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1. Full Text Neuropilin-1 mediates PDGF stimulation of vascular smooth muscle cell migration and signalling via p130Cas
by Pellet-Many, Caroline and Frankel, Paul and Evans, Ian M and Herzog, Birger and Jünemann-Ramírez, Manfred and Zachary, Ian C
Biochemical Journal, ISSN 0264-6021, 05/2011, Volume 435, Issue 3, pp. 609 - 618
NRP1 (neuropilin-1) is a co-receptor for members of the VEGF (vascular endothelial growth factor) family in endothelial cells, but is increasingly implicated... 
Platelet-derived growth factor (PDGF) | Glycosylation | Neuropilin-1 (NRP1) | Chemotaxis | p130 | Vascular endothelial growth factor (VEGF) | ANGIOGENESIS | VEGF | BIOCHEMISTRY & MOLECULAR BIOLOGY | glycosylation | vascular endothelial growth factor (VEGF) | RECEPTOR | TUMOR-CELLS | platelet-derived growth factor (PDGF) | neuropilin-1 (NRP1) | SEMAPHORIN-III | p130(Cas) | BINDING | chemotaxis | ENDOTHELIAL GROWTH-FACTOR | Neuropilin-1 - genetics | Adenoviridae | Endothelial Cells | Neuropilin-1 - metabolism | Humans | Cells, Cultured | Crk-Associated Substrate Protein - metabolism | Muscle, Smooth, Vascular - cytology | Platelet-Derived Growth Factor - genetics | Crk-Associated Substrate Protein - genetics | Platelet-Derived Growth Factor - metabolism | Signal Transduction - physiology | Mutation | Myocytes, Smooth Muscle - cytology | Myocytes, Smooth Muscle - metabolism | Cell Movement | HAoSMC, human aortic smooth muscle cell | Ad.NRP1ΔC, adenovirus expressing neuropilin-1 mutant lacking the intracellular domain | Cas, Crk-associated substrate | Ad.NRP1S612A, adenovirus expressing S612A mutant neuropilin-1 | PAE cell, porcine aortic endothelial cell | NRP1, neuropilin-1 | VEGFR2, VEGF receptor 2 | PDGFR, PDGF receptor | ERK, extracellular-signal-regulated kinase | NRP1 cell, PAE cell expressing NRP1 | HCASMC, human coronary artery smooth muscle cell | HCAEC, human coronary artery endothelial cell | HUVEC, human umbilical vein endothelial cell | CS, chondroitin sulfate | GAPDH, glyceraldehyde-3-phosphate dehydrogenase | VSMC, vascular smooth muscle cell | FBS, fetal bovine serum | Ad.NRP1WT, adenovirus expressing wild-type neuropilin 1 | GAG, glycosaminoglycan | VEGF, vascular endothelial growth factor | p130Cas | siRNA, small interfering RNA | HS, heparan sulfate | PAE | Ad.GFP, adenovirus expressing green fluorescent protein | PDGF, platelet-derived growth factor
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2. Full Text Impeding Macrophage Entry into Hypoxic Tumor Areas by Sema3A/Nrp1 Signaling Blockade Inhibits Angiogenesis and Restores Antitumor Immunity
by Casazza, Andrea and Laoui, Damya and Wenes, Mathias and Rizzolio, Sabrina and Bassani, Nicklas and Mambretti, Marco and Deschoemaeker, Sofie and Van Ginderachter, Jo A and Tamagnone, Luca and Mazzone, Massimiliano
Cancer Cell, ISSN 1535-6108, 12/2013, Volume 24, Issue 6, pp. 695 - 709
Recruitment of tumor-associated macrophages (TAMs) into avascular areas sustains tumor progression; however, the underlying guidance mechanisms are unknown.... 
