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Molecular & Cellular Oncology, ISSN 2372-3556, 05/2019, Volume 6, Issue 3, pp. 1600350 - 1600350
In our recent publication, we describe a mechanism by which peroxisomes are protected from degradation by autophagy under basal conditions. Taking a page from... 
pexophagy | Mitophagy
Journal Article
MOVEMENT DISORDERS, ISSN 0885-3185, 09/2016, Volume 31, Issue 9, pp. 1340 - 1340
Journal Article
Genes and Development, ISSN 0890-9369, 2015, Volume 29, Issue 10, pp. 989 - 999
In this review, Durcan and Fon discuss how post-translational modifications are at the heart of how PARKIN and PINK1 function in mitochondrial quality control.... 
Ubiquitin | PARKIN | Phosphorylation | PINK1 | Mitophagy | Deubiquitination | mitophagy | deubiquitination | Review | phosphorylation | ubiquitin
Journal Article
Autophagy, ISSN 1554-8627, 11/2019, Volume 15, Issue 11, pp. 2002 - 2011
Mitochondrial quality control is essential for maintaining a healthy population of mitochondria. Two proteins associated with Parkinson disease, the kinase... 
PRKN | BSA | CCCP | mitophagy | PINK1
Journal Article
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, ISSN 1388-1981, 04/2014, Volume 1841, Issue 4, pp. 525 - 534
Normal cellular function is dependent on a number of highly regulated homeostatic mechanisms, which act in concert to maintain conditions suitable for life.... 
GCN5L1 | Sirt3 | Acetylation | Mitophagy | Autophagy
Journal Article
Autophagy, ISSN 1554-8627, 2019, pp. 1 - 16
Mitophagy, which is a conserved cellular process for selectively removing damaged or unwanted mitochondria, is critical for mitochondrial quality control and... 
PGAM5 | PINK1-PRKN | Mitophagy | PHB2 | PARL
Journal Article
Autophagy, ISSN 1554-8627, 2019, pp. 1 - 19
Mitochondrial dynamics is highly implicated in a plethora of cellular processes including apoptosis and mitophagy. However, little is known about the scope and... 
BAX | mitophagy | MIEF1 | mitochondria | Apoptosis
Journal Article
Biological and Pharmaceutical Bulletin, ISSN 0918-6158, 2019, Volume 42, Issue 3, pp. 401 - 410
Ridaifen (RID)-B is an analog derived from tamoxifen (TAM). TAM has an antitumor effect by acting as an antagonist to estrogen receptor (ER). However, TAM is... 
Journal Article
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, ISSN 0892-6638, 09/2019, Volume 33, Issue 9, pp. 9742 - 9751
Mitophagy has been implicated in mitochondrial quality control and in various human diseases. However, the study of mitophagy remains limited. We previously... 
PROTEIN | in vivo mitophagy | BIOCHEMISTRY & MOLECULAR BIOLOGY | quantitation of mitophagy | NEURODEGENERATION | PINK1/PARKIN MITOPHAGY | CELL BIOLOGY | FLY | PINK1 | Drosophila model | DISEASES | GENE | confocal microscopy | BIOLOGY | MITOCHONDRIAL DYSFUNCTION | MELANOGASTER | PROGRAMMED AUTOPHAGY | Index Medicus
Journal Article
Toxicology in Vitro, ISSN 0887-2333, 08/2018, Volume 50, pp. 217 - 224
Hematotoxicity of benzene is derived mainly from its active metabolite, 1,4-Benzoquinone (1,4-BQ), which induces cell apoptosis and mitochondrial damage.... 
Benzene | Mitophagy | Autophagy | 1,4-Benzoquinone | Apoptosis
Journal Article
Annals of the New York Academy of Sciences, ISSN 0077-8923, 2019
Increased oxidative stress in patients with type 2 diabetes mellitus (T2DM) results in abnormalities in cell repair processes, such as mitophagy, which... 
T2DM | AMPK | metformin | mitophagy | PBMCs | Index Medicus
Journal Article
BBA - Molecular Basis of Disease, ISSN 0925-4439, 07/2019, Volume 1865, Issue 7, pp. 1905 - 1914
Mitochondrial dysfunction contributes to heart failure induced mortality in approximately 80% of diabetic patients. Mitophagy degrades defective mitochondria... 
Sirt3 | Diabetic cardiomyopathy | Mitophagy | Mst1 | Parkin
Journal Article
Autophagy, ISSN 1554-8627, 06/2019, Volume 15, Issue 6, pp. 1112 - 1114
Our latest publication on the inhibition of Alzheimer disease (AD) through mitophagy consolidates the 'defective mitophagy hypothesis of AD etiology'. Dementia... 
memory | mitochondria | aging | Mitophagy | Alzheimer's disease
Journal Article
International journal of cardiology, ISSN 0167-5273, 07/2019
The therapeutic potential of doxorubicin (DOX) is limited by cardiotoxicity. Rubicon is an inhibitory interacting partner of autophagy protein UVRAG.... 
Journal Article
Journal of Cell Science, ISSN 0021-9533, 2014, Volume 127, Issue 15, pp. 3280 - 3293
Depolarized mitochondria are degraded by mitophagy in a process that depends on the Parkinson's disease gene products PINK1 and Parkin. This is accompanied by... 
Ubiquitin | Mitophagy | UBE2 | Parkin | Proteasome | P62/SQSTM1 | PROTEIN LIGASE | AUTOPHAGY | CELL BIOLOGY | PINK1/PARKIN-MEDIATED MITOPHAGY | MITOCHONDRIAL DEPOLARIZATION | DISEASE | DEGRADATION | MUTATIONS | CHAINS | Index Medicus
Journal Article
ACS Applied Materials and Interfaces, ISSN 1944-8244, 04/2017, Volume 9, Issue 15, pp. 13304 - 13314
Phosphorescent Ir(III) complexes are expected to be new multifunctional theranostic platforms that enable the integration of imaging capabilities and... 
phosphorescent emission | mitophagy | iridium(III) complex | theranostic | mitochondria | PHOTODYNAMIC ANTICANCER | MATERIALS SCIENCE, MULTIDISCIPLINARY | NANOSCIENCE & NANOTECHNOLOGY | MECHANISMS | DEATH | DEGRADATION | AGENTS | STRESS | AUTOPHAGY MITOPHAGY | PROBE | DERIVATIVES
Journal Article
BioScience Trends, ISSN 1881-7815, 2018
Mitochondrial damage is involved in the pathogenesis of osteoarthritis. Metformin, one of the most common prescriptions for patients with type 2 diabetes, can... 
mitophagy | Osteoarthritis | SIRT3
Journal Article
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