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81. Full Text Mitochondrial Dysfunction in Airway Disease
by Prakash, Y.S and Pabelick, Christina M and Sieck, Gary C
Chest, ISSN 0012-3692, 09/2017, Volume 152, Issue 3, pp. 618 - 626
remodeling | asthma | metabolism | oxidative stress | COPD | Respiratory System | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Reactive Oxygen Species | Oxidative Stress | Humans | Lung Diseases - physiopathology | Lung Diseases - therapy | Mitochondria - physiology | Lung Diseases - etiology | Apoptosis | Physiology, Pathological | Lung diseases, Obstructive | Care and treatment | Usage | Mitochondrial diseases | Risk factors | Index Medicus | Abridged Index Medicus | PM, plasma membrane | Mfn, mitofusin | CS, cigarette smoke | DAMP, damage-associated molecular pattern | Drp1, dynamin-related protein 1 | Fis1, fission 1 | Opa1, optic atrophy protein 1 | mtDNA, mitochondrial DNA | ROS, reactive oxygen species | ASM, airway smooth muscle | ATP, adenosine triphosphate | ER, endoplasmic reticulum | Translating Basic Research Into Clinical Practice
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82. Full Text Oxidative stress, cardiolipin and mitochondrial dysfunction in nonalcoholic fatty liver disease
by Giuseppe Paradies Valeria Paradies Francesca M Ruggiero Giuseppe Petrosillo
World journal of gastroenterology : WJG, ISSN 1007-9327, 2014, Volume 20, Issue 39, pp. 14205 - 14218
stress | Oxidative | Cardiolipin | Mitochondrial | bioener | Antioxidants | Oxidative stress | Nonalcoholic fatty liver disease | Mitochondrial bioenergetics | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Mitochondrial Diseases - pathology | Non-alcoholic Fatty Liver Disease - pathology | Protein Carbonylation | Liver - pathology | Reactive Oxygen Species - metabolism | Mitochondria, Liver - metabolism | Humans | Mitochondrial Diseases - metabolism | Liver - physiopathology | Liver - drug effects | Mitochondrial Diseases - drug therapy | DNA, Mitochondrial - metabolism | Liver - metabolism | Cardiolipins - metabolism | Non-alcoholic Fatty Liver Disease - metabolism | Non-alcoholic Fatty Liver Disease - physiopathology | Non-alcoholic Fatty Liver Disease - drug therapy | Mitochondria, Liver - drug effects | Antioxidants - therapeutic use | Animals | Electron Transport Chain Complex Proteins - metabolism | DNA Damage | Oxidative Stress - drug effects | Lipid Peroxidation | Mitochondrial Diseases - physiopathology | Apoptosis | Index Medicus | Topic Highlight
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83. Full Text Mitochondrial DNA disease—molecular insights and potential routes to a cure
by Russell, Oliver and Turnbull, Doug
Experimental cell research, ISSN 0014-4827, 07/2014, Volume 325, Issue 1, pp. 38 - 43
Zinc-finger nucleases | Treatments | TALENs | Mitochondrial disease | Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Mitochondrial Diseases - genetics | Mitochondrial Proton-Translocating ATPases - genetics | Mitochondria - enzymology | Point Mutation | Sequence Deletion | DNA, Mitochondrial - genetics | Mitochondria - genetics | Humans | Mitochondrial Diseases - therapy | RNA, Transfer, Leu - genetics | Genomes | Mitochondrial DNA | Disease | Molecular biology | Pathogenesis | Index Medicus | DISEASES | DNA | GENES | MITOCHONDRIA | SYMPTOMS | MUTATIONS | 60 APPLIED LIFE SCIENCES | ZINC | NUCLEASES | Review
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84. Full Text Upregulated function of mitochondria-associated ER membranes in Alzheimer disease
by Area-Gomez, E and Del Carmen Lara Castillo, M and Tambini, M.D and Guardia-Laguarta, C and Groof, A.J.C. de and Maa, M and Ikenouchi, J and Umeda, M and Bird, T.D and Sturley, S.L and Schon, E.A
The EMBO journal, ISSN 0261-4189, 2012, Volume 31, Issue 21, pp. 4106 - 4123