NEUROPILIN-1 | ONCOLOGY | INFLAMMATION | REGULATORY T-CELLS | AXON GUIDANCE | GENE-EXPRESSION | THERAPEUTIC TARGETS | RECEPTOR | SEMAPHORIN 3A | CANCER | ENDOTHELIAL GROWTH-FACTOR | CELL BIOLOGY | Macrophages - physiology | Neuropilin-1 - genetics | Neuropilin-1 - antagonists & inhibitors | Mice, Knockout | Cell Hypoxia | Neoplasms, Experimental - pathology | Neuropilin-1 - physiology | Animals | Semaphorin-3A - physiology | Neoplasms, Experimental - immunology | Macrophages - drug effects | Neovascularization, Pathologic - prevention & control | Signal Transduction - physiology | Mice | Semaphorin-3A - antagonists & inhibitors | Neoplasms, Experimental - blood supply | Development and progression | Endothelial growth factors | Macrophages | Tumors
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3. Full Text NRP1 acts cell autonomously in endothelium to promote tip cell function during sprouting angiogenesis
by Fantin, Alessandro and Fantin, Alessandro and Vieira, Joaquim M and Vieira, Joaquim M and Plein, Alice and Plein, Alice and Denti, Laura and Denti, Laura and Fruttiger, Marcus and Fruttiger, Marcus and Pollard, Jeffrey W and Pollard, Jeffrey W and Ruhrberg, Christiana and Ruhrberg, Christiana
Blood, ISSN 0006-4971, 03/2013, Volume 121, Issue 12, pp. 2352 - 2362
Neuropilin (NRP) 1 is a receptor for the vascular endothelial growth factor (VEGF)-A and is essential for normal angiogenesis. Previous in vitro experiments... 
VASCULAR DEVELOPMENT | NERVOUS-SYSTEM | NEUROPILIN-1 | VEGF | SEMAPHORIN | MOUSE | GROWTH-FACTOR RECEPTOR-2 | REQUIRES | MICE | HEMATOLOGY | BINDING | Endothelium, Vascular - cytology | Neuropilin-1 - genetics | Blood Vessels - growth & development | Morphogenesis - genetics | Embryo, Mammalian | Endothelial Cells - metabolism | Neovascularization, Physiologic - genetics | Neuropilin-1 - metabolism | Blood Vessels - metabolism | Mice, Transgenic | Blood Vessels - embryology | Neuropilin-1 - physiology | Pregnancy | Cell Polarity - genetics | Organ Specificity - genetics | Animals | Endothelial Cells - cytology | Endothelium, Vascular - metabolism | Models, Biological | Female | Mice | Endothelial Cells - physiology | Vascular Biology
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4. Full Text Neuropilin-1 mediates neutrophil elastase uptake and cross-presentation in breast cancer cells
by Kerros, Celine and Tripathi, Satyendra C and Zha, Dongxing and Mehrens, Jennifer M and Sergeeva, Anna and Philips, Anne V and Qiao, Na and Peters, Haley L and Katayama, Hiroyuki and Sukhumalchandra, Pariya and Ruisaard, Kathryn E and Perakis, Alexander A and St John, Lisa S and Lu, Sijie and Mittendorf, Elizabeth A and Clise-Dwyer, Karen and Herrmann, Amanda C and Alatrash, Gheath and Toniatti, Carlo and Hanash, Samir M and Ma, Qing and Molldrem, Jeffrey J
Journal of Biological Chemistry, ISSN 0021-9258, 06/2017, Volume 292, Issue 24, pp. 10295 - 10305
Neutrophil elastase (NE) can be rapidly taken up by tumor cells that lack endogenous NE expression, including breast cancer, which results in... 
