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1. Full Text Treatment of gastric cancer
by Michele Orditura Gennaro Galizia Vincenzo Sforza Valentina Gambardella Alessio Fabozzi Maria Maddalena Laterza Francesca Andreozzi Jole Ventriglia Beatrice Savastano Andrea Mabilia Eva Lieto Fortunato Ciardiello Ferdinando De Vita
世界胃肠病学杂志：英文版（电子版）, ISSN 1007-9327, 2014, Volume 20, Issue 7, pp. 1635 - 1649
The authors focused on the current surgical treatment of resectable gastric cancer,and significance of periand post-operative chemo or chemoradiation.Gastric... 
chemo | Gastric | cancer | Adjuvant | Radiotherapy | Surgery | Adjuvant chemotherapy | Gastric cancer | Chemoradiation | Palliative chemotherapy | GASTROESOPHAGEAL ADENOCARCINOMA | CLINICAL-TRIAL | HIGH-DOSE METHOTREXATE | CURATIVE RESECTION | NEOADJUVANT CHEMOTHERAPY | RANDOMIZED PHASE-III | EUROPEAN-ORGANIZATION | HYPERTHERMIC INTRAPERITONEAL CHEMOTHERAPY | 1ST-LINE THERAPY | GASTROENTEROLOGY & HEPATOLOGY | Stomach Neoplasms - radiotherapy | Chemoradiotherapy - methods | Humans | Receptor, ErbB-2 - metabolism | Clinical Trials as Topic | Stomach Neoplasms - drug therapy | Cisplatin - administration & dosage | Neoplasm Metastasis | Antibodies, Monoclonal, Humanized - administration & dosage | Fluorouracil - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Chemotherapy, Adjuvant - methods | Radiotherapy - methods | Stomach Neoplasms - surgery | Trastuzumab | Palliative Care - methods | Topic Highlight
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2. Full Text Japanese gastric cancer treatment guidelines 2014 (ver. 4)
by Anon and Japanese Gastric Canc Assoc and Japanese Gastric Cancer Association
Gastric Cancer, ISSN 1436-3291, 1/2017, Volume 20, Issue 1, pp. 1 - 19
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1007/s10120-016-0622-4 
Medicine & Public Health | Endoscopic Resection | Gastroenterology | Abdominal Surgery | Gastric Cancer | Oncology | Cancer Research | Distal Gastrectomy | Surgical Oncology | Endoscopic Submucosal Dissection | Trastuzumab | LYMPH-NODE DISSECTION | ADJUVANT CHEMOTHERAPY | DISTAL GASTRECTOMY | NEOADJUVANT CHEMOTHERAPY | ONCOLOGY | RANDOMIZED PHASE-III | COMBINATION CHEMOTHERAPY | 2ND-LINE CHEMOTHERAPY | PERITONEAL METASTASIS | SURGICAL RESECTION | GASTROENTEROLOGY & HEPATOLOGY | S-1 PLUS CISPLATIN | Algorithms | Time Factors | Humans | Japan | Stomach Neoplasms - therapy | Combined Modality Therapy | Clinical Trials as Topic - standards | Stomach Neoplasms - drug therapy | Stomach Neoplasms - surgery | Practice guidelines (Medicine) | Care and treatment | Drug therapy | Stomach cancer | Cancer | Special
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3. Full Text Molecular alterations in triple-negative breast cancer—the road to new treatment strategies
by Denkert, Carsten, Dr and Liedtke, Cornelia, MD and Tutt, Andrew, MD and von Minckwitz, Gunter, MD
Lancet, The, ISSN 0140-6736, 2016, Volume 389, Issue 10087, pp. 2430 - 2442
Summary Triple-negative breast cancer is a heterogeneous disease and specific therapies have not been available for a long time. Therefore, conventional... 
