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Nature Neuroscience, ISSN 1097-6256, 02/2013, Volume 16, Issue 2, pp. 183 - 192
A major unresolved issue in treating pain is the paradoxical hyperalgesia produced by the gold-standard analgesic morphine and other opiates. We found that... 
LAMINA-I NEURONS | NEUROTROPHIC FACTOR | P2X RECEPTORS | DOWN-REGULATION | OPIOID-RECEPTOR GENE | SPINAL-CORD-INJURY | UNDERLYING NEUROPATHIC PAIN | ALTERED CHLORIDE HOMEOSTASIS | NERVE INJURY | NEUROSCIENCES | INDUCED ABNORMAL PAIN | Brain-Derived Neurotrophic Factor - genetics | Biophysical Phenomena - drug effects | Motor Activity - drug effects | Male | Ribosome Inactivating Proteins, Type 1 - pharmacology | Touch | CD11b Antigen - genetics | Microglia - physiology | Time Factors | Chlorides - metabolism | Pain Threshold - drug effects | Biophysical Phenomena - genetics | Vocalization, Animal - drug effects | Brain-Derived Neurotrophic Factor - metabolism | Homeostasis - drug effects | Protein Synthesis Inhibitors - pharmacology | Spinal Cord - cytology | Neurons - drug effects | Membrane Potentials - drug effects | Hot Temperature - adverse effects | Microglia - drug effects | Mice, Inbred C57BL | Rats | Mice, Transgenic | Signal Transduction - genetics | Down-Regulation - drug effects | Rats, Sprague-Dawley | Symporters - metabolism | Gene Expression Regulation - drug effects | Narcotics - administration & dosage | Patch-Clamp Techniques | Rotarod Performance Test | Animals | Hyperalgesia - drug therapy | Signal Transduction - drug effects | Naloxone - pharmacology | Narcotic Antagonists - pharmacology | Mice | CD11b Antigen - metabolism | Receptors, Purinergic P2X4 - metabolism | Morphine - administration & dosage | Receptors, Purinergic P2X4 - genetics | Ion Channel Gating - drug effects
Journal Article
Neurogastroenterology & Motility, ISSN 1350-1925, 12/2011, Volume 23, Issue 12, pp. 1132 - 1139
Background  The probiotic Bifidobacterium longum NCC3001 normalizes anxiety‐like behavior and hippocampal brain derived neurotrophic factor (BDNF) in mice with... 
gut–brain axis | behavior | vagus | brain‐derived neurotrophic factor | probiotics | Probiotics | Brain-derived neurotrophic factor | Vagus | Behavior | Gut-brain axis | ACTIVATION | NEUROTROPHIC FACTOR | MOUSE | NEUROSCIENCES | CLINICAL NEUROLOGY | INFLAMMATION | NEURONS | MICE | INFECTION | brain-derived neurotrophic factor | DYSFUNCTION | GASTROENTEROLOGY & HEPATOLOGY | EXPRESSION | gut-brain axis | Brain-Derived Neurotrophic Factor - genetics | Enteric Nervous System - cytology | Enteric Nervous System - drug effects | Humans | Male | Neurons - cytology | Anxiety - drug therapy | Brain - metabolism | Feces - microbiology | Colitis - chemically induced | Bifidobacterium - metabolism | Neurons - physiology | Placebos | Behavior, Animal - drug effects | Brain-Derived Neurotrophic Factor - metabolism | Colitis - drug therapy | Anti-Anxiety Agents - therapeutic use | Gastrointestinal Tract - innervation | Neurons - drug effects | Dextran Sulfate - pharmacology | Cell Line | Anxiety - physiopathology | Gastrointestinal Tract - microbiology | Behavior, Animal - physiology | Gastrointestinal Tract - drug effects | Probiotics - pharmacology | Vagotomy | Vagus Nerve - physiology | Animals | Colitis - physiopathology | Probiotics - therapeutic use | Mice | Enteric Nervous System - physiology | Vagus Nerve - anatomy & histology | Dextran | Neurosciences | Messenger RNA | Metabolites | Neurons | Analysis | Colitis | Universities and colleges | Sulfates | Antianxiety agents | Drinking water | Microelectrodes | vagotomy | Central nervous system | Excitability | Inflammation | Gene expression | Neurotrophic factors | Anxiolytics | Enteric nervous system | Lymphocytes B | Anxiety | Peroxidase | Vagus nerve | Digestive tract | sodium sulfate | Hippocampus | Communication
Journal Article
Endocrinology, ISSN 0013-7227, 02/2016, Volume 157, Issue 2, pp. 774 - 787
Severe thyroid hormone (TH) deficiency during critical phases of brain development results in irreversible neurological and cognitive impairments. The... 
