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crystal-structure (33) 33
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New Phytologist, ISSN 0028-646X, 7/2013, Volume 199, Issue 1, pp. 188 - 202
Arbuscular mycorrhizal (AM) symbiosis is stimulated by phosphorus (P) limitation and contributes to P and nitrogen (N) acquisition. However, the effects of... 
Symbiosis | Oxidases | Phosphates | Full papers | Microbial colonization | Plant nutrition | Genes | Plant roots | Gene expression regulation | Plants | Nitrogen | NADPH | oxidase | edicago truncatula | nitrogen | strigolactones | phosphate | arbuscular mycorrhiza | methylerythritol phosphate | nutrient stress | Medicago truncatula | Nitrogen (N) | NADPH oxidase | Phosphate | Arbuscular mycorrhiza (AM) | Nutrient stress | Methylerythritol phosphate | Strigolactones | arbuscular mycorrhiza (AM) | nitrogen (N) | SCARECROW-LIKE 3 | PLANT SCIENCES | CORTICAL-CELLS | RESPONSES | TRANSPORT | GLOMUS-INTRARADICES | METABOLISM | GENE-EXPRESSION | ROOTS | STARVATION | ARABIDOPSIS | Medicago truncatula - genetics | Erythritol - analogs & derivatives | Phosphate Transport Proteins - metabolism | Stress, Physiological | Symbiosis - physiology | Transcriptome | Mycorrhizae - physiology | Medicago truncatula - microbiology | Terpenes - metabolism | Gene Expression Regulation, Plant | Erythritol - metabolism | Plant Proteins - metabolism | Phosphate Transport Proteins - genetics | Sugar Phosphates - genetics | Nitrogen - metabolism | Plant Roots - metabolism | Glomeromycota - physiology | Erythritol - genetics | Signal Transduction - genetics | Medicago truncatula - metabolism | Plant Roots - microbiology | Plant Proteins - genetics | Phosphates - metabolism | Sugar Phosphates - metabolism | Phosphorus - metabolism | Fungi | Legumes | Beans | Analysis | Plant genetics | Mimosaceae | Index Medicus
Journal Article
Plant, Cell & Environment, ISSN 0140-7791, 02/2013, Volume 36, Issue 2, pp. 429 - 437
The methylerythritol phosphate (MEP) pathway in plants produces the prenyl precursors for all plastidic isoprenoids, including carotenoids and quinones. The... 
MEP pathway | isoprenoids | methylerythritol cyclodiphosphate (MEcDP) | hydroxymethylbutenyl diphosphate synthase (HDS) | dimethylallyl diphosphate (DMADP) | Hydroxymethylbutenyl diphosphate synthase (HDS) | Dimethylallyl diphosphate (DMADP) | Methylerythritol cyclodiphosphate (MEcDP) | Isoprenoids | DIFFERENT ENVIRONMENTAL-CONDITIONS | CHLOROPLASTS | NON-MEVALONATE PATHWAY | 4FE-4S PROTEIN | PLANT SCIENCES | ASPEN LEAVES | BIOSYNTHESIS | DIPHOSPHATE SYNTHASE GCPE | EMISSION | 2-C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE | Darkness | Erythritol - analogs & derivatives | Erythritol - chemistry | Populus - radiation effects | Chromatography, High Pressure Liquid | Acclimatization - radiation effects | Hemiterpenes - metabolism | Reference Standards | Time Factors | Light | Mass Spectrometry | Populus - metabolism | Nitrogen - pharmacology | Erythritol - metabolism | Plant Leaves - drug effects | Fosfomycin - analogs & derivatives | Pentanes - metabolism | Metabolome - radiation effects | Fosfomycin - pharmacology | Plant Extracts | Plant Leaves - radiation effects | Metabolome - drug effects | Plant Leaves - metabolism | Butadienes - metabolism | Metabolic Networks and Pathways - drug effects | Acclimatization - drug effects | Metabolic Networks and Pathways - radiation effects | Phosphates | Hydrogen sulfide | Carotenoids | Metabolites | Phytochemistry | Quinone | Nitriles | Mass spectrometry | Index Medicus
Journal Article
FEBS Letters, ISSN 0014-5793, 2003, Volume 541, Issue 1, pp. 115 - 120
The last enzyme (LytB) of the methylerythritol phosphate pathway for isoprenoid biosynthesis catalyzes the reduction of ( E )‐4‐hydroxy‐3‐methylbut‐2‐enyl... 