Internal Medicine | TUMOR-INFILTRATING LYMPHOCYTES | BASAL-LIKE | MEDICINE, GENERAL & INTERNAL | ADENOID CYSTIC CARCINOMAS | NEOADJUVANT CHEMOTHERAPY | GENE-EXPRESSION | PHASE-II | SYNTHETIC LETHALITY | OPEN-LABEL | ADJUVANT BEVACIZUMAB | DOSE-DENSE DOXORUBICIN | Humans | Gene Expression Profiling - methods | Antineoplastic Agents - therapeutic use | Triple Negative Breast Neoplasms - drug therapy | Triple Negative Breast Neoplasms - immunology | Triple Negative Breast Neoplasms - genetics | Neoadjuvant Therapy - methods | Biomarkers, Tumor - metabolism | Female | Mutation | Genomics - methods | Ubiquitin-Protein Ligases - genetics | BRCA2 Protein - genetics | Molecular Targeted Therapy - methods | Lymphocytes, Tumor-Infiltrating - immunology | Medical research | Chemotherapy | RNA | Analysis | Stem cells | Medicine, Experimental | Breast cancer | Hormones, Sex | Angiogenesis inhibitors | Cancer | Androgens | Research institutes | Intervention | Therapy | State of the art | Mesenchyme | Androgen receptors | Homologous recombination | DNA damage | Medical services | Series (mathematics) | Clinical trials | Homology | Oncology | mRNA | Biology | Metastasis | Cancer therapies | Subgroups | Receptors | Alterations | Immunology | Signatures | Damage | Deoxyribonucleic acid--DNA | BRCA2 protein | BRCA1 protein | Markers | Gene expression | Biological activity | Inhibitors | Immune checkpoint | Breast | Tumors
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4. Full Text Magnetic resonance imaging as a predictor of pathologic response in patients treated with neoadjuvant systemic treatment for operable breast cancer: Translational Breast Cancer Research Consortium trial 017
by De Los Santos, Jennifer F and Cantor, Alan and Amos, Keith D and Forero, Andres and Golshan, Mehra and Horton, Janet K and Hudis, Clifford A and Hylton, Nola M and McGuire, Kandace and Meric-Bernstam, Funda and Meszoely, Ingrid M and Nanda, Rita and Hwang, E. Shelley
Cancer, ISSN 0008-543X, 05/2013, Volume 119, Issue 10, pp. 1776 - 1783
BACKGROUND: Increased pathologic complete response (pCR) rates observed with neoadjuvant chemotherapy (NCT) for some subsets of patients with invasive breast... 
neoadjuvant chemotherapy | accuracy | breast cancer | pathologic complete response | magnetic resonance imaging | TRASTUZUMAB | RANDOMIZED-TRIAL | CHEMOTHERAPY | MAMMOGRAPHY | WOMEN | RESIDUAL TUMOR EXTENT | CONTRALATERAL BREAST | ONCOLOGY | HIGH-RISK | MRI EVALUATION | Immunohistochemistry | Breast Neoplasms - surgery | Predictive Value of Tests | Carcinoma, Lobular - pathology | Humans | Middle Aged | Induction Chemotherapy | Receptors, Estrogen - analysis | Receptors, Progesterone - analysis | Breast Neoplasms - chemistry | Carcinoma, Ductal, Breast - drug therapy | Neoplasm Grading | Sensitivity and Specificity | Adult | Carcinoma, Ductal, Breast - pathology | Female | Retrospective Studies | Biomarkers, Tumor - analysis | Treatment Outcome | Breast Neoplasms - drug therapy | Magnetic Resonance Imaging | Analysis of Variance | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Breast Neoplasms - pathology | Neoadjuvant Therapy - methods | Aged | Carcinoma, Lobular - drug therapy | Receptor, ErbB-2 - analysis | Neoplasm Staging | Neoadjuvant therapy | Usage | Care and treatment | Breast cancer | Magnetic resonance imaging
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5. Full Text Evaluation of response after neoadjuvant treatment in soft tissue sarcomas; the European Organization for Research and Treatment of Cancer–Soft Tissue and Bone Sarcoma Group (EORTC–STBSG) recommendations for pathological examination and reporting
by Wardelmann, E and Haas, R.L and Bovée, J.V.M.G and Terrier, Ph and Lazar, A and Messiou, C and LePechoux, C and Hartmann, W and Collin, F and Fisher, C and Mechtersheimer, G and DeiTos, A.P and Stacchiotti, S and Jones, R.L and Gronchi, A and Bonvalot, S
European Journal of Cancer, ISSN 0959-8049, 2015, Volume 53, pp. 84 - 95
Abstract At present, there is not a commonly used and generally accepted standardized approach for the pathologic evaluation of pretreated soft tissue... 
Hematology, Oncology and Palliative Medicine | Soft tissue sarcoma | Pathology | Guideline | Chemotherapy | Radiotherapy | Response evaluation | HISTOLOGIC RESPONSE | EWINGS-SARCOMA | PLUS SORAFENIB | HIGH-RISK EXTREMITY | PREOPERATIVE HYPOFRACTIONATED RADIOTHERAPY | RADIATION-THERAPY | HIGH-GRADE | ONCOLOGY | PHASE-I TRIAL | HISTOPATHOLOGIC RESPONSE | PROGNOSTIC-SIGNIFICANCE | Immunohistochemistry | Microscopy - methods | Magnetic Resonance Imaging | Bone Neoplasms - radiotherapy | Humans | Neoadjuvant Therapy - methods | Bone Neoplasms - drug therapy | Sarcoma - drug therapy | Sarcoma - pathology | Bone Neoplasms - pathology | Sarcoma - radiotherapy | Task forces | Sarcoma | Analysis | Oncology, Experimental | Adjuvant treatment | Research | Drug therapy | Cancer
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6. Full Text Identification and use of biomarkers in treatment strategies for triple‐negative breast cancer subtypes
by Lehmann, Brian D and Pietenpol, Jennifer A
The Journal of Pathology, ISSN 0022-3417, 01/2014, Volume 232, Issue 2, pp. 142 - 150
Triple‐negative breast cancer (TNBC) is a heterogeneous disease with distinct molecular subtypes that respond differentially to chemotherapy and targeted... 
