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Nature: international weekly journal of science, ISSN 0028-0836, 01/2014, Volume 506, Issue 7487, pp. 240 - 244
textabstractCells of the osteoblast lineage affect the homing and the number of long-term repopulating haematopoietic stem cells, haematopoietic stem cell... 
PROGENITOR CELLS | MULTIDISCIPLINARY SCIENCES | ACUTE LYMPHOBLASTIC-LEUKEMIA | BONE-MARROW NICHE | NOTCH ACTIVATION | STEM-CELL NICHE | MYELOID-LEUKEMIA | MICE | DIFFERENTIATION | EXPRESSION | MYELODYSPLASTIC SYNDROMES | Osteoblasts - secretion | Receptors, Notch - metabolism | Humans | Leukemia, Myeloid, Acute - metabolism | Hematopoietic Stem Cells - pathology | Anemia - pathology | Male | Cell Differentiation - genetics | Intercellular Signaling Peptides and Proteins - metabolism | Membrane Proteins - deficiency | Anemia - genetics | Cell Nucleus - metabolism | Tumor Microenvironment - genetics | Cell Transformation, Neoplastic - genetics | Serrate-Jagged Proteins | Base Sequence | Female | Membrane Proteins - metabolism | Intercellular Signaling Peptides and Proteins - deficiency | Jagged-1 Protein | Calcium-Binding Proteins - metabolism | Myelodysplastic Syndromes - metabolism | Signal Transduction | Leukemia, Myeloid, Acute - pathology | Membrane Proteins - genetics | Intercellular Signaling Peptides and Proteins - genetics | Calcium-Binding Proteins - deficiency | Hematopoietic Stem Cells - metabolism | Mutation - genetics | beta Catenin - metabolism | beta Catenin - genetics | Anemia - metabolism | Cell Lineage | Osteoblasts - pathology | Animals | Chromosome Aberrations | Myeloid Cells - metabolism | Ligands | Mice | Myelodysplastic Syndromes - genetics | Myeloid Cells - pathology | Cell Transformation, Neoplastic - pathology | Myelodysplastic Syndromes - pathology | Osteoblasts - metabolism | Calcium-Binding Proteins - genetics | Leukemia, Myeloid, Acute - genetics | Index Medicus
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 671 - 15
Journal Article
HEPATOLOGY, ISSN 0270-9139, 12/2016, Volume 64, Issue 6, pp. 2047 - 2061
CTNNB1 mutations activating beta-catenin are frequent somatic events in hepatocellular carcinoma (HCC) and adenoma (HCA), particularly associated with a risk... 
GENE | THERAPEUTIC TARGETS | CLASSIFICATION | UNIPARENTAL DISOMY | HUMAN HEPATOCELLULAR CARCINOMAS | GASTROENTEROLOGY & HEPATOLOGY | CANCER | SOMATIC MUTATIONS | ACTIVATING MUTATIONS | ADENOMAS | HEPATOCARCINOGENESIS
Journal Article
AMERICAN JOURNAL OF HUMAN GENETICS, ISSN 0002-9297, 09/2015, Volume 97, Issue 3, pp. 445 - 456
The link of chromatin remodeling to both neurodevelopment and cancer has recently been highlighted by the identification of mutations affecting BAF... 
TARGET | CONDUCTIN/AXIN2 | GENE | SWI/SNF-RELATED COMPLEXES | GENETICS & HEREDITY | SUBUNITS | MUTATIONS | CELL-CYCLE CONTROL | BETA-CATENIN | UP-REGULATION | COMPARABILITY
Journal Article
Digestive Diseases and Sciences, ISSN 0163-2116, 9/2019, Volume 64, Issue 9, pp. 2591 - 2599
Wnt ligand binding initiates the interaction between Frizzled and Dvl proteins. However, the regulation of Frizzled–Dvl proteins interaction remains largely... 
Biochemistry, general | Medicine & Public Health | Hepatology | Gastroenterology | Beta-catenin/TCF signaling | Oncology | Hepatocellular carcinoma | WDR34 | Transplant Surgery | Cell growth and migration | Proteins | Immunohistochemistry | Hepatoma | Protein binding | Liver cancer | Cell growth | Genes | Cell cycle | Science | Ligands | Tumorigenesis | Mutation | Bladder cancer | Index Medicus | Abridged Index Medicus
Journal Article
Experimental Cell Research, ISSN 0014-4827, 09/2018, Volume 370, Issue 2, pp. 461 - 467
Over-activation of beta-catenin/TCF signaling is very common in the progression of hepatocellular carcinoma (HCC). The molecular mechanisms leading to the... 
Beta-catenin/TCF signaling | Hepatocellular carcinoma | CDK7 | Cell growth and migration | APOPTOSIS | METASTASIS | CELL-CYCLE ARREST | CANCER | CELL BIOLOGY | ONCOLOGY | PATHWAY | MUTATION | GROWTH | EXPRESSION | MET | Medical colleges | Medical research | Chemotherapy | Medicine, Experimental | Development and progression | Hepatoma | Molecular biology | Cancer
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2016, Volume 11, Issue 8, pp. e0161682 - e0161682
Wnt/beta-catenin signaling is relatively understudied in immunity and autoimmunity. beta-catenin blocks inflammatory mediators and favors tolerogenic dendritic... 
