X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (74608) 74608
Dissertation (180) 180
Book Chapter (163) 163
Newsletter (68) 68
Publication (46) 46
Conference Proceeding (23) 23
Government Document (21) 21
Reference (20) 20
Web Resource (17) 17
Book / eBook (11) 11
Magazine Article (4) 4
Streaming Video (4) 4
Book Review (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
science & technology (59472) 59472
life sciences & biomedicine (56224) 56224
animals (43928) 43928
humans (38869) 38869
mitogen-activated protein kinases - metabolism (22053) 22053
mice (20636) 20636
phosphorylation (19374) 19374
signal transduction (17671) 17671
biochemistry & molecular biology (17153) 17153
cell biology (14884) 14884
rats (14186) 14186
male (14084) 14084
cells, cultured (13996) 13996
p38 mitogen-activated protein kinases - metabolism (13498) 13498
mitogen-activated protein kinase 1 - metabolism (11200) 11200
cell line (10308) 10308
apoptosis (10031) 10031
female (9690) 9690
signal transduction - drug effects (9405) 9405
enzyme activation (9086) 9086
cell line, tumor (8765) 8765
mitogen-activated protein kinase 3 - metabolism (8584) 8584
enzyme inhibitors - pharmacology (8381) 8381
oncology (7926) 7926
jnk mitogen-activated protein kinases - metabolism (7202) 7202
apoptosis - drug effects (7047) 7047
kinases (6925) 6925
proteins (6852) 6852
blotting, western (6737) 6737
phosphorylation - drug effects (6521) 6521
nf-kappa b - metabolism (5979) 5979
pharmacology & pharmacy (5912) 5912
protein kinases (5690) 5690
enzyme activation - drug effects (5548) 5548
mitogen-activated protein kinases (5488) 5488
signal transduction - physiology (5463) 5463
rats, sprague-dawley (5403) 5403
gene expression (5391) 5391
research (5133) 5133
dose-response relationship, drug (5051) 5051
map kinase signaling system - drug effects (5019) 5019
p38 mitogen-activated protein kinases (4939) 4939
mitogen-activated protein kinase (4927) 4927
immunology (4915) 4915
neurosciences (4787) 4787
time factors (4758) 4758
map kinase (4711) 4711
transfection (4692) 4692
neurosciences & neurology (4679) 4679
mitogen-activated protein kinase kinases - metabolism (4662) 4662
map kinase signaling system (4418) 4418
mitogen-activated protein kinases - antagonists & inhibitors (4265) 4265
analysis (4239) 4239
mice, inbred c57bl (4179) 4179
rna, messenger - metabolism (4119) 4119
jnk mitogen-activated protein kinases (4115) 4115
mitogen-activated protein kinase 3 (4113) 4113
cell proliferation - drug effects (4104) 4104
cell proliferation (4045) 4045
inflammation (3980) 3980
phosphatidylinositol 3-kinases - metabolism (3947) 3947
physiological aspects (3939) 3939
abridged index medicus (3926) 3926
proto-oncogene proteins c-akt - metabolism (3889) 3889
protein-serine-threonine kinases - metabolism (3885) 3885
research article (3885) 3885
extracellular signal-regulated map kinases - metabolism (3820) 3820
reactive oxygen species - metabolism (3707) 3707
imidazoles - pharmacology (3653) 3653
physiology (3649) 3649
pyridines - pharmacology (3648) 3648
flavonoids - pharmacology (3542) 3542
cell survival - drug effects (3528) 3528
p38 mitogen-activated protein kinases - antagonists & inhibitors (3515) 3515
protein kinase inhibitors - pharmacology (3355) 3355
map kinase signaling system - physiology (3290) 3290
mutation (3260) 3260
disease models, animal (3245) 3245
cancer (3187) 3187
tumor cells, cultured (3177) 3177
molecular sequence data (3171) 3171
calcium-calmodulin-dependent protein kinases - metabolism (3163) 3163
protein binding (3151) 3151
mitogen-activated protein kinases - genetics (3122) 3122
science & technology - other topics (3117) 3117
gene expression regulation (3078) 3078
multidisciplinary sciences (3057) 3057
reverse transcriptase polymerase chain reaction (3052) 3052
extracellular signal-regulated kinase (3019) 3019
mapk (3011) 3011
mitogens (2989) 2989
mice, knockout (2976) 2976
oxidative stress (2968) 2968
medicine, research & experimental (2940) 2940
research & experimental medicine (2935) 2935
biophysics (2856) 2856
endocrinology & metabolism (2836) 2836
amino acid sequence (2813) 2813
rna, messenger - genetics (2781) 2781
health aspects (2736) 2736
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (74510) 74510
Chinese (978) 978
Japanese (705) 705
Korean (93) 93
Russian (67) 67
French (48) 48
Portuguese (42) 42
German (28) 28
Spanish (23) 23
Polish (16) 16
Hungarian (12) 12
Czech (7) 7
Dutch (7) 7
Norwegian (6) 6
Turkish (5) 5
Ukrainian (5) 5
Italian (3) 3
Swedish (3) 3
Danish (2) 2
Romanian (2) 2
Croatian (1) 1
Hebrew (1) 1
Slovak (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Biochemical journal, ISSN 1470-8728, 12/2007, Volume 408, Issue 3, pp. 297 - 315
The specificities of 65 compounds reported to be relatively specific inhibitors of protein kinases have been profiled against a panel of 70-80 protein kinases... 
