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British Journal of Clinical Pharmacology, ISSN 0306-5251, 08/2014, Volume 78, Issue 2, pp. 329 - 342
AIMS The urinary coproporphyrin I/(I + III) ratio may be a surrogate for MRP2 activity. We conducted a prospective study in patients receiving methotrexate... 
drug transporters | MRP2 | ABCC2 | drug–drug interactions | benzimidazole | methotrexate | multi‐drug resistance protein‐2 | population pharmacokinetics | MRP2 (multi-drug resistance protein-2)/ABCC2 | drug-drug interactions | ABCC2 MRP2 | GENETIC POLYMORPHISMS | HIGH-DOSE METHOTREXATE | HEPATIC-UPTAKE | ORGANIC ANION-TRANSPORTER | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | BILIARY-EXCRETION | IN-VIVO | PHARMACOLOGY & PHARMACY | CANCER RESISTANCE PROTEIN | Biomarkers - urine | Antimetabolites, Antineoplastic - pharmacokinetics | Humans | Methotrexate - pharmacokinetics | Middle Aged | Male | Metabolic Clearance Rate | Methotrexate - toxicity | Methotrexate - therapeutic use | Antimetabolites, Antineoplastic - administration & dosage | Lymphoma - urine | Young Adult | Lymphoma - drug therapy | Aged, 80 and over | Adult | Female | Multidrug Resistance-Associated Proteins - genetics | Coproporphyrins - urine | Lymphoma - genetics | Antimetabolites, Antineoplastic - therapeutic use | Models, Biological | Adolescent | Antimetabolites, Antineoplastic - toxicity | Methotrexate - administration & dosage | Aged | Polymorphism, Single Nucleotide | Infusions, Intravenous | Multidrug Resistance-Associated Proteins - metabolism | Drug resistance | Methotrexate | Analysis | Index Medicus | MRP2 (multi-drug resistance protein-2) | Pharmacokinetics
Journal Article
Journal Article
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY, ISSN 1742-5255, 07/2008, Volume 4, Issue 7, pp. 923 - 939
Journal Article
Plant Journal, ISSN 0960-7412, 03/2010, Volume 61, Issue 5, pp. 728 - 740
Journal Article
Brain, ISSN 0006-8950, 9/2009, Volume 132, Issue 9, pp. 2517 - 2530
Escalation therapy with mitoxantrone (MX) in highly active multiple sclerosis is limited by partially dose-dependent side-effects. Predictors of therapeutic... 
Experimental autoimmune encephalomyelitis | Pharmacogenetics | Escalation therapy | Multi-drug resistance transporter | CRITERIA | CELLS | MULTICENTER | RESISTANCE PROTEIN | DEXRAZOXANE | NEUROSCIENCES | CLINICAL NEUROLOGY | DRUG EFFLUX TRANSPORTERS | INDUCED CARDIOTOXICITY | experimental autoimmune encephalomyelitis | THERAPEUTIC-EFFICACY | multi-drug resistance transporter | LEUKEMIA | EXPRESSION | escalation therapy | pharmacogenetics | Glucocorticoids - therapeutic use | Humans | Middle Aged | Male | ATP-Binding Cassette Transporters - genetics | Adult | Female | Retrospective Studies | Encephalomyelitis, Autoimmune, Experimental - genetics | Drug Therapy, Combination | Neoplasm Proteins - genetics | Mitoxantrone - adverse effects | Mitoxantrone - therapeutic use | Multiple Sclerosis - metabolism | ATP Binding Cassette Transporter, Subfamily G, Member 2 | ATP Binding Cassette Transporter, Subfamily B, Member 1 - biosynthesis | Drug Resistance, Multiple - genetics | Neoplasm Proteins - biosynthesis | Encephalomyelitis, Autoimmune, Experimental - drug therapy | Gene Frequency | RNA, Messenger - genetics | Gene Expression Regulation | Genotype | Multiple Sclerosis - genetics | Treatment Outcome | Genetic Markers | ATP Binding Cassette Transporter, Subfamily B | ATP Binding Cassette Transporter, Subfamily B, Member 1 - genetics | ATP-Binding Cassette Transporters - biosynthesis | Animals | Mice | Polymorphism, Single Nucleotide | Mitoxantrone - pharmacokinetics | Multiple Sclerosis - drug therapy | Index Medicus | Abridged Index Medicus
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 11/2010, Volume 299, Issue 5, pp. C1100 - C1109
Ni Z, Bikadi Z, Cai X, Rosenberg MF, Mao Q. Transmembrane helices 1 and 6 of the human breast cancer resistance protein (BCRP/ABCG2): identification of polar... 
Multi-drug resistance | Adenosine 5′-triphosphate-binding cassette efflux transporter | Site-directed mutagenesis | Structure-function of adenosine 5′-triphosphate-binding cassette transporter | adenosine 5 '-triphosphate-binding cassette efflux transporter | site-directed mutagenesis | 5 '-triphosphate-binding cassette transporter | multidrug resistance | PHYSIOLOGY | structure-function of adenosine | MEMBRANE | HALF-TRANSPORTER | MUTATIONAL ANALYSIS | P-GLYCOPROTEIN | CELL BIOLOGY | SUBSTRATE-SPECIFICITY | CONFORMATIONAL-CHANGES | AMINO-ACID-RESIDUES | BINDING | ATP | ABCG2 | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Humans | Molecular Sequence Data | Prazosin - metabolism | Drug Resistance, Neoplasm | Neoplasm Proteins - metabolism | Breast Neoplasms - metabolism | ATP-Binding Cassette Transporters - chemistry | ATP-Binding Cassette Transporters - genetics | ATP-Binding Cassette Transporters - metabolism | Female | Cell Membrane - metabolism | Neoplasm Proteins - genetics | Amino Acid Sequence | Cell Line | Mutagenesis, Site-Directed | Protein Structure, Secondary | Models, Molecular | Neoplasm Proteins - chemistry | Adrenergic alpha-Antagonists - metabolism | Point Mutation | Pharmaceutical Preparations - metabolism | Sequence Alignment | Animals | Biological Transport - physiology | Care and treatment | Physiological aspects | Breast cancer | Drug resistance | Drug therapy | Properties | Adenosine triphosphatase | Cancer | Proteins | Membranes | Kidneys | Mutation | Cells | Binding sites | Index Medicus | adenosine 5′-triphosphate-binding cassette efflux transporter | structure-function of adenosine 5′-triphosphate-binding cassette transporter | Membrane Transporters, Ion Channels and Pumps
Journal Article
Journal Article
Annual review of biophysics, ISSN 1936-122X, 2014, Volume 43, pp. 93 - 117
Infections caused by bacteria remain a leading cause of death worldwide. While antibiotics remain a key clinical therapy, their effectiveness has been severely... 
multi-drug resistance | CusCFBA efflux system | heavy metal resistance | resistance-nodulation-cell division
Journal Article
CURRENT TOPICS IN MEDICINAL CHEMISTRY, ISSN 1568-0266, 2019, Volume 19, Issue 10, pp. 874 - 885
Journal Article
Journal of Drug Delivery Science and Technology, ISSN 1773-2247, 2010, Volume 20, Issue 2, pp. 89 - 99
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 05/2015, Volume 133, Issue 4, pp. 558 - 571
Journal Article