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Journal Article
by Wang, XF and Sun, R and Hao, XL and Lian, ZX and Wei, HM and Tian, ZG
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 08/2019, Volume 116, Issue 35, pp. 17409 - 17418
Journal Article
Gastroenterology, ISSN 0016-5085, 2017, Volume 153, Issue 4, pp. 980 - 987
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 08/2014, Volume 20, Issue 15, pp. 4096 - 4106
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 09/2018, Volume 503, Issue 4, pp. 2807 - 2813
The regulation of natural killer (NK) cell activity is an important research goal for the development of immunotherapies. In this study, we identified... 
Transforming growth factor-beta | Interleukin-2 | Natural killer cells | c-Myb | Celastrol | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | CANCER | AUTOREGULATION | GROWTH-FACTOR-BETA | BIOPHYSICS | GENE | IMMUNOTHERAPY | INHIBITOR | EXPRESSION | RNA, Small Interfering - genetics | Triterpenes - pharmacology | Humans | Proto-Oncogene Proteins c-myb - antagonists & inhibitors | NK Cell Lectin-Like Receptor Subfamily K - immunology | Proto-Oncogene Proteins c-myb - genetics | Intracellular Signaling Peptides and Proteins - immunology | Granzymes - genetics | Killer Cells, Natural - immunology | Granzymes - immunology | Interferon-gamma - genetics | Cytotoxicity, Immunologic - drug effects | Intracellular Signaling Peptides and Proteins - genetics | Cell Line | Signal Transduction | Gene Expression Regulation | Protein-Serine-Threonine Kinases - genetics | Proto-Oncogene Proteins c-myc - immunology | Proto-Oncogene Proteins c-myb - immunology | NK Cell Lectin-Like Receptor Subfamily K - genetics | Killer Cells, Natural - cytology | Transforming Growth Factor beta - pharmacology | Lymphocyte Activation - drug effects | Interferon-gamma - immunology | Interleukin-2 - pharmacology | Protein-Serine-Threonine Kinases - immunology | Cell Proliferation - drug effects | Killer Cells, Natural - drug effects | Proto-Oncogene Proteins c-myc - genetics | Primary Cell Culture | Immunologic Factors - pharmacology | RNA, Small Interfering - metabolism | Virus diseases | Medical colleges | Killer cells | Interleukins | Microbiology | Immunotherapy | Bone morphogenetic proteins | DNA binding proteins | Transforming growth factors
Journal Article
03/2011
Aim: To evaluate natural killer (NK) cells activity in breast cancer patients and its comparison with normal individuals. Settings and Design: Breast cancer is... 
flowcytometry | natural killer- Cell | mastectomy | Breast cancer
Web Resource
PLoS ONE, ISSN 1932-6203, 04/2017, Volume 12, Issue 4, p. e0175793
Hepatitis C virus (HCV) infection is characterized by a high frequency of chronic cases owing to the impairment of innate and adaptive immune responses. The... 
