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Journal of Proteome Research, ISSN 1535-3893, 01/2017, Volume 16, Issue 1, pp. 156 - 169
The human acute monocytic leukemia cell line THP-1 is widely used as an in vitro phagocytic cell model because it exhibits several immune properties similar to... 
monocyte-to-macrophage differentiation | glycosyltransferases | glycosylation | mass spectrometry | glycosphingolipids | DENDRITIC CELLS | BIOCHEMICAL RESEARCH METHODS | HL-60 CELLS | N-GLYCOSYLATION | IN-VITRO | E-SELECTIN | LEUKEMIA-CELLS | SIALIDASE ACTIVITY | MYELOID FIBRONECTIN RECEPTORS | PROTEIN GLYCOSYLATION | EXPRESSION | Macrophages - chemistry | Mannose - immunology | Monocytes - cytology | Humans | N-Acetylglucosaminyltransferases - genetics | Neuraminidase - genetics | Sialyltransferases - immunology | G(M3) Ganglioside - chemistry | Monocytes - immunology | Glycosphingolipids - immunology | Sialic Acids - chemistry | Neuraminidase - immunology | Polysaccharides - chemistry | Glycosyltransferases - genetics | Fucosyltransferases - immunology | Sialic Acids - immunology | Macrophages - immunology | Mannose - chemistry | Carbohydrate Sequence | Cell Line | Fucosyltransferases - genetics | Glycosyltransferases - immunology | N-Acetylglucosaminyltransferases - immunology | Gene Expression Regulation | Sialyltransferases - genetics | Glycosylation | Polysaccharides - immunology | Macrophages - cytology | Monocytes - chemistry | Cell Differentiation - immunology | G(M3) Ganglioside - immunology | Carbohydrate Conformation | Glycosphingolipids - chemistry | Life Sciences | Populations and Evolution | Biotechnology | Quantitative Methods | Biochemistry, Molecular Biology | Genomics | Biomolecules | Molecular biology | Molecular Networks | Biodiversity | Systematics, Phylogenetics and taxonomy | Cancer
Journal Article
Biological and Pharmaceutical Bulletin, ISSN 0918-6158, 2018, Volume 41, Issue 8, pp. 1228 - 1236
The objective of this study was to investigate the effect of dibenzoylmethane (DBM) on monocyte-to-macrophage differentiation, the inflammatory response, and... 
Journal Article
Journal Article
Oncotarget, ISSN 1949-2553, 03/2018, Volume 9, Issue 19, p. 14959
The liver is a vital target for sepsis-related injury, leading to inflammatory pathogenesis, multiple organ dysfunction and high mortality rates.... 
Journal Article
Molecular Biology Reports, ISSN 0301-4851, 5/2012, Volume 39, Issue 5, pp. 5643 - 5650
Macrophage activation is modulated by both environmental cues and endogenous programs. In the present study, we investigated the role of a PAQR family protein,... 
Life Sciences | Animal Biochemistry | PAQR family | Monocyte to macrophage differentiation-associated (MMD) | Akt | Macrophages | Animal Anatomy / Morphology / Histology | Erk | Monocyte to macrophage differentiationassociated (MMD) | RAS | BIOCHEMISTRY & MOLECULAR BIOLOGY | PAQR family Erk | NOTCH | RECEPTOR | RKTG | MICROGLIAL CELLS | GROWTH | NF-KAPPA-B | UP-REGULATION | EXPRESSION | POLARIZATION | Receptors, Notch - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Cell Differentiation - genetics | Lymphokines - genetics | Lymphokines - metabolism | Membrane Proteins - metabolism | Phosphorylation - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Cell Line | Immunoglobulin J Recombination Signal Sequence-Binding Protein - metabolism | Nitric Oxide - biosynthesis | Intracellular Space - drug effects | Up-Regulation - genetics | Macrophages - cytology | Enzyme Activation - drug effects | Macrophages - enzymology | Up-Regulation - drug effects | Animals | Signal Transduction - drug effects | Cell Differentiation - drug effects | Intracellular Space - metabolism | Lipopolysaccharides - pharmacology | Macrophages - drug effects | Mice | Tumor Necrosis Factor-alpha - biosynthesis | Phosphorylation | Transcription factors | Extracellular signal-regulated kinase | Lysosomes | AKT protein | Golgi apparatus | Lipopolysaccharides | Cell activation | Mitochondria | Monocytes | Molecular modelling | Nitric oxide | Notch protein | Differentiation | Fusion protein | Endoplasmic reticulum | Cytoplasm | Tumor necrosis factor- alpha
Journal Article
中国医学科学杂志:英文版, ISSN 1001-9294, 2013, Volume 28, Issue 2, pp. 82 - 87
Journal Article
DEVELOPMENT, ISSN 0950-1991, 07/2019, Volume 146, Issue 14, p. dev176180
The discovery of a fetal origin for tissue-resident macrophages (trMacs) has inspired an intense search for the mechanisms underlying their development. Here,... 
