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Diabetes, ISSN 0012-1797, 02/2013, Volume 62, Issue 2, pp. 313 - 319
Journal Article
Cellular and Molecular Life Sciences, ISSN 1420-682X, 11/2017, Volume 74, Issue 22, pp. 4097 - 4120
In the central nervous system, embryonic and adult neural stem/progenitor cells (NSCs) generate the enormous variety and huge numbers of neuronal and glial... 
Biomedicine, general | Biochemistry, general | Agonists/antagonists | Brain development | Neurogenesis | Glucocorticoid | Cell Biology | Life Sciences | Neurological diseases | Life Sciences, general | Drug targets | Astrogliogenesis | Retinoic acid | PROLIFERATOR-ACTIVATED RECEPTORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | VITAMIN-D-RECEPTOR | ORPHAN RECEPTOR | STEROIDOGENIC FACTOR-I | MINERALOCORTICOID RECEPTOR | CELL BIOLOGY | GLUCOCORTICOID-RECEPTOR | EMBRYONIC STEM-CELLS | CENTRAL-NERVOUS-SYSTEM | RETINOID-X-RECEPTOR | THYROID-HORMONE RECEPTOR | Receptors, Estrogen - metabolism | Receptors, Mineralocorticoid - metabolism | Humans | Receptors, Glucocorticoid - metabolism | Receptors, Calcitriol - metabolism | Neural Stem Cells - cytology | Receptors, Thyroid Hormone - metabolism | Animals | Nervous System Diseases - metabolism | Cell Differentiation | Neural Stem Cells - metabolism | Nervous System Diseases - pathology | Receptors, Cytoplasmic and Nuclear - metabolism | Medical research | Embryonic development | Nervous system diseases | Corticosteroids | Neurons | Homeostasis | Medicine, Experimental | Brain | Spinal cord | Regulators | Pathogenesis | Central nervous system | Nervous system | Glial cells | Nuclear receptors | Orphan nuclear receptors | Neuronal-glial interactions | Embryonic growth stage | Receptors | Embryogenesis | Molecular modelling | Cells (biology) | Stem cells | Neural stem cells | Receptor mechanisms | Aberration | Bile | Structure-function relationships
Journal Article
Circulation, ISSN 0009-7322, 04/2008, Volume 117, Issue 17, pp. 2253 - 2261
Background - In obesity, decreases in adiponectin and increases in proinflammatory adipokines are associated with heart disease. Because adipocytes express... 
Obesity | Adipose tissue | Mineralocorticoid receptor | Diabetes mellitus | Inflammation | Aldosterone | Aldosterone antagonists | MACROPHAGE INFILTRATION | METABOLIC SYNDROME | CARDIAC & CARDIOVASCULAR SYSTEMS | MYOCARDIAL-INFARCTION | aldosterone | adipose tissue | diabetes mellitus | mineralocorticoid receptor | inflammation | INSULIN-RESISTANCE | CARDIOVASCULAR-DISEASE | PERIPHERAL VASCULAR DISEASE | aldosterone antagonists | HEMATOLOGY | TYPE-2 DIABETES-MELLITUS | TRANSCRIPTIONAL REGULATION | obesity | ADIPOSE-TISSUE | Diabetes Mellitus, Experimental - drug therapy | Body Weight | Myocardium - immunology | Obesity - drug therapy | Obesity - immunology | Receptors, Mineralocorticoid - metabolism | Male | PPAR gamma - immunology | Adipose Tissue - immunology | RNA, Messenger - metabolism | Inflammation - complications | Inflammation - drug therapy | Mice, Mutant Strains | Adipokines - genetics | Adiponectin - genetics | Diabetes Mellitus, Experimental - complications | Leptin - immunology | Mineralocorticoid Receptor Antagonists | PPAR gamma - genetics | Obesity - complications | Homeostasis - immunology | Aldosterone - pharmacology | Adipokines - immunology | Inflammation - immunology | Leptin - genetics | 3T3-L1 Cells | Diabetes Mellitus, Experimental - immunology | Animals | Triglycerides - blood | Biomarkers | Mice | Adiponectin - immunology | Adipose Tissue - drug effects
Journal Article
Biochemical Journal, ISSN 0264-6021, 11/2005, Volume 391, Issue 3, pp. 449 - 464
Steroid hormones are important endocrine signalling molecules controlling reproduction, development, metabolism, salt balance and specialized cellular... 