IMMUNE-RESPONSE | BIOCHEMISTRY & MOLECULAR BIOLOGY | END-RULE PEPTIDES | RECEPTOR | CATHEPSIN-G | MYELOID MALIGNANCIES | LEUKEMIA | T-CELLS | PR1 | PROGRESSION | ENDOTHELIAL GROWTH-FACTOR | Leukocyte Elastase - metabolism | Neuropilin-1 - genetics | Antibodies, Blocking - metabolism | Breast Neoplasms - immunology | Neuropilin-1 - metabolism | Absorption, Physiological | Humans | Neoplasm Proteins - antagonists & inhibitors | Neoplasm Proteins - metabolism | Neuropilin-1 - antagonists & inhibitors | Breast Neoplasms - metabolism | Neuropilin-1 - chemistry | RNA Interference | Female | Protein Interaction Domains and Motifs | Neoplasm Proteins - genetics | Peptide Fragments - genetics | Recombinant Proteins - metabolism | T-Lymphocytes, Cytotoxic - immunology | Peptide Fragments - metabolism | Solubility | Recombinant Proteins - chemistry | Neoplasm Proteins - chemistry | Amino Acid Motifs | Peptide Fragments - chemistry | Leukocyte Elastase - chemistry | T-Lymphocytes, Cytotoxic - metabolism | Breast Neoplasms - pathology | CRISPR-Cas Systems | Cell Line, Tumor | Cross-Priming | Ligands | Kinetics | Leukocyte Elastase - immunology | antigen presentation | cross-presentation | receptor internalization | neutrophil elastase | immunotherapy | neuropilin-1 | breast cancer | serine protease | Cell Biology
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5. Full Text A vascular niche and a VEGF-Nrp1 loop regulate the initiation and stemness of skin tumours
by Beck, Benjamin and Driessens, Gregory and Goossens, Steven and Youssef, Khalil Kass and Kuchnio, Anna and Caauwe, Amélie and Sotiropoulou, Panagiota A and Loges, Sonja and Lapouge, Gaelle and Candi, Aurélie and Mascre, Guilhem and Drogat, Benjamin and Dekoninck, Sophie and Haigh, Jody J and Carmeliet, Peter and Blanpain, Cédric
Nature, ISSN 0028-0836, 10/2011, Volume 478, Issue 7369, pp. 399 - 403
Angiogenesis is critical during tumour initiation and malignant progression(1). Different strategies aimed at blocking vascular endothelial growth factor... 
CELLS | ANGIOGENESIS | NEUROPILIN-1 | ENDOTHELIAL-GROWTH-FACTOR | MULTIDISCIPLINARY SCIENCES | CATENIN | MICE | DIFFERENTIATION | VEGF-A | CANCER | MOUSE SKIN | Neuropilin-1 - genetics | Skin Neoplasms - pathology | Cell Proliferation | Signal Transduction | Neuropilin-1 - metabolism | Carcinoma, Squamous Cell - pathology | Cells, Cultured | Gene Expression Regulation, Neoplastic | Neoplastic Stem Cells | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - genetics | Animals | Gene Deletion | Carcinoma, Squamous Cell - blood supply | Cell Differentiation | Mice | Skin Neoplasms - blood supply | Epithelial Cells - cytology | Disease Models, Animal
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6. Full Text Stability and function of regulatory T cells is maintained by a neuropilin-1-semaphorin-4a axis
by Delgoffe, Greg M and Woo, Seng-Ryong and Turnis, Meghan E and Gravano, David M and Guy, Cliff and Overacre, Abigail E and Bettini, Matthew L and Vogel, Peter and Finkelstein, David and Bonnevier, Jody and Workman, Creg J and Vignali, Dario A. A
Nature, ISSN 0028-0836, 2013, Volume 501, Issue 7466, pp. 252 - 256
Regulatory T cells (T-reg cells) have a crucial role in the immune system by preventing autoimmunity, limiting immunopathology, and maintaining immune... 