ADHESION | DENDRITIC CELLS | GENE | PATHWAY | COLORECTAL-CANCER | MULTIDISCIPLINARY SCIENCES | MICE | E-CADHERIN | MUTATIONS | WNT | NF-KAPPA-B | Leukocytes - pathology | Spleen - immunology | Axin Protein - genetics | Dendritic Cells - immunology | Humans | Dendritic Cells - pathology | Male | Wnt Proteins - metabolism | Axin Protein - metabolism | Intercellular Signaling Peptides and Proteins - blood | Leukocytes - immunology | beta Catenin - immunology | Wnt Proteins - genetics | Axin Protein - immunology | Gene Deletion | Lupus Erythematosus, Systemic - immunology | Female | Spleen - pathology | Macrophages - immunology | Wnt Signaling Pathway | Disease Models, Animal | Follistatin-Related Proteins - genetics | Follistatin-Related Proteins - metabolism | Macrophages - pathology | Mice, Inbred C57BL | beta Catenin - deficiency | Gene Expression Regulation | Intercellular Signaling Peptides and Proteins - genetics | Mice, Transgenic | beta Catenin - genetics | Wnt Proteins - immunology | Animals | Follistatin-Related Proteins - immunology | Lupus Erythematosus, Systemic - genetics | Mice | Lupus Erythematosus, Systemic - pathology | Intercellular Signaling Peptides and Proteins - immunology | Autoimmunity | Care and treatment | Systemic lupus erythematosus | Dendritic cells | Analysis | Hepatoma | Diagnosis | Research | Macrophages | Wnt protein | Disease | Leukocytes | Immunity | Cell adhesion & migration | β-catenin | Engineering | Immunology | Clonal deletion | Rodents | Deletion | Biomedical engineering | Lupus | Myeloid cells | Kidneys | Internal medicine | Rheumatic diseases | Inflammation | Preempting | Patients | Human subjects | White blood cells | Medicine | Serum levels | Signaling | Chronic conditions | Insects | Mutation | Autoimmune diseases | Dkk1 protein | Index Medicus
Journal Article
BRITISH JOURNAL OF PHARMACOLOGY, ISSN 0007-1188, 12/2017, Volume 174, Issue 24, pp. 4611 - 4636
The Wnt/beta-catenin signalling pathway is pivotal for stem cell function and the control of cellular differentiation, both during embryonic development and... 
ADENOMATOUS POLYPOSIS-COLI | STERILE ALPHA MOTIF | MESSENGER-RNA EXPRESSION | STRUCTURAL BASIS | WNT PATHWAY | SMALL-MOLECULE INHIBITORS | MUTATION CLUSTER REGION | PHARMACOLOGY & PHARMACY | DOMAIN POLYMERIZATION | BETA-CATENIN | STRUCTURE-BASED DESIGN
Journal Article
Journal Article
Nature Neuroscience, ISSN 1097-6256, 11/2003, Volume 6, Issue 11, pp. 1169 - 1177
Regulated growth and arborization of dendritic processes are critical to the formation of functional neuronal networks. Here we identify beta-catenin as a... 
NMDA RECEPTOR | GENE | IN-VIVO | GROWTH | TRANSCRIPTION | RHO GTPASES | CELL-ADHESION | WNT | HIPPOCAMPAL-NEURONS | NEUROSCIENCES | N-CADHERIN | Green Fluorescent Proteins | Cadherins - metabolism | Embryo, Mammalian | Humans | 2-Amino-5-phosphonovalerate - pharmacology | Wnt Proteins | Anesthetics, Local - pharmacology | Trans-Activators - physiology | Drug Interactions | Tetrodotoxin - pharmacology | Animals, Newborn | Dendrites - drug effects | Rats | Excitatory Amino Acid Antagonists - pharmacology | Rats, Sprague-Dawley | Signal Transduction - drug effects | rho GTP-Binding Proteins - metabolism | Mutation | Morphogenesis - physiology | Epitopes - metabolism | Sodium Chloride - pharmacology | Culture Media, Conditioned - pharmacology | Neurons - cytology | Kidney | DNA-Binding Proteins - metabolism | Dose-Response Relationship, Drug | Lymphoid Enhancer-Binding Factor 1 | Transfection | Gene Expression Regulation, Developmental | Dendrites - physiology | Potassium Chloride - pharmacology | Cytoskeletal Proteins - physiology | Neurons - drug effects | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - antagonists & inhibitors | Nifedipine - pharmacology | beta Catenin | Cells, Cultured | Zebrafish Proteins | Probability | Calcium Channel Blockers - pharmacology | Hippocampus - cytology | Transcription Factors - metabolism | Hippocampus - metabolism | Animals | Morphogenesis - drug effects | Signal Transduction - physiology | Calcium-Calmodulin-Dependent Protein Kinases - metabolism | Luminescent Proteins - metabolism | Index Medicus
Journal Article