | Cellular signal transduction | Genetic aspects | Research | Mitogen-activated protein kinases | Competition | Clinical trials | Enzymes | Kinases | Index Medicus | Proteins | Cellular | Inhibitors | Pathways | Tumours | Signalling | Dimerization
Journal Article
Cell, ISSN 0092-8674, 2006, Volume 124, Issue 3, pp. 573 - 586
How is the characteristic shape of a membrane bound organelle achieved? We have used an in vitro system to address the mechanism by which the tubular network... 
YEAST | LOCALIZATION | NEURITE OUTGROWTH | POLYPOSIS LOCUS | INTERACTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | NOGO-A | FUNCTIONAL DOMAINS | GENE FAMILY | IDENTIFICATION | SACCHAROMYCES-CEREVISIAE | CELL BIOLOGY | Saccharomyces cerevisiae - genetics | Humans | Cercopithecus aethiops | Endoplasmic Reticulum - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Saccharomyces cerevisiae - metabolism | Transfection | Membrane Transport Proteins - genetics | Female | Membrane Transport Proteins - metabolism | Membrane Proteins - metabolism | Nogo Proteins | Membrane Proteins - classification | Intracellular Signaling Peptides and Proteins - genetics | Calcium Signaling | Recombinant Proteins - metabolism | Membrane Proteins - genetics | Oocytes - metabolism | Rats | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Saccharomyces cerevisiae Proteins - genetics | Membrane Transport Proteins - chemistry | Animals | Membrane Proteins - chemistry | Intracellular Signaling Peptides and Proteins - chemistry | Saccharomyces cerevisiae Proteins - metabolism | Myelin Proteins | In Vitro Techniques | COS Cells | Saccharomyces cerevisiae Proteins - chemistry | Usage | Physiological aspects | Immunoblotting | Research | Brewer's yeast | Endoplasmic reticulum | Membrane proteins | Lipids | Aquaporins | Synthesis | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2011, Volume 108, Issue 30, pp. 12313 - 12318
Journal Article