PLASMACYTOID DENDRITIC CELLS | BREAST-CANCER CELLS | ACTIVATION | NEUROPILIN-1 | MARKER | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION FACTOR FOXP3 | IN-VIVO | AKT | DIFFERENTIATION | EXPRESSION | T-Lymphocytes, Regulatory - metabolism | Phosphorylation | TOR Serine-Threonine Kinases - metabolism | Neuropilin-1 - metabolism | Humans | Male | T-Lymphocytes, Regulatory - immunology | Neoplasms - genetics | Autoimmunity - immunology | Forkhead Transcription Factors - metabolism | Immune Tolerance - immunology | HEK293 Cells | T-Lymphocytes, Regulatory - cytology | Female | Lymphocytes, Tumor-Infiltrating - metabolism | Colitis - immunology | Proto-Oncogene Proteins c-akt - metabolism | Lymphocytes, Tumor-Infiltrating - cytology | Signal Transduction | Cell Survival | Mice, Inbred C57BL | Homeostasis - immunology | PTEN Phosphohydrolase - metabolism | Semaphorins - metabolism | Immunological Synapses | Animals | Neoplasms - immunology | Mice | Forkhead Box Protein O3 | Neoplasms - pathology | Neuropilin-1 - deficiency | Lymphocytes, Tumor-Infiltrating - immunology | Immunosuppression | Semaphorins | Homeostasis | Physiological aspects | Research | T cells | Properties | Proteins | Immunology | Lymphocytes | Rodents | Melanoma | Kinases | Autoimmune diseases | Laboratory animals | Vascular endothelial growth factor | Cell adhesion & migration
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7. Neuropilin-1 (NRP-1) and magnetic nanoparticles, a potential combination for diagnosis and therapy of gliomas
by Chen, Lukui and Zhang, Guilong and Shi, Yan and Qiu, Rong and Khan, Ahsan Ali
Current Pharmaceutical Design, ISSN 1381-6128, 10/2015, Volume 21, Issue 37, pp. 5434 - 5449
In this review, Neuropilin-1 (NRP-1) has been focused as a novel molecular target for potential treatment of gliomas. The properties of NRP-1 were described... 
Magnetic nanoparticle | Neuropilin-1 | Glioma stem cell | Glioma | Gene therapy | Trafficking | IRON-OXIDE NANOPARTICLES | ANTIBODY TARGETING NEUROPILIN-1 | ENDOTHELIAL-GROWTH-FACTOR | PANCREATIC-CANCER | gene therapy | BLOOD-BRAIN-BARRIER | BREAST-CANCER CELLS | magnetic nanoparticle | glioma stem cell | IN-VIVO | glioma | PHARMACOLOGY & PHARMACY | SMOOTH-MUSCLE-CELLS | trafficking | TUMOR-GROWTH | HIGH-GRADE GLIOMA | Glioma - diagnosis | Neuropilin-1 - metabolism | Brain Neoplasms - diagnosis | Humans | Magnetite Nanoparticles - administration & dosage | Protein Transport - physiology | Brain Neoplasms - drug therapy | Brain Neoplasms - metabolism | Glioma - metabolism | Neuropilin-1 - chemistry | Magnetite Nanoparticles - chemistry | Animals | Signal Transduction - physiology | Neuropilin-1 - administration & dosage | Glioma - drug therapy
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8. Full Text An Unexpected Role of Semaphorin3A–Neuropilin-1 Signaling in Lymphatic Vessel Maturation and Valve Formation
by Jurisic, Giorgia and Maby-El Hajjami, Hélène and Karaman, Sinem and Ochsenbein, Alexandra M and Alitalo, Annamari and Siddiqui, Shoib S and Ochoa Pereira, Carlos and Petrova, Tatiana V and Detmar, Michael
Circulation Research, ISSN 0009-7330, 08/2012, Volume 111, Issue 4, pp. 426 - 436
RATIONALE:Lymphatic vasculature plays important roles in tissue fluid homeostasis maintenance and in the pathology of human diseases. Yet, the molecular... 
