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1. Full Text Grass pollen immunotherapy induces Foxp3-expressing CD4+ CD25+ cells in the nasal mucosa
by Radulovic, Suzana, MD and Jacobson, Mikila R., PhD and Durham, Stephen R., MD and Nouri-Aria, Kayhan T., PhD
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2008, Volume 121, Issue 6, pp. 1467 - 1472.e1
Background Regulatory T (Treg) cells play an important role in controlling allergic inflammation. The transcription factor Foxp3 regulates the development and... 
Allergy and Immunology | grass pollen immunotherapy | CD4 +CD25 + Treg cells | Foxp3 | IL-10 | hay fever/allergic rhinitis | CD4 | Treg cells | CD25 | TGF-BETA | IMMUNOLOGY | INTESTINAL INFLAMMATION | RHINITIS | CD4(+)CD25(+) Treg cells | MESSENGER-RNA | ALLERGY | EXPANSION | REGULATORY T-CELLS | EXPRESSION | MOLECULAR-MECHANISMS | Immunohistochemistry | T-Lymphocyte Subsets - immunology | Forkhead Transcription Factors - biosynthesis | Poaceae - immunology | T-Lymphocytes, Regulatory - metabolism | Humans | Palatine Tonsil - immunology | Palatine Tonsil - cytology | Randomized Controlled Trials as Topic | T-Lymphocytes, Regulatory - immunology | Rhinitis, Allergic, Seasonal - prevention & control | Nasal Mucosa - immunology | T-Lymphocyte Subsets - metabolism | Nasal Mucosa - cytology | Interleukin-10 - biosynthesis | Desensitization, Immunologic | Transcription factors | Peptides | Lymphocytes | Pollen | Grasses | Seasons | Allergies | Asthma
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2. Full Text Barrier function of the nasal mucosa in health and type‐2 biased airway diseases
by Zhang, N and Van Crombruggen, K and Gevaert, E and Bachert, C
Allergy, ISSN 0105-4538, 03/2016, Volume 71, Issue 3, pp. 295 - 307
The mucosal lining of the upper airways represents the outer surface of the body to the ambient air and its contents and is prepared for it as the first line... 
nasal epithelial barrier | allergic rhinitis | eosinophil extracellular traps | immune response | chronic rhinosinusitis with nasal polyps | EPITHELIAL BARRIER | DENDRITIC CELLS | ION-TRANSPORT | BETA-DEFENSINS | INNATE LYMPHOID-CELLS | IMMUNOLOGY | CHRONIC RHINOSINUSITIS PATIENTS | ALLERGY | IMMUNE-RESPONSES | STAPHYLOCOCCUS-AUREUS | DIMINISHED LEVELS | Eosinophils - metabolism | Respiratory Tract Infections - metabolism | Cytokines - metabolism | Hypersensitivity - therapy | Extracellular Traps - metabolism | Extracellular Traps - microbiology | Humans | Immunity, Mucosal | Neutrophils - immunology | Antimicrobial Cationic Peptides - metabolism | Immunity, Innate | Eosinophils - immunology | Microbiota | Nasal Mucosa - microbiology | Animals | Extracellular Traps - immunology | Respiratory Tract Infections - therapy | Hypersensitivity - metabolism | Hypersensitivity - etiology | Nasal Mucosa - immunology | Respiratory Tract Infections - etiology | Chemokines - metabolism | Nasal Mucosa - metabolism | Neutrophils - metabolism | T cell receptors | Rodents | Respiratory diseases | Medical immunity
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3. Full Text Melanotic PEComa of the Sinonasal Mucosa With NONO-TFE3 Fusion: An Elusive Mimic of Sinonasal Melanoma
by McGregor, Stephanie M and Alikhan, Mir B and John, Rahel A and Kotler, Howard and Bridge, Julia A and Mujacic, Ibro and Kadri, Sabah and Segal, Jeremy and Krausz, Thomas
The American Journal of Surgical Pathology, ISSN 0147-5185, 05/2017, Volume 41, Issue 5, pp. 717 - 722
Perivascular epithelioid cell neoplasms (PEComas) are a family of mesenchymal tumors with features of both smooth muscle and melanocytic differentiation, with... 