PROGENITORS | DEVELOPMENTAL BIOLOGY | Developmental hematopoiesis | MYELOID CELLS | Hematopoietic stem cells | RISE | MICROGLIA DERIVE | Mouse | Lineage tracing | Monocyte to macrophage differentiation | HEMATOPOIETIC STEM-CELLS | Tissue-resident macrophages | IL-7 RECEPTOR | FETAL MONOCYTES | STEADY-STATE | IL7R | LINEAGE | LIFE
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 10/2012, Volume 264, Issue 1, pp. 42 - 50
Although estrogen receptor (ER) agonists, such as estradiol and ethinylestradiol (EE2), cause cholestasis in mice, they also reduce the degree of liver injury... 
Chemical-induced liver injury | Estrogen receptor α | Drug-induced liver injury | Species differences | Monocyte to macrophage differentiation-associated 2 (Mmd2) | RAT-LIVER | ESTROGEN-RECEPTOR MODULATORS | REPERFUSION INJURY | ATELOCOLLAGEN | ALPHA | DELIVERY | SMALL INTERFERING RNA | THIOACETAMIDE | IN-VIVO | PHARMACOLOGY & PHARMACY | Estrogen receptor alpha | TOXICOLOGY | INDUCED HEPATOTOXICITY | Chemical and Drug Induced Liver Injury - prevention & control | Raloxifene Hydrochloride - pharmacology | Oligonucleotide Array Sequence Analysis | Mice, Inbred C57BL | Male | Ethinyl Estradiol - pharmacology | RNA, Messenger - metabolism | Mice, Inbred ICR | Mice, Knockout | Up-Regulation - drug effects | Animals | Estrogen Receptor alpha - agonists | Cell Differentiation - drug effects | Tamoxifen - pharmacology | Female | Macrophages - drug effects | Mice | Chemical and Drug Induced Liver Injury - pathology | RNA, Small Interfering - administration & dosage | Selective Estrogen Receptor Modulators - pharmacology | DNA microarrays | RNA | Analysis | Liver | Ethinyl estradiol | Tamoxifen | Macrophages | Estradiol | Index Medicus | selective estrogen receptor modulators | Estrogens | ethinylestradiol | Estrogen receptors | Bromobenzene | mRNA | siRNA | Gene expression | Diclofenac | Proteins | Thioacetamide | Monocytes | Acetaminophen | DNA | Raloxifene | Hepatotoxicity | Cholestasis | Injuries | INJURIES | MACROPHAGES | TAMOXIFEN | MONOCYTES | 60 APPLIED LIFE SCIENCES | MESSENGER-RNA | DRUGS | ESTRADIOL | LIVER | KNOCK-OUT REACTIONS | MICE | RECEPTORS
Journal Article
Frontiers in Immunology, ISSN 1664-3224, 11/2018, Volume 9, p. 2818
beta-Glucan derived from cell walls of Candida albicans is a potent immune modulator. It has been shown to induce trained immunity in monocytes via epigenetic... 
Candida albicans | β-glucan | monocyte to macrophage differentiation | trained immunity | monocyte survival | LIFE-SPAN | beta-glucan | DENDRITIC CELLS | IMMUNOLOGY | ADHESION | IN-VITRO | METABOLISM | PROGRAMS | EXPRESSION | INNATE IMMUNITY | BLOOD
Journal Article
Frontiers in Cell and Developmental Biology, 03/2016, Volume 4
Macrophages represent the primary human host response to pathogen infection and link the immediate defense to the adaptive immune system. Mature tissue... 
monocyte-to-macrophage differentiation | THP-1 cells | chemical proteomics | signaling | kinome | phosphoproteome
Journal Article
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, ISSN 2296-634X, 2016, Volume 4, p. 21
Macrophages represent the primary human host response to pathogen infection and link the immediate defense to the adaptive immune system. Mature tissue... 
monocyte-to-macrophage differentiation | signaling | kinome | THP-1 cells | chemical proteomics | DEVELOPMENTAL BIOLOGY | kinomics | phosphoproteome | CELL BIOLOGY | Cellular signal transduction | Macrophages | Observations | Health aspects | Mitogen-activated protein kinases
Journal Article