PROPYLTHIOURACIL PTU | MESSENGER-RNA | GYRUS IN-VIVO | ENDOCRINOLOGY & METABOLISM | NEUROTROPHIC FACTOR BDNF | GESTATIONAL MATERNAL HYPOTHYROXINEMIA | LONG-TERM POTENTIATION | DENTATE GYRUS | SYNAPTIC PLASTICITY | INCREASED AUTISM RISK | NERVE GROWTH-FACTOR | TOR Serine-Threonine Kinases - metabolism | Cytoskeletal Proteins - genetics | Rats, Long-Evans | Congenital Hypothyroidism - chemically induced | Neuronal Plasticity - drug effects | Male | Neuronal Plasticity - physiology | TOR Serine-Threonine Kinases - genetics | Triiodothyronine - drug effects | Behavior, Animal - drug effects | Brain-Derived Neurotrophic Factor - metabolism | Kruppel-Like Transcription Factors - drug effects | TOR Serine-Threonine Kinases - drug effects | Disease Models, Animal | Hippocampus - embryology | Maze Learning - physiology | Propylthiouracil - toxicity | Rats | Behavior, Animal - physiology | Nerve Growth Factor - genetics | Antithyroid Agents - toxicity | Nerve Tissue Proteins - drug effects | Thyroxine - metabolism | Neurotrophin 3 - drug effects | Kruppel-Like Transcription Factors - genetics | Brain-Derived Neurotrophic Factor - genetics | Neurotrophin 3 - genetics | Early Growth Response Protein 1 - drug effects | Brain-Derived Neurotrophic Factor - drug effects | Triiodothyronine - metabolism | Kruppel-Like Transcription Factors - metabolism | Early Growth Response Protein 1 - genetics | Cytoskeletal Proteins - metabolism | Female | Cytoskeletal Proteins - drug effects | Nerve Growth Factor - drug effects | Congenital Hypothyroidism - embryology | Severity of Illness Index | Nerve Growth Factor - metabolism | Conditioning (Psychology) - drug effects | Conditioning (Psychology) - physiology | Triiodothyronine - deficiency | Congenital Hypothyroidism - metabolism | Maze Learning - drug effects | Nerve Tissue Proteins - genetics | Prenatal Exposure Delayed Effects - metabolism | Nerve Tissue Proteins - metabolism | Pregnancy | Thyroxine - drug effects | Fear | Hippocampus - metabolism | Animals | Neurotrophin 3 - metabolism | Thyroxine - deficiency | Early Growth Response Protein 1 - metabolism | Prenatal Exposure Delayed Effects - chemically induced | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
Journal Article
Glia, ISSN 0894-1491, 12/2006, Volume 54, Issue 8, pp. 840 - 849
We have investigated the phenotypic and bioassay characteristics of bone marrow mesenchymal stromal cells (MSCs) differentiated along a Schwann cell lineage... 
differentiation | glial growth factor | mesenchymal stem cells | neuronal co‐culture | Schwann cells | Glial growth factor | Neuronal co-culture | Differentiation | Mesenchymal stem cells | PROGENITOR CELLS | MOUSE-BRAIN | PERIPHERAL-NERVE REGENERATION | ADULT SENSORY NEURONS | NEURAL STEM | SPINAL-CORD | NEUROSCIENCES | NESTIN | IN-VITRO | HUMAN BONE-MARROW | neuronal co-culture | MARROW STROMAL CELLS | Neurites - physiology | Coculture Techniques | Alkaline Phosphatase - metabolism | Rats, Inbred Lew | Cell Communication - physiology | Glial Fibrillary Acidic Protein - metabolism | Cell Lineage - drug effects | Schwann Cells - cytology | Mesenchymal Stromal Cells - cytology | Neurites - ultrastructure | Glial Cell Line-Derived Neurotrophic Factor - pharmacology | Up-Regulation - physiology | Stromal Cells - drug effects | Bone Marrow Cells - drug effects | Cell Differentiation - physiology | Receptor, Nerve Growth Factor - metabolism | Animals, Newborn | Biomarkers - metabolism | Mesenchymal Stromal Cells - drug effects | Bone Marrow Cells - cytology | Stromal Cells - metabolism | Cells, Cultured | Mesenchymal Stromal Cells - metabolism | Rats | S100 Proteins - metabolism | Schwann Cells - metabolism | Cell Lineage - physiology | Cell Shape - drug effects | Up-Regulation - drug effects | Phenotype | Animals | Cell Differentiation - drug effects | Cell Shape - physiology | Bone Marrow Cells - metabolism | Stromal Cells - cytology | Cell Lineage/drug effects/physiology | Schwann Cells/cytology/metabolism | Cells; Cultured | S100 Proteins/metabolism | Cell Differentiation/drug effects/physiology | Neurites/physiology/ultrastructure | Cell Shape/drug effects/physiology | Animals; Newborn | Biological Markers/metabolism | Stromal Cells/cytology/drug effects/metabolism | Up-Regulation/drug effects/physiology | Cell Communication/physiology | Glial Fibrillary Acidic Protein/metabolism | Mesenchymal Stem Cells/cytology/drug effects/metabolism | Receptor; Nerve Growth Factor/metabolism | Glial Cell Line-Derived Neurotrophic Factor/pharmacology | Bone Marrow Cells/cytology/drug effects/metabolism | Alkaline Phosphatase/metabolism | Rats; Inbred Lew
Journal Article
Ophthalmology, ISSN 0161-6420, 04/2019, Volume 126, Issue 4, pp. 540 - 549
Purpose: To test the effects of an encapsulated cell-based delivery of a neuroprotective agent, ciliary neurotrophic factor (CNTF), on progression of macular... 
OPHTHALMOLOGY | PREVALENCE | LAYER | PHOTORECEPTORS | Clinical trials | Ciliary neurotrophic factor | Telangiectasis
Journal Article