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1. Full Text The Brazilian Zika virus strain causes birth defects in experimental models
by Cugola, Fernanda R and Fernandes, Isabella R and Russo, Fabiele B and Freitas, Beatriz C and Dias, Joaõ L. M and Guimarães, Katia P and Benazzato, Cecília and Almeida, Nathalia and Pignatari, Graciela C and Romero, Sarah and Polonio, Carolina M and Cunha, Isabela and Freitas, Carla L and Brandaõ, Wesley N and Rossato, Cristiano and Andrade, David G and Faria, Daniele De P and Garcez, Alexandre T and Buchpigel, Carlos A and Braconi, Carla T and Mendes, Erica and Sall, Amadou A and Zanotto, Paolo M. De A and Peron, Jean Pierre S and Muotri, Alysson R and Beltrao-Braga, Patricia C. B. B
Nature, ISSN 0028-0836, 05/2016, Volume 534, Issue 7606, pp. 267 - 271
Zika virus (ZIKV) is an arbovirus belonging to the genus Flavivirus (family Flaviviridae) and was first described in 1947 in Uganda following blood analyses of... 
PLURIPOTENT STEM-CELLS | INFECTION | MULTIDISCIPLINARY SCIENCES | BRAIN | ORGANOIDS | GROWTH | Cell Proliferation | Brain - virology | Autophagy | Microcephaly - epidemiology | Microcephaly - virology | Zika Virus Infection - virology | Microcephaly - pathology | Zika Virus Infection - complications | Female | Fetus - virology | Brazil - epidemiology | Zika Virus - pathogenicity | Disease Models, Animal | Fetal Growth Retardation - virology | Organoids - pathology | Zika Virus Infection - pathology | Neural Stem Cells - virology | Neural Stem Cells - pathology | Fetal Growth Retardation - pathology | Pregnancy | Animals | Zika Virus Infection - epidemiology | Microcephaly - etiology | Brain - pathology | Mice | Placenta - virology | Apoptosis | Organoids - virology | Microcephaly | Risk factors | Brain | Placenta | Neurons | Zika virus | Birth defects | Viral infections | Index Medicus
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2. Mikrozephalie
by Wissmüller, Hermann F and Koch, Gerhard
1975, Volume 5., 217
Microcephaly | Bibliography
Book
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3. Full Text Zika and the Risk of Microcephaly
by Johansson, Michael A and Mier-y-Teran-Romero, Luis and Reefhuis, Jennita and Gilboa, Suzanne M and Hills, Susan L
The New England Journal of Medicine, ISSN 0028-4793, 07/2016, Volume 375, Issue 1, pp. 1 - 4
An analysis of data from Brazil reveals a strong association between the risk of microcephaly in a newborn and the risk of Zika virus infection during the... 
MEDICINE, GENERAL & INTERNAL | VIRUS | Pregnancy | Microcephaly - embryology | Zika Virus Infection - epidemiology | Disease Outbreaks | Pregnancy Complications, Infectious - epidemiology | Humans | Zika Virus | Zika Virus Infection - complications | Female | Microcephaly - epidemiology | Microcephaly - virology | Brazil - epidemiology | Microcephaly | Pregnant women | Health aspects | Risk factors | Brain | Microencephaly | Data processing | Birth defects | Zika virus | Health risk assessment | Viral infections | Index Medicus | Abridged Index Medicus
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4. Full Text Zika Virus Disrupts Neural Progenitor Development and Leads to Microcephaly in Mice
by Li, Cui and Xu, Dan and Xu, Zhiheng and Ye, Qing and Hong, Shuai and Jiang, Yisheng and Liu, Xinyi and Zhang, Nana and Shi, Lei and Qin, Cheng-Feng
Cell Stem Cell, ISSN 1934-5909, 07/2016, Volume 19, Issue 1, pp. 120 - 126
The link between Zika virus (ZIKV) infection and microcephaly has raised urgent global alarm. The historical African ZIKV MR766 was recently shown to infect... 
