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PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 8, p. e21225
Background: The safety and immunogenicity of a vaccine regimen consisting of a 6-plasmid HIV-1 DNA prime (envA, envB, envC, gagB, polB, nefB) boosted by a... 
RESPONSES | IMMUNITY | ASSAY | SAFETY | MULTIDISCIPLINARY SCIENCES | ANTIBODY | IMMUNOGENICITY EVALUATION | CANDIDATE | INFECTION | STEP | MEMORY T-CELLS | env Gene Products, Human Immunodeficiency Virus - immunology | Immunization, Secondary - adverse effects | Immunoglobulin G - blood | Human Immunodeficiency Virus Proteins - immunology | Humans | Middle Aged | AIDS Vaccines - immunology | Vaccines, DNA - immunology | pol Gene Products, Human Immunodeficiency Virus - immunology | Male | Antibodies, Viral - blood | Vaccines, DNA - administration & dosage | Young Adult | env Gene Products, Human Immunodeficiency Virus - genetics | T-Lymphocytes - metabolism | Immunoglobulin G - immunology | Adenoviridae - genetics | Adult | Female | gag Gene Products, Human Immunodeficiency Virus - genetics | pol Gene Products, Human Immunodeficiency Virus - genetics | Immunization - adverse effects | Enzyme-Linked Immunosorbent Assay | Immunization - methods | Anemia - chemically induced | Immunization, Secondary - methods | HIV-1 - genetics | HIV-1 - immunology | nef Gene Products, Human Immunodeficiency Virus - genetics | nef Gene Products, Human Immunodeficiency Virus - immunology | Interferon-gamma - immunology | Adolescent | Antibodies, Viral - immunology | Human Immunodeficiency Virus Proteins - genetics | T-Lymphocytes - immunology | AIDS Vaccines - administration & dosage | gag Gene Products, Human Immunodeficiency Virus - immunology | Interferon-gamma - blood | Cohort Studies | Oligomers | AIDS vaccines | Adenoviruses | Immunotherapy | DNA | Clinical trials | Product development | Interferon | Biological response modifiers | T cells | HIV (Viruses) | Antigenic determinants | Health care | CD8 antigen | Antibodies | Lymphocytes T | Infections | Vaccines | Epidemiology | Randomization | Acquired immune deficiency syndrome--AIDS | Human immunodeficiency virus--HIV | Inserts | Deoxyribonucleic acid--DNA | Enzyme-linked immunosorbent assay | Recombinant | Binding | Medical research | Immunoglobulins | Cytokines | Epitopes | Immune response (humoral) | CD4 antigen | Disease prevention | Hospitals | Infectious diseases | Immunogenicity | γ-Interferon | Adults | Cancer | Acquired immune deficiency syndrome | Deoxyribonucleic acid | AIDS | HIV | Human immunodeficiency virus
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 1371 - 16
HIV-1 causes chronic inflammation and AIDS in humans, whereas related simian immunodeficiency viruses (SIVs) replicate efficiently in their natural hosts... 
