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neodysiherbaine-a (3) 3
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Letters in Organic Chemistry, ISSN 1570-1786, 05/2017, Volume 14, Issue 4, pp. 261 - 266
Journal Article
Neuropharmacology, ISSN 0028-3908, 03/2010, Volume 58, Issue 3, pp. 640 - 649
.... Synthetic modification of the convulsant marine toxin neodysiherbaine A (NDH) previously yielded molecules with a diverse set of pharmacological actions on kainate receptors... 
Electrophysiology | Synthetic | Glutamate receptor | Marine natural product | Radioligand binding | Ligand-binding domain | LIGAND-BINDING CORE | SPONGE DYSIDEA-HERBACEA | CRYSTAL-STRUCTURES | NEUROSCIENCES | MARINE SPONGE | GENETIC ALGORITHM | N-3-SUBSTITUTED WILLARDIINE DERIVATIVES | AMINO-ACID | ANIMAL-MODELS | PHARMACOLOGY & PHARMACY | PARTICLE-MESH EWALD | NEODYSIHERBAINE-A | Receptors, Kainic Acid - chemistry | Humans | Mutagenesis, Site-Directed - methods | Green Fluorescent Proteins - genetics | Receptors, Kainic Acid - genetics | Structure-Activity Relationship | Receptors, Kainic Acid - agonists | Patch-Clamp Techniques - methods | Dose-Response Relationship, Drug | Alanine - analogs & derivatives | Transfection - methods | Time Factors | Radioligand Assay - methods | Molecular Structure | Alanine - pharmacology | Protein Subunits - genetics | Membrane Potentials - drug effects | Glutamic Acid - pharmacology | Models, Molecular | Excitatory Amino Acid Agonists - pharmacology | Molecular Dynamics Simulation | Binding, Competitive - drug effects | alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid - pharmacokinetics | Receptors, Kainic Acid - metabolism | Bridged Bicyclo Compounds, Heterocyclic - pharmacology | Kainic Acid - pharmacokinetics | Ligands | Cell Line, Transformed | Tritium - pharmacokinetics | Index Medicus | synthetic | radioligand binding | electrophysiology | marine natural product | glutamate receptor | ligand-binding domain
Journal Article
European Journal of Organic Chemistry, ISSN 1434-193X, 10/2012, Volume 2012, Issue 29, pp. 5789 - 5802
... neodysiherbaine (NDH), 3 dysibetaine (DB), 4 and dysibetaines CPa (DBCPa, 1 ) and CPb (DBCPb, 2 ). 5 DH and NDH are glutamate analogs with potent convulsant activity. 6 DH... 
Amino acids | Natural products | Chemoselectivity | Neurological agents | Total synthesis | Diastereoselectivity | DYSIBETAINE | DYSIHERBAINE | ENANTIOSELECTIVE SYNTHESIS | CHEMISTRY, ORGANIC | NEODYSIHERBAINE-A | EXCITATORY AMINO-ACIDS | Accountants | Synthesis | Universities and colleges | Cyclopropane compounds | Organic compounds
Journal Article
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