STEM | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Cell Cycle - genetics | Brain - embryology | Microcephaly - genetics | Brain - virology | Immunity | Microcephaly - virology | Cell Differentiation - genetics | Zika Virus Infection - virology | Microcephaly - immunology | Cell Death - genetics | Microcephaly - pathology | Embryo, Mammalian - virology | Cell Lineage - genetics | Embryo, Mammalian - pathology | Zika Virus Infection - pathology | Neural Stem Cells - virology | Zika Virus - physiology | Gene Expression Regulation | Neural Stem Cells - pathology | Mice, Inbred ICR | Animals | Zika Virus Infection - genetics | Virus Replication | Embryo, Mammalian - immunology | Brain - pathology | Zika Virus Infection - immunology | Index Medicus
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5. Full Text Zika Virus Associated with Microcephaly
by Mlakar, Jernej and Korva, Misa and Tul, Nataša and Popović, Mara and Poljšak-Prijatelj, Mateja and Mraz, Jerica and Kolenc, Marko and Resman Rus, Katarina and Vesnaver Vipotnik, Tina and Fabjan Vodušek, Vesna and Vizjak, Alenka and Pižem, Jože and Petrovec, Miroslav and Avšič Županc, Tatjana
The New England Journal of Medicine, ISSN 0028-4793, 03/2016, Volume 374, Issue 10, pp. 951 - 958
Zika virus is an emerging infectious disease that is spreading rapidly through the Americas. A major concern is the association with birth defects, especially... 
MEDICINE, GENERAL & INTERNAL | Brain - embryology | Zika Virus - genetics | Humans | Brain - virology | Phylogeny | Microcephaly - virology | Pregnancy Trimester, Third | Microcephaly - pathology | Zika Virus Infection - complications | Adult | Female | Abortion, Therapeutic | Genome, Viral | Zika Virus Infection - pathology | Fetal Diseases - diagnostic imaging | Infectious Disease Transmission, Vertical | Microcephaly - diagnostic imaging | Zika Virus - isolation & purification | Reverse Transcriptase Polymerase Chain Reaction | Fetal Diseases - virology | Pregnancy | Zika Virus Infection - transmission | Ultrasonography, Prenatal | Fetal Diseases - pathology | Brain - pathology | Polymerase chain reaction | Usage | Care and treatment | Ultrasound imaging | Research | Fetal brain | Microcephaly | Brain | Hydrocephalus | Fetuses | Cortex | Birth defects | Zika virus | Genomes | Gestation | Substantia alba | Electron microscopy | Microencephaly | Placenta | Maternal & child health | Autopsy | Ultrasonography | Neurological disorders | Viral infections | Index Medicus | Abridged Index Medicus
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6. Full Text Zika Virus Disrupts Phospho-TBK1 Localization and Mitosis in Human Neuroepithelial Stem Cells and Radial Glia
by Onorati, Marco and Li, Zhen and Li, Mingfeng and Liu, Fuchen and Sousa, André M.M and Nakagawa, Naoki and Dell’Anno, Maria Teresa and Gulden, Forrest O and Pochareddy, Sirisha and Tebbenkamp, Andrew T.N and Han, Wenqi and Pletikos, Mihovil and Gao, Tianliuyun and Gao, Xiao-Bing and Zhu, Ying and Bichsel, Candace and Varela, Luis and Szigeti-Buck, Klara and Lisgo, Steven and Zhang, Yalan and Testen, Anze and Mlakar, Jernej and Popovic, Mara and Flamand, Marie and Strittmatter, Stephen M and Kaczmarek, Leonard K and Anton, E.S and Horvath, Tamas L and Lindenbach, Brett D and Sestan, Nenad
Cell Reports, ISSN 2211-1247, 09/2016, Volume 16, Issue 10, pp. 2576 - 2592
The mechanisms underlying Zika virus (ZIKV)-related microcephaly and other neurodevelopment defects remain poorly understood. Here, we describe the derivation... 
