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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2018, Volume 115, Issue 40, pp. 10076 - 10081
Chromosomal rearrangements, including translocations, are early and essential events in the formation of many tumors. Previous studies that defined the genetic... 
Nonhomologous end joining | PARP3 | Rearrangements | PATHWAYS | STRAND BREAK REPAIR | CLASS SWITCH RECOMBINATION | MULTIDISCIPLINARY SCIENCES | Parp3 | CHROMOSOMAL TRANSLOCATION FORMATION | nonhomologous end joining | DNA | rearrangements | LYMPHOMA | GENERATION | HOMOLOGOUS RECOMBINATION | AID | Oncogene Proteins, Fusion - metabolism | Poly (ADP-Ribose) Polymerase-1 - metabolism | DNA End-Joining Repair - physiology | Receptor Protein-Tyrosine Kinases - metabolism | Mouse Embryonic Stem Cells - metabolism | Poly(ADP-ribose) Polymerases - metabolism | Animals | Poly(ADP-ribose) Polymerases - genetics | Anaplastic Lymphoma Kinase | Receptor Protein-Tyrosine Kinases - genetics | Oncogene Proteins, Fusion - genetics | Immunoglobulin Class Switching - physiology | Mice | B-Lymphocytes - metabolism | Poly (ADP-Ribose) Polymerase-1 - genetics | Fibroblasts - metabolism | Genetic research | Enzymes | Genetic aspects | Research | Chromosomes | Recombination | DNA damage | Embryo cells | Stem cell transplantation | Chromosome rearrangements | ADP | Genotype & phenotype | Next-generation sequencing | Clonal deletion | Ribose | Fibroblasts | Deletion | Deoxyribonucleic acid--DNA | Translocation | Phenotypes | Inversions | Data processing | Polymerase chain reaction | Polymerase | Poly(ADP-ribose) Polymerase 1 | Chromosome translocations | Lymphocytes B | Stem cells | Non-homologous end joining | Tumors | Index Medicus | Biological Sciences
Journal Article
Journal Article
DNA Repair, ISSN 1568-7864, 2008, Volume 7, Issue 10, pp. 1765 - 1771
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2010, Volume 107, Issue 7, pp. 3034 - 3039
Class switch recombination (CSR) in β lymphocytes is initiated by introduction of multiple DNA double-strand breaks (DSBs) into switch (S) regions that flank... 
Beta cells | B lymphocytes | Exons | Genomics | DNA | Hybridomas | Genetic loci | AIDS | Mice | Chromosome translocation | Nonhomologous end-joining, switch region internal deletions | Class switch recombination | DNA double-strand repair | STRAND BREAK REPAIR | SOMATIC HYPERMUTATION | MULTIDISCIPLINARY SCIENCES | V(D)J RECOMBINATION | class switch recombination | REGION RECOMBINATION | MAMMALIAN-CELLS | B-CELLS | nonhomologous end-joining | switch region internal deletions | ERROR-PRONE | MU REGION | CLASS-SWITCH RECOMBINATION | DNA-REPAIR | Blotting, Southern | DNA Ligases - genetics | Immunoglobulin Class Switching - immunology | Molecular Sequence Data | In Situ Hybridization, Fluorescence | DNA Primers - genetics | DNA-Binding Proteins - genetics | DNA Breaks, Double-Stranded | Mice, Knockout | Animals | Antigens, Nuclear - genetics | B-Lymphocytes - immunology | Ku Autoantigen | Base Sequence | Genes, myc - genetics | DNA Ligase ATP | DNA Repair - immunology | Immunoglobulin Switch Region - genetics | Translocation, Genetic - immunology | Immunoglobulin Class Switching - genetics | Immunoglobulin Heavy Chains - genetics | Translocation, Genetic - genetics | Immunoglobulins | Translocation (Genetics) | Ligases | Chromosome deletion | Research | Properties | Observations | DNA repair | Lymphocytes | Chromosomes | Deoxyribonucleic acid--DNA | Cells | Index Medicus | Biological Sciences | nonhomologous end-joining, switch region internal deletions
Journal Article
Journal Article
Biochemistry and Cell Biology, ISSN 0829-8211, 2016, Volume 94, Issue 5, pp. 396 - 406
DNA double strand breaks (DSBs) are dangerous sources of genome instability and must be repaired by the cell. Nonhomologous end-joining (NHEJ) is an... 
hétérodimère Ku | jonction d’extrémités non homologues | réparation de bris double-brins | nonhomologous end-joining | DNA ligase IV | ADN ligase IV | Ku heterodimer | end-processing | double strand break repair | traitement des extrémités | Double strand break repair | End-processing | Nonhomologous end-joining
Journal Article