2- C-Methyl- D-erythritol 4-phosphate pathway | Isoprenoid | Isopentenyl diphosphate | ( E)-4-Hydroxy-3-methylbut-2-enyl diphosphate | Dimethylallyl diphosphate | LytB | EPR, electron paramagnetic resonance | HMBPP | erythritol 4-phosphate pathway | erythritol 4-phosphate | 4-Hydroxy-3-methylbut-2-enyl diphosphate | IPP, isopentenyl diphosphate | MEP, 2 | Methyl | DAF, 5-deazaflavin (10-methyl-5-deazaisoalloxazine) | DMAPP, dimethylallyl diphosphate | ME, 2 | erythritol | (E)-4-Hydroxy-3-methylbut-2-enyl diphosphate | 2-C-Methyl-D-erythritol 4-phosphate pathway | IRON-SULFUR PROTEINS | 2-C-methyl-D-erythritol 4-phosphate pathway | CONVERSION | BIOCHEMISTRY & MOLECULAR BIOLOGY | QUANTITATION | LYASE ACTIVATING ENZYME | isopentenyl diphosphate | (E)-4-hydroxy-3-methylbut-2-enyl diphosphate | CELL BIOLOGY | SYNTHASE | BIOPHYSICS | CLUSTERS | HIGHER-PLANTS | 2-C-METHYL-D-ERYTHRITOL | PYROPHOSPHATE | dimethylallyl diphosphate | isoprenoid | NONMEVALONATE PATHWAY | Diphosphates - metabolism | Escherichia coli - enzymology | Electron Spin Resonance Spectroscopy | Erythritol - analogs & derivatives | Models, Chemical | Oxidoreductases - metabolism | Polyisoprenyl Phosphate Sugars - biosynthesis | Escherichia coli Proteins - metabolism | Iron-Sulfur Proteins - chemistry | Organophosphorus Compounds - metabolism | Oxidoreductases - chemistry | Sugar Phosphates - metabolism | Hemiterpenes | Erythritol - metabolism | Iron-Sulfur Proteins - metabolism | Escherichia coli Proteins - chemistry | NADH, NADPH Oxidoreductases - metabolism | isoprenoids | LytB protein | diphosphate reductase | methylerythritol phosphate | Index Medicus
Journal Article
Bioprocess and Biosystems Engineering, ISSN 1615-7591, 12/2014, Volume 37, Issue 12, pp. 2505 - 2513
Journal Article
FEBS Letters, ISSN 0014-5793, 09/2013, Volume 587, Issue 17, pp. 2806 - 2817
The methylerythritol phosphate (MEP) pathway of ( ) has become an attractive target for anti-malarial drug discovery. This study describes a kinetic model of... 
Drug target | Kinetic model | Malaria | Metabolic control analysis | Methylerythritol phosphate (MEP) | xylulose 5-phosphate synthase | flux control coefficient | HMBPP | IPP | SBML | erythritol synthase | MECPPS | BLAST | Isopentenyl pyrophosphate | FCC | butenyl 4-diphosphate synthase | basic local alignment search tool | erythritol kinase | MECPP | CDPME | GAP | erythritol 2,4-cyclodiphosphate synthase | MEP | DMAPP | xylulose 5-phosphate | DXP | DXS | methylerythritol phosphate | DXR | glyceraldehyde 3-phosphate | 4-(cytidine 5′-diphospho)-2 | PDB | concentration control coefficient | xylulose 5-phosphate reductoisomerase | protein data bank | methyl | 2-phospho-4-(cytidine 5′-diphospho)-2 | BLAST-P | dimethylallyl diphosphate | CCC | butenyl 4-diphosphate reductase | PYR | PSI-BLAST | HMBPPR | pyruvate | HMBPPS | system biology markup language | CDPMEP | protein BLAST | CDPMES | butenyl 4-diphosphate | erythritol 2,4-cyclodiphosphate | position-specific iterated BLAST | CDPMEK | 1-hydroxy-2-methyl-2- | erythritol | 1-deoxy | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | NON-MEVALONATE PATHWAY | 1-DEOXY-D-XYLULOSE 5-PHOSPHATE SYNTHASE | CELL BIOLOGY | STEADY-STATE TREATMENT | SUBSTRATE-BINDING | BIOPHYSICS | BIOSYNTHESIS | PLANTS | SYSTEMS BIOLOGY | Enzymes - chemistry | Oxidoreductases - antagonists & inhibitors | Plasmodium falciparum - enzymology | Erythritol - analogs & derivatives | Models, Chemical | Phosphotransferases (Alcohol Group Acceptor) - chemistry | Oxidoreductases - chemistry | Terpenes - metabolism | Computer Simulation | Enzyme Inhibitors - chemistry | Plasmodium