NEURAL PROGENITORS | LONG-TERM | HUMAN BRAIN | ADAPTER | CENTRAL-NERVOUS-SYSTEM | INFECTION | MICE | BINDING KINASE 1 | ORGANOIDS | INNATE IMMUNITY | CELL BIOLOGY | Neocortex - pathology | Neurons - pathology | Transcription, Genetic - drug effects | Brain - embryology | Neuroglia - ultrastructure | Neuroglia - pathology | Humans | Brain - virology | Centrosome - drug effects | Gene Expression Profiling | Microcephaly - virology | Neural Stem Cells - ultrastructure | Zika Virus Infection - virology | Neural Stem Cells - immunology | Neuroepithelial Cells - immunology | Neuroprotective Agents - pharmacology | Spinal Cord - pathology | Microcephaly - pathology | Neuroepithelial Cells - virology | Nucleosides - pharmacology | Fetus - virology | Cell Death - drug effects | Phosphorylation - drug effects | Neurons - drug effects | Protein-Serine-Threonine Kinases - metabolism | Zika Virus - pathogenicity | Proto-Oncogene Proteins - metabolism | Zika Virus - ultrastructure | Neurons - virology | Virus Replication - drug effects | Neuroepithelial Cells - ultrastructure | Immunity, Innate - drug effects | Zika Virus Infection - pathology | Neural Stem Cells - virology | Zika Virus - physiology | Zika Virus - drug effects | Mitochondria - metabolism | Mitochondria - drug effects | Receptor Protein-Tyrosine Kinases - metabolism | Neural Stem Cells - enzymology | Centrosome - metabolism | Mitosis - drug effects | Brain - pathology | Protein Kinase Inhibitors - pharmacology | Neuroglia - virology | Neuroepithelial Cells - drug effects | Index Medicus | Neurons/pathology | Zika Virus/pathogenicity | Mitochondria/metabolism | Virus Replication/drug effects | Microcephaly/pathology | Neurons/drug effects | Protein-Serine-Threonine Kinases/metabolism | Neural Stem Cells/immunology | Neuroglia/ultrastructure | Neuroepithelial Cells/drug effects | Neuroepithelial Cells/virology | Life Sciences | Brain/pathology | Zika Virus/drug effects | Brain/embryology | Mitochondria/drug effects | Fetus/virology | Neocortex/pathology | Neuroglia/pathology | Cell Death/drug effects | Mitosis/drug effects | Transcription, Genetic/drug effects | Nucleosides/pharmacology | Neural Stem Cells/enzymology | Neural Stem Cells/ultrastructure | Neuroepithelial Cells/ultrastructure | Receptor Protein-Tyrosine Kinases/metabolism | Microcephaly/virology | Proto-Oncogene Proteins/metabolism | Neuroprotective Agents/pharmacology | Zika Virus/ultrastructure | Neuroepithelial Cells/immunology | Brain/virology | Immunity, Innate/drug effects | Spinal Cord/pathology | Zika Virus/physiology | Neuroglia/virology | Microbiology and Parasitology | Zika Virus Infection/pathology | Neurons/virology | Zika Virus Infection/virology | Neural Stem Cells/virology | Centrosome/drug effects | Protein Kinase Inhibitors/pharmacology | Centrosome/metabolism | Phosphorylation/drug effects
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7. Full Text Zika Virus and Birth Defects — Reviewing the Evidence for Causality
by Rasmussen, Sonja A and Jamieson, Denise J and Honein, Margaret A and Petersen, Lyle R
The New England Journal of Medicine, ISSN 0028-4793, 05/2016, Volume 374, Issue 20, pp. 1981 - 1987
Zika virus has spread rapidly throughout the Americas over the past year. In this report, CDC authors determine that the evidence level has exceeded the... 
MEDICINE, GENERAL & INTERNAL | STATES | TERATOGEN UPDATE | INFECTION | OUTBREAK | ASSOCIATION | BRAZIL | BRAIN | Humans | Zika Virus | Zika Virus Infection - complications | Causality | Microcephaly - epidemiology | Microcephaly - virology | Brazil - epidemiology | Pregnancy | Complications and side effects | Microcephaly | Risk factors | Brain | Microencephaly | Congenital defects | Prenatal development | Birth defects | Zika virus | Prenatal experience | Viral infections | Index Medicus | Abridged Index Medicus
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8. Full Text Association between Zika virus infection and microcephaly in Brazil, January to May, 2016: preliminary report of a case-control study
by de Araújo, Thalia Velho Barreto, Dr and Rodrigues, Laura Cunha, Prof and de Alencar Ximenes, Ricardo Arraes, Prof and de Barros Miranda-Filho, Demócrito, PhD and Montarroyos, Ulisses Ramos, PhD and de Melo, Ana Paula Lopes, MSc and Valongueiro, Sandra, PhD and de Albuquerque, Maria de Fátima Pessoa Militão, PhD and Souza, Wayner Vieira, PhD and Braga, Cynthia, PhD and Filho, Sinval Pinto Brandão, PhD and Cordeiro, Marli Tenório, PhD and Vazquez, Enrique, PhD and Di Cavalcanti Souza Cruz, Danielle, MD and Henriques, Cláudio Maierovitch Pessanha, MSc and Bezerra, Luciana Caroline Albuquerque, MSc and da Silva Castanha, Priscila Mayrelle, PhD and Dhalia, Rafael, PhD and Marques-Júnior, Ernesto Torres Azevedo, PhD and Martelli, Celina Maria Turchi, Prof and State Health Department of Pernambuco and Brazilian Ministry of Health and Pan American Health Organization and investigators from the Microcephaly Epidemic Research Group and Instituto de Medicina Integral Professor Fernando Figueira
Lancet Infectious Diseases, The, ISSN 1473-3099, 2016, Volume 16, Issue 12, pp. 1356 - 1363
Summary Background The microcephaly epidemic, which started in Brazil in 2015, was declared a Public Health Emergency of International Concern by WHO in 2016.... 