Af1 transactivation domain | Post-translational modification | Steroid receptor | Allosteric regulation | Protein-protein interaction | Protein-nucleic acid interaction | Secondary structure | protein-nucleic acid interaction | RNA-POLYMERASE-II | HUMAN ESTROGEN-RECEPTOR | HUMAN MINERALOCORTICOID RECEPTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | ACTIVATION FUNCTION 1 | AF1 transactivation domain | allosteric regulation | post-translational modification | TRANSCRIPTION FACTOR-TFIIF | steroid receptor | secondary structure | AMINO-TERMINAL DOMAIN | HUMAN ANDROGEN RECEPTOR | HUMAN GLUCOCORTICOID-RECEPTOR | protein-protein interaction | LIGAND-BINDING DOMAIN | HUMAN PROGESTERONE-RECEPTORS | Protein Structure, Tertiary | Animals | Receptors, Steroid - metabolism | Humans | Transcriptional Activation | Models, Molecular | Protein Binding | Protein Processing, Post-Translational | Receptors, Steroid - chemistry | SMRT, silencing mediator of retinoid and thyroid hormone receptor | protein–protein interaction | PSA, prostate-specific antigen | PIC, pre-initiation complex | SRC-1, steroid receptor co-activator 1 | Review | PR, progesterone receptor | HCA, hydrophobic cluster analysis | IF, inhibitory function | protein–nucleic acid interaction | PKB, protein kinase B | FLASH, Fas-associated huge protein | AF, activation function | SC, synergy control | SHR, steroid hormone receptor | TIF2, transcription intermediary factor 2 | GTF, general transcription factor | β, oestrogen receptor α and β respectively | TFE, trifluoroethanol | DBD, DNA-binding domain | ERα | GRIP1, glucocorticoid receptor-interacting protein 1 | TBP, TATA-binding protein | LBD, ligand-binding domain | PIAS, protein inhibitor of activated STAT | TMAO, trimethylamine-N-oxide | NCoR, nuclear receptor co-repressor | MR, mineralocorticoid receptor | NTD, N-terminal domain | GR, glucocorticoid receptor | ERE, oestrogen-response element | FTIR spectroscopy, Fourier-transform infrared spectroscopy | AR, androgen receptor | CBP, CREB (cAMP-response-element-binding protein)-binding protein | MAPK, mitogen-activated protein kinase
Journal Article
Kidney International, ISSN 0085-2538, 06/2018, Volume 93, Issue 6, pp. 1344 - 1355
Acute kidney injury induced by ischemia/reperfusion is an independent risk factor for chronic kidney disease. Macrophage recruitment plays an essential role... 