Drug discovery | Kinase profiling | Protein kinase | Anti-cancer drugs | Inhibitor specificity | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Amino Acid Sequence | Cell Line | Phosphorylation | Recombinant Proteins - antagonists & inhibitors | Animals | Mitogen-Activated Protein Kinases - antagonists & inhibitors | Humans | Drug Design | Protein Kinase Inhibitors - pharmacology | Enzyme Activation | Mitogen-Activated Protein Kinases - metabolism | Spodoptera | Index Medicus | Yes1, Yamaguchi sarcoma viral oncogene homologue 1 | CSK, C-terminal Src kinase | Lck, lymphocyte cell-specific protein-tyrosine kinase | EGF, epidermal growth factor | FGF-R, fibroblast-growth-factor receptor | PAK, p21-activated protein kinase | PDK, 3-phosphoinositide-dependent protein kinase | PI3K, phosphatidylinositol (phosphoinositide) 3-kinase | NEK, NIMA (never in mitosis in Aspergillus nidulans)-related kinase | RSK, p90 ribosomal S6 kinase | HEK-293 cells, human embryonic kidney-293 cells | VEGF, vascular endothelial growth factor (vasoendothelial growth factor) | EF2K, elongation-factor-2 kinase | CK, casein kinase | PTEN, phosphatase and tensin homologue deleted on chromosome 10 | ERK, extracellular-signal-regulated kinase | ATM, ataxia telangiectasia mutated | drug discovery | SRPK, serine-arginine protein kinase | IL-1, interleukin 1 | MNK, MAPK-integrating protein kinase | ROCK, Rho-dependent protein kinase | CaMKK, CaMK kinase | GST, glutathione transferase | MKK1, MAPK kinase-1 (also called MEK1, MAPK or ERK kinase 1) | GAK, cyclin G-associated kinase | inhibitor specificity | FMK, fluoromethylketone | MST, mammalian homologue Ste20-like kinase | PKA, cAMP-dependent protein kinase | FKBP, FK506-binding protein | PPAR, peroxisome-proliferator-activated receptor | IKK, inhibitory κB kinase | PH, pleckstrin homology | MBP, myelin basic protein | AICAR, aminoimidazole-4-carboxamide-1-β-D-ribofuranoside | MAPKAP-K, MAPK-activated protein kinase | Sf21, Spodoptera frugiperda (fall armyworm) 21 | MARK, microtubule-affinity-regulating kinase | PIM, provirus integration site for Moloney murine leukaemia virus | LPS, lipopolysaccharide | MSK, mitogen- and stress-activated protein kinase | anti-cancer drugs | MAPK, mitogen-activated protein kinase | MELK, maternal embryonic leucine-zipper kinase | His6, hexahistidine | CAK, cyclin-dependent kinase-activating kinase | Eph-A2, Ephrin A2 receptor | PLK, polo-like kinase | ATF2, activating transcription factor 2 | PKD, protein kinase D | Src, sarcoma kinase | AMPK, AMP-activated protein kinase | MMS, methyl methanesulfonate | CHK, checkpoint kinase | JNK, c-Jun N-terminal kinase | TORC1, mTOR (mammalian target of rapamycin)–raptor (regulatory associated protein of mTOR) complex | protein kinase | BRSK, brain-specific kinase | RIP2, receptor-interacting protein 2 | kinase profiling | IGF-1, insulin-like growth factor-1 | S6K1, S6 kinase 1 | DYRK, dual-specificity tyrosine-phosphorylated and -regulated kinase | HIPK, homeodomain-interacting protein kinase | ZMP, aminoimidazole-4-carboxamide-1-β-D-ribofuranoside monophosphate | PRAK, p38-regulated activated kinase | PKC, protein kinase C | Src-I1, Src inhibitor 1 | TANK, TRAF (tumour-necrosis-factor-receptor-associated factor)-family-member-associated nuclear factor κB activator | NFAT, nuclear factor for activated T-cells | PHK, phosphorylase kinase | GSK3, glycogen synthase kinase 3 | PKB, protein kinase B (also called Akt) | CaMK, calmodulin-dependent kinase | CDK, cyclin-dependent protein kinase | NDRG, N-myc downstream-regulated gene | SmMLCK, smooth-muscle myosin light-chain kinase | TBK1, TANK-binding kinase 1 | PRK, protein kinase C-related kinase | SGK, serum- and glucocorticoid-induced kinase
Journal Article
Apoptosis (London), ISSN 1360-8185, 3/2008, Volume 13, Issue 3, pp. 343 - 353
Journal Article
Cancer research (Chicago, Ill.), ISSN 1538-7445, 09/2017, Volume 77, Issue 17, pp. 4602 - 4612
Identifying critical factors involved in the metastatic progression of hepatocellular carcinoma (HCC) may offer important therapeutic opportunities. Here, we... 
