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Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 03/2014, Volume 18, Issue 3, pp. 468 - 479
Activation of poly(ADP‐ribose) polymerases (PARPs) is considered a key event in the molecular and cellular processes leading from acute asthma attacks to... 
asthma‐like reaction | hydroxyl‐dimethylaminomethyl‐thieno[2,3‐c]isoquinolin‐5(4H)‐one (HYDAMTIQ) | histamine release | poly (ADP‐ribose) polymerase (PARP) | airway inflammation and remodelling | Asthma-like reaction | Airway inflammation and remodelling | Poly (ADP-ribose) polymerase (PARP) | Histamine release | Hydroxyl-dimethylaminomethyl-thieno[2,3-c]isoquinolin-5(4H)-one (HYDAMTIQ) | MEDICINE, RESEARCH & EXPERIMENTAL | ACTIVATION | hydroxyl-dimethylaminomethyl-thieno | RAT | MAST-CELLS | CELL BIOLOGY | MURINE MODEL | SENSITIZED GUINEA-PIGS | ADP-RIBOSE POLYMERASE | INHALED ANTIGEN | INFLAMMATION | GENE-EXPRESSION | 3-c]isoquinolin-5(4H)-one (HYDAMTIQ) | poly (ADP-ribose) polymerase (PARP) | NF-KAPPA-B | asthma-like reaction | Bronchoalveolar Lavage Fluid | Inflammation - pathology | Leukocytes - pathology | Thiophenes - therapeutic use | Bronchial Hyperreactivity - immunology | Ovalbumin - immunology | Bronchial Hyperreactivity - drug therapy | Isoquinolines - pharmacology | Allergens - immunology | Asthma - immunology | Histamine Release | Mast Cells - metabolism | Lung - pathology | Guinea Pigs | Asthma - physiopathology | Cytokines - metabolism | Enzyme Inhibitors - pharmacology | Thiophenes - pharmacology | Asthma - drug therapy | Enzyme Inhibitors - therapeutic use | Mast Cells - drug effects | Poly(ADP-ribose) Polymerase Inhibitors | Bronchial Hyperreactivity - pathology | Poly Adenosine Diphosphate Ribose - metabolism | Poly(ADP-ribose) Polymerases - metabolism | Animals | Lung - drug effects | Isoquinolines - therapeutic use | Leukocytes - drug effects | Airway Remodeling - drug effects | Oxidative Stress - drug effects | Asthma - pathology | Histamine | Allergens | Hydroxides | Sugars | Monosaccharides | Asthma | Hyperplasia | Smooth muscle | Leukocytes | ADP | Mitochondria | Methacholine | Enzymes | Antigens | Free radicals | Cytokines | Leukocytes (eosinophilic) | Abnormalities | Gene expression | Malondialdehyde | Allergies | Endothelium | Reactivity | Tumor necrosis factor | Guinea pigs | Mast cells | Eosinophils | Oxidative stress | DNA damage | Interleukin | Remodeling | Respiratory tract | Dyspnea | Ribose | Cell cycle | Tumor necrosis factor-TNF | Alveoli | Ovalbumin | Damage assessment | Muscles | Poly(ADP-ribose) polymerase | Inflammation | Cough | Inhalation | Polymerase | Deoxyguanosine | Lungs | Collagen | Laboratory animals | Respiration | Peritoneum | Apoptosis | Index Medicus | Original | hydroxyl-dimethylaminomethyl-thieno[2,3-c]isoquinolin-5(4H)-one (HYDAMTIQ)
Journal Article
Chest, ISSN 0012-3692, 2016, Volume 150, Issue 6, pp. 1333 - 1340
Journal Article
Respirology, ISSN 1323-7799, 12/2019, Volume 24, Issue 12, pp. 1176 - 1182
ABSTRACT Background and objective Obstructive sleep apnoea (OSA) and asthma are associated, and nocturnal breathing difficulty that is usually identified as... 
asthma | sleep apnoea, obstructive | bronchial hyper‐reactivity | airway resistance | sleep apnoea syndromes | Sleep disorders | Sleep | Apnea | Methacholine | Sleep apnea | Regression analysis | Asthma
Journal Article
Journal Article
Respirology, ISSN 1323-7799, 04/2019, Volume 24, Issue 4, pp. 338 - 344
ABSTRACT Background and objective Asthma is characterized by airway hyperreactivity and airway inflammation. We previously demonstrated that adults with mild... 
induced sputum | bronchial challenge | lung function | chronic mechanical strain | CHALLENGE | RESPONSIVENESS | REPEATABILITY | DEEP INSPIRATION | RESPIRATORY SYSTEM | IN-VIVO | METHACHOLINE | Asthma in children | Continuous positive airway pressure | Inflammation | Respiratory tract | Corticoids | Respiratory tract diseases | Children | Methacholine | Asthma
Journal Article
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, ISSN 1040-0605, 05/2019, Volume 316, Issue 5, pp. L757 - L763
Journal Article
Clinical & Experimental Allergy, ISSN 0954-7894, 07/2017, Volume 47, Issue 7, pp. 909 - 917
Journal Article