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Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 11/2012, Volume 20, Issue 21, pp. 6384 - 6393
Journal Article
Journal Article
Journal Article
BBA - Bioenergetics, ISSN 0005-2728, 09/2012, Volume 1817, Issue 9, pp. 1537 - 1549
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 06/2014, Volume 289, Issue 23, pp. 15980 - 15985
Purified F-ATP synthase dimers of yeast mitochondria display Ca2+ -dependent channel activity with properties resembling those of the permeability transition... 
COMPLEX I | ORGANIZATION | INHIBITION | DIMER | CRISTAE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PORE | INNER-MEMBRANE | SACCHAROMYCES-CEREVISIAE | HEART-MITOCHONDRIA | CYCLOSPORINE | Mitochondria | Yeast | Calcium | Oxidative Stress | Reports | Ion Channel | F1FO-ATPase | Mitochondrial Permeability Transition (MPT)
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2018, Volume 293, Issue 38, pp. 14632 - 14645
Modification with arginine-specific glyoxals modulates the permeability transition (PT) of rat liver mitochondria, with inhibitory or inducing effects that... 
C-SUBUNIT | calcium | DROSOPHILA-MELANOGASTER | mitochondria | CA2+ RELEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROTEIN GLYCATION | CRISTAE MORPHOLOGY | CHANNEL FORMATION | SACCHAROMYCES-CEREVISIAE | CELL-DEATH | mitochondrial permeability transition (MPT) | ATP synthase | bioenergetics | METHYLGLYOXAL METABOLISM | IN-SITU | Bioenergetics
Journal Article
JOURNAL OF BIOLOGICAL CHEMISTRY, ISSN 0021-9258, 07/2019, Volume 294, Issue 28, pp. 10807 - 10818
The mitochondrial matrix ATPase associated with diverse cellular activities (m-AAA) protease spastic paraplegia 7 (SPG7) has been recently implicated as either... 
calcium | cyclophilin D | spastic paraplegia 7 | protein processing | BIOCHEMISTRY & MOLECULAR BIOLOGY | SENSITIVITY | DEFICIENCY | mitochondrial permeability transition (MPT) | protein turnover | CYCLOSPORINE-A | INHIBITION | CHANNEL | mitochondrial calcium uniporter | F-ATP SYNTHASE | PROTEINS | STRESS
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 02/2016, Volume 291, Issue 9, pp. 4356 - 4373
The mitochondrial permeability transition pore is a recognized drug target for neurodegenerative conditions such as multiple sclerosis and for... 
HUMAN CYCLOPHILIN-D | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | AXONAL DEGENERATION | CYCLOSPORINE-A | TRAUMATIC BRAIN-INJURY | ATP SYNTHASE | TRIPHENYLPHOSPHONIUM CATIONS | BIOCHEMISTRY & MOLECULAR BIOLOGY | EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS | LENTIVIRAL VECTOR | P-GLYCOPROTEIN | Mitochondrial Membrane Transport Proteins - antagonists & inhibitors | Humans | Cerebral Cortex - pathology | Male | Cyclophilins - metabolism | Multiple Sclerosis - prevention & control | Cyclosporins - pharmacology | Mitochondrial Membrane Transport Proteins - genetics | Cyclophilins - antagonists & inhibitors | Neuroprotective Agents - pharmacology | Liver - drug effects | Cyclosporins - therapeutic use | T-Lymphocytes - drug effects | Neurons - metabolism | Cerebral Cortex - drug effects | Neuroprotective Agents - adverse effects | Quinolinium Compounds - therapeutic use | Quinolinium Compounds - adverse effects | Cyclosporins - chemical synthesis | Mitochondrial Membrane Transport Proteins - metabolism | Liver - metabolism | Recombinant Proteins - chemistry | Cyclophilins - genetics | Random Allocation | Mice, Knockout | Cerebral Cortex - immunology | Peptides, Cyclic - therapeutic use | Mutation | Peptides, Cyclic - adverse effects | Neuroprotective Agents - therapeutic use | Neurons - pathology | Peptides, Cyclic - pharmacology | Cerebral Cortex - metabolism | Quinolinium Compounds - pharmacology | T-Lymphocytes - pathology | Neurons - drug effects | Multiple Sclerosis - metabolism | Recombinant Proteins - metabolism | Cells, Cultured | Cyclosporins - adverse effects | Neurons - immunology | Mice, Inbred Strains | Hep G2 Cells | Animals | Peptides, Cyclic - chemical synthesis | Quinolinium Compounds - chemical synthesis | Multiple Sclerosis - immunology | Multiple Sclerosis - pathology | Cell Proliferation - drug effects | Amino Acid Substitution | Index Medicus | X-ray crystallography | Molecular Bases of Disease | mitochondrial permeability transition (MPT) | cyclophilin D | neurodegenerative disease | multiple sclerosis | neurodegeneration | EAE | cyclosporin | mitochondrial targeting
Journal Article
JOURNAL OF BIOLOGICAL CHEMISTRY, ISSN 0021-9258, 07/2019, Volume 294, Issue 28, pp. 10987 - 10997
Journal Article