falciparum - metabolism | Protozoan Proteins - chemistry | Erythritol - metabolism | Phosphorus-Oxygen Lyases - chemistry | Transferases - antagonists & inhibitors | Escherichia coli Proteins - antagonists & inhibitors | Aldose-Ketose Isomerases - chemistry | Escherichia coli - enzymology | Transferases - chemistry | Biosynthetic Pathways | Multienzyme Complexes - antagonists & inhibitors | Multienzyme Complexes - chemistry | Phosphotransferases (Alcohol Group Acceptor) - antagonists & inhibitors | Algorithms | Models, Biological | Kinetics | Aldose-Ketose Isomerases - antagonists & inhibitors | Escherichia coli Proteins - chemistry | Phosphorus-Oxygen Lyases - antagonists & inhibitors | Phosphates | Plasmodium falciparum | Enzymes | Metabolites | Analysis | Phytochemistry | Physiological aspects | Models | Sugars | Monosaccharides | Index Medicus
Journal Article
Journal Article
Journal of Integrative Agriculture, ISSN 2095-3119, 03/2019, Volume 18, Issue 3, pp. 644 - 655
The methylerythritol phosphate pathway is responsible for the biosynthesis of terpenoids, the largest class of secondary metabolites. Although the structures... 
methylerythritol phosphate pathway | biological control | transcription | Bacillus subtilis | DISTINCT PATHWAYS | ESCHERICHIA-COLI | 4-PHOSPHATE | HOMOTERPENES | TRANSFER-RNA SYNTHETASE | ISOPRENOID BIOSYNTHESIS | 5-PHOSPHATE | AGRICULTURE, MULTIDISCIPLINARY | BINDING | NONMEVALONATE PATHWAY | RICE
Journal Article
02/2012
The development of new drugs is one strategy for malaria control. Biochemical pathways localised in the apicoplast of the parasite, such as the synthesis of... 
methylerythritol phosphate (MEP) pathway | Plasmodium falciparum | isoprenoids
Web Resource
The Plant Journal, ISSN 0960-7412, 10/2008, Volume 56, Issue 1, pp. 86 - 100
The first step of the plastidial methylerythritol phosphate (MEP) pathway is catalyzed by two isoforms of 1‐deoxy‐ d‐ xylulose 5‐phosphate synthase (DXS1 and... 
isoprenoid biosynthesis | transcriptome profiling | methylerythritol phosphate pathway | mycorradicin | RNAi | arbuscular mycorrhiza | Methylerythritol phosphate pathway | Transcriptome profiling | Mycorradicin | Isoprenoid biosynthesis | Arbuscular mycorrhiza | METHYLERYTHRITOL PHOSPHATE-PATHWAY | PLASTID REORGANIZATION | 1-DEOXY-D-XYLULOSE 5-PHOSPHATE SYNTHASE | PLANT SCIENCES | YELLOW PIGMENT | VICIA-HIRSUTA | CONTAINING CELLS | MEDICAGO-TRUNCATULA | ROOT-NODULES | ISOPENTENYL DIPHOSPHATE | Medicago truncatula - genetics | Erythritol - analogs & derivatives | Oligonucleotide Array Sequence Analysis | Genes, Plant | Genomic Library | Plant Roots - genetics | Medicago truncatula - microbiology | Transferases - genetics | Terpenes - metabolism | RNA Interference | Isoenzymes - metabolism | Transferases - metabolism | Erythritol - metabolism | Plant Proteins - metabolism | Medicago truncatula - enzymology | Symbiosis | Transformation, Genetic | Promoter Regions, Genetic | Plants, Genetically Modified - genetics | Isoenzymes - genetics | Plants, Genetically Modified - enzymology | RNA, Plant - genetics | Plant Roots - microbiology | Reverse Transcriptase Polymerase Chain Reaction | Carotenoids - biosynthesis | Plant Proteins - genetics | Phenotype | Plants, Genetically Modified - microbiology | Sugar Phosphates - metabolism | Mycorrhizae - metabolism | Plant Roots - enzymology | Genetic research | Plant genetics | Phosphates | Genetics | Catalysis | Transgenic plants | Botany | Index Medicus
Journal Article
by Lang, C and Xi, J
Russian Journal of Plant Physiology, ISSN 1021-4437, 3/2016, Volume 63, Issue 2, pp. 293 - 299
Journal Article