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1. Full Text Nucleic acid detection with CRISPR-Cas13a/C2c2
by Gootenberg, Jonathan S and Abudayyeh, Omar O and Lee, Jeong Wook and Essletzbichler, Patrick and Dy, Aaron J and Joung, Julia and Verdine, Vanessa and Donghia, Nina and Daringer, Nichole M and Freije, Catherine A and Myhrvold, Cameron and Bhattacharyya, Roby P and Livny, Jonathan and Regev, Aviv and Koonin, Eugene V and Hung, Deborah T and Sabeti, Pardis C and Collins, James J and Zhang, Feng
Science (American Association for the Advancement of Science), ISSN 0036-8075, 04/2017, Volume 356, Issue 6336, pp. 438 - 442
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Circulating Tumor DNA - analysis | Zika Virus - genetics | Circulating Tumor DNA - genetics | Ribonucleases - chemistry | Humans | Bacterial Proteins - chemistry | RNA, Viral - analysis | RNA Cleavage | Zika Virus - isolation & purification | Dengue Virus - genetics | Bacteria - isolation & purification | RNA, Viral - genetics | Zika Virus Infection - diagnosis | Neoplasms - genetics | Point-of-Care Systems | Clustered Regularly Interspaced Short Palindromic Repeats | DNA, Bacterial - analysis | Bacteria - pathogenicity | Dengue Virus - isolation & purification | Mutation | Dengue - diagnosis | Methods | Nucleotide sequencing | DNA sequencing | Vector-borne diseases | Pathogens | CRISPR | Target recognition | Nucleotide sequence | Dengue | Viruses | Zika virus | Nucleic acids | Ribonuclease | Recombinase | Ribonucleic acid--RNA | Sensitivity | Genotyping | Reagents | Bacteria | Deoxyribonucleic acid--DNA | Index Medicus | Amplification | Ribonucleic acids | Deoxyribonucleic acid
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2. Full Text NMR Detection of Structures in the HIV-1 5'-Leader RNA That Regulate Genome Packaging
by Kun Lu and Xiao Heng and Lianko Garyu and Sarah Monti and Eric L. Garcia and Siarhei Kharytonchyk and Bilguujin Dorjsuren and Gowry Kulandaivel and Simonne Jones and Atheeth Hiremath and Sai Sachin Divakaruni and Courtney LaCotti and Shawn Barton and Daniel Tummillo and Azra Hosic and Kedy Edme and Sara Albrecht and Alice Telesnitsky and Michael F. Summers
Science (American Association for the Advancement of Science), ISSN 0036-8075, 10/2011, Volume 334, Issue 6053, pp. 242 - 245
RNA | REPORTS | Chemical bases | Packaging | Dimers | Genomes | Gene expression regulation | Nuclear magnetic resonance | Dimerization | Genetic mutation | Monomers | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Replicative cycle, interference, host-virus relations, pathogenicity, miscellaneous strains | Biological and medical sciences | Microbiology | Virology | Genome, Viral | Protein Biosynthesis | Mutagenesis, Site-Directed | Codon, Initiator | HIV-1 - genetics | Virus Assembly | Human Immunodeficiency Virus Proteins - metabolism | gag Gene Products, Human Immunodeficiency Virus - metabolism | HIV-1 - physiology | RNA, Viral - chemistry | RNA, Viral - genetics | Base Pairing | Nucleocapsid Proteins - metabolism | 5' Untranslated Regions | Genes, gag | Nuclear Magnetic Resonance, Biomolecular | Protein Binding | Nucleic Acid Conformation | Binding Sites | Usage | Genetic research | Genetic aspects | Research | HIV (Viruses) | Structure | Methods | Proteins | Nuclear magnetic resonance--NMR | Ribonucleic acid--RNA | Human immunodeficiency virus--HIV | Index Medicus | Base pairs
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3. Full Text Plasma ctDNA Analysis for Detection of the EGFR T790M Mutation in Patients with Advanced Non–Small Cell Lung Cancer
by Jenkins, Suzanne and Yang, James C-H and Ramalingam, Suresh S and Yu, Karen and Patel, Sabina and Weston, Susie and Hodge, Rachel and Cantarini, Mireille and Jänne, Pasi A and Mitsudomi, Tetsuya and Goss, Glenwood D
Journal of thoracic oncology, ISSN 1556-0864, 07/2017, Volume 12, Issue 7, pp. 1061 - 1070