development | lymphatic valve | neuropilin-1 | lymphatic vessels | peri | microarrays | semaphorin 3A | CALL ALGORITHMS | CARDIAC & CARDIOVASCULAR SYSTEMS | pericytes | VEGF | SEMAPHORIN | ENDOTHELIAL-CELLS | LYMPHANGIOGENESIS | PERIPHERAL VASCULAR DISEASE | MICE | HEMATOLOGY | EXPRESSION | PERIPHERAL-NERVE PROJECTION | BLOOD | Neuropilin-1 - genetics | Antibodies, Neutralizing - administration & dosage | Oligonucleotide Array Sequence Analysis | Neuropilin-1 - metabolism | Humans | Vascular Endothelial Growth Factor A - metabolism | Semaphorin-3A - metabolism | Lymphatic Vessels - metabolism | Lymphangiogenesis | Myocytes, Smooth Muscle - metabolism | Neuropilin-1 - immunology | Semaphorin-3A - genetics | Lymphatic Vessels - embryology | Signal Transduction | Endothelial Cells - metabolism | Mice, Inbred C57BL | Pericytes - metabolism | Cells, Cultured | Gene Expression Profiling - methods | Cell Separation - methods | Gestational Age | Cell Lineage | Animals | Lymphatic Vessels - pathology | Mice | Cell Movement | Neuropilin-1 | Lymphatic vessels | Semaphorin 3A
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9. Full Text Semaphorin3A, Neuropilin-1, and PlexinA1 Are Required for Lymphatic Valve Formation
by Bouvrée, Karine and Brunet, Isabelle and del Toro, Raquel and Gordon, Emma and Prahst, Claudia and Cristofaro, Brunella and Mathivet, Thomas and Xu, Yunling and Soueid, Jihane and Fortuna, Vitor and Miura, Nayoki and Aigrot, Marie-Stéphane and Maden, Charlotte H and Ruhrberg, Christiana and Thomas, Jean Léon and Eichmann, Anne
Circulation Research, ISSN 0009-7330, 08/2012, Volume 111, Issue 4, pp. 437 - 445
RATIONALE:The lymphatic vasculature plays a major role in fluid homeostasis, absorption of dietary lipids, and immune surveillance. Fluid transport depends on... 
lymphatic vessel | development | vascular biology | vascular smooth muscle | valve | guidance | CARDIAC & CARDIOVASCULAR SYSTEMS | VEGF | SEMA3A | AXON GUIDANCE | ARTERIAL DIFFERENTIATION | VESSELS | PATTERN | ENDOTHELIAL-CELLS | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | Neuropilin-1 - genetics | Antibodies, Neutralizing - administration & dosage | Neuropilin-1 - metabolism | Humans | Nerve Tissue Proteins - deficiency | Semaphorin-3A - metabolism | RNA, Messenger - metabolism | Morphogenesis | Lymphatic Vessels - metabolism | Semaphorin-3A - deficiency | Gene Expression Regulation, Developmental | Neuropilin-1 - immunology | Semaphorin-3A - genetics | Animals, Newborn | Lymphatic Vessels - embryology | Endothelial Cells - metabolism | Bacterial Proteins - genetics | Cells, Cultured | Receptors, Cell Surface - metabolism | Genotype | Mice, Transgenic | Vascular Endothelial Growth Factor Receptor-3 - metabolism | Gestational Age | Nerve Tissue Proteins - genetics | Mice, Knockout | Nerve Tissue Proteins - metabolism | Phenotype | Animals | Receptors, Cell Surface - deficiency | Bacterial Proteins - metabolism | Luminescent Proteins - genetics | Mice | Neuropilin-1 - deficiency | Vascular Endothelial Growth Factor Receptor-3 - genetics | Luminescent Proteins - metabolism | Receptors, Cell Surface - genetics
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10. Full Text Autocrine VEGF-VEGFR2-Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth
by Hamerlik, Petra and Lathia, Justin D and Rasmussen, Rikke and Wu, Qiulian and Bartkova, Jirina and Lee, MyungHee and Moudry, Pavel and Bartek, Jiri and Fischer, Walter and Lukas, Jiri and Rich, Jeremy N and Bartek, Jiri
Journal of Experimental Medicine, ISSN 0022-1007, 03/2012, Volume 209, Issue 3, pp. 507 - 520
Although vascular endothelial growth factor (VEGF) receptor 2 (VEGFR2) is traditionally regarded as an endothelial cell protein, evidence suggests that VEGFRs... 