Life Sciences & Biomedicine | Oncology | Science & Technology | Prognosis | Humans | Lung Neoplasms - metabolism | Tumor Protein p73 - genetics | Gene Expression Profiling | Tumor Protein p73 - metabolism | Heat-Shock Proteins - genetics | Neoplasm Metastasis | Lung Neoplasms - secondary | Carcinoma, Hepatocellular - genetics | Mitogen-Activated Protein Kinase 1 - genetics | Dual-Specificity Phosphatases - genetics | Liver Neoplasms - pathology | Tumor Cells, Cultured | Lung Neoplasms - genetics | Liver Neoplasms - genetics | Mitogen-Activated Protein Kinase 3 - genetics | Signal Transduction | Dual-Specificity Phosphatases - metabolism | Heat-Shock Proteins - metabolism | Mitogen-Activated Protein Kinase Phosphatases - genetics | Xenograft Model Antitumor Assays | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Mitogen-Activated Protein Kinase 3 - metabolism | Mice, Nude | Carcinoma, Hepatocellular - pathology | Liver Neoplasms - metabolism | Protein Array Analysis | Mice | Mice, Inbred BALB C | Carcinoma, Hepatocellular - metabolism | Mitogen-Activated Protein Kinase 1 - metabolism | Mitogen-Activated Protein Kinase Phosphatases - metabolism | Liver | Extracellular signal-regulated kinase | Hepatocellular carcinoma | Metastasis | Metastases | Liver cancer | Signal transduction | Signaling | Stress response | Binding sites | Cellular stress response | Tumors | Apoptosis | Cancer | Index Medicus | Liver Neoplasms | Lung Neoplasms | Life Sciences | Tumor Protein p73 | Heat-Shock Proteins | Mitogen-Activated Protein Kinase Phosphatases | Carcinoma, Hepatocellular | Dual-Specificity Phosphatases | Mitogen-Activated Protein Kinase 1 | Mitogen-Activated Protein Kinase 3 | Carrier Proteins
Journal Article
Journal Article
Biochemical journal, ISSN 0264-6021, 07/2009, Volume 421, Issue 1, pp. 29 - 42
... (protein kinase A/protein kinase G/protein kinase Q family kinases such as Akt (protein kinase 13), S6K (p70 ribosomal S6 kinase... 
Phosphoinositide 3-kinase (PI3K) | Akt/protein kinase B (PKB) | Serum and glucocorticoid protein kinase (SGK) | P70 ribosomal S6 kinase (S6K) | Kinase inhibitor | Cancer | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Cell Line | Humans | Multiprotein Complexes | Morpholines - pharmacology | Transcription Factors - antagonists & inhibitors | Gene Expression Profiling | G1 Phase - drug effects | Pyrimidines - pharmacology | Morpholines - chemistry | Pyrimidines - chemistry | Mechanistic Target of Rapamycin Complex 1 | Gene Expression Regulation - drug effects | Proteins | Transcription Factors - metabolism | Animals | Fibroblasts - drug effects | Cell Proliferation - drug effects | Mice | TOR Serine-Threonine Kinases | Fibroblasts - metabolism | Index Medicus | PI3K, phosphoinositide 3-kinase | PDK, 3-phosphoinositide-dependent protein kinase | AMPK, AMP-activated protein kinase | mTORC, mTOR complex | DTT, dithiothreitol | phosphoinositide 3-kinase (PI3K) | p70 ribosomal S6 kinase (S6K) | SPHK, sphingosine kinase | ERK, extracellular-signal-regulated kinase | RSK, ribosomal S6 kinase | PH domain, pleckstrin homology domain | protein kinase B (PKB) | protein kinase G | NDRG1, N-Myc downstream-regulated gene-1 | IGF, insulin-like growth factor | mTOR, mammalian target of rapamycin | GST, glutathione transferase | SGK, serum and glucocorticoid protein kinase | PKC, protein kinase C | S6K, p70 ribosomal S6 kinase | eIF4E, eukaryotic initiation factor 4E | 4E-BP1, eIF4E-binding protein 1 | protein kinase C family | Akt | PRAS40, proline-rich Akt substrate of 40 kDa | HEK-293 cell, human embryonic kidney 293 cell | kinase inhibitor | MEF, mouse embryonic fibroblast | AGC family, protein kinase A | cancer | serum and glucocorticoid protein kinase (SGK) | MAPK, mitogen-activated protein kinase
Journal Article