tumor tissue biopsy | Roche cobas EGFR Mutation Test | osimertinib | MiSeq next-generation sequencing | circulating tumor DNA | Respiratory System | Oncology | Life Sciences & Biomedicine | Science & Technology | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Receptor, Epidermal Growth Factor - genetics | DNA, Neoplasm - blood | Carcinoma, Non-Small-Cell Lung - genetics | Humans | Female | Lung Neoplasms - pathology | Male | Mutation
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4. Full Text Prevention and early detection of prostate cancer
by Cuzick, Jack, Prof and Thorat, Mangesh A, MBBS and Andriole, Gerald, Prof and Brawley, Otis W, Prof and Brown, Powel H, Prof and Culig, Zoran, MD and Eeles, Rosalind A, Prof and Ford, Leslie G, MD and Hamdy, Freddie C, Prof and Holmberg, Lars, Prof and Ilic, Dragan, PhD and Key, Timothy J, Prof and Vecchia, Carlo La, Prof and Lilja, Hans, Prof and Marberger, Michael, Prof and Meyskens, Frank L, Prof and Minasian, Lori M, MD and Parker, Chris, MD and Parnes, Howard L, MD and Perner, Sven, Prof and Rittenhouse, Harry, PhD and Schalken, Jack, Prof and Schmid, Hans-Peter, Prof and Schmitz-Dräger, Bernd J, Prof and Schröder, Fritz H, Prof and Stenzl, Arnulf, Prof and Tombal, Bertrand, Prof and Wilt, Timothy J, Prof and Wolk, Alicja, Prof
The lancet oncology, ISSN 1470-2045, 2014, Volume 15, Issue 11, pp. e484 - e492
Hematology, Oncology and Palliative Medicine | Life Sciences & Biomedicine | Oncology | Science & Technology | Immunohistochemistry | Life Style | Prognosis | Age Factors | Early Detection of Cancer - methods | Risk Reduction Behavior | Biomarkers, Tumor - analysis | Humans | Middle Aged | Risk Factors | Male | Prostatic Neoplasms - diagnosis | Evidence-Based Medicine | Prostate-Specific Antigen - blood | Prostatic Neoplasms - therapy | Neoplasm Invasiveness - pathology | Primary Prevention - methods | Aged, 80 and over | Aged | Biopsy, Needle | Prostatic Neoplasms - prevention & control | Prevention | Diagnosis | Prostate cancer | Cancer | Index Medicus | prostate cancer | risk factors | screening | prevention | PSA | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Cancer and Oncology | Medicin och hälsovetenskap | Cancer och onkologi
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5. Full Text Validation of Biomarkers for Early Detection of Pancreatic Cancer: Summary of the Alliance of Pancreatic Cancer Consortia for Biomarkers for Early Detection Workshop
by Young, Matthew R and Wagner, Paul D and Ghosh, Sharmistha and Rinaudo, Jo Ann and Baker, Stuart G and Zaret, Kenneth S and Goggins, Michael and Srivastava, Sudhir
Pancreas, ISSN 0885-3177, 02/2018, Volume 47, Issue 2, pp. 135 - 141
PDAC | early detection | biomarkers | validation | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Biomarkers, Tumor - blood | Pancreatic Neoplasms - blood | Genetic Predisposition to Disease - genetics | Early Detection of Cancer - methods | Pancreatic Neoplasms - diagnosis | Humans | Sensitivity and Specificity | Pancreatic Neoplasms - genetics | Biomarkers, Tumor - genetics | Mutation | Research | Pancreatic cancer | Analysis | Risk factors | Prevalence studies (Epidemiology) | Index Medicus
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6. Full Text Detecting Natural Selection in Genomic Data
by Vitti, Joseph J and Grossman, Sharon R and Sabeti, Pardis C
Annual review of genetics, ISSN 0066-4197, 11/2013, Volume 47, Issue 1, pp. 97 - 120
population genetics | adaptation | evolutionary genomics | selective sweeps | genome scans | Evolutionary genomics | Genome scans | Population genetics | Adaptation | Selective sweeps | Multifactorial Inheritance - genetics | Gene Frequency | Genomics | Humans | Mutation Rate | Genotyping Techniques | Forecasting | Sequence Analysis, DNA | Linkage Disequilibrium | Selection, Genetic - genetics | Phenotype | Animals | Genetics, Population - methods | Adaptation, Physiological - genetics | Alleles | Models, Genetic | Mutation | Amino Acid Substitution | Evolution, Molecular | Statistical methods | Research | Natural selection | Evolution | Index Medicus
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