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Biochemical journal, ISSN 1470-8728, 2007, Volume 408, Issue 3, pp. 297 - 315
The specificities of 65 compounds reported to be relatively specific inhibitors of protein kinases have been profiled against a panel of 70-80 protein kinases... 
Drug discovery | Kinase profiling | Protein kinase | Anti-cancer drugs | Inhibitor specificity | RHO-ASSOCIATED KINASE | TUMOR PROGRESSION | FAMILY-MEMBERS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL-PROLIFERATION | protein kinase | P38 MAP KINASE | CYCLIN-DEPENDENT KINASES | RECEPTOR TYROSINE KINASES | drug discovery | kinase profiling | SB 203580 | anti-cancer drugs | ISOFORMS IN-VITRO | P90 RSK | inhibitor specificity | Amino Acid Sequence | Cell Line | Phosphorylation | Recombinant Proteins - antagonists & inhibitors | Animals | Mitogen-Activated Protein Kinases - antagonists & inhibitors | Humans | Drug Design | Protein Kinase Inhibitors - pharmacology | Enzyme Activation | Mitogen-Activated Protein Kinases - metabolism | Spodoptera | Yes1, Yamaguchi sarcoma viral oncogene homologue 1 | CSK, C-terminal Src kinase | Lck, lymphocyte cell-specific protein-tyrosine kinase | EGF, epidermal growth factor | FGF-R, fibroblast-growth-factor receptor | PAK, p21-activated protein kinase | PDK, 3-phosphoinositide-dependent protein kinase | PI3K, phosphatidylinositol (phosphoinositide) 3-kinase | NEK, NIMA (never in mitosis in Aspergillus nidulans)-related kinase | RSK, p90 ribosomal S6 kinase | HEK-293 cells, human embryonic kidney-293 cells | VEGF, vascular endothelial growth factor (vasoendothelial growth factor) | EF2K, elongation-factor-2 kinase | CK, casein kinase | PTEN, phosphatase and tensin homologue deleted on chromosome 10 | ERK, extracellular-signal-regulated kinase | ATM, ataxia telangiectasia mutated | SRPK, serine-arginine protein kinase | IL-1, interleukin 1 | MNK, MAPK-integrating protein kinase | ROCK, Rho-dependent protein kinase | CaMKK, CaMK kinase | GST, glutathione transferase | MKK1, MAPK kinase-1 (also called MEK1, MAPK or ERK kinase 1) | GAK, cyclin G-associated kinase | FMK, fluoromethylketone | MST, mammalian homologue Ste20-like kinase | PKA, cAMP-dependent protein kinase | FKBP, FK506-binding protein | PPAR, peroxisome-proliferator-activated receptor | IKK, inhibitory κB kinase | PH, pleckstrin homology | MBP, myelin basic protein | AICAR, aminoimidazole-4-carboxamide-1-β-D-ribofuranoside | MAPKAP-K, MAPK-activated protein kinase | Sf21, Spodoptera frugiperda (fall armyworm) 21 | MARK, microtubule-affinity-regulating kinase | PIM, provirus integration site for Moloney murine leukaemia virus | LPS, lipopolysaccharide | MSK, mitogen- and stress-activated protein kinase | MAPK, mitogen-activated protein kinase | MELK, maternal embryonic leucine-zipper kinase | His6, hexahistidine | CAK, cyclin-dependent kinase-activating kinase | Eph-A2, Ephrin A2 receptor | PLK, polo-like kinase | ATF2, activating transcription factor 2 | PKD, protein kinase D | Src, sarcoma kinase | AMPK, AMP-activated protein kinase | MMS, methyl methanesulfonate | CHK, checkpoint kinase | JNK, c-Jun N-terminal kinase | TORC1, mTOR (mammalian target of rapamycin)–raptor (regulatory associated protein of mTOR) complex | BRSK, brain-specific kinase | RIP2, receptor-interacting protein 2 | IGF-1, insulin-like growth factor-1 | S6K1, S6 kinase 1 | DYRK, dual-specificity tyrosine-phosphorylated and -regulated kinase | HIPK, homeodomain-interacting protein kinase | ZMP, aminoimidazole-4-carboxamide-1-β-D-ribofuranoside monophosphate | PRAK, p38-regulated activated kinase | PKC, protein kinase C | Src-I1, Src inhibitor 1 | TANK, TRAF (tumour-necrosis-factor-receptor-associated factor)-family-member-associated nuclear factor κB activator | NFAT, nuclear factor for activated T-cells | PHK, phosphorylase kinase | GSK3, glycogen synthase kinase 3 | PKB, protein kinase B (also called Akt) | CaMK, calmodulin-dependent kinase | CDK, cyclin-dependent protein kinase | NDRG, N-myc downstream-regulated gene | SmMLCK, smooth-muscle myosin light-chain kinase | TBK1, TANK-binding kinase 1 | PRK, protein kinase C-related kinase | SGK, serum- and glucocorticoid-induced kinase
Journal Article
PLoS genetics, ISSN 1553-7404, 2012, Volume 8, Issue 7, p. e1002816
.... It lacks the membrane docking yeast Ste5 scaffold homolog; but, similar to yeast, the entire MAPK module's proteins interact with each other at the plasma membrane... 