triple‐negative breast cancer | therapy | PTEN | FGFR | EGFR | subtypes | INPP4B | LDHB | WEE1 | PIK3CA | basal‐like | VEGFR | TNBCtype | PHGDH | genomic instability | TP53 | basal-like | triple-negative breast cancer | THERAPEUTIC STRATEGY | OVARIAN-CANCER | PATHOLOGY | TUMORS | LI-FRAUMENI-SYNDROME | MOLECULAR PORTRAITS | NEOADJUVANT CHEMOTHERAPY | MUTANT P53 | ONCOLOGY | RANDOMIZED PHASE-II | MONOCLONAL-ANTIBODIES | DNA-REPAIR | Genetic Predisposition to Disease | Biomarkers, Tumor - analysis | Humans | Antineoplastic Agents - therapeutic use | Molecular Targeted Therapy | Triple Negative Breast Neoplasms - drug therapy | Drug Discovery | Patient Selection | Phenotype | Triple Negative Breast Neoplasms - chemistry | Triple Negative Breast Neoplasms - classification | Animals | Triple Negative Breast Neoplasms - genetics | Signal Transduction - drug effects | Triple Negative Breast Neoplasms - pathology | Female | Biomarkers, Tumor - genetics | Precision Medicine | Breast cancer | Tumor proteins | Biological markers | Vascular endothelial growth factor | Triple negative breast cancer
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7. Full Text Adaptive Randomization of Veliparib–Carboplatin Treatment in Breast Cancer
by Rugo, Hope S and Olopade, Olufunmilayo I and DeMichele, Angela and Yau, Christina and van ’t Veer, Laura J and Buxton, Meredith B and Hogarth, Michael and Hylton, Nola M and Paoloni, Melissa and Perlmutter, Jane and Symmans, W. Fraser and Yee, Douglas and Chien, A. Jo and Wallace, Anne M and Kaplan, Henry G and Boughey, Judy C and Haddad, Tufia C and Albain, Kathy S and Liu, Minetta C and Isaacs, Claudine and Khan, Qamar J and Lang, Julie E and Viscusi, Rebecca K and Pusztai, Lajos and Moulder, Stacy L and Chui, Stephen Y and Kemmer, Kathleen A and Elias, Anthony D and Edmiston, Kirsten K and Euhus, David M and Haley, Barbara B and Nanda, Rita and Northfelt, Donald W and Tripathy, Debasish and Wood, William C and Ewing, Cheryl and Schwab, Richard and Lyandres, Julia and Davis, Sarah E and Hirst, Gillian L and Sanil, Ashish and Berry, Donald A and Esserman, Laura J and I-SPY 2 Investigators
The New England Journal of Medicine, ISSN 0028-4793, 07/2016, Volume 375, Issue 1, pp. 23 - 34
Using an adaptive trial design to minimize the exposure of patients to inactive agents and to detect more active regimens sooner, investigators found that... 
DRUG DEVELOPMENT | TRIALS | MEDICINE, GENERAL & INTERNAL | MODEL | NEOADJUVANT CHEMOTHERAPY | PATHOLOGICAL COMPLETE RESPONSE | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Carboplatin - administration & dosage | Paclitaxel - adverse effects | Poly(ADP-ribose) Polymerase Inhibitors - adverse effects | Triple Negative Breast Neoplasms - drug therapy | Poly(ADP-ribose) Polymerase Inhibitors - administration & dosage | Carboplatin - adverse effects | Benzimidazoles - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Triple Negative Breast Neoplasms - surgery | Bayes Theorem | Adult | Female | Neoadjuvant Therapy | Aged | Benzimidazoles - adverse effects | Paclitaxel - administration & dosage | Care and treatment | Usage | Patient outcomes | Carboplatin | Clinical trials | Dosage and administration | Breast cancer | Diagnosis | Toxicity | Poly(ADP-ribose) | Poly(ADP-ribose) polymerase | Cancer therapies | Patients | ErbB-2 protein | Chemotherapy | Epidermal growth factor | Magnetic resonance imaging | Ribose | Biomarkers | Bayesian analysis | Tumors
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8. Full Text Omission of doxorubicin from the treatment of stage II–III, intermediate-risk Wilms' tumour (SIOP WT 2001): an open-label, non-inferiority, randomised controlled trial
by Pritchard-Jones, Kathy, Prof and Bergeron, Christophe, MD and de Camargo, Beatriz, MD and van den Heuvel-Eibrink, Marry M, MD and Acha, Tomas, MD and Godzinski, Jan, MD and Oldenburger, Foppe, MD and Boccon-Gibod, Liliane, MD and Leuschner, Ivo, Prof and Vujanic, Gordan, Prof and Sandstedt, Bengt, MD and de Kraker, Jan, MD and van Tinteren, Harm, PhD and Graf, Norbert, MD and SIOP Renal Tumours Study Grp and SIOP Renal Tumours Study Group
Lancet, The, ISSN 0140-6736, 2015, Volume 386, Issue 9999, pp. 1156 - 1164
Summary Background Before this study started, the standard postoperative chemotherapy regimen for stage II–III Wilms' tumour pretreated with chemotherapy was... 