Infectious Disease | INFECTIOUS DISEASES | AMERICA | FETAL | Neuroimaging | Pregnancy Complications, Infectious - virology | Prospective Studies | Pregnancy Complications, Infectious - epidemiology | Zika Virus Infection - congenital | Zika Virus Infection - pathology | Humans | Risk Factors | Zika Virus - isolation & purification | Gestational Age | Microcephaly - epidemiology | Microcephaly - virology | Pregnancy Complications, Infectious - pathology | Case-Control Studies | Pregnancy | Zika Virus Infection - diagnosis | Zika Virus Infection - epidemiology | Microcephaly - pathology | Female | Brazil - epidemiology | Virus diseases | Epidemics | Health aspects | Epidemiology | Public health | Medical research | Analysis | Dengue viruses | Medicine, Experimental | Risk factors | Parent educational background | Medical imaging | Menstruation | Zika virus | Birth defects | Infections | Microcephaly | Studies | Hypotheses | Health risk assessment | Age | Index Medicus
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9. Full Text Zika virus cell tropism in the developing human brain and inhibition by azithromycin
by Hanna Retallack and Elizabeth Di Lullo and Carolina Arias and Kristeene A. Knopp and Matthew T. Laurie and Carmen Sandoval-Espinosa and Walter R. Mancia Leon and Robert Krencik and Erik M. Ullian and Julien Spatazza and Alex A. Pollen and Caleigh Mandel-Brehm and Tomasz J. Nowakowski and Arnold R. Kriegstein and Joseph L. DeRisi
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2016, Volume 113, Issue 50, pp. 14408 - 14413
The rapid spread of Zika virus (ZIKV) and its association with abnormal brain development constitute a global health emergency. Congenital ZIKV infection... 
Cortical development | Zika virus | Microcephaly | Azithromycin | microcephaly | STEM-CELLS | NEOCORTEX | MODELS | SCREEN | MULTIDISCIPLINARY SCIENCES | azithromycin | INFECTION | MICE | cortical development | Zika Virus Infection - drug therapy | Brain - embryology | Cytopathogenic Effect, Viral - drug effects | Neuroglia - pathology | Humans | Receptor Protein-Tyrosine Kinases - physiology | Brain - virology | Virus Internalization - drug effects | Neuroglia - drug effects | Microbial Sensitivity Tests | Microcephaly - embryology | Viral Tropism - drug effects | Microcephaly - pathology | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Female | Infant, Newborn | Microcephaly - drug therapy | Zika Virus - pathogenicity | Viral Tropism - physiology | Cell Line | Proto-Oncogene Proteins - antagonists & inhibitors | Virus Replication - drug effects | Zika Virus Infection - pathology | Zika Virus - physiology | Zika Virus - drug effects | Azithromycin - pharmacology | Pregnancy | Zika Virus Infection - embryology | Proto-Oncogene Proteins - physiology | Brain - pathology | Neuroglia - virology | Tropisms | Brain | Health aspects | Antibiotics | Neurons | Stem cells | Index Medicus | Biological Sciences
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10. Full Text Zika virus in Brazil and macular atrophy in a child with microcephaly
by Ventura, Camila V and Maia, Mauricio and Bravo-Filho, Vasco and Góis, Adriana L and Belfort, Rubens
Lancet, The, ISSN 0140-6736, 2016, Volume 387, Issue 10015, pp. 228 - 228
To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/S0140-6736(16)00006-4 Byline: Camila V Ventura, Mauricio Maia, Vasco... 