YEAST | ACTIVATED PROTEIN-KINASE | PHEROMONE RESPONSE PATHWAY | GENETICS & HEREDITY | BIMOLECULAR FLUORESCENCE COMPLEMENTATION | SACCHAROMYCES-CEREVISIAE | PLASMA-MEMBRANE | ADAPTER PROTEIN | SEXUAL DEVELOPMENT | NEUROSPORA-CRASSA | LIVING CELLS | Protein Kinases - metabolism | MAP Kinase Signaling System - physiology | Mitogen-Activated Protein Kinase Kinases - genetics | Protein Kinases - genetics | Sexual Development - genetics | Signal Transduction | MAP Kinase Kinase Kinases - genetics | MAP Kinase Kinase Kinases - metabolism | Pheromones - metabolism | Saccharomyces cerevisiae Proteins - genetics | Aspergillus nidulans - metabolism | Saccharomyces cerevisiae - metabolism | Mitogen-Activated Protein Kinase Kinases - metabolism | Nuclear Envelope - metabolism | Cell Nucleus - metabolism | MAP Kinase Signaling System - genetics | Saccharomyces cerevisiae Proteins - metabolism | Mitogen-Activated Protein Kinases - genetics | Cell Membrane - metabolism | Aspergillus nidulans - growth & development | Saccharomyces cerevisiae - growth & development | Mitogen-Activated Protein Kinases - metabolism | Pheromones - genetics | Aspergillus | Microbial genetics | Physiological aspects | Genetic aspects | Research | Metabolism | Health aspects | Mitogen-activated protein kinases | Proteins | Fungi | Enzymes | Pheromones | Kinases
Journal Article
Nature cell biology, ISSN 1476-4679, 2007, Volume 9, Issue 3, pp. 324 - 330
The mitogen-activated protein kinase (MAPK) network is a conserved signalling module that regulates cell fate by transducing a myriad of growth-factor signals... 
ACTIVATION | PROTEIN | SPECIFICITY | PHOSPHORYLATION | DYNAMICS | RAF-1 | CASCADE | IDENTIFICATION | SIGNAL-REGULATED KINASE | TRANSIENT | CELL BIOLOGY | RNA, Small Interfering - genetics | MAP Kinase Signaling System - physiology | Tetradecanoylphorbol Acetate - pharmacology | Receptor, trkA - antagonists & inhibitors | Extracellular Signal-Regulated MAP Kinases - metabolism | PC12 Cells | MAP Kinase Kinase 1 - genetics | Flow Cytometry | Mitogen-Activated Protein Kinase 1 - genetics | Phosphorylation - drug effects | Cell Differentiation - physiology | Proto-Oncogene Proteins B-raf - metabolism | Mitogen-Activated Protein Kinase 3 - genetics | Proto-Oncogene Proteins c-raf - genetics | Nerve Growth Factor - pharmacology | Rats | MAP Kinase Kinase 1 - metabolism | Protein Kinase C - antagonists & inhibitors | Proto-Oncogene Proteins c-raf - metabolism | Animals | MAP Kinase Signaling System - drug effects | Mitogen-Activated Protein Kinase 3 - metabolism | Cell Differentiation - drug effects | Intercellular Signaling Peptides and Proteins - pharmacology | Models, Biological | Proto-Oncogene Proteins B-raf - genetics | Cell Proliferation - drug effects | Protein Kinase Inhibitors - pharmacology | Epidermal Growth Factor - pharmacology | Cell Cycle - drug effects | Monte Carlo Method | Mitogen-Activated Protein Kinase 1 - metabolism | Cell proliferation | Evaluation | Pheochromocytoma | Physiological aspects | Cell differentiation | Properties | Protein kinases | Growth factors
Journal Article
PloS one, ISSN 1932-6203, 2014, Volume 9, Issue 6, p. e100893
.... BANCR knockdown induced by shRNA transfection significantly inhibited proliferation of tumor cells and inactivated MAPK pathway... 
CELLS | EPIDERMAL NEOPLASIA | METASTASIS | MULTIDISCIPLINARY SCIENCES | KINASE | DISEASE | GROWTH | TUMOR | INHIBITOR U0126 | MECHANISMS | CANCER | Cell Proliferation | Prognosis | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Male | Gene Knockdown Techniques | MAP Kinase Signaling System | Heterografts | MAP Kinase Kinase 4 - metabolism | Melanoma - genetics | Mitogen-Activated Protein Kinase 1 - genetics | Adult | Female | p38 Mitogen-Activated Protein Kinases - metabolism | Disease Models, Animal | Melanoma - metabolism | Mitogen-Activated Protein Kinase 3 - genetics | Proto-Oncogene Proteins c-raf - genetics | p38 Mitogen-Activated Protein Kinases - genetics | RNA, Long Noncoding - genetics | Melanoma - pathology | Proto-Oncogene Proteins c-raf - metabolism | Animals | Mitogen-Activated Protein Kinase 3 - metabolism | Cell Line, Tumor | MAP Kinase Kinase 4 - genetics | Aged | Mice | Neoplasm Staging | Melanoma - mortality | Mitogen-Activated Protein Kinase 1 - metabolism | RNA | Melanoma | Cell proliferation | Disease | Pathogenesis | Metastasis | Kinases | Cancer therapies | Skin cancer | Proteins | Ethics | Cell growth | Transfection | Animal tissues | Tumorigenesis | Trends | Inhibition | Dermatology | Tumor cells | Extracellular signal-regulated kinase | MAP kinase | JNK protein | Tumorigenicity | Gene expression | Ribonucleic acid--RNA | Patients | Pathology | Hospitals | Non-coding RNA | Cancer | Ribonucleic acid
Journal Article
American journal of physiology: endocrinology and metabolism, ISSN 0193-1849, 01/2011, Volume 300, Issue 1, pp. E103 - E110
Journal Article
Nature (London), ISSN 1476-4687, 2012, Volume 482, Issue 7385, pp. 419 - 422
Journal Article
The Journal of biological chemistry, ISSN 1083-351X, 2009, Volume 284, Issue 19, pp. 13165 - 13173
Journal Article