PECOMA | Melanoma | TFE3 | SURGERY | NEOPLASM | CANCERS | PEComa | melanoma | MALIGNANT-MELANOMA | PATHOLOGY | TFE3 GENE | NASAL CAVITY | SPECTRUM | CELL TUMORS PECOMAS | EXPRESSION | CARCINOMA | Immunohistochemistry | Nose Neoplasms - chemistry | Predictive Value of Tests | RNA-Binding Proteins - genetics | Humans | Middle Aged | Nasal Mucosa - pathology | Melanins - analysis | Melanoma - genetics | Octamer Transcription Factors - genetics | Female | Perivascular Epithelioid Cell Neoplasms - chemistry | Melanoma - chemistry | Diagnosis, Differential | Nose Neoplasms - pathology | Biomarkers, Tumor - analysis | Gene Fusion | In Situ Hybridization, Fluorescence | Melanoma - pathology | Nose Neoplasms - genetics | Sequence Analysis, DNA | Perivascular Epithelioid Cell Neoplasms - pathology | Nuclear Matrix-Associated Proteins - genetics | Biopsy | Perivascular Epithelioid Cell Neoplasms - genetics | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - genetics | Nasal Mucosa - chemistry | Biomarkers, Tumor - genetics
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4. Full Text Expression of 11β-hydroxysteroid dehydrogenase 1 and 2 in patients with chronic rhinosinusitis and their possible contribution to local glucocorticoid activation in sinus mucosa
by Jun, Young Joon, MD and Park, Se Jin, MD and Kim, Tae Hoon, MD and Lee, Seung Hoon, MD and Lee, Ki Jeong, MD and Hwang, Soo Min, MD and Lee, Sang Hag, MD, PhD
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2014, Volume 134, Issue 4, pp. 926 - 934.e6
Background It has been suggested that glucocorticoids might act in target tissues to increase their own intracellular availability in response to inflammatory... 
Allergy and Immunology | cortisol | 11β-Hydroxysteroid dehydrogenase 1 | glucocorticoid | chronic rhinosinusitis with nasal polyps | CYP11A1 | CYP11B1 | 11β-hydroxysteroid dehydrogenase 2 | chronic rhinosinusitis without nasal polyps | CYP11A1 chronic rhinosinusitis with nasal polyps | glucocorticoid cortisol | LOCALIZATION | STIMULATION | HUMAN LUNG | 11 beta-Hydroxysteroid dehydrogenase 1 | IMMUNOLOGY | INACTIVATION | METABOLISM | ALLERGY | chronic rhinosinusitis with nasal polyps | GENE-EXPRESSION | 11 beta-hydroxysteroid dehydrogenase 2 | TYPE-1 | CORTICOSTEROIDS | MODULATION | Nasal Polyps - immunology | RNA, Small Interfering - genetics | Rhinitis - immunology | Cholesterol Side-Chain Cleavage Enzyme - metabolism | Humans | Cells, Cultured | Gene Expression Regulation | Hydrocortisone - metabolism | 11-beta-Hydroxysteroid Dehydrogenase Type 1 - genetics | Cholesterol Side-Chain Cleavage Enzyme - genetics | Hydrocortisone - genetics | 11-beta-Hydroxysteroid Dehydrogenase Type 1 - metabolism | Glucocorticoids - metabolism | Nasal Mucosa - immunology | Sinusitis - immunology | Epithelial Cells - immunology | 11-beta-Hydroxysteroid Dehydrogenase Type 2 - metabolism | 11-beta-Hydroxysteroid Dehydrogenase Type 2 - genetics | Chronic Disease | Cytokines - immunology
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5. Full Text IL-25/IL-33–responsive TH2 cells characterize nasal polyps with a default TH17 signature in nasal mucosa
by Lam, Emily P.S and Kariyawasam, Harsha H and Rana, Batika M.J and Durham, Stephen R and McKenzie, Andrew N.J and Powell, Nicholas and Orban, Nara and Lennartz-Walker, Melissa and Hopkins, Claire and Ying, Sun and Rimmer, Joanne and Lund, Valerie J and Cousins, David J and Till, Stephen J
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 05/2016, Volume 137, Issue 5, pp. 1514 - 1524
Chronic rhinosinusitis with nasal polyposis (CRSwNP) in Western countries is characterized by eosinophilia, IgE production, and T 2 cytokine expression. Type 2... 
ST2 | TH2 cells | microarray | Chronic rhinosinusitis with nasal polyps | IL-17RB | nasal mucosa | TH17 cells | IL-25 | T-cell phenotype | IL-33 | T-cell receptor Vβ repertoire | 2 cells | 17 cells | Nasal Polyps - immunology | Rhinitis - immunology | Eosinophilia - immunology | Nasal Mucosa - immunology | Sinusitis - immunology | Humans | Interleukin-17 - immunology | Th17 Cells - immunology | Th2 Cells - immunology | Chronic Disease | Interleukin-33 - immunology | Studies | Cell culture | Genotype & phenotype | Cytokines | Lymphocytes | Cloning | T cell receptors | Gene expression | CRTH2, Chemoattractant receptor-homologous molecule expressed on TH2 cells | CDR3, Complementarity-determining region 3 | ILC2, Type 2 innate lymphoid cell | AIM2, Absent in melanoma 2 | TCR Vβ, T-cell receptor variable β-chain | CRSwNP, Chronic rhinosinusitis with nasal polyposis | Mechanisms of Allergy and Clinical Immunology
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6. Full Text The human olfactory mucosa
by Escada, Pedro Alberto and Lima, Carlos and Da Silva, José Madeira
European Archives of Oto-Rhino-Laryngology, ISSN 0937-4477, 11/2009, Volume 266, Issue 11, pp. 1675 - 1680
Studies of the tissues of the human olfactory mucosa have been performed to investigate olfactory dysfunction and, more recently, olfactory mucosa has... 