Internal Medicine | MEDICINE, GENERAL & INTERNAL | Retinal Diseases - diagnosis | Humans | Zika Virus | Microcephaly - diagnosis | Infant | Male | Microcephaly - virology | Atrophy | Zika Virus Infection - diagnosis | Retinal Diseases - etiology | Microcephaly - etiology | Zika Virus Infection - complications | Female | Brazil - epidemiology | Macula Lutea - pathology | Retinal Diseases - virology | Macular degeneration | Zika virus | Viral infections | Children & youth | Index Medicus | Abridged Index Medicus
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11. Full Text Microcephaly in Infants, Pernambuco State, Brazil, 2015
by and Microcephaly Epidemic Research Group and Microcephaly Epidemic Research Group1
Emerging infectious diseases, ISSN 1080-6040, 06/2016, Volume 22, Issue 6, pp. 1090 - 1093
We studied the clinical characteristics for 104 infants born with microcephaly in the delivery hospitals of Pernambuco State, Brazil, during 2015. Testing is... 
viruses | infants | vector-borne infections | Brazil | disease outbreaks | Zika virus | Microcephaly | History, 21st Century | Humans | Zika Virus | Microcephaly - diagnosis | Infant | Male | Tomography, X-Ray Computed | Pregnancy Complications, Infectious | Microcephaly - epidemiology | Pregnancy | Young Adult | Adolescent | Microcephaly - etiology | Zika Virus Infection - complications | Adult | Female | Seasons | Microcephaly - history | Population Surveillance | Brazil - epidemiology | Infant, Newborn | Infection | Index Medicus | Expedited | Microcephaly in Infants, Pernambuco State, Brazil, 2015 | Dispatch
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12. Full Text Microcephaly
by Arroyo, Hugo A
Medicina (Argentina), ISSN 0025-7680, 09/2018, Volume 78, pp. 94 - 100
Genetic | Acquired microcephaly | Congenital microcephaly | Infectious | Microcephaly
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13. Full Text Stress-induced unfolded protein response contributes to Zika virus-associated microcephaly
by Gladwyn-Ng, Ivan and Cordón-Barris, Lluís and Alfano, Christian and Creppe, Catherine and Couderc, Thérèse and Morelli, Giovanni and Thelen, Nicolas and America, Michelle and Bessières, Bettina and Encha-Razavi, Férechté and Bonnière, Maryse and Suzuki, Ikuo K and Flamand, Marie and Vanderhaeghen, Pierre and Thiry, Marc and Lecuit, Marc and Nguyen, Laurent
Nature Neuroscience, ISSN 1097-6256, 01/2018, Volume 21, Issue 1, pp. 63 - 73
Accumulating evidence support a causal link between Zika virus (ZIKV) infection during gestation and congenital microcephaly. However, the mechanism of... 
MIGRATION | RESISTANCE | CELLS | INFECTION | DEATH | NEUROSCIENCES | Brain - embryology | Embryo, Mammalian | Protein Unfolding | Humans | Brain - virology | Microcephaly - virology | Brain - metabolism | Interferon-alpha - genetics | Microcephaly - prevention & control | Zika Virus Infection - complications | Fetus | Neuroblastoma - pathology | Zika Virus - pathogenicity | Disease Models, Animal | Interferon-alpha - metabolism | Zika Virus Infection - pathology | Mice, Inbred C57BL | Microcephaly - metabolism | Mice, Transgenic | Activating Transcription Factor 3 - metabolism | Nerve Tissue Proteins - metabolism | Animals | Gene Expression Regulation, Viral | Microcephaly - etiology | Brain - pathology | Cell Line, Tumor | Mice | Endoplasmic Reticulum Stress - physiology | Proteins | Cerebral cortex | Physiological aspects | Causes of | Development and progression | Stress (Physiology) | Microcephaly | Health aspects | Conformation | Stresses | Vector-borne diseases | Fetuses | Cortex | Stem cell transplantation | Viruses | Zika virus | Pharmacology | Gestation | Embryos | Neurogenesis | Stress | Defects | Inoculation | Microencephaly | Allografts | Protein folding | Stem cells | Neural stem cells | Endoplasmic reticulum | Apoptosis | Index Medicus | Life Sciences | Microbiology and Parasitology | Virology
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