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Biochemical Journal, ISSN 0264-6021, 05/2011, Volume 435, Issue 3, pp. 609 - 618
NRP1 (neuropilin-1) is a co-receptor for members of the VEGF (vascular endothelial growth factor) family in endothelial cells, but is increasingly implicated... 
Platelet-derived growth factor (PDGF) | Glycosylation | Neuropilin-1 (NRP1) | Chemotaxis | p130 | Vascular endothelial growth factor (VEGF) | ANGIOGENESIS | VEGF | BIOCHEMISTRY & MOLECULAR BIOLOGY | glycosylation | vascular endothelial growth factor (VEGF) | RECEPTOR | TUMOR-CELLS | platelet-derived growth factor (PDGF) | neuropilin-1 (NRP1) | SEMAPHORIN-III | p130(Cas) | BINDING | chemotaxis | ENDOTHELIAL GROWTH-FACTOR | Neuropilin-1 - genetics | Adenoviridae | Endothelial Cells | Neuropilin-1 - metabolism | Humans | Cells, Cultured | Crk-Associated Substrate Protein - metabolism | Muscle, Smooth, Vascular - cytology | Platelet-Derived Growth Factor - genetics | Crk-Associated Substrate Protein - genetics | Platelet-Derived Growth Factor - metabolism | Signal Transduction - physiology | Mutation | Myocytes, Smooth Muscle - cytology | Myocytes, Smooth Muscle - metabolism | Cell Movement | HAoSMC, human aortic smooth muscle cell | Ad.NRP1ΔC, adenovirus expressing neuropilin-1 mutant lacking the intracellular domain | Cas, Crk-associated substrate | Ad.NRP1S612A, adenovirus expressing S612A mutant neuropilin-1 | PAE cell, porcine aortic endothelial cell | NRP1, neuropilin-1 | VEGFR2, VEGF receptor 2 | PDGFR, PDGF receptor | ERK, extracellular-signal-regulated kinase | NRP1 cell, PAE cell expressing NRP1 | HCASMC, human coronary artery smooth muscle cell | HCAEC, human coronary artery endothelial cell | HUVEC, human umbilical vein endothelial cell | CS, chondroitin sulfate | GAPDH, glyceraldehyde-3-phosphate dehydrogenase | VSMC, vascular smooth muscle cell | FBS, fetal bovine serum | Ad.NRP1WT, adenovirus expressing wild-type neuropilin 1 | GAG, glycosaminoglycan | VEGF, vascular endothelial growth factor | p130Cas | siRNA, small interfering RNA | HS, heparan sulfate | PAE | Ad.GFP, adenovirus expressing green fluorescent protein | PDGF, platelet-derived growth factor
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 06/2017, Volume 292, Issue 24, pp. 10295 - 10305
Journal Article
Nature, ISSN 0028-0836, 2013, Volume 501, Issue 7466, pp. 252 - 256
Regulatory T cells (T-reg cells) have a crucial role in the immune system by preventing autoimmunity, limiting immunopathology, and maintaining immune... 
PLASMACYTOID DENDRITIC CELLS | BREAST-CANCER CELLS | ACTIVATION | NEUROPILIN-1 | MARKER | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION FACTOR FOXP3 | IN-VIVO | AKT | DIFFERENTIATION | EXPRESSION | T-Lymphocytes, Regulatory - metabolism | Phosphorylation | TOR Serine-Threonine Kinases - metabolism | Neuropilin-1 - metabolism | Humans | Male | T-Lymphocytes, Regulatory - immunology | Neoplasms - genetics | Autoimmunity - immunology | Forkhead Transcription Factors - metabolism | Immune Tolerance - immunology | HEK293 Cells | T-Lymphocytes, Regulatory - cytology | Female | Lymphocytes, Tumor-Infiltrating - metabolism | Colitis - immunology | Proto-Oncogene Proteins c-akt - metabolism | Lymphocytes, Tumor-Infiltrating - cytology | Signal Transduction | Cell Survival | Mice, Inbred C57BL | Homeostasis - immunology | PTEN Phosphohydrolase - metabolism | Semaphorins - metabolism | Immunological Synapses | Animals | Neoplasms - immunology | Mice | Forkhead Box Protein O3 | Neoplasms - pathology | Neuropilin-1 - deficiency | Lymphocytes, Tumor-Infiltrating - immunology | Immunosuppression | Semaphorins | Homeostasis | Physiological aspects | Research | T cells | Properties | Proteins | Immunology | Lymphocytes | Rodents | Melanoma | Kinases | Autoimmune diseases | Laboratory animals | Vascular endothelial growth factor | Cell adhesion & migration
Journal Article
Circulation Research, ISSN 0009-7330, 08/2012, Volume 111, Issue 4, pp. 426 - 436
Journal Article
Circulation Research, ISSN 0009-7330, 08/2012, Volume 111, Issue 4, pp. 437 - 445
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 03/2012, Volume 209, Issue 3, pp. 507 - 520
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 06/2015, Volume 290, Issue 26, pp. 16451 - 16462
Journal Article
International Journal of Oncology, ISSN 1019-6439, 09/2016, Volume 49, Issue 3, pp. 961 - 970
Journal Article
Cellular Physiology and Biochemistry, ISSN 1015-8987, 12/2017, Volume 44, Issue 3, pp. 1251 - 1262
Background/Aims: Targeting cancer stem cells (CSCs) is emerging as a promising method for cancer treatment. We previously indicated that knockdown of... 