INHIBITORY RECEPTOR GENES | NK CELLS | MULTIDISCIPLINARY SCIENCES | INNATE | INFECTION | ADAPTIVE IMMUNE-RESPONSES | CYTOTOXICITY | EXPRESSION | CANCER | T-CELLS | NKP30 | Macrocyclic Compounds - chemistry | Interleukin-12 - genetics | Coculture Techniques | Humans | Natural Cytotoxicity Triggering Receptor 3 - metabolism | Interferon-gamma - metabolism | Natural Cytotoxicity Triggering Receptor 3 - genetics | Recombinant Proteins - biosynthesis | Carbamates - chemistry | Quinolines - pharmacology | Macrocyclic Compounds - pharmacology | Recombinant Proteins - isolation & purification | Hepatitis C - immunology | Serine Proteinase Inhibitors - chemistry | Natural Cytotoxicity Triggering Receptor 1 - genetics | Killer Cells, Natural - immunology | Serine Proteinase Inhibitors - pharmacology | Carbamates - pharmacology | Interleukin-12 - pharmacology | Cell Line | Cell Survival - drug effects | Quinolines - chemistry | Viral Nonstructural Proteins - genetics | Interleukin-12 - metabolism | Recombinant Proteins - pharmacology | Down-Regulation - drug effects | Microscopy, Confocal | Hepacivirus - enzymology | Interferon-gamma - analysis | Hepatitis C - virology | K562 Cells | Natural Cytotoxicity Triggering Receptor 1 - metabolism | Thiazoles - chemistry | Viral Nonstructural Proteins - metabolism | Killer Cells, Natural - drug effects | Thiazoles - pharmacology | Hepatitis C - pathology | Killer Cells, Natural - metabolism | Viral Nonstructural Proteins - antagonists & inhibitors | Physiological aspects | Killer cells | Genetic aspects | Research | Hepatitis C virus | Proteases | Cell culture | Flow cytometry | Target recognition | Serine | Science | Chronic infection | Cytotoxicity | Viruses | Infections | Negative selection | Proteins | Hepatitis | Immunology | Gastroenterology | Penicillin | Tumor necrosis factor-TNF | Natural killer cells | Enzyme-linked immunosorbent assay | Deoxyribonucleic acid--DNA | Immune response | Cytokines | T cell receptors | Virology | Medicine | Brain research | Degranulation | Ligands | Serine proteinase | Interferon | Nonstructural proteins | Hepatitis C | Viral infections | Deoxyribonucleic acid | DNA
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2016, Volume 11, Issue 2, p. e0148764
VTX-2337 (USAN: motolimod) is a selective toll-like receptor 8 (TLR8) agonist, which is in clinical development as an immunotherapy for multiple oncology... 
HEAD | ENHANCE | NK CELLS | CANCER CELLS | IMMUNE-RESPONSES | MULTIDISCIPLINARY SCIENCES | CRYSTALS | GENERATION | TUMORS | CD8(+) T-CELLS | NALP3 INFLAMMASOME | Neoplasms - metabolism | Leukocytes, Mononuclear - metabolism | Inflammasomes - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | Macaca fascicularis | Caspase 1 - metabolism | Male | Receptors, IgG - metabolism | Carrier Proteins - agonists | Lymphocyte Activation - immunology | Neoplasms - genetics | Leukocytes, Mononuclear - immunology | Killer Cells, Natural - immunology | Female | Interleukin-1beta - biosynthesis | Disease Models, Animal | Toll-Like Receptor 8 - agonists | Leukocytes, Mononuclear - drug effects | Benzazepines - pharmacology | Cell Degranulation - immunology | Interleukin-18 - biosynthesis | Animals | Benzazepines - therapeutic use | Lymphocyte Activation - drug effects | Neoplasms - immunology | K562 Cells | Cell Line, Tumor | Killer Cells, Natural - drug effects | Killer Cells, Natural - metabolism | Cytotoxicity, Immunologic - immunology | Cell Degranulation - drug effects | Physiological aspects | Toll-like receptors | Killer cells | Genetic aspects | Research | Immunotherapy | Toxicity | Cytotoxicity | Stimulation | Activation | Lymphocytes T | Monkeys | Cancer therapies | Caspase-1 | Metastases | NKG2 antigen | Cell activation | Epidermal growth factor | Lymphocytes | Rodents | Biocompatibility | Neck | Natural killer cells | Antibody-dependent cell-mediated cytotoxicity | Squamous cell carcinoma | Cytokines | Dendritic cells | Tumor cells | Caspase | T cell receptors | Tumor necrosis factor-α | Patients | Interleukin 18 | Medicine | Monocytes | Complement activation | Pyrin protein | Womens health | γ-Interferon | Monoclonal antibodies | Ligands | Lymphomas | Pharmaceuticals
Journal Article
European Journal of Neuroscience, ISSN 0953-816X, 09/2004, Volume 20, Issue 5, pp. 1341 - 1347
Journal Article