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Journal Article
Neuron, ISSN 0896-6273, 02/2004, Volume 41, Issue 4, pp. 489 - 491
The function and regulation of actin-cytoskeletal dynamics during synaptic growth is poorly understood. In this issue of Neuron, Coyle et al. report the... 
nervous wreck protein | WASP protein
Journal Article
Neuron, ISSN 0896-6273, 02/2004, Volume 41, Issue 4, pp. 521 - 534
We describe the isolation and characterization of nwk (nervous wreck), a temperature-sensitive paralytic mutant that causes excessive growth of larval... 
nervous wreck protein | Wsp protein | WASP protein
Journal Article
Journal Article
BBA - Molecular Cell Research, ISSN 0167-4889, 01/2017, Volume 1864, Issue 1, pp. 23 - 30
Intersectins (ITSNs) are a family of multi-domain proteins involved in regulation of diverse cellular pathways. These scaffold proteins are well known for... 
Endocytosis | Scaffold | Intersectin | Actin | Neurons | Cancer | CLATHRIN-MEDIATED ENDOCYTOSIS | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | NERVOUS WRECK | EH-DOMAIN | PLASMA-MEMBRANE | EPS15 HOMOLOGY | CELL BIOLOGY | GROWTH-FACTOR RECEPTOR | DENDRITIC SPINE DEVELOPMENT | RHO GTPASES | ADAPTER PROTEIN | Protein Kinases - metabolism | Lung Injury - pathology | Protein Kinases - genetics | Down Syndrome - metabolism | Cytoskeletal Proteins - genetics | Humans | Adaptor Proteins, Vesicular Transport - genetics | Brain Neoplasms - pathology | Adaptor Proteins, Vesicular Transport - metabolism | Brain Neoplasms - metabolism | Oncogene Protein p21(ras) - metabolism | Alzheimer Disease - pathology | Protein Isoforms - metabolism | Glioblastoma - genetics | Lung Injury - metabolism | Cytoskeletal Proteins - metabolism | Glioblastoma - metabolism | Endocytosis - genetics | Neuroblastoma - pathology | Down Syndrome - pathology | Signal Transduction | Neuroblastoma - genetics | Gene Expression Regulation | Brain Neoplasms - genetics | Lung Injury - genetics | Animals | Glioblastoma - pathology | Alzheimer Disease - metabolism | Down Syndrome - genetics | Neuroblastoma - metabolism | Alzheimer Disease - genetics | Oncogene Protein p21(ras) - genetics | Protein Isoforms - genetics | Nervous system diseases | Chromatin | Cellular signal transduction | Binding proteins | Protein binding
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2010, Volume 107, Issue 40, pp. 17379 - 17384
Phosphatidylinositol-4,5-bisphosphate [PI(4,5)P₂] is a membrane lipid involved in several signaling pathways. However, the role of this lipid in the regulation... 
Larvae | Receptors | Quantification | Neurons | Microfilaments | Drosophila | Actins | Physiological regulation | Larval development | Synapses | Synapse formation | Wishful thinking | Neuromuscular junction | Nervous wreck | Tweek | DROSOPHILA NEUROMUSCULAR-JUNCTION | Wishful Thinking | MULTIDISCIPLINARY SCIENCES | ALDRICH-SYNDROME PROTEIN | PLASMA-MEMBRANE | synapse formation | MAD | Nervous Wreck | neuromuscular junction | INTERACTS | II RECEPTOR | PLECKSTRIN HOMOLOGY DOMAIN | ACTIN CYTOSKELETON | FUNCTION REQUIRE | Wiskott-Aldrich Syndrome Protein - genetics | Drosophila melanogaster - physiology | Presynaptic Terminals - ultrastructure | Drosophila Proteins - metabolism | Recombinant Fusion Proteins - metabolism | Phosphatidylinositol 4,5-Diphosphate - metabolism | Bone Morphogenetic Proteins - metabolism | Wiskott-Aldrich Syndrome Protein - metabolism | Microfilament Proteins - metabolism | Drosophila melanogaster - anatomy & histology | Bone Morphogenetic Proteins - genetics | Microfilament Proteins - genetics | Synapses - physiology | Receptors, Cell Surface - metabolism | Synapses - ultrastructure | Nerve Tissue Proteins - genetics | Neuromuscular Junction - ultrastructure | Nerve Tissue Proteins - metabolism | Patch-Clamp Techniques | Animals | Presynaptic Terminals - metabolism | Recombinant Fusion Proteins - genetics | Signal Transduction - physiology | Drosophila Proteins - genetics | Neuromuscular Junction - physiology | Receptors, Cell Surface - genetics | Presynapse | Signal transduction | Synaptogenesis | Actin | spike protein | Bone morphogenetic proteins | Lipids | Neuromuscular junctions | moesin | Phosphatidylinositol 4,5-diphosphate | Biological Sciences
Journal Article
Journal Article