Internal Medicine | FAVORABLE-HISTOLOGY | MEDICINE, GENERAL & INTERNAL | CHILDHOOD-CANCER | INTERNATIONAL-SOCIETY | CARDIAC EVENTS | RENAL TUMORS | SURVIVORS | PEDIATRIC-ONCOLOGY | CHEMOTHERAPY | EQUIVALENCE | CHILDREN | Humans | Wilms Tumor - drug therapy | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Child, Preschool | Infant | Male | Kidney Neoplasms - surgery | Nephrectomy | Chemotherapy, Adjuvant - adverse effects | Dactinomycin - adverse effects | Vincristine - administration & dosage | Female | Child | Doxorubicin - administration & dosage | Kaplan-Meier Estimate | Treatment Outcome | Dactinomycin - administration & dosage | Wilms Tumor - pathology | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Chemotherapy, Adjuvant - methods | Neoadjuvant Therapy - adverse effects | Neoadjuvant Therapy - methods | Adolescent | Vincristine - adverse effects | Kidney Neoplasms - pathology | Kidney Neoplasms - drug therapy | Neoplasm Staging | Doxorubicin - adverse effects | Wilms Tumor - surgery | Care and treatment | Chemotherapy | Anthracyclines | Children | Health aspects | Tumors | Cancer | Histology | Biopsy | Medical prognosis | Clinical outcomes | Medical and Health Sciences | Medicin och hälsovetenskap
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9. Full Text Preoperative Modified FOLFIRINOX Treatment Followed by Capecitabine-Based Chemoradiation for Borderline Resectable Pancreatic Cancer: Alliance for Clinical Trials in Oncology Trial A021101
by Katz, Matthew H. G and Shi, Qian and Ahmad, Syed A and Herman, Joseph M and Marsh, Robert de W and Collisson, Eric and Schwartz, Lawrence and Frankel, Wendy and Martin, Robert and Conway, William and Truty, Mark and Kindler, Hedy and Lowy, Andrew M and Bekaii-Saab, Tanios and Philip, Philip and Talamonti, Mark and Cardin, Dana and LoConte, Noelle and Shen, Perry and Hoffman, John P and Venook, Alan P
JAMA Surgery, ISSN 2168-6254, 08/2016, Volume 151, Issue 8, pp. e161137 - e161137
IMPORTANCE: Although consensus statements support the preoperative treatment of borderline resectable pancreatic cancer, no prospective, quality-controlled,... 
ADJUVANT CHEMOTHERAPY | SURGERY | STANDARDIZATION | NEOADJUVANT FOLFIRINOX | THERAPY | EXPERT CONSENSUS STATEMENT | EFFICACY | DUCTAL ADENOCARCINOMA | RESECTION | RANDOMIZED CONTROLLED-TRIAL | GEMCITABINE | Capecitabine - administration & dosage | Leucovorin - administration & dosage | Chemoradiotherapy - adverse effects | Prospective Studies | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Radiotherapy, Intensity-Modulated - adverse effects | Feasibility Studies | Neoplasm, Residual | Organoplatinum Compounds - administration & dosage | Fluorouracil - administration & dosage | Camptothecin - administration & dosage | Female | Neoadjuvant Therapy | Camptothecin - analogs & derivatives | Chemoradiotherapy - methods | Pancreatic Neoplasms - pathology | Margins of Excision | Pancreatectomy | Survival Rate | Carcinoma, Pancreatic Ductal - therapy | Carcinoma, Pancreatic Ductal - pathology | Pilot Projects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Aged | Pancreatic Neoplasms - therapy
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