SIMIAN-IMMUNODEFICIENCY-VIRUS | MULTIDISCIPLINARY SCIENCES | INFECTED SOOTY MANGABEYS | T-CELL-ACTIVATION | IN-VIVO | AFRICAN-GREEN MONKEYS | CD4 DOWN-REGULATION | HIV-1 VPU INTERFERENCE | NF-KAPPA-B | SIV INFECTION | LYMPHOCYTE-ACTIVATION | Bone Marrow Stromal Antigen 2 - genetics | HIV-1 - pathogenicity | Human Immunodeficiency Virus Proteins - immunology | Humans | Virulence | NF-kappa B - immunology | Cercopithecus aethiops | Simian Immunodeficiency Virus - growth & development | Viral Load | CD3 Complex - genetics | HIV-1 - growth & development | Female | Transcription, Genetic | Bone Marrow Stromal Antigen 2 - immunology | Amino Acid Sequence | Simian Immunodeficiency Virus - pathogenicity | Signal Transduction | Lentiviruses, Primate - growth & development | Lymphocyte Activation | Viral Regulatory and Accessory Proteins - immunology | Viral Regulatory and Accessory Proteins - genetics | Gene Expression Regulation | Host Specificity | Sequence Alignment | Animals | NF-kappa B - genetics | Virus Replication | nef Gene Products, Human Immunodeficiency Virus - genetics | nef Gene Products, Human Immunodeficiency Virus - immunology | CD3 Complex - immunology | Human Immunodeficiency Virus Proteins - genetics | Lentiviruses, Primate - pathogenicity | Pathogens | NF-κB protein | Viremia | Immunodeficiency | Vpu protein | Viruses | Activation | Monkeys | Lymphocytes T | CD3 antigen | Pathogenicity | Cell activation | Nef protein | Acquired immune deficiency syndrome--AIDS | Virulence factors | Transcription activation | Human immunodeficiency virus--HIV | HIV-1 | Viral Regulatory and Accessory Proteins | Life Sciences | NF-kappa B | Immunology | CD3 Complex | Human Immunodeficiency Virus Proteins | Animal biology | Virology | Human health and pathology | Microbiology and Parasitology | Infectious diseases | Lentiviruses, Primate | Bone Marrow Stromal Antigen 2 | Simian Immunodeficiency Virus | nef Gene Products, Human Immunodeficiency Virus
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 7/2009, Volume 186, Issue 2, pp. 255 - 268
Autophagy is a cytoplasmic degradative pathway that can participate in biosynthetic processes, as in the yeast Cvt pathway, but is more commonly known for its... 
T lymphocytes | HIV | Virions | Antibodies | Viruses | AIDS | Cell membranes | Macrophages | Organelles | HIV 1 | MYCOBACTERIUM-TUBERCULOSIS | ADAPTIVE IMMUNITY | TYPE-1 NEF | NEF PROTEIN | PHOSPHATIDYLINOSITOL 3-KINASE | TRAFFICKING | INFECTION | HUMAN-IMMUNODEFICIENCY-VIRUS | PLASMA-MEMBRANE | CELL | CELL BIOLOGY | RNA, Small Interfering - genetics | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Humans | Autophagy - physiology | Recombinant Fusion Proteins - metabolism | gag Gene Products, Human Immunodeficiency Virus - metabolism | HIV-1 - physiology | Macrophages - virology | Apoptosis Regulatory Proteins - genetics | nef Gene Products, Human Immunodeficiency Virus - metabolism | Membrane Proteins - metabolism | gag Gene Products, Human Immunodeficiency Virus - genetics | Beclin-1 | Biomarkers - metabolism | Cell Line | Macrophages - ultrastructure | Ubiquitin-Activating Enzymes - genetics | Membrane Proteins - genetics | Ubiquitin-Activating Enzymes - metabolism | Apoptosis Regulatory Proteins - metabolism | Autophagy-Related Protein 7 | Animals | nef Gene Products, Human Immunodeficiency Virus - genetics | Recombinant Fusion Proteins - genetics | Virus Replication - physiology | RNA, Small Interfering - metabolism | Virus diseases | Physiological aspects | HIV (Viruses)
Journal Article
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 8, p. e23293
HIV proteins target host hub proteins for transient binding interactions. The presence of viral proteins in the infected cell results in out-competition of... 
