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Chemosphere, ISSN 0045-6535, 12/2018, Volume 212, pp. 915 - 926
PM exposure is strongly linked to cardiac disease. Subtle epigenetic or transcriptional alterations induced by PM might contribute to pathogenesis and disease... 
Methylome | Gene | Cardiac disease | Transcriptome
Journal Article
NATURE, ISSN 0028-0836, 01/2017, Volume 541, Issue 7637, pp. 371 - 371
Internal bases in mRNA can be subjected to modifications that influence the fate of mRNA in cells. One of the most prevalent modified bases is found at the 5'... 
DEMETHYLASE | METHYLOME | N-6-METHYLADENOSINE | ALKBH5 | PROTEIN | DATABASE | MULTIDISCIPLINARY SCIENCES | ARGONAUTE | CELL | SEQ | CLIP
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2019, Volume 1870, pp. 69 - 79
Journal Article
Journal of Autoimmunity, ISSN 0896-8411, 06/2013, Volume 43, pp. 78 - 84
Systemic lupus erythematosus is an autoimmune disease characterized by multi-system involvement and autoantibody production. Abnormal T cell DNA methylation... 
Lupus | DNA methylation | Methylome | Naïve CD4+ T cells | Type-I interferon
Journal Article
Development, ISSN 0950-1991, 2017, pp. 1 - 56
Mouse embryonic stem (ES) cells are locked into self-renewal by shielding from inductive cues. Release from this ground state in minimal conditions offers a... 
methylome | Rex1 | ES cells | pluripotency | transcriptome | epiblast
Journal Article
NATURE, ISSN 0028-0836, 11/2017, Volume 551, Issue 7679, pp. 251 - 251
Modifications on mRNA offer the potential of regulating mRNA fate post-transcriptionally. Recent studies suggested the widespread presence of... 
MAPPING REVEALS | METHYLATION | METHYLTRANSFERASE | DNA | MULTIDISCIPLINARY SCIENCES | MOUSE EMBRYOS | PSEUDOURIDYLATION | HEREDITARY OPTIC NEUROPATHY | DYNAMIC N-1-METHYLADENOSINE METHYLOME | EXPRESSION | SEQ
Journal Article
Nature Methods, ISSN 1548-7091, 2014, Volume 11, Issue 8, pp. 817 - 820
We report a single-cell bisulfite sequencing (scBS-seq) method that can be used to accurately measure DNA methylation at up to 48.4% of CpG sites. Embryonic... 
METHYLATION LANDSCAPE | METHYLOME | RNA-SEQ | DNA | EMBRYONIC STEM-CELLS | BIOCHEMICAL RESEARCH METHODS | PLURIPOTENCY | TISSUES | DNA Methylation | Mice | Animals | Genome | Epigenesis, Genetic | Sulfites - chemistry | Measurement | Epigenetic inheritance | Nucleotide sequencing | Observations | Methylation | Methods | DNA sequencing | DNA methylation | Cell culture
Journal Article
Developmental Cell, ISSN 1534-5807, 05/2018, Volume 45, Issue 3, pp. 406 - 416.e3
DNA methylation on -adenine (6mA) has recently been found to be a potentially epigenetic mark in several unicellular and multicellular eukaryotes. However, its... 
Arabidopsis thaliana | transcription | N6-adenine | epigenetic mark | DNA methylation | methylome | 6mA | adenine
Journal Article
by Hoadley, Katherine A and Yau, Christina and Hinoue, Toshinori and Wolf, Denise M and Wolf, Gregory and Lazar, Alexander J and Drill, Esther and Shen, Ronglai and Shen, Hui and Taylor, Alison M and Taylor, Barry S and Cherniack, Andrew D and Thorsson, Vesteinn and Thorsson, Vésteinn and Akbani, Rehan and Bowlby, Reanne and Wong, Tina and Wong, Christopher K and Wiznerowicz, Maciej and Sanchez-Vega, Francisco and Robertson, A. Gordon and Schneider, Barbara G and Lawrence, Michael S and Noushmehr, Houtan and Malta, Tathiane M and Caesar-Johnson, Samantha J and Demchok, John A and Felau, Ina and Kasapi, Melpomeni and Ferguson, Martin L and Hutter, Carolyn M and Sofia, Heidi J and Tarnuzzer, Roy and Wang, Jing and Wang, Linghua and Wang, Timothy and Wang, Min and Wang, Jioajiao and Wang, Zhining and Yang, Liming and Yang, Ju Dong and Yang, Ian and Yang, Hannah and Zenklusen, Jean C and Zhang, Hailei and Zhang, Wei and Zhang, Jiashan (Julia) and Zhang, Lizhi and Zhang, Jiexin and Zhang, Hongxin and Zhang, Hongzheng and Chudamani, Sudha and Liu, Wenbin and Liu, Jia and Liu, Yuexin and Liu, Xiuping and Lolla, Laxmi and Naresh, Rashi and Pihl, Todd and Sun, Qiang and Sun, Yichao and Wan, Yunhu and Wu, Ye and Cho, Juok and DeFreitas, Timothy and Frazer, Scott and Gehlenborg, Nils and Getz, Gad and Heiman, David I and Kim, Jaegil and Lin, Pei and Meier, Sam and Noble, Michael S and Saksena, Gordon and Voet, Doug and Bernard, Brady and Chambwe, Nyasha and Dhankani, Varsha and Knijnenburg, Theo and Kramer, Roger and Leinonen, Kalle and Miller, Michael and Miller, Judy and Miller, Christopher A and Reynolds, Sheila and Shmulevich, Ilya and Broom, Bradley M and Hegde, Apurva M and Ju, Zhenlin and Kanchi, Rupa S and Korkut, Anil and Li, Wei and Li, Jun and Liang, Han and Ling, Shiyun and Lu, Yiling and Mills, Gordon B and Ng, Kwok-Shing and Rao, Arvind and Ryan, Michael and ... and Cancer Genome Atlas Network
Cell, ISSN 0092-8674, 04/2018, Volume 173, Issue 2, pp. 291 - 304.e6
We conducted comprehensive integrative molecular analyses of the complete set of tumors in The Cancer Genome Atlas (TCGA), consisting of approximately 10,000... 
