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Molecular Medicine Reports, ISSN 1791-2997, 01/2016, Volume 13, Issue 1, pp. 853 - 859
Several studies have suggested that the balance of T helper 17 (Th17) and natural regulatory T (nTreg) cells in the Th17-mediated immune response are critical... 
Hepatitis | T helper 17/natural regulatory T cell imbalance | T helper 17 | Hepatitis B virus | Natural regulatory T cell | MEDICINE, RESEARCH & EXPERIMENTAL | TGF-BETA | DENDRITIC CELLS | natural regulatory T cell | hepatitis B virus | DISTINCT | hepatitis | INTERLEUKIN-17 PRODUCTION | PATHOGENESIS | ONCOLOGY | VIRUS INFECTION | T(H)17 | REGULATORY T-CELLS | DIFFERENTIATION | EXPRESSION
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 08/2017, Volume 23, Issue 15, pp. 4290 - 4300
Purpose: We study CD38 levels in immunosuppressive CD4(+)CD25(high)Foxp3(+) regulatory T cells (Treg) and further define immunomodulating effects of a... 
IN-VITRO | MICROENVIRONMENT | ONCOLOGY | IMMUNOTHERAPY | LENALIDOMIDE | DARATUMUMAB MONOTHERAPY | PERIPHERAL-BLOOD | PROLIFERATION | ANTITUMOR-ACTIVITY | CARCINOMA | CANCER | Leukocytes, Mononuclear - drug effects | Immunosuppression - methods | Cell Count | Humans | Interleukin-10 - blood | Multiple Myeloma - immunology | Immunologic Memory - drug effects | Transforming Growth Factor beta - blood | ADP-ribosyl Cyclase 1 - blood | T-Lymphocytes, Regulatory - immunology | Multiple Myeloma - drug therapy | Multiple Myeloma - pathology | T-Lymphocytes, Regulatory - drug effects | Antibodies, Monoclonal - administration & dosage | Immunosuppressive Agents - immunology | ADP-ribosyl Cyclase 1 - immunology | Cell Line, Tumor | Female | Gene Expression Regulation, Neoplastic - drug effects | Immunosuppressive Agents - administration & dosage | Immune Tolerance - drug effects | Multiple Myeloma - blood | Plasma | CD8 antigen | Multiple myeloma | Bone marrow transplantation | Recovery of function | Leukocytes (mononuclear) | Lymphocytes T | Immunosuppressive agents | Killer cells | Lymphocytes | CD38 antigen | Interleukin 1 | Bone marrow | Peripheral blood mononuclear cells | CD25 antigen | Foxp3 protein | Inhibition | Natural killer cells | Immunoregulation | Patients | CD4 antigen | Immunosuppression | Experimental design | Interleukin 10 | Lysis | Monoclonal antibodies | Health risk assessment | Cancer | IFNγ | CD107a | bone marrow stromal cells (BMSCs) | natural occurring Tregs (nTregs) | regulatory T (Treg) | CD38 | Isatuximab (Isa) (SAR650984) | PD1 | multiple myeloma (MM) | conventional T (Tcon) | tumor-induced Treg (iTregs)
Journal Article
Journal of Autoimmunity, ISSN 0896-8411, 2011, Volume 38, Issue 1, pp. 59 - 69
Abstract The Bcl-2 regulated apoptosis pathway is critical for the elimination of autoreactive lymphocytes, thereby precluding autoimmunity. T cells escaping... 
Allergy and Immunology | Bcl-2 | Autoimmunity | Regulatory T cells | Bim | Apoptosis | ACTIVATION | IMMUNOLOGY | SUPPRESSION | RESPONSES | CD4(+)CD25(+) | FOXP3(+) | EXPRESSION | T-CELLS | BH3-ONLY PROTEINS | TRANSGENIC MICE | T-Lymphocytes, Regulatory - metabolism | Cell Survival - genetics | Apoptosis - genetics | Male | Gene Expression Profiling | Green Fluorescent Proteins - genetics | Inflammatory Bowel Diseases - metabolism | Proto-Oncogene Proteins c-bcl-2 - metabolism | Flow Cytometry | Bcl-2-Like Protein 11 | Forkhead Transcription Factors - metabolism | Inflammatory Bowel Diseases - genetics | Apoptosis Regulatory Proteins - genetics | Female | Antineoplastic Agents - pharmacology | Membrane Proteins - metabolism | Thymus Gland - metabolism | Proto-Oncogene Proteins - metabolism | Cell Survival - drug effects | Green Fluorescent Proteins - metabolism | Membrane Proteins - genetics | Mice, Inbred C57BL | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Thymus Gland - cytology | Etoposide - pharmacology | Mice, Transgenic | Proto-Oncogene Proteins - genetics | Signal Transduction - genetics | Forkhead Transcription Factors - genetics | Reverse Transcriptase Polymerase Chain Reaction | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Animals | Mice | Proto-Oncogene Proteins c-bcl-2 - genetics | Antigens | Medical colleges | Genes | Fluorescence | Biochemistry | Biological response modifiers | Transforming growth factors | T cells | Analysis | Medical genetics | Physiological aspects | Lymphomas | Interferon gamma | Bcl-2L1, 1Bcl-2 interacting mediator of cell death | nTreg, natural regulatory T cells | GFP, green fluorescent protein | TGF-β, transforming growth factor beta | GITR, glucocorticoid-induced TNFR-related protein | CTLA-4, cytotoxic T lymphocyte antigen 4 | BH, Bcl-2 homology | Tcon, conventional CD4+ T cells | Bcl-2, B cell lymphoma 2 | IFN-γ, interferon gamma | iTreg, induced regulatory T cells | Foxp3, Forkhead box P3 | IL, interleukin | MFI, mean fluorescence intensity | TCR, T cell receptor
Journal Article
European Journal of Immunology, ISSN 0014-2980, 12/2011, Volume 41, Issue 12, pp. 3564 - 3573
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2011, Volume 108, Issue 47, pp. 18995 - 19000
Journal Article