MAM | APP | cholesterol | phospholipids | presenilin | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | RNA, Small Interfering - genetics | Membrane Microdomains - metabolism | Humans | Endoplasmic Reticulum - metabolism | Presenilin-1 - physiology | Presenilin-2 - physiology | Embryo, Mammalian - metabolism | Alzheimer Disease - pathology | Endoplasmic Reticulum - pathology | Presenilin-1 - antagonists & inhibitors | Real-Time Polymerase Chain Reaction | Fibroblasts - metabolism | Embryo, Mammalian - pathology | Presenilin-2 - antagonists & inhibitors | RNA, Messenger - genetics | Cells, Cultured | Mitochondria - metabolism | Mitochondria - pathology | Fibroblasts - pathology | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Mice, Knockout | Mitochondrial Membranes - metabolism | Animals | Mitochondrial Membranes - pathology | Alzheimer Disease - metabolism | Mice | Subcellular Fractions | Membrane Microdomains - pathology | Proteins | Membranes | Mitochondria | Pathogenesis | Lipids | Alzheimers disease | Gene expression | Molecular biology | Index Medicus
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85. Full Text Human mitochondrial DNA replication machinery and disease
by Young, Matthew J and Copeland, William C
Current opinion in genetics & development, ISSN 0959-437X, 2016, Volume 38, pp. 52 - 62
Medical Education | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Cell Biology | DNA Polymerase gamma | Mitochondrial Diseases - genetics | Mitochondrial Diseases - pathology | Humans | Mitochondrial Proteins - genetics | DNA-Directed DNA Polymerase - genetics | Cell Respiration - genetics | DNA, Mitochondrial - genetics | DNA Replication - genetics | Exodeoxyribonucleases - genetics | Genome, Mitochondrial | Mutation | DNA Helicases - genetics | Ribonuclease H - genetics | DNA polymerases | DNA replication | Genomes | Mitochondrial DNA | Index Medicus | mitochondrial DNA replication | POLG2 | mitochondrial DNA depletion syndrome | ataxia-neuropathy | Alpers syndrome | DNA polymerase γ | progressive external ophthalmoplegia | POLG
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86. Full Text Axonal Charcot–Marie–Tooth disease patient-derived motor neurons demonstrate disease-specific phenotypes including abnormal electrophysiological properties
by Saporta, Mario A and Dang, Vu and Volfson, Dmitri and Zou, Bende and Xie, Xinmin (Simon) and Adebola, Adijat and Liem, Ronald K and Shy, Michael and Dimos, John T
Experimental neurology, ISSN 0014-4886, 01/2015, Volume 263, pp. 190 - 199
Electrophysiology | Motor neurons | Inherited Neuropathies | Axonal Charcot–Marie–Tooth disease | Axonal transport | Induced pluripotent stem cells | Axonal Charcot-Marie-Tooth disease | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Intermediate Filaments - pathology | Cell Separation | Humans | Male | Mitochondrial Proteins - genetics | Mitochondria - pathology | Charcot-Marie-Tooth Disease - pathology | Motor Neurons - pathology | Charcot-Marie-Tooth Disease - genetics | Gene Knock-In Techniques | Neurofilament Proteins - genetics | Point Mutation | Patch-Clamp Techniques | Phenotype | Animals | GTP Phosphohydrolases - genetics | Adult | Female | Mice | Charcot-Marie-Tooth Disease - physiopathology | Electrophysiological Phenomena | Child | Induced Pluripotent Stem Cells | Real-Time Polymerase Chain Reaction | Neurons | Genetic aspects | Index Medicus | Motor Neurons | Axonal Charcot-Marie-Tooth Disease | electrophysiology
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87. Full Text PGC-1α, mitochondrial dysfunction, and Huntington's disease
by Johri, Ashu and Chandra, Abhishek and Flint Beal, M
Free radical biology & medicine, ISSN 0891-5849, 09/2013, Volume 62, pp. 37 - 46
Oxidative stress | Energy metabolism | Mitochondrial dysfunction | Neurodegeneration | Mitochondrial dynamics | Therapeutics | PGC-1α | Huntington's disease | Mitophagy | SIRT1 | PPARs | SIRT3 | Biochemistry & Molecular Biology | Endocrinology & Metabolism | Life Sciences & Biomedicine | Science & Technology | Reactive Oxygen Species - metabolism | Calcium - metabolism | Antioxidants - metabolism | Humans | Huntington Disease - pathology | Mitochondria - metabolism | Mitochondria - pathology | Adenosine Triphosphate - biosynthesis | Huntington Disease - metabolism | Transcription Factors - metabolism | Energy Metabolism | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Trans-Activators - metabolism | Neurons - metabolism | Index Medicus | mitophagy | mitochondrial dysfunction | Huntington’s disease | oxidative stress | energy metabolism | neurodegeneration and therapeutics | mitochondrial dynamics
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