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Cancer Letters, ISSN 0304-3835, 12/2017, Volume 410, pp. 201 - 211
Journal Article
Current Topics in Medicinal Chemistry, ISSN 1568-0266, 06/2011, Volume 11, Issue 11, pp. 1340 - 1351
CK2 denotes a pleiotropic, constitutively active protein kinase whose abnormally high level in many cancer cells is held as an example of "non oncogene... 
PIM-1 | Non-oncogene addiction | Promiscuity Score | DYRK1A | CK2 | ERK-8 | Quinalizarin | HIPK2 | quinalizarin | CANCER-CELLS | CASEIN KINASE-2 | CHEMISTRY, MEDICINAL | ACID | 4,5,6,7-TETRABROMOBENZIMIDAZOLE | TRANSCRIPTION | non-oncogene addiction | POTENT INHIBITORS | ADDICTION | DERIVATIVES | SELECTIVITY | STRUCTURE-BASED DESIGN
Journal Article
Journal Article
Journal Article
CANCER DISCOVERY, ISSN 2159-8274, 07/2013, Volume 3, Issue 7, pp. 782 - 797
Although diacylglycerol kinase alpha (DGK alpha) has been linked to several signaling pathways related to cancer cell biology, it has been neglected as a... 
ACTIVATION | INHIBITION | METABOLISM | ONCOLOGY | PATHWAY | INSULIN-RESISTANCE | T-CELL ANERGY | ALPHA | NON-ONCOGENE ADDICTION | PHOSPHATIDIC-ACID | MODULATION
Journal Article
Cancer Research, ISSN 0008-5472, 12/2010, Volume 70, Issue 24, pp. 10288 - 10298
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 07/2018, Volume 61, Issue 14, pp. 6163 - 6177
Cancer cells rely on the chaperone heat shock protein 70 (Hsp70) for survival and proliferation. Recently, benzothiazole rhodacyanines have been shown to bind... 
INTERDOMAIN LINKER | CHEMISTRY, MEDICINAL | TARGETING HSP70 | SMALL-MOLECULE | GENETIC SCREENS | ADENOSINE-DERIVED INHIBITORS | CHAPERONE | MAMMALIAN-CELLS | DRUG TARGETS | CANCER-THERAPY | HEAT-SHOCK-PROTEIN | Index Medicus | breast cancer | non-oncogene addiction | chaperone | structure-activity relationships | proteostasis | allostery
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2011, Volume 108, Issue 45, pp. 18378 - 18383
Journal Article
Cancer Cell, ISSN 1535-6108, 11/2016, Volume 30, Issue 5, pp. 683 - 693
Journal Article
ACS Medicinal Chemistry Letters, ISSN 1948-5875, 07/2012, Volume 3, Issue 7, pp. 602 - 606
Accelerated proliferation of solid tumor and hematologic cancer cells is linked to accelerated transcription of rDNA by the RNA polymerase I (Pol I) enzyme to... 
CX-5461 | RNA polymerase I | rRNA | p53 | GROWTH-CONTROL | CHEMISTRY, MEDICINAL | TRANSCRIPTION | NON-ONCOGENE ADDICTION | RIBOSOME BIOGENESIS
Journal Article
CANCER SCIENCE, ISSN 1349-7006, 01/2018, Volume 109, pp. 786 - 786
Conference Proceeding
Journal Article
CANCER RESEARCH, ISSN 0008-5472, 06/2018, Volume 78, Issue 11, pp. 2939 - 2951
Although oncogenic activation of NF kappa B has been identified in various tumors, the NF kappa B-activating kinases (inhibitor of NF kappa B kinases, IKK)... 
ACTIVATION | INHIBITION | CARCINOGENESIS | ONCOLOGY | RAS | GENE-EXPRESSION | CELL-PROLIFERATION | IKK-ALPHA | CANCER | MOUSE MODELS | BETA | Adenocarcinoma | Translocation | Hsp90 protein | Cell survival | Therapeutic applications | Lung | Heat shock proteins | Activation | Urethane | Kinases | Nuclear transport | K-Ras protein | Proteins | RelB protein | Carcinogens | Inhibitors | Mice | Tumors | Cancer | Heat shock | urethane | NF-κB | non-oncogene addiction | CHUK | bioluminescence
Journal Article
Journal Article