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Journal Article
Acta dermato-venereologica, ISSN 0001-5555, 2014, Volume 94, Issue 6, pp. 640 - 644
Dermal exposure to alkaline agents may lead to skin barrier damage and irritant contact dermatitis. The objective of this study was to investigate the effects... 
Filaggrin mutations | Natural moisturising factor | Transepidermal water loss | Alkaline agents | Atopic dermatitis | Irritant contact dermatitis | POPULATION | transepidermal water loss | filaggrin mutations | natural moisturising factor | ECZEMA | QUANTIFICATION | irritant contact dermatitis | STRATUM-CORNEUM | atopic dermatitis | PENETRATION | DERMATOLOGY | alkaline agents | SODIUM LAURYL SULFATE | IN-VIVO | IRRITANT CONTACT-DERMATITIS | UNINVOLVED SKIN | Dermatitis, Atopic - genetics | Skin Irritancy Tests | Skin - metabolism | Water Loss, Insensible - drug effects | Humans | Middle Aged | Male | Administration, Cutaneous | Case-Control Studies | Dermatitis, Atopic - diagnosis | Erythema - chemically induced | Young Adult | Sodium Hydroxide - adverse effects | Time Factors | Erythema - diagnosis | Intermediate Filament Proteins - genetics | Adult | Female | Dermatitis, Irritant - metabolism | Skin - pathology | Sodium Dodecyl Sulfate - administration & dosage | Sodium Hydroxide - administration & dosage | Genetic Predisposition to Disease | Dermatitis, Irritant - diagnosis | Risk Factors | Water - metabolism | Irritants - adverse effects | Sodium Dodecyl Sulfate - adverse effects | Dermatitis, Atopic - complications | Irritants - administration & dosage | Phenotype | Dermatitis, Irritant - etiology | Aged | Mutation | Dermatitis, Atopic - metabolism | Skin - drug effects | Hydrogen-Ion Concentration | Index Medicus
Journal Article
Journal Article
Analytical Letters, ISSN 0003-2719, 09/2013, Volume 46, Issue 14, pp. 2133 - 2144
The levels of natural moisturizing factors in the skin can be used as a biomarker of hydration, for studying the effect of skin irritants, or as a biomarker of... 
Natural moisturizing factors | Ammonia | Stratum corneum | Filaggrin | Tape strip | HPLC | FILAGGRIN GENOTYPE | CHEMISTRY, ANALYTICAL | QUANTIFICATION | UROCANIC ACID | IN-VITRO | SKIN | INFRARED DENSITOMETRY | Proteins | Mutations | Solvents | Genes | Extraction | Chromatography | Optical density
Journal Article
Applied Spectroscopy, ISSN 0003-7028, 1/2012, Volume 66, Issue 1, pp. 26 - 32
Water-soluble components in the outermost layer of human skin are called natural moisturizing factor (NMF). NMF is one of the most important factors of skin... 
SC | Infrared spectroscopy | Noninvasive measurements | Stratum corneum | NMF | Attenuated total reflection | Skin | Natural moisturizing factor | ATR | In vivo measurements | ACID CONTENT | MOLECULAR-LEVEL | HYDRATION | INSTRUMENTS & INSTRUMENTATION | SPECTROSCOPY | EPIDERMIS | XEROSIS | WATER | AGE
Journal Article
Clinical, cosmetic and investigational dermatology, ISSN 1178-7015, 2018, Volume 11, pp. 491 - 497
Moisturizers are topical products designed to improve and maintain the skin barrier function and to help prevent dry skin. A new moisturizer (Ceramide cream)... 
Allergy | Skin | Testing | moisturizer | stratum corneum | ceramide | transepidermal water loss | hydration | natural moisturizing factor
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2012, Volume 129, Issue 4, pp. 1031 - 1039.e1
Background Filaggrin (FLG) mutations result in reduced stratum corneum (SC) natural moisturizing factor (NMF) components and consequent increased SC pH.... 
Allergy and Immunology | skin barrier | transepidermal water loss | confocal Raman spectroscopy | Flgft/Flgft (FlgdelAPfal) mice | Atopic dermatitis | IL-1 | IL-18 | FLG gene mutations | eczema | filaggrin | natural moisturizing factor | pH | UNCONVENTIONAL PROTEIN SECRETION | INTERLEUKIN-1 RECEPTOR ANTAGONIST | TERM CULTURE | IMMUNOLOGY | PERMEABILITY BARRIER HOMEOSTASIS | HUMAN KERATINOCYTES | IN-VITRO | ALLERGY | Flg(ft)/Flg(ft)(Flg(delAPfal)) mice | EPIDERMIS | IL-1-BETA | Interleukin-1 - genetics | Interleukin-1 - metabolism | Dermatitis, Atopic - genetics | Cytokines - metabolism | Skin - metabolism | Humans | Mice, Inbred C57BL | Child, Preschool | Genotype | Infant | Male | Mice, Knockout | Animals | Adolescent | Alleles | Intermediate Filament Proteins - genetics | Female | Mice | Mutation | Child | Dermatitis, Atopic - metabolism | Intermediate Filament Proteins - metabolism | Hydrogen-Ion Concentration | Medical colleges | Cytokines | Proteases | Genes | Respiratory agents | Genetic aspects | Skin | Inflammation | Universities and colleges | Dermatitis | Proteins | Enzymes | Genotype & phenotype | Hypotheses | Families & family life | Values | Homeostasis | Animal models | Stratum corneum | Interleukin 1 receptor antagonist | Proteinase | Keratinocytes | mRNA | Filaggrin | Raman spectroscopy | pH effects | Tails | Interleukin 18 | Polymerase chain reaction | Water loss | Primers | Interleukin 1 | Interleukin 8 | Index Medicus | Abridged Index Medicus | FLG | SC, Stratum corneum | Flgft | Patient homozygous for null alleles (ie, 2 null alleles) | AD, Atopic dermatitis | FLG, Filaggrin gene | Homozygote wild-type (ie, 0 null alleles) | TEWL, Transepidermal water loss | Heterozygote null allele | Flgft (FlgdelAPfal) mice | IL-1RA, IL-1 receptor antagonist | wild-type (ie, 1 null allele) | NMF, Natural moisturizing factor | ADFLG, AD with FLG mutations | Atopic Dermatitis and Skin Disease | NESS, Nottingham Eczema Severity Score | ADNON-FLG, AD without FLG mutations
Journal Article