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gastroenterology & hepatology (4) 4
life sciences & biomedicine (4) 4
science & technology (4) 4
gastroenterology and hepatology (3) 3
humans (3) 3
udca, ursodeoxycholic acid (3) 3
ursodeoxycholic acid (3) 3
animals (2) 2
bile acids (2) 2
bile acids and salts - metabolism (2) 2
cholangitis (2) 2
cholestasis (2) 2
hepatology (2) 2
liver (2) 2
liver diseases (2) 2
norudca (2) 2
norudca, norursodeoxycholic acid (2) 2
norursodeoxycholic acid (2) 2
patients (2) 2
receptors, cytoplasmic and nuclear - metabolism (2) 2
ursodeoxycholic acid - analogs & derivatives (2) 2
ursodiol (2) 2
19, fibroblast growth factor 15 (1) 1
3 (1) 1
6-ecdca, 6-ethylchenodeoxycholic acid (1) 1
8, cholesterol efflux pump, atp-binding cassette, subfamily g, member 5 (1) 1
abcb4 (1) 1
abcb4/mdr2, canalicular phospholipid export pump/multidrug resistance protein 2 (1) 1
abcg5 (1) 1
abcg5/8, cholesterol efflux pump, atp-binding cassette, subfamily g, member 5/8 (1) 1
ae2, anion exchanger 2 (1) 1
alfacalcidol (1) 1
alkaline phosphatase (1) 1
allografts (1) 1
alt, alanine aminotransferase (1) 1
alt, aminotransferase (1) 1
ampk, amp activated protein kinase (1) 1
anova, analysis of variance (1) 1
anti-fibrotic therapy (1) 1
anti-inflammatory (1) 1
anti-inflammatory/anti-fibrotic therapy (1) 1
anti‐baff antibody (1) 1
ap, alkaline phosphatase (1) 1
ast, aspartate aminotransferase (1) 1
b. glabrata, biomphalaria glabrata (1) 1
ba, bile acid (1) 1
bcrp, breast cancer resistance protein, atp-binding cassette, subfamily g, member 2 (1) 1
beta (1) 1
bile acid receptor (1) 1
bile acid treatment (1) 1
bile acids and salts - therapeutic use (1) 1
bile acids, cholestasis, fatty liver disease, gallstones, liver regeneration, liver cancer (1) 1
bilirubin (1) 1
bmdc, bone marrow derived dendritic cells (1) 1
bmdm, bone marrow derived macrophages (1) 1
bric, benign recurrent intrahepatic cholestasis (1) 1
bsep, bile salt export pump (1) 1
calcifediol (1) 1
car, constitutive androstane receptor (1) 1
carrier proteins - metabolism (1) 1
cell survival (1) 1
cholagogues and choleretics - metabolism (1) 1
cholagogues and choleretics - pharmacology (1) 1
cholangitis, sclerosing (1) 1
cholestasis - metabolism (1) 1
clinical outcomes (1) 1
clinical trials (1) 1
corticoids (1) 1
corticosteroids (1) 1
deoxycholic acid (1) 1
disease models, animal (1) 1
drug monitoring (1) 1
drug resistance in microorganisms (1) 1
egfr, epidermal growth factor receptor (1) 1
endocrinology & metabolism (1) 1
epidermal growth factor (1) 1
etiology (1) 1
fatty liver disease (1) 1
fgf15 (1) 1
fgf15/19, fibroblast growth factor 15/19 (1) 1
fibroblast growth factors (1) 1
fibrosis (1) 1
fxr agonist (1) 1
fxr, farnesoid x receptor (1) 1
fxr, farnesoid x receptor/bile acid receptor (1) 1
gallbladder diseases (1) 1
gallstones (1) 1
glp-1, glucagon like peptide 1 (1) 1
glucagon (1) 1
gr, glucocorticoid receptor (1) 1
granuloma - drug therapy (1) 1
granuloma - immunology (1) 1
granuloma - pathology (1) 1
hcc, hepatocellular carcinoma (1) 1
hepatic granulomas (1) 1
hepatitis (1) 1
hnf1α, hepatocyte nuclear factor 1 alpha (1) 1
hnf4α, hepatocyte nuclear factor 4 alpha (1) 1
hp, hydroxyproline (1) 1
ibabp, intestinal bile acid-binding protein, fatty acid-binding protein 6 (1) 1
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1. Full Text Protective Effects of Norursodeoxycholic Acid Versus Ursodeoxycholic Acid on Thioacetamide-induced Rat Liver Fibrosis
by Buko, Vyacheslav U and Lukivskaya, Oxana Y and Naruta, Elena E and Belonovskaya, Elena B and Tauschel, Horst-Dietmar
Journal of clinical and experimental hepatology, ISSN 0973-6883, 2014, Volume 4, Issue 4, pp. 293 - 301
