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Journal of Clinical Oncology, ISSN 0732-183X, 03/2018, Volume 36, Issue 8, pp. 773 - 779
PurposeNivolumab provides clinical benefit (objective response rate [ORR], 31%; 95% CI, 20.8 to 42.9; disease control rate, 69%; 12-month overall survival... 
CRITERIA | MULTICENTER | MELANOMA | SOLID TUMORS | ONCOLOGY | PD-1 BLOCKADE | OPEN-LABEL | QUALITY-OF-LIFE | DEFICIENCY | GUIDELINE
Journal Article
JOURNAL OF CLINICAL MEDICINE, ISSN 2077-0383, 04/2019, Volume 8, Issue 4, p. 558
The study objective was to assess US physicians' Mismatch Repair/Microsatellite Instability (MMR/MSI) testing practices for metastatic colorectal cancer (mCRC)... 
PATHOGENESIS | MEDICINE, GENERAL & INTERNAL | REPAIR | colorectal cancer | MICROSATELLITE INSTABILITY | microsatellite instability testing | survey | mismatch repair | ONCOLOGY PRACTICE | IMMUNOHISTOCHEMISTRY | mismatch repair/microsatellite instability testing
Journal Article
Cancers, ISSN 2072-6694, 08/2019, Volume 11, Issue 9, p. 1279
Glioblastomas (GBMs) are classified into isocitrate dehydrogenase ( ) mutants and IDH wild-types ( -wt). This study aimed at identifying the mutational assets... 
tumour mutation load | mismatch repair | glioblastoma | IDH wild-type | giant cells | POLE
Journal Article
Journal Article
Journal Article
European Journal of Cancer, ISSN 0959-8049, 11/2017, Volume 86, pp. 266 - 274
Patients treated with chemotherapy for microsatellite unstable (MSI) and/or mismatch repair deficient (dMMR) cancer metastatic colorectal cancer (mCRC) exhibit... 
Microsatellite instability | Mismatch repair | Immunotherapy | Colorectal cancer | Lynch syndrome | BRAF mutation | SURVIVAL | MULTICENTER | METHYLATION | GUIDELINES | ADJUVANT THERAPY | FLUOROURACIL | STAGE-II | COLON-CANCER | ONCOLOGY | Multivariate Analysis | Predictive Value of Tests | Microsatellite Instability | Colorectal Neoplasms - genetics | Colorectal Neoplasms, Hereditary Nonpolyposis - pathology | Humans | Middle Aged | Male | Colorectal Neoplasms - therapy | Colorectal Neoplasms, Hereditary Nonpolyposis - mortality | Colorectal Neoplasms, Hereditary Nonpolyposis - therapy | DNA Methylation | Molecular Diagnostic Techniques | Neoplasm Metastasis | Time Factors | DNA Mismatch Repair | Adult | Female | Retrospective Studies | France | Colorectal Neoplasms - mortality | Diagnosis, Differential | Genetic Predisposition to Disease | Colorectal Neoplasms, Hereditary Nonpolyposis - genetics | Risk Factors | Kaplan-Meier Estimate | Proportional Hazards Models | Treatment Outcome | Heredity | Disease-Free Survival | Phenotype | Pedigree | Proto-Oncogene Proteins B-raf - genetics | MutL Protein Homolog 1 - genetics | Aged | Biomarkers, Tumor - genetics | Mutation | Colorectal Neoplasms - pathology | Genetic aspects | Metastasis | Methylation | Cancer | Identification methods | Liver | Colorectal carcinoma | Medical records | Raf protein | Multivariate analysis | DNA repair | Metastases | Repair | Deoxyribonucleic acid--DNA | Age | Genetic disorders | Microsatellites | Stability | MLH1 protein | Patients | Survival | Molecular chains | Studies | Chemotherapy | Tumors | Life Sciences | Human health and pathology | Hépatology and Gastroenterology
Journal Article
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, ISSN 0147-5185, 04/2012, Volume 36, Issue 4, pp. 560 - 569
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 2003, Volume 112, Issue 12, pp. 1887 - 1894
  Chronic infection and associated inflammation are key contributors to human carcinogenesis. Ulcerative colitis (UC) is an oxyradical overload disease and is... 
Journal Article
American Journal of Ophthalmology, ISSN 0002-9394, 2014, Volume 157, Issue 3, pp. 640 - 647.e2
Purpose To characterize mismatch repair protein expression and the role of DNA repair abnormalities in sebaceous carcinomas of the ocular adnexa. Design... 
Ophthalmology | COLORECTAL CARCINOMAS | PROTEIN-DEFICIENCY | NEOPLASMS | MUIR-TORRE-SYNDROME | FREQUENCY | OPHTHALMOLOGY | LYNCH SYNDROME | MUTATIONS | TUMORS | EXPRESSION | IMMUNOHISTOCHEMISTRY | MutL Protein Homolog 1 | Microsatellite Instability | Adenocarcinoma, Sebaceous - metabolism | Humans | Middle Aged | DNA Repair Enzymes - genetics | Male | DNA Mismatch Repair - genetics | MutS Homolog 2 Protein - metabolism | Immunoenzyme Techniques | DNA-Binding Proteins - metabolism | DNA Repair Enzymes - metabolism | Aged, 80 and over | Adult | Female | Eyelid Neoplasms - genetics | Mismatch Repair Endonuclease PMS2 | Retrospective Studies | Nuclear Proteins - genetics | Adenocarcinoma, Sebaceous - pathology | Sebaceous Gland Neoplasms - genetics | Adenosine Triphosphatases - metabolism | Nuclear Proteins - metabolism | MutS Homolog 2 Protein - genetics | Eyelid Neoplasms - pathology | DNA-Binding Proteins - genetics | Eyelid Neoplasms - metabolism | Sebaceous Gland Neoplasms - pathology | Adaptor Proteins, Signal Transducing - genetics | Adenosine Triphosphatases - genetics | Aged | Adaptor Proteins, Signal Transducing - metabolism | Adenocarcinoma, Sebaceous - genetics | Sebaceous Gland Neoplasms - metabolism | DNA | Genetic aspects | Cancer | Proteins | Pathology | Cloning | Colorectal cancer | Mutation | Patients | Age | Deoxyribonucleic acid--DNA | Tumors
Journal Article
Bulletin du Cancer, ISSN 0007-4551, 02/2019, Volume 106, Issue 2, pp. 137 - 142
Microsatellite instability (MSI) is a molecular indicator of defective DNA mismatch repair (dMMR) and is observed in approximately 5% of metastatic colorectal... 
BRAF | Immune checkpoint | Microsatellite instability | Mismatch repair | Colorectal cancer | Lynch syndrome | ONCOLOGY | PD-1 BLOCKADE | RESISTANCE | MUTATIONS | TUMORS
Journal Article
Cancer Research, ISSN 0008-5472, 12/1995, Volume 55, Issue 24, pp. 6063 - 6070
The instability of short repetitive sequences in tumor DNA can result from defective repair of replication errors due to mutations in any of several genes... 
NONPOLYPOSIS COLON-CANCER