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Journal of Visualized Experiments, ISSN 1940-087X, 05/2016, Volume 2016, Issue 111
Journal Article
The Journal of Infectious Diseases, ISSN 0022-1899, 11/2013, Volume 208, Issue 10, pp. 1553 - 1560
Journal Article
Journal Article
Nature Reviews Drug Discovery, ISSN 1474-1776, 02/2012, Volume 11, Issue 2, pp. 125 - 140
Here, we discuss three RNA-based therapeutic technologies exploiting various oligonucleotides that bind to RNA by base pairing in a sequence-specific manner... 
SYSTEMIC DELIVERY | COLI-IN-VITRO | MORPHOLINO OLIGOMERS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | ESCHERICHIA-COLI | GENE-EXPRESSION | PHARMACOLOGY & PHARMACY | DUCHENNE MUSCULAR-DYSTROPHY | VIRUS-INFECTIONS | MOTOR-NEURON | CELL-CULTURES | PRE-MESSENGER-RNA | RNA, Small Interfering - genetics | RNA Interference - drug effects | Oligodeoxyribonucleotides, Antisense - pharmacology | Phosphorothioate Oligonucleotides - genetics | Gene Expression - drug effects | Morpholinos - genetics | Antiviral Agents - therapeutic use | Gene Expression - genetics | Muscular Dystrophy, Duchenne - drug therapy | Alternative Splicing - genetics | Humans | Morpholinos - therapeutic use | RNA, Messenger - genetics | beta-Thalassemia - genetics | Oligodeoxyribonucleotides, Antisense - therapeutic use | beta-Thalassemia - drug therapy | Anti-Bacterial Agents - therapeutic use | Alternative Splicing - drug effects | Animals | Myotonic Dystrophy - drug therapy | Myotonic Dystrophy - genetics | Muscular Dystrophy, Duchenne - genetics | Phosphorothioate Oligonucleotides - therapeutic use | Physiological aspects | Messenger RNA | Research | Gene expression | Health aspects | Oligonucleotides | Alternative splicing | Therapeutic applications | Duchenne's muscular dystrophy | RNA-mediated interference | Clinical trials | Recovery of function | Antisense oligonucleotides
Journal Article
Journal Article
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2017, Volume 1565, pp. 265 - 277
Journal Article
Journal Article
Journal Article
Viruses, ISSN 1999-4915, 11/2012, Volume 4, Issue 11, pp. 2806 - 2830
Journal Article
Development, ISSN 0950-1991, 08/2014, Volume 141, Issue 16, pp. 3103 - 4
Morpholino oligomers have been used widely and for many years in the zebrafish community to transiently knock down the function of target genes. It has often... 
Phenotype | Animals | Zebrafish | Morpholinos | Mutation | Genetic Techniques | Genome | CELLS | RERIO | ZEBRAFISH | GENE | EMBRYO | SPECIFICITY | TALENS | ANTISENSE | DEVELOPMENTAL BIOLOGY | MUTATIONS | NUCLEASE | Morpholinos - genetics | Genetic Techniques - trends
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2017, Volume 1565, pp. 1 - 15
Beginning with my concept in 1969 to treat disease at the nucleic acid level using antisense nucleic acids, antisense has evolved to the current Morpholino... 
Morpholino oligomers | Antisense | Anti-gene | Delivery | History | Animals | Oligonucleotides, Antisense - genetics | Research - history | Morpholinos - genetics | History, 20th Century | Humans | Morpholinos - therapeutic use | Inventions - history | Morpholinos - chemistry | Gene Knockdown Techniques | Genetic Therapy - methods
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2017, Volume 1565, pp. 39 - 50
Modifications at either end, both ends, or in-between the ends of a Morpholino oligo provide functional groups for further conjugation. Amino groups are the... 
Vis-Vivo-Morpholino | Morpholino oligo | Conjugation | End-modification | Functionalization | Amino groups | Amines - chemistry | Solid-Phase Synthesis Techniques | Animals | Oligonucleotides, Antisense - chemical synthesis | Morpholinos - chemical synthesis | Humans | Oligonucleotides, Antisense - chemistry | Morpholinos - chemistry
Journal Article