REPLICATION | PHOSPHORYLATION | TAT | MULTIDISCIPLINARY SCIENCES | KINASE | IMMUNODEFICIENCY-VIRUS TYPE-1 | SH3 DOMAINS | SHORT LINEAR MOTIFS | BINDING | VIRAL-INFECTION | NEF | rev Gene Products, Human Immunodeficiency Virus - chemistry | Humans | env Gene Products, Human Immunodeficiency Virus - metabolism | rev Gene Products, Human Immunodeficiency Virus - metabolism | nef Gene Products, Human Immunodeficiency Virus - chemistry | tat Gene Products, Human Immunodeficiency Virus - chemistry | CREB-Binding Protein - metabolism | gag Gene Products, Human Immunodeficiency Virus - metabolism | env Gene Products, Human Immunodeficiency Virus - genetics | Human Immunodeficiency Virus Proteins - chemistry | Databases, Protein | nef Gene Products, Human Immunodeficiency Virus - metabolism | gag Gene Products, Human Immunodeficiency Virus - genetics | env Gene Products, Human Immunodeficiency Virus - chemistry | Protein Structure, Tertiary | Amino Acid Sequence | Calmodulin - metabolism | Protein Structure, Secondary | tat Gene Products, Human Immunodeficiency Virus - genetics | Models, Molecular | gag Gene Products, Human Immunodeficiency Virus - chemistry | Binding Sites - genetics | Human Immunodeficiency Virus Proteins - metabolism | Proteins - genetics | Protein Interaction Mapping - methods | Proteins - metabolism | nef Gene Products, Human Immunodeficiency Virus - genetics | Hydrophobic and Hydrophilic Interactions | Protein Binding | Human Immunodeficiency Virus Proteins - genetics | rev Gene Products, Human Immunodeficiency Virus - genetics | Amino Acid Motifs - genetics | Calcium-Calmodulin-Dependent Protein Kinases - metabolism | Casein Kinase II - metabolism | Mitogen-Activated Protein Kinase 1 - metabolism | tat Gene Products, Human Immunodeficiency Virus - metabolism | Physiological aspects | Viral proteins | HIV (Viruses) | Genomics | Protein binding | Phenotypes | Phosphorylation | Hot spots | Crosstalk | Amino acid sequence | Viruses | Genomes | Kinases | Proteins | Conserved sequence | Human immunodeficiency virus--HIV | Computer applications | Mutation | Localization | Bioinformatics | Binding sites | HIV | Human immunodeficiency virus
Journal Article
Virology, ISSN 0042-6822, 10/2018, Volume 523, pp. 121 - 128
The HIV-1 accessory protein Vpr displays various activities that can favor viral replication such as G cell cycle arrest. Vpr also modulates host gene... 
HIV-1 | CD62L | Vpr | DDR | Nef | ATR | TRANSCRIPTION FACTORS | PROTEIN VPR | ACTIVATION | DNA-DAMAGE RESPONSE | NKG2D RECEPTOR | HUMAN-IMMUNODEFICIENCY-VIRUS | CLASS-I HDACS | VIROLOGY | LIGANDS | TYPE-1 | T-CELLS | Ataxia Telangiectasia Mutated Proteins - metabolism | Humans | L-Selectin - genetics | vif Gene Products, Human Immunodeficiency Virus - genetics | RNA, Messenger - metabolism | L-Selectin - metabolism | vif Gene Products, Human Immunodeficiency Virus - metabolism | nef Gene Products, Human Immunodeficiency Virus - metabolism | CD4-Positive T-Lymphocytes - virology | vpr Gene Products, Human Immunodeficiency Virus - metabolism | HIV-1 - metabolism | Signal Transduction | Jurkat Cells | RNA, Messenger - genetics | Viral Regulatory and Accessory Proteins - genetics | CD4-Positive T-Lymphocytes - metabolism | Gene Expression Regulation | HIV-1 - genetics | Viral Regulatory and Accessory Proteins - metabolism | Host-Pathogen Interactions | Human Immunodeficiency Virus Proteins - metabolism | G2 Phase Cell Cycle Checkpoints - genetics | Histones - genetics | nef Gene Products, Human Immunodeficiency Virus - genetics | Human Immunodeficiency Virus Proteins - genetics | Histones - metabolism | Primary Cell Culture | Ataxia Telangiectasia Mutated Proteins - genetics | vpr Gene Products, Human Immunodeficiency Virus - genetics | RNA | T cells | HIV (Viruses) | Gene expression | Analysis
Journal Article
Journal of Virology, ISSN 0022-538X, 2015, Volume 89, Issue 10, pp. 5330 - 5339
Journal Article
Journal Article