inflammation | macrophage polarization | ischemic injury | ACUTE KIDNEY INJURY | ACTIVATION | CONTRIBUTE | HYPERKALEMIA | REPAIR | SPIRONOLACTONE | DISEASE | UROLOGY & NEPHROLOGY | POLARIZATION | PLASTICITY | AKI | Receptors, Mineralocorticoid - genetics | Kidney - pathology | Receptors, Mineralocorticoid - metabolism | Macrophages, Peritoneal - pathology | Male | Acute Kidney Injury - genetics | Receptors, Mineralocorticoid - drug effects | Kidney - metabolism | Inflammation Mediators - metabolism | Mineralocorticoid Receptor Antagonists - pharmacology | Macrophages, Peritoneal - drug effects | Reperfusion Injury - genetics | Reperfusion Injury - metabolism | Disease Models, Animal | Kidney - drug effects | Reperfusion Injury - pathology | Signal Transduction | Acute Kidney Injury - pathology | Mice, Inbred C57BL | Cells, Cultured | Receptors, Cell Surface - metabolism | Acute Kidney Injury - prevention & control | Mice, Knockout | Phenotype | Animals | Reperfusion Injury - prevention & control | Fibrosis | Acute Kidney Injury - metabolism | Macrophages, Peritoneal - metabolism | Sus scrofa | Naphthyridines - pharmacology | Plasma | Flow cytometry | CD11b antigen | Phenotypes | Kidneys | Dendritic cells | Cytokines | Smooth muscle | Inflammation | Gene expression | Macrophages | Variance analysis | Interleukin 4 | Cell activation | Reperfusion | Ischemia | Granulocytes | Rodents | Kidney diseases | Growth factors | Life Sciences | Human health and pathology
Journal Article
Molecular Endocrinology, ISSN 0888-8809, 02/2013, Volume 27, Issue 2, pp. 192 - 202
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 2006, Volume 216, Issue 1, pp. 44 - 54
Several pesticides and fungicides commonly used to control agricultural and indoor pests are highly suspected to display endocrine-disrupting effects in... 
Vinclozolin | Mineralocorticoid receptor | Androgen receptor | Glucocorticoid receptor | Estrogen receptors | Progesterone receptor | Fungicide | Reporter cell lines | REPORTER CELL-LINES | glucocorticoid receptor | ANTIANDROGENIC ACTIVITY | MALE-RAT | FUNGICIDE VINCLOZOLIN | PROGESTERONE-RECEPTORS | mineralocorticoid receptor | GENE ASSAYS | vinclozolin | estrogen receptors | progesterone receptor | ENVIRONMENTAL ESTROGENS | IN-VITRO | ENDOCRINE DISRUPTORS | androgen receptor | SEXUAL-DIFFERENTIATION | PHARMACOLOGY & PHARMACY | TOXICOLOGY | reporter cell lines | fungicide | Receptors, Mineralocorticoid - genetics | Androgen Receptor Antagonists | Receptors, Glucocorticoid - antagonists & inhibitors | Luciferases - metabolism | Receptors, Steroid - metabolism | Gene Expression - drug effects | Receptors, Mineralocorticoid - metabolism | Humans | Receptors, Androgen - metabolism | Anilides - chemistry | Tritium | Receptors, Glucocorticoid - metabolism | Receptors, Progesterone - genetics | Receptors, Steroid - antagonists & inhibitors | Receptors, Progesterone - antagonists & inhibitors | Luciferases - genetics | Receptors, Progesterone - metabolism | Dose-Response Relationship, Drug | Dexamethasone - pharmacology | Progesterone Congeners - pharmacology | Metribolone - pharmacology | Mineralocorticoid Receptor Antagonists | Estradiol - pharmacology | Carbamates - pharmacology | Cell Survival - drug effects | Oxazoles - metabolism | Androgen Antagonists - pharmacology | Anilides - metabolism | Aldosterone - pharmacology | Testosterone Congeners - pharmacology | Binding, Competitive - drug effects | Receptors, Androgen - genetics | Receptors, Steroid - genetics | Receptors, Glucocorticoid - genetics | Cell Line, Tumor | Promegestone - pharmacology | Oxazoles - pharmacology | Corticosteroids | Progesterone | Fungicides | Plant metabolites | Estrogen | ANIMALS | ESTROGENS | METABOLITES | FUNGICIDES | GLUCOCORTICOIDS | PROGESTERONE | ERBIUM SULFIDES | 60 APPLIED LIFE SCIENCES | LUCIFERASE | RISK ASSESSMENT | LIGANDS | ANDROGENS | RECEPTORS
Journal Article