genome | organs | tissues | transcriptome | methylome | cancer | cell-of-origin | TCGA | proteome | subtypes | INTEGRATED GENOMIC CHARACTERIZATION | ACCURATE | SIMILARITIES | BIOCHEMISTRY & MOLECULAR BIOLOGY | UNKNOWN PRIMARY | SIGNATURE | BREAST | DISCOVERY | CELL BIOLOGY
Journal Article
Epigenetics and Chromatin, ISSN 1756-8935, 06/2016, Volume 9, Issue 1, p. 26
DNA methylation is an epigenetic modification that plays an important role in regulating gene expression and therefore a broad range of biological processes... 
Bisulfite sequencing | RRBS | DNA methylation | WGBS | Hydroxymethylation | Methylome | Single-cell | SINGLE-BASE-RESOLUTION | HIGH-THROUGHPUT | MAMMALIAN DEVELOPMENT | CPG METHYLATION | BISULFITE SEQUENCING DATA | BREAST-CANCER | ANALYSIS PIPELINE | GENETICS & HEREDITY | MEDIP-SEQ | METHYLOME ANALYSIS | CYTOSINE METHYLATION | Epigenetic inheritance | Research | Gene expression | Methylation | Analysis | Genomics
Journal Article
TRENDS IN CELL BIOLOGY, ISSN 0962-8924, 02/2018, Volume 28, Issue 2, pp. 113 - 127
N-6-Methyladenosine (m(6)A) is the most prevalent post-transcriptional modification of eukaryotic mRNA and long noncoding RNA. m(6)A mediates its effects... 
MESSENGER-RNA METHYLATION | RECOGNITION | STRUCTURAL BASIS | EMBRYONIC STEM-CELLS | YTH DOMAIN | SEX DETERMINATION | NUCLEAR-RNA | DYNAMIC N-1-METHYLADENOSINE METHYLOME | TRANSLATION | REVEALS | CELL BIOLOGY
Journal Article
CELL RESEARCH, ISSN 1001-0602, 05/2017, Volume 27, Issue 5, pp. 606 - 625
5-methylcytosine (m(5)C) is a post-transcriptional RNA modification identified in both stable and highly abundant tRNAs and rRNAs, and in mRNAs. However, its... 
mRNA export | METHYLATION | PROTEIN | ALYREF | NSUN2 | NUCLEAR EXPORT | PSEUDOURIDYLATION | DYNAMIC N-1-METHYLADENOSINE METHYLOME | TRANSLATION | MAMMALIAN NUCLEI | CELL BIOLOGY | NONCODING RNA | MA RNA | SEQUENCE
Journal Article
Molecular Plant, ISSN 1674-2052, 03/2019, Volume 12, Issue 3, pp. 438 - 446
Single-cell bisulfite sequencing (scBS-seq) was developed to assess DNA methylation heterogeneity in human and mouse. However, the reads are under-represented... 
reprogramming | single-cell methylome | whole-genome amplification | DNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | SITES | METHYLOME LANDSCAPES | GENOME | PLANT SCIENCES | Nucleotide sequencing | Methylation | Analysis | Methods | DNA sequencing
Journal Article
TRENDS IN GENETICS, ISSN 0168-9525, 06/2017, Volume 33, Issue 6, pp. 380 - 390
Modifications in mRNA constitute ancient mechanisms to regulate gene expression post-transcriptionally. N-6-methyladenosine (m(6)A) is the most prominent mRNA... 
MAPPING REVEALS | TRANSLATION EFFICIENCY | STRUCTURAL BASIS | EMBRYONIC STEM-CELLS | MAMMALIAN RNA | GENETICS & HEREDITY | YTH DOMAIN | N-6-METHYLADENOSINE MODIFICATION | SEX DETERMINATION | NUCLEAR-RNA | DYNAMIC N-1-METHYLADENOSINE METHYLOME
Journal Article