Nervous system diseases | Nasal cavity | Biopsy | Humans | Nerve regeneration | Olfactory mucosa | STEM-CELLS | ALZHEIMERS-DISEASE | RECEPTOR NEURONS | HUMAN NASAL-MUCOSA | GLOBOSE BASAL-CELLS | SENSORY NEURONS | ENSHEATHING CELL TRANSPLANTATION | EPITHELIUM | OTORHINOLARYNGOLOGY | SPINAL-CORD-INJURY | Olfactory Mucosa - pathology | Olfactory Mucosa - surgery | Olfactory Mucosa - physiopathology | Stem cells
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7. Full Text Herpes Simplex Virus Type 1 Shedding in Tears and Nasal and Oral Mucosa of Healthy Adults
by Ramchandani, Meena and Kong, Marlene and Tronstein, Elizabeth and Selke, Stacy and Mikhaylova, Anna and Magaret, Amalia and Huang, Meei-Li and Johnston, Christine and Corey, Lawrence and Wald, Anna
Sexually Transmitted Diseases, ISSN 0148-5717, 12/2016, Volume 43, Issue 12, pp. 756 - 760
BACKGROUNDHerpes simplex virus type 1 (HSV-1) is prevalent worldwide and causes mucocutaneous infections of the oral area. We aimed to define the frequency and... 
WOMEN | INFECTIOUS DISEASES | HSV-1 | ASSAY | DNA | CAVITY | GENITAL HERPES | RABBIT | RAPIDLY CLEARED EPISODES | Humans | Conjunctiva - virology | Male | Virus Shedding | Young Adult | Herpes Simplex - virology | Herpesvirus 1, Human - physiology | Mouth Mucosa - virology | Adult | Female | Herpesvirus 1, Human - genetics | Herpesvirus 1, Human - immunology | Sexual Partners | Tears - virology | Nasal Mucosa - virology | Tearing | Distribution | Physiological aspects | Virulence (Microbiology) | Observations | Health aspects | Herpes simplex virus | Oral mucosa | Immunoassay | Shedding | Mucosa | Herpes simplex | Viruses | Activation | Conjunctiva | Risk factors | Polymerase chain reaction | Body fluids | Oral cavity | Disease transmission | Herpes viruses | Nose | Adults | Lesions | Sexual partners | Viral infections | Tears | Deoxyribonucleic acid--DNA | Herpes Simplex-1 (HSV-1) | HSV | Cold sore(s) | Herpes Labialis
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8. Full Text Upregulated CCL28 expression in the nasal mucosa in experimental allergic rhinitis: Implication for CD4+ memory T cell recruitment
by Nagakubo, Daisuke and Yoshie, Osamu and Hirata, Takako
Cellular Immunology, ISSN 0008-8749, 04/2016, Volume 302, pp. 58 - 62
During nasal immune responses, lymphocytes activated in the nasopharynx-associated lymphoid tissue (NALT) are thought to traffic to the nasal mucosa. Here we... 
Lymphocyte trafficking | T cells | Allergic rhinitis | Chemokines | Chemokine receptors | NALT | LYMPHOID-TISSUES | CC-CHEMOKINE | AIRWAY INFLAMMATION | RECEPTOR | IMMUNOLOGY | IDENTIFICATION | CELL BIOLOGY | MURINE MODEL | IMMUNE-SYSTEM | EPITHELIAL-CELLS | SECRETING CELLS | CCR10 | CD4-Positive T-Lymphocytes - immunology | Up-Regulation | Animals | Nasal Mucosa - immunology | Receptors, Chemokine - metabolism | Chemokines, CC - genetics | Immunologic Memory | Mice | Rhinitis, Allergic - physiopathology | Receptors, Chemokine - genetics | Chemokines, CC - metabolism | Disease Models, Animal
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9. Full Text Toxicological evaluation of a bioadhesive nasal powder containing a starch and Carbopol ® 974 P on rabbit nasal mucosa and slug mucosa
by Callens, C and Adriaens, E and Dierckens, K and Remon, J.P
Journal of Controlled Release, ISSN 0168-3659, 2001, Volume 76, Issue 1, pp. 81 - 91
The purpose of this study is the investigation of possible adverse effects of a powder formulation containing drum-dried waxy maize (DDWM) starch and Carbopol®... 