Endocrinology & Metabolism | Gastroenterology and Hepatology | thioacetamide | fibrosis | norursodeoxycholic acid | ursodeoxycholic acid | liver | Thioacetamide | Norursodeoxycholic acid | Liver | Fibrosis | Ursodeoxycholic acid | SEM, standard error of the mean | NorUDCA, norursodeoxycholic acid | TAA, thioacetamide | ANOVA, analysis of variance | UDCA, ursodeoxycholic acid | AST, aspartate aminotransferase | TIMP-1, tissue inhibitor of metalloproteinase-1 | Original | ALT, aminotransferase
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2. Full Text Bile acid transporters and regulatory nuclear receptors in the liver and beyond
by Halilbasic, Emina and Claudel, Thierry and Trauner, Michael
Journal of hepatology, ISSN 0168-8278, 2012, Volume 58, Issue 1, pp. 155 - 168
Gastroenterology and Hepatology | Gallstones | Liver cancer | Bile acids | Fatty liver disease | Cholestasis | Liver regeneration | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Animals | Carrier Proteins - metabolism | Cholestasis - metabolism | Membrane Glycoproteins - metabolism | Humans | Liver - metabolism | Bile Acids and Salts - metabolism | Liver Diseases - metabolism | Liver Regeneration - physiology | Receptors, Cytoplasmic and Nuclear - metabolism | Drug resistance in microorganisms | Corticosteroids | Glucagon | Calcifediol | Ursodiol | Deoxycholic acid | Epidermal growth factor | Vitamin D | Physiological aspects | Fibroblast growth factors | Alfacalcidol | Index Medicus | IBABP (FABP6, ILBP), intestinal bile acid-binding protein, fatty acid-binding protein 6 | PFIC, progressive familial intrahepatic cholestasis | TNFα, tumor necrosis factor α | 3 (human) | SRC2, p160 steroid receptor coactivator | NAFLD, non-alcoholic fatty liver disease | BA, bile acid | bile acid receptor | 8, cholesterol efflux pump, ATP-binding cassette, subfamily G, member 5 | UDCA, ursodeoxycholic acid | LRH-1 (NR5A2), liver receptor homolog-1 | LCA, lithocholic acid | LXRα (NR1H3), liver X receptor alpha | PPARγ (NR1C3), peroxisome proliferator-activated receptor gamma | OSTαβ, organic solute transporter alpha | ABCG5 | AMPK, AMP activated protein kinase | NASH, non-alcoholic steatohepatitis | SHP (NR0B2), short heterodimer partner | OATP1A2 (SLCO1A2, OATP1, OATP-A, SLC21A3), solute carrier organic anion transporter family, member 1A2 | EGFR, epidermal growth factor receptor | IL6, interleukin 6 | TGR5, G protein-coupled bile acid receptor | PH, partial hepatectomy | AE2, anion exchanger 2 | PSC, primary sclerosing cholangitis | OATP1B1 (SLCO1B1, OATP2, OATP-C, SLC21A6), solute carrier organic anion transporter family, member 1B1 | RARα (NR1B1), retinoic acid receptor alpha | GLP-1, glucagon like peptide 1 | VDR (NR1I1), vitamin D receptor. Please note that for the convenience of better readability and clarity, abbreviations for transporters and nuclear receptors were capitalized throughout this article when symbols were identical for human and rodents | MRP2 (ABCC2), multidrug resistance-associated protein 2, ATP-binding cassette, subfamily C, member 2 | NTCP (SLC10A1), sodium | CAR (NR1I3), constitutive androstane receptor | taurocholate cotransporting polypeptide, solute carrier family 10, member 1 | PPARα (NR1C1), peroxisome proliferator-activated receptor alpha | Review | GR (NR3C1), glucocorticoid receptor | Bile acids, Cholestasis, Fatty liver disease, Gallstones, Liver regeneration, Liver cancer | 19, fibroblast growth factor 15 | Mdr2 | ICP, intrahepatic cholestasis of pregnancy | BRIC, benign recurrent intrahepatic cholestasis | OATP1B3 (SLCO1B3, OATP8, SLC21A8), solute carrier organic anion transporter family, member 1B3 | MRP3 (ABCC3), multidrug resistance-associated protein 3, ATP-binding cassette, subfamily C, member 3 | beta | MDR1 (ABCB1), p-glycoprotein, ATP-binding cassette, subfamily B, member 1 | norUDCA, norursodeoxycholic acid | 6-ECDCA, 6-ethylchenodeoxycholic acid | FXR (NR1H4), farnesoid X receptor | BCRP (ABCG2), breast cancer resistance protein, ATP-binding cassette, subfamily G, member 2 | HNF