MEDICINE, RESEARCH & EXPERIMENTAL | GLIOBLASTOMA-MULTIFORME | RECURRENT GLIOBLASTOMA | ENDOTHELIAL-CELLS | BEVACIZUMAB PLUS IRINOTECAN | MALIGNANT GLIOMAS | VASCULAR NICHE | IMMUNOLOGY | IONIZING-RADIATION | UP-REGULATION | HIGH-GRADE GLIOMA | BRAIN-TUMORS | Neuropilin-1 - genetics | Autocrine Communication | RNA, Small Interfering - genetics | Cell Proliferation | Endosomes - physiology | Cell Survival | Humans | Neovascularization, Pathologic | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Neuropilin-1 - antagonists & inhibitors | Bevacizumab | Vascular Endothelial Growth Factor Receptor-2 - genetics | Glioblastoma - therapy | Neuropilin-1 - physiology | Vascular Endothelial Growth Factor Receptor-2 - antagonists & inhibitors | Antibodies, Monoclonal, Humanized - pharmacology | Glioblastoma - pathology | Neoplastic Stem Cells - pathology | Vascular Endothelial Growth Factor Receptor-2 - physiology | In Vitro Techniques | Glioblastoma - blood supply | Glioblastoma - physiopathology | Vascular Endothelial Growth Factor A - physiology | Neoplastic Stem Cells - physiology | 307
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11. Full Text Synergistic binding of vascular endothelial growth factor-a and its receptors to heparin selectively modulates complex affinity
by Teran, Madelane and Nugent, Matthew A
Journal of Biological Chemistry, ISSN 0021-9258, 06/2015, Volume 290, Issue 26, pp. 16451 - 16462
Background: Vascular endothelial growth factor (VEGF) requires heparin-like molecules for full activity. Results: VEGF, VEGF receptor-2, and neuropilin-1... 
ISOFORMS | TYROSINE KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | heparin-binding protein | neuropilin-1 | vascular endothelial growth factor (VEGF) | EXTRACELLULAR DOMAIN | surface plasmon resonance (SPR) | VEGF receptor | PATHOLOGICAL ANGIOGENESIS | TUMOR ANGIOGENESIS | MICE LACKING | heparin | heparan sulfate | SULFATE | SEMAPHORIN-III | MITOGENIC ACTIVITY | Endothelial Cells - chemistry | Neuropilin-1 - genetics | Heparin - metabolism | Signal Transduction | Endothelial Cells - metabolism | Neuropilin-1 - metabolism | Humans | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Vascular Endothelial Growth Factor Receptor-1 - metabolism | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - genetics | Vascular Endothelial Growth Factor Receptor-1 - chemistry | Vascular Endothelial Growth Factor Receptor-2 - genetics | Vascular Endothelial Growth Factor A - chemistry | Neuropilin-1 - chemistry | Vascular Endothelial Growth Factor Receptor-2 - chemistry | Animals | Heparan Sulfate Proteoglycans - metabolism | Protein Binding | Mice | Kinetics | Vascular Endothelial Growth Factor Receptor-1 - genetics | Glycobiology and Extracellular Matrices
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12. SPECT imaging of neuropilin receptor type-1 expression with 131 I-labeled monoclonal antibody
by Dou, Xiaofeng and Yan, Jianghua and Zhang, Yafei and Liu, Peng and Jiang, Yizhen and Lv, Sha and Zeng, Fanwei and Chen, Xiaoli and Wang, Shengyu and Zhang, Haipeng and Wu, Hua and Zhang, Hong and Ouyang, Lin and Su, Xinhui
International Journal of Oncology, ISSN 1019-6439, 09/2016, Volume 49, Issue 3, pp. 961 - 970
Neuropilin-1 | I | Monoclonal antibody | SPECT
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13. Full Text VEGF-A/Neuropilin 1 Pathway Confers Cancer Stemness via Activating Wnt/β-Catenin Axis in Breast Cancer Cells
by Zhang, Lansheng and Wang, Hongmei and Li, Caihong and Zhao, Yang and Wu, Langjie and Du, Xiuping and Han, Zhengxiang
Cellular Physiology and Biochemistry, ISSN 1015-8987, 12/2017, Volume 44, Issue 3, pp. 1251 - 1262
Background/Aims: Targeting cancer stem cells (CSCs) is emerging as a promising method for cancer treatment. We previously indicated that knockdown of... 