Original Paper | Nrp-1 VEGF-A Wnt/β-catenin CSCs breast cancer doxorubicin | INDUCED VASCULOGENESIS | PHYSIOLOGY | NEUROPILIN-1 | BONE METASTASIS | SUPPRESSES | PROLIFERATION | GENERATION | Nrp-1 VEGF-A Wnt/beta-catenin CSCs breast cancer doxorubicin | PROGRESSION | ENDOTHELIAL GROWTH-FACTOR | CELL BIOLOGY | Human Umbilical Vein Endothelial Cells | Neuropilin-1 - genetics | Wnt3A Protein - metabolism | Neoplastic Stem Cells - cytology | Neuropilin-1 - metabolism | Coculture Techniques | Humans | Transplantation, Heterologous | Vascular Endothelial Growth Factor A - metabolism | Spheroids, Cellular - cytology | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Vascular Endothelial Growth Factor A - genetics | Neuropilin-1 - antagonists & inhibitors | Breast Neoplasms - metabolism | MCF-7 Cells | Neoplastic Stem Cells - metabolism | RNA Interference | Female | Real-Time Polymerase Chain Reaction | Wnt3A Protein - genetics | Spheroids, Cellular - metabolism | beta Catenin - metabolism | Disease Progression | Doxorubicin - toxicity | beta Catenin - genetics | Phenotype | Animals | Wnt Signaling Pathway - drug effects | Breast Neoplasms - pathology | Mice, Nude | Cell Line, Tumor | Mice | Neovascularization, Physiologic | Cell Movement | Drug Resistance, Neoplasm - drug effects | RNA, Small Interfering - metabolism | Nrp-1 | VEGF-A | Wnt/β-catenin CSCs breast cancer doxorubicin
Journal Article
Biochemical Journal, ISSN 0264-6021, 04/2010, Volume 427, Issue 1, pp. 29 - 40
Using human MSCs (mesenchymal stem cells) lacking VEGF (vascular endothelial growth factor) receptors, we show that the pro-angiogenic receptor neuropilin-1... 
Mesenchymal stem cell | Neuropilin-1 | Co-localization | Migration | Network assembly | Platelet-derived growth factor receptor | VASCULAR DEVELOPMENT | mesenchymal stem cell | ANGIOGENESIS | VEGF | BIOCHEMISTRY & MOLECULAR BIOLOGY | neuropilin-1 | AUTOCRINE | ENDOTHELIAL-CELLS | DISEASE | migration | platelet-derived growth factor receptor | PDGF-ALPHA-RECEPTOR | network assembly | co-localization | BINDING | EXPRESSION | Neuropilin-1 - genetics | Phosphorylation | Cell Proliferation | Immunoprecipitation | Neuropilin-1 - metabolism | Humans | Vascular Endothelial Growth Factor A - metabolism | RNA, Messenger - metabolism | Receptor, Platelet-Derived Growth Factor beta - genetics | Vascular Endothelial Growth Factor A - genetics | Platelet-Derived Growth Factor - genetics | Immunoenzyme Techniques | Neuropilin-1 - antagonists & inhibitors | Receptor, Platelet-Derived Growth Factor beta - metabolism | Receptor, Platelet-Derived Growth Factor alpha - metabolism | Proto-Oncogene Proteins c-sis | RNA, Messenger - genetics | RNA, Small Interfering - pharmacology | Mesenchymal Stromal Cells - metabolism | Chorioallantoic Membrane - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Platelet-Derived Growth Factor - metabolism | Animals | Receptor, Platelet-Derived Growth Factor alpha - genetics | Chickens | Cell Movement | NA, numerical aperture | NRP-1, neuropilin-1 | p-, phosphorylated | VEGF, vascular endothelial growth factor | RT, reverse transcription | DAPI, 4′,6-diamidino-2-phenylindole | siRNA, small interfering RNA | PDGFR, PDGF receptor | ES, embryonic stem | VEGFR, VEGF receptor | HGF, hepatocyte growth factor | MSC, mesenchymal stem cell | PDGF, platelet-derived growth factor | HUVEC, human umbilical vein endothelial cell | CAM, chorioallantoic membrane
Journal Article