Nasal and mucosal toxicity | Rabbits | Carbopol ® 974 P | Slugs | Starch | Carbopol® 974 P | ABSORPTION ENHANCERS | Carbopol (R) 974 P | RAT | MICONAZOLE | VIVO | APPLICATION SITE | rabbits | FORMULATION | CHEMISTRY, MULTIDISCIPLINARY | nasal and mucosal toxicity | slugs | DELIVERY | IN-VITRO | PHARMACOLOGY & PHARMACY | starch | SLOW-RELEASE TABLET | BENZALKONIUM CHLORIDE | L-Lactate Dehydrogenase - secretion | Starch - administration & dosage | Powders | Animals | Mucous Membrane - drug effects | Nasal Mucosa - pathology | Acrylates - toxicity | Administration, Intranasal | Starch - toxicity | Acrylates - administration & dosage | Nasal Mucosa - drug effects
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10. Full Text Ex vivo permeation characteristics of venlafaxine through sheep nasal mucosa
by Pund, Swati and Rasve, Ganesh and Borade, Ganesh
European Journal of Pharmaceutical Sciences, ISSN 0928-0987, 01/2013, Volume 48, Issue 1-2, pp. 195 - 201
Venlafaxine, a dual acting antidepressant is a new therapeutic option for chronic depression. Depression is a common mental disorder associated with the... 
Ex vivo permeation | Venlafaxine | In situ gel | IN-VITRO | ANTIDEPRESSANTS | TRANSPORT | PHARMACOLOGY & PHARMACY | RELEASE | DRUG-DELIVERY SYSTEMS | BIOAVAILABILITY | GEL | Venlafaxine Hydrochloride | Animals | Adhesiveness | Sheep | Nasal Mucosa - metabolism | Antidepressive Agents, Second-Generation - administration & dosage | Nasal Mucosa - anatomy & histology | Permeability | In Vitro Techniques | Nasal Mucosa - drug effects | Cyclohexanols - administration & dosage
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11. Full Text Antigens Drive Memory IgE Responses in Human Allergy via the Nasal Mucosa
by Niederberger, Verena and Ring, Johannes and Rakoski, Jürgen and Jäger, Siegfried and Spitzauer, Susanne and Valent, Peter and Horak, Friedrich and Kundi, Michael and Valenta, Rudolf
International Archives of Allergy and Immunology, ISSN 1018-2438, 01/2007, Volume 142, Issue 2, pp. 133 - 144
Background: Natural allergen contact induces an increase of IgE levels and sensitivity but the mechanisms underlying the allergen-specific memory responses are... 
Original Paper | Recombinant allergen | Allergy | Nasal provocation | Nasal mucosa | IgE memory | ANTIBODIES | nasal provocation | FC-EPSILON-RI | IMMUNOLOGICAL MEMORY | POLLEN ALLERGENS | BONE-MARROW | allergy | SERUM | IMMUNOLOGY | B-CELLS | recombinant allergen | GERMLINE GENE TRANSCRIPTS | LIVED PLASMA-CELLS | HUMORAL IMMUNITY | nasal mucosa | Skin Tests | Immunoglobulin G - blood | Humans | Middle Aged | Hypersensitivity - immunology | Male | Administration, Intranasal | Immunoglobulin E - blood | Rhinitis, Allergic, Seasonal - immunology | Antigens - administration & dosage | Lymphocyte Activation - immunology | Immunoglobulin M - blood | Nasal Mucosa - immunology | Adult | Antigens - immunology | Female | Immunologic Memory | Administration, Topical | Hypersensitivity - blood | Skin - immunology | Antigens | Immunology | Nose | Allergies
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12. Full Text Effects of montelukast on human nasal mucosa
by Wang, Hsing-Won and Lee, Jih-Chin and Wu, Pei-Chuan and Chu, Yueng-Hsiang and Lin, Yuan-Yung and Cheng, Li-Hsiang
European Archives of Oto-Rhino-Laryngology, ISSN 0937-4477, 3/2019, Volume 276, Issue 3, pp. 761 - 765
Montelukast is a selective and orally active leukotriene D4 receptor antagonist often used in treating asthma and allergic rhinitis. Montelukast nasal spray... 
Medicine & Public Health | Head and Neck Surgery | Montelukast | Otorhinolaryngology | Neurosurgery | Human nasal mucosa | Sympathetic function | ASTHMA | OTORHINOLARYNGOLOGY | Yuan (China) | Respiratory agents | Electric fields | Analysis
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