Original Paper | Nrp-1 VEGF-A Wnt/β-catenin CSCs breast cancer doxorubicin | INDUCED VASCULOGENESIS | PHYSIOLOGY | NEUROPILIN-1 | BONE METASTASIS | SUPPRESSES | PROLIFERATION | GENERATION | Nrp-1 VEGF-A Wnt/beta-catenin CSCs breast cancer doxorubicin | PROGRESSION | ENDOTHELIAL GROWTH-FACTOR | CELL BIOLOGY | Human Umbilical Vein Endothelial Cells | Neuropilin-1 - genetics | Wnt3A Protein - metabolism | Neoplastic Stem Cells - cytology | Neuropilin-1 - metabolism | Coculture Techniques | Humans | Transplantation, Heterologous | Vascular Endothelial Growth Factor A - metabolism | Spheroids, Cellular - cytology | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Vascular Endothelial Growth Factor A - genetics | Neuropilin-1 - antagonists & inhibitors | Breast Neoplasms - metabolism | MCF-7 Cells | Neoplastic Stem Cells - metabolism | RNA Interference | Female | Real-Time Polymerase Chain Reaction | Wnt3A Protein - genetics | Spheroids, Cellular - metabolism | beta Catenin - metabolism | Disease Progression | Doxorubicin - toxicity | beta Catenin - genetics | Phenotype | Animals | Wnt Signaling Pathway - drug effects | Breast Neoplasms - pathology | Mice, Nude | Cell Line, Tumor | Mice | Neovascularization, Physiologic | Cell Movement | Drug Resistance, Neoplasm - drug effects | RNA, Small Interfering - metabolism | Nrp-1 | VEGF-A | Wnt/β-catenin CSCs breast cancer doxorubicin
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14. Full Text Neuropilin-1 regulates platelet-derived growth factor receptor signalling in mesenchymal stem cells
by Ball, Stephen G and Bayley, Christopher and Shuttleworth, C. Adrian and Kielty, Cay M
Biochemical Journal, ISSN 0264-6021, 04/2010, Volume 427, Issue 1, pp. 29 - 40
Using human MSCs (mesenchymal stem cells) lacking VEGF (vascular endothelial growth factor) receptors, we show that the pro-angiogenic receptor neuropilin-1... 
Mesenchymal stem cell | Neuropilin-1 | Co-localization | Migration | Network assembly | Platelet-derived growth factor receptor | VASCULAR DEVELOPMENT | mesenchymal stem cell | ANGIOGENESIS | VEGF | BIOCHEMISTRY & MOLECULAR BIOLOGY | neuropilin-1 | AUTOCRINE | ENDOTHELIAL-CELLS | DISEASE | migration | platelet-derived growth factor receptor | PDGF-ALPHA-RECEPTOR | network assembly | co-localization | BINDING | EXPRESSION | Neuropilin-1 - genetics | Phosphorylation | Cell Proliferation | Immunoprecipitation | Neuropilin-1 - metabolism | Humans | Vascular Endothelial Growth Factor A - metabolism | RNA, Messenger - metabolism | Receptor, Platelet-Derived Growth Factor beta - genetics | Vascular Endothelial Growth Factor A - genetics | Platelet-Derived Growth Factor - genetics | Immunoenzyme Techniques | Neuropilin-1 - antagonists & inhibitors | Receptor, Platelet-Derived Growth Factor beta - metabolism | Receptor, Platelet-Derived Growth Factor alpha - metabolism | Proto-Oncogene Proteins c-sis | RNA, Messenger - genetics | RNA, Small Interfering - pharmacology | Mesenchymal Stromal Cells - metabolism | Chorioallantoic Membrane - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Platelet-Derived Growth Factor - metabolism | Animals | Receptor, Platelet-Derived Growth Factor alpha - genetics | Chickens | Cell Movement | NA, numerical aperture | NRP-1, neuropilin-1 | p-, phosphorylated | VEGF, vascular endothelial growth factor | RT, reverse transcription | DAPI, 4′,6-diamidino-2-phenylindole | siRNA, small interfering RNA | PDGFR, PDGF receptor | ES, embryonic stem | VEGFR, VEGF receptor | HGF, hepatocyte growth factor | MSC, mesenchymal stem cell | PDGF, platelet-derived growth factor | HUVEC, human umbilical vein endothelial cell | CAM, chorioallantoic membrane
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