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American Journal of Physiology - Renal Physiology, ISSN 0363-6127, 07/2012, Volume 303, Issue 2, pp. F209 - F219
Journal Article
Journal of the American Society of Nephrology, ISSN 1046-6673, 11/2017, Volume 28, Issue 11, pp. 3133 - 3135
Journal Article
11/2010
Hedgehog (HH) signaling controls renal development. Mutations in PTC1, the HH receptor, cause cancer in non-renal tissues. We hypothesized that constitutively... 
0719 | Kidney, Hedgehog, Patched, Mesenchyme, UPJ, Gli, HH, Nephrogenesis
Dissertation
Journal of Hypertension, ISSN 0263-6352, 2016, Volume 34, Issue 10, pp. 1988 - 1997
Journal Article
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, ISSN 1046-6673, 07/2019, Volume 30, Issue 7, pp. 1192 - 1205
Background Nephron progenitors, the cell population that give rise to the functional unit of the kidney, are metabolically active and self-renew under... 
MORPHOGENESIS | ACTIVATION | NUMBER | NEPHROGENESIS | TRANSCRIPTION | UROLOGY & NEPHROLOGY | SELF-RENEWAL | VHL | KIDNEY | HYPOXIA | SUPPRESSION
Journal Article
European Journal of Histochemistry, ISSN 1121-760X, 09/2019, Volume 63, Issue 3
Nephron progenitors (NPs) and nephrogenesis have been extensively studied in mice and humans and have provided insights into the mechanisms of renal... 
nephrogenesis | Nephron progenitor | renal development
Journal Article
Kidney International, ISSN 0085-2538, 02/2000, Volume 57, Issue 2, pp. 414 - 422
  Antenatal exposure to nonsteroidal anti-inflammatory drugs (NSAIDs) has been associated with renal dysgenesis in humans. These studies characterized... 
Cyclooxygenase | Prostaglandins | Macula densa | NSAIDs | Nephrogenesis
Journal Article
Andrologiâ i Genitalʹnaâ Hirurgiâ, ISSN 2070-9781, 11/2014, Volume 14, Issue 4, pp. 45 - 48
Kidney biopsies obtained from 3 days – 12 years children with congenital hydronephrosis during nephrectomy operation were investigated under the light... 
nephrogenesis | growth factors | angiogenesis
Journal Article
DEVELOPMENTAL BIOLOGY, ISSN 0012-1606, 01/2008, Volume 313, Issue 1, pp. 234 - 245
Classic tissue recombination and in vitro lineage tracing studies suggest that condensed metanephric mesenchyme (MM) gives rise to nephronic epithelium of the... 
SYSTEM | cap mesenchyme | NEPHROGENESIS | MOUSE | DISTINCT | CRE RECOMBINASE | metanephric mesenchyme | DEVELOPMENTAL BIOLOGY | lineage tracing | INDUCTION | BMP5 | kidney development | cited1 BAC transgenic mice | GENE-EXPRESSION | EFFICIENT
Journal Article
Journal of the American Society of Nephrology, ISSN 1046-6673, 03/2018, Volume 29, Issue 3, pp. 825 - 840
The nephron is the functional unit of the kidney, but the mechanism of nephron formation during human development is unclear. We conducted a detailed analysis... 
CELLS | MORPHOGENESIS | DEVELOPING KIDNEY | NEPHROGENESIS | METANEPHRIC MESENCHYME | GENE-EXPRESSION | UROLOGY & NEPHROLOGY | DIFFERENTIATION | IDENTIFICATION | EPITHELIAL TRANSFORMATION | EARLY ORGANOGENESIS | nephron | human genetics | kidney development | Basic Research
Journal Article
Biology Open, ISSN 2046-6390, 2019, Volume 8, Issue 5, p. bio042754
Six2+ cap mesenchyme cells, also called nephron progenitor cells (NPC), are precursors of all epithelial cell types of the nephron, the filtering unit of the... 
ChIP-seq | Epigenetics | ATAC-seq | Kidney | Nephrogenesis
Journal Article
Cell Reports, ISSN 2211-1247, 04/2016, Volume 15, Issue 4, pp. 801 - 813
Nephron progenitors in the embryonic kidney propagate while generating differentiated nephrons. However, in mice, the progenitors terminally differentiate... 
NEPHROGENESIS | SIX2 | MAINTAIN | SELF-RENEWAL | MOUSE KIDNEY | DIFFERENTIATION | INDUCTION | MESENCHYME | ORGANOGENESIS | ORGANOIDS | CELL BIOLOGY
Journal Article
Nature Protocols, ISSN 1754-2189, 09/2016, Volume 11, Issue 9, pp. 1681 - 1692
Journal Article
Hypertension Research, ISSN 0916-9636, 2019, Volume 42, Issue 6, pp. 779 - 789
We previously reported that rats treated with an NF-κB inhibitor, pyrrolidine dithiocarbamate (PDTC), during lactation developed hypertension in adult life,... 
nephrogenesis | chronic kidney disease | malignant hypertension | NF-kB system | renal injury
Journal Article
Journal of the American Society of Nephrology, ISSN 1046-6673, 11/2006, Volume 17, Issue 11, pp. 3028 - 3040
Acute kidney injury is followed by regeneration of damaged renal tubular epithelial cells. The purpose of this study was to test the hypothesis that renal stem... 
MARROW | REGENERATION | NEPHROGENESIS | POSTISCHEMIC KIDNEY | GENE-EXPRESSION | UROLOGY & NEPHROLOGY | ACUTE-RENAL-FAILURE | ADULT KIDNEY | DIFFERENTIATION | IDENTIFICATION | NEPHRON | Animals | Multipotent Stem Cells - cytology | Rats, Inbred F344 | Cells, Cultured | Rats | Cell Differentiation | Kidney - cytology
Journal Article
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