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1. Full Text Mortality Attributable to Smoking Among HIV-1—Infected Individuals: A Nationwide, Population-Based Cohort Study
by Marie Helleberg and Shoaib Afzal and Gitte Kronborg and Carsten S. Larsen and Gitte Pedersen and Court Pedersen and Jan Gerstoft and Børge G. Nordestgaard and Niels Obel
Clinical Infectious Diseases, ISSN 1058-4838, 3/2013, Volume 56, Issue 5, pp. 727 - 734
Background. We assessed mortality attributable to smoking among patients with human immunodeficiency virus (HIV). Methods. We estimated mortality rates (MRs),... 
HIV/AIDS | Smoking cessation | HIV | Mortality | Tobacco smoking | Cohort studies | Death | AIDS | Cigarette smoking | Population control | Disease risks | mortality | population attributable risk | non-AIDS related mortality | smoking | INFECTIOUS DISEASES | MICROBIOLOGY | ANTIRETROVIRAL THERAPY | DEATH | IMMUNOLOGY | HIV-INFECTED PATIENTS | CIGARETTE-SMOKING | IMPACT | MORBIDITY | ERA | LIFE | HIV-1 - pathogenicity | Smoking - mortality | Humans | Middle Aged | Risk Factors | Kaplan-Meier Estimate | Male | Cause of Death | Life Expectancy | Denmark - epidemiology | Adult | Female | HIV Infections - mortality | Cohort Studies | HIV patients | Health aspects | Risk factors | Smoking
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2. Full Text Inflammation-Related Morbidity and Mortality Among HIV-Positive Adults: How Extensive Is It?
by Hart, Brian B and Nordell, Anna D and Okulicz, Jason F and Palfreeman, Adrian and Horban, Andrzej and Kedem, Eynat and Neuhaus, Jacqueline and Jacobs, David R and Duprez, Daniel A and Neaton, James D and ESPRIT Grp and INSIGHT SMART Grp and INSIGHT SMART and ESPRIT Groups
JAIDS Journal of Acquired Immune Deficiency Syndromes, ISSN 1525-4135, 01/2018, Volume 77, Issue 1, pp. 1 - 7
OBJECTIVE:To determine the rate of grade 4, potentially life-threatening events not attributable to AIDS, cardiovascular disease (CVD), or non-AIDS cancer... 
grade 4 events | serious non-AIDS | C-REACTIVE PROTEIN | INFECTIOUS DISEASES | EVENTS | MYOCARDIAL-INFARCTION | D-dimer | AIDS | RISK | DEATH | IMMUNOLOGY | INCIDENT CARDIOVASCULAR-DISEASE | interleukin-6 | COAGULATION BIOMARKERS | CLINICAL-TRIALS | INFECTION | Biomarkers - metabolism | HIV Seropositivity | Fibrin Fibrinogen Degradation Products - metabolism | HIV Infections - epidemiology | Humans | Middle Aged | Proportional Hazards Models | Male | HIV - immunology | Inflammation | Morbidity | Antiretroviral Therapy, Highly Active | Young Adult | HIV Infections - immunology | Blood Coagulation | Adult | Female | HIV Infections - drug therapy | HIV Infections - mortality | Aged | Interleukin-6 - metabolism | Cohort Studies | Grade 4 events
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3. Full Text High cancer-related mortality in an urban, predominantly African-American, HIV-infected population
by Riedel, David J and Mwangi, Evelyn Ivy W and Fantry, Lori E and Alexander, Carla and Hossain, Mian B and Pauza, C. David and Redfield, Robert R and Gilliam, Bruce L
AIDS, ISSN 0269-9370, 04/2013, Volume 27, Issue 7, pp. 1109 - 1117
Objective: To determine mortality associated with a new cancer diagnosis in an urban, predominantly African-American, HIV-infected population. Design:... 
AIDS-defining cancer | Urban | HIV | Non-AIDS-defining cancer | Mortality | AIDS | Malignancy | Cancer | UNITED-STATES | SURVIVAL | INFECTIOUS DISEASES | malignancy | RISK | non-AIDS-defining cancer | IMMUNOLOGY | HUMAN-IMMUNODEFICIENCY-VIRUS | GENERAL-POPULATION | VIROLOGY | urban | ERA | ACTIVE ANTIRETROVIRAL THERAPY | mortality | cancer | PEOPLE | SOCIOECONOMIC-STATUS | HIV-1 - pathogenicity | Follow-Up Studies | Humans | Middle Aged | Male | Baltimore - epidemiology | Urban Population | Viral Load | Incidence | Anti-HIV Agents - administration & dosage | Neoplasms - virology | Neoplasms - chemically induced | Adult | Female | HIV Infections - mortality | Retrospective Studies | Substance-Related Disorders - mortality | Maryland - epidemiology | Anti-HIV Agents - adverse effects | Risk Factors | Proportional Hazards Models | Neoplasms - mortality | European Continental Ancestry Group - statistics & numerical data | Disease Progression | African Americans - statistics & numerical data | Adolescent | Aged | non-AIDS defining cancer
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4. Full Text Poor CD4 response despite viral suppression is associated with increased non-AIDS-related mortality among HIV patients and their parents
by Helleberg, Marie and Kronborg, Gitte and Larsen, Carsten S and Pedersen, Gitte and Pedersen, Court and Obel, Niels and Gerstoft, Jan
AIDS, ISSN 0269-9370, 03/2013, Volume 27, Issue 6, pp. 1021 - 1026
Introduction: Poor CD4 response to antiretroviral treatment (HAART) is associated with increased mortality. We analyzed the impact of CD4 increase on... 
Non-AIDS-related death | HIV | Mortality | CD4 recovery | INFECTIOUS DISEASES | RISK | IMMUNOLOGY | HUMAN-IMMUNODEFICIENCY-VIRUS | VIROLOGICAL RESPONSES | RENAL-TRANSPLANT RECIPIENTS | RECOVERY | POLYMORPHISMS | VIROLOGY | ACTIVE ANTIRETROVIRAL THERAPY | mortality | non-AIDS-related death | INFECTED PATIENTS | COHORT | T-CELLS | Humans | Parents | Male | Acquired Immunodeficiency Syndrome - drug therapy | Viral Load | Incidence | Anti-HIV Agents - administration & dosage | CD4-Positive T-Lymphocytes - immunology | Acquired Immunodeficiency Syndrome - immunology | Survival Analysis | Acquired Immunodeficiency Syndrome - mortality | Denmark - epidemiology | Adult | Female | Acquired Immunodeficiency Syndrome - virology
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5. Full Text Smoking and life expectancy among HIV-infected individuals on antiretroviral therapy in Europe and North America
by Helleberg, Marie and May, Margaret T and Ingle, Suzanne M and Dabis, Francois and Reiss, Peter and Fätkenheuer, Gerd and Costagliola, Dominique and d’Arminio, Antonella and Cavassini, Matthias and Smith, Colette and Justice, Amy C and Gill, John and Sterne, Jonathan A.C and Obel, Niels
AIDS, ISSN 0269-9370, 01/2015, Volume 29, Issue 2, pp. 221 - 229
Cardiovascular disease and non-AIDS malignancies have become major causes of death among HIV-infected individuals. The relative impact of lifestyle and... 
Non-AIDS related mortality | Tobacco | Life expectancy | HIV | Mortality | Smoking | INFECTIOUS DISEASES | AIDS | DEATH | IMMUNOLOGY | non-AIDS related mortality | life expectancy | CIGARETTE-SMOKING | GENERAL-POPULATION | IMPACT | VIROLOGY | MORBIDITY | ERA | smoking | mortality | tobacco | PEOPLE | BENEFITS | Europe | Humans | Middle Aged | Male | CD4 Lymphocyte Count | Life Expectancy - trends | North America | Antiretroviral Therapy, Highly Active | Smoking - epidemiology | Adult | Female | HIV Infections - drug therapy | HIV Infections - mortality | Cohort Studies | Epidemiology and Social
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6. Full Text HIV-induced immunodeficiency and mortality from AIDS-defining and non-AIDS-defining malignancies
by D'Arminio Monforte, Antonella and Abrams, Donald and Pradier, Christian and Weber, Rainer and Reiss, Peter and Bonnet, Fabrice and Kirk, Ole and Law, Matthew and de Wit, Stephane and Friis-Møller, Nina and Phillips, Anew N and Sabin, Caroline A and Lundgren, Jens D and Collins, S and Loeliger, E and Tressler, R and Weller, I and Friis-Møller, N and Worm, S. W and Sabin, C. A and Sjøl, A and Lundgren, J. D and Sawitz, A and Rickenbach, M and Pezzotti, P and Krum, E and Gras, L and Balestre, E and Sundström, A and Poll, B and Fontas, E and Torres, F and Petoumenos, K and Kjaer, J and de Wolf, F and Zaheri, S and Bronsveld, W and Hillebrand-Haverkort, M. E and Prins, J. M and Bos, J. C and Eeftinck Schattenkerk, J. K. M and Geerlings, S. E and Godfried, M. H and Lange, J. M. A and van der Meer, J. T. M and Nellen, F. J. B and van der Poll, T and van der Valk, M and van Vugt, M and Wit, F. W. M. N and Data Collect Adverse Events and Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) Study Group
AIDS (London, England), ISSN 0269-9370, 2008, Volume 22, Issue 16, pp. 2143 - 2153
OBJECTIVE: To evaluate deaths from AIDS-defining malignancies (ADM) and non-AIDS-defining malignancies (nADM) in the D:A:D Study and to investigate the... 
D:A:D study | Non-AIDS-defining malignancies | AIDS-defining malignancies | HIV infection | Mortality | UNITED-STATES | CELLS | INFECTIOUS DISEASES | VIRUS | DEATH | IMMUNOLOGY | LIVER-DISEASE | non-AIDS-defining malignancies | VIROLOGY | HEPATITIS | ERA | ACTIVE ANTIRETROVIRAL THERAPY | mortality | CANCER-RISK | INFECTED PATIENTS | Age Factors | Drug Administration Schedule | Humans | Middle Aged | Neoplasms - mortality | Male | CD4 Lymphocyte Count | Lymphoma, AIDS-Related - immunology | Anti-HIV Agents - administration & dosage | Young Adult | HIV Infections - immunology | Lymphoma, AIDS-Related - mortality | Neoplasms - virology | Epidemiologic Methods | Neoplasms - immunology | HIV Infections - complications | Sex Factors | Adult | Female | HIV Infections - drug therapy | HIV Infections - mortality | Aged | Immunocompromised Host | Homosexuality, Male - statistics & numerical data
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7. Full Text Increased non-AIDS mortality among persons with AIDS-defining events after antiretroviral therapy initiation
by Pettit, April C and Giganti, Mark J and Ingle, Suzanne M and May, Margaret T and Shepherd, Bryan E and Gill, Michael J and Fätkenheuer, Gerd and Abgrall, Sophie and Saag, Michael S and del Amo, Julia and Justice, Amy C and Miro, Jose M and Cavasinni, Matthias and Dabis, François and Monforte, Antonella D and Reiss, Peter and Guest, Jodie and Moore, David and Shepherd, Leah and Obel, Niels and Crane, Heidi M and Smith, Colette and Teira, Ramon and Zangerle, Robert and Sterne, Jonathan A. C and Sterling, Timothy R and Antiretroviral Therapy Cohort and Antiretroviral Therapy Cohort Collaboration (ART-CC) investigators and for the Antiretroviral Therapy Cohort Collaboration (ART-CC) investigators
Journal of the International AIDS Society, ISSN 1758-2652, 2018, Volume 21, Issue 1, pp. 1 - n/a
HIV-1 infection leads to chronic inflammation and to an increased risk of non-AIDS mortality. Our objective was to determine whether AIDS-defining events... 
non‐AIDS mortality | Pneumocystis jiroveci pneumonia | non‐Hodgkin's lymphoma | marginal structural model | AIDS‐defining events | tuberculosis | non-AIDS mortality | AIDS-defining events | non-Hodgkin's lymphoma | INFECTIOUS DISEASES | RISK-FACTORS | COLLABORATIVE ANALYSIS | DEATH | IMMUNOLOGY | HUMAN-IMMUNODEFICIENCY-VIRUS | TRENDS | HIV-INFECTED PATIENTS | INDIVIDUALS | IMPACT | ERA | LIFE EXPECTANCY | Tuberculosis - mortality | Humans | Middle Aged | Adult | Anti-HIV Agents - therapeutic use | Female | Male | Lymphoma, Non-Hodgkin - mortality | Pneumonia, Pneumocystis - mortality | Acquired Immunodeficiency Syndrome - complications | Acquired Immunodeficiency Syndrome - drug therapy | Cohort Studies | Antiviral agents | Complications and side effects | Patient outcomes | AIDS (Disease) | Dosage and administration | Drug therapy | HIV infection | Medical research | Codes | Classification schemes | Funding | Mortality | Infections | Patients | Ethics | Disease transmission | Acquired immune deficiency syndrome--AIDS | Human immunodeficiency virus--HIV | Classification | Age | Mortalitat | Antiretrovirals | Malalts de sida | AIDS patients | Antiretroviral agents
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8. Full Text Increased risk of non-AIDS-related events in HIV subjects with persistent low CD4 counts despite cART in the CoRIS cohort
by Pacheco, Y.M and Jarrin, I and Rosado, I and Campins, A.A and Berenguer, J and Iribarren, J.A and Rivero, M and Muñoz-Medina, L and Bernal-Morell, E and Gutiérrez, F and Leal, M and CoRIS
Antiviral Research, ISSN 0166-3542, 05/2015, Volume 117, pp. 69 - 74
•We explored clinical complications of HIV subjects with persistent low CD4 despite virological suppression under cART.•The persistence of low CD4 despite... 
Low-CD4 restoration | Non-AIDS-defining malignancies | Mortality | Immunodeficiency | AIDS | Clinical complications | Non-AIDS-defining events | VIRAL SUPPRESSION | PARENTS | DEFINING MALIGNANCIES | LONG-TERM MORTALITY | CANCER | INDIVIDUALS | RECOVERY | VIROLOGY | PHARMACOLOGY & PHARMACY | INFECTED PATIENTS | COMBINATION ANTIRETROVIRAL THERAPY | Prospective Studies | HIV Infections - virology | Humans | Middle Aged | Risk Factors | Male | CD4 Lymphocyte Count | Viral Load | Antiretroviral Therapy, Highly Active | Young Adult | HIV Infections - immunology | Neoplasms - complications | Regression Analysis | Cardiovascular Diseases - complications | Time Factors | Spain - epidemiology | HIV Infections - complications | Cardiovascular Diseases - epidemiology | Adult | Female | HIV Infections - drug therapy | Aged | Neoplasms - epidemiology | Cohort Studies | HIV (Viruses) | Risk factors | AIDS (Disease)
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9. Full Text Cytomegalovirus coinfection is associated with an increased risk of severe non-AIDS-defining events in a large cohort of HIV-infected patients
by Lichtner, Miriam and Cicconi, Paola and Vita, Serena and Cozzi-Lepri, Alessandro and Galli, Massimo and Lo Caputo, Sergio and Saracino, Annalisa and De Luca, Andrea and Moioli, Mariacristina and Maggiolo, Franco and Marchetti, Giulia and Vullo, Vincenzo and Monforte, Antonella D'Arminio and ICONA Fdn Study and ICONA Foundation Study
Journal of Infectious Diseases, ISSN 0022-1899, 01/2015, Volume 211, Issue 2, pp. 178 - 186
Background. Chronic cytomegalovirus (CMV) infection has been associated with immunosenescence and immunoactivation in the general population. In human... 
mortality | cardiovascular/cerebrovascular events | CMV infection | severe non-AIDS-defining events | morbidity | HIV infection | INTIMA-MEDIA THICKNESS | INFECTIOUS DISEASES | SEROCONVERSION | IMMUNOGLOBULIN-G ANTIBODY | ATHEROSCLEROSIS | MICROBIOLOGY | ANTIRETROVIRAL THERAPY | IMMUNOLOGY | SEROPREVALENCE | HUMAN IMMUNODEFICIENCY VIRUS | INFLAMMATION | DISEASE PROGRESSION | AIDS-Related Opportunistic Infections - complications | AIDS-Related Opportunistic Infections - pathology | Prospective Studies | Cross-Sectional Studies | Immunoglobulin G - blood | Risk Assessment | AIDS-Related Opportunistic Infections - immunology | Humans | Male | Cytomegalovirus Infections - immunology | Antibodies, Viral - blood | AIDS-Related Opportunistic Infections - epidemiology | Cardiovascular Diseases - epidemiology | Adult | Female | Cerebrovascular Disorders - epidemiology | Cohort Studies
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10. Full Text Non-AIDS-related comorbidities in people living with HIV-1 aged 50 years and older: The AGING POSITIVE study
by Serrão, Rosário and Piñero, Carmela and Velez, Jorge and Coutinho, Daniel and Maltez, Fernando and Lino, Sara and Sarmento e Castro, Rui and Tavares, Ana Paula and Pacheco, Patrícia and Lopes, Maria João and Mansinho, Kamal and Miranda, Ana Cláudia and Neves, Isabel and Correia de Abreu, Ricardo and Almeida, Joana and Pássaro, Leonor
International Journal of Infectious Diseases, ISSN 1201-9712, 02/2019, Volume 79, pp. 94 - 100
•A high prevalence of non-AIDS-related comorbidities (NARC) was found in Portuguese HIV-infected patients ≥50 years old.•The most common NARC were metabolic,... 
HIV-1 infection | Aging | Non-AIDS comorbidities | MORTALITY | INFECTIOUS DISEASES | METABOLIC SYNDROME | RISK-FACTORS | EFFICACY | PREVALENCE | INDIVIDUALS | MORBIDITY | INFECTED PERSONS | OUTCOMES | BURDEN | Hypercholesterolemia | Comorbidity | Analysis | Anticholesteremic agents | HIV patients | Diabetes | HIV (Viruses) | HIV infection | Cardiovascular agents
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11. Full Text Relationship between current level of immunodeficiency and non‐acquired immunodeficiency syndrome‐defining malignancies
by Reekie, Joanne and Kosa, Csaba and Engsig, Frederik and Monforte, Antonella d'Arminio and Wiercinska‐Drapalo, Alicja and Domingo, Pere and Antunes, Francisco and Clumeck, Nathan and Kirk, Ole and Lundgren, Jens D and Mocroft, Amanda and EuroSIDA Study Grp and EuroSIDA Study Group and for the EuroSIDA Study Group
Cancer, ISSN 0008-543X, 11/2010, Volume 116, Issue 22, pp. 5306 - 5315
BACKGROUND: In the combined antiretroviral therapy (cART) era, non–acquired immunodeficiency syndrome (AIDS)‐defining malignancies account for more morbidity... 
immunodeficiency | HIV | CD4 count | virus‐related | non‐AIDS defining malignancy | non-AIDS defining malignancy | virus-related | UNITED-STATES | VIRUS-INFECTION | RISK-FACTORS | HAART ERA | HIV-INFECTED INDIVIDUALS | HEPATOCELLULAR-CARCINOMA | GENERAL-POPULATION | ONCOLOGY | ANAL CANCER | CANCER-RISK | COMBINATION ANTIRETROVIRAL THERAPY | Humans | Risk Factors | Male | CD4 Lymphocyte Count | Incidence | Neoplasms - complications | Neoplasms - immunology | Tumor Virus Infections - immunology | Adult | Female | Acquired Immunodeficiency Syndrome - complications | Tumor Virus Infections - epidemiology | Neoplasms - epidemiology | Antiviral agents | Usage | Prognosis | CD4 lymphocytes | Physiological aspects | Immunological deficiency syndromes | Drug therapy, Combination | Research | Health aspects | Lung cancer | Mortality | antiretroviral therapy | Immunodeficiency | Melanoma | Clinical trials | Malignancy | Hodgkin's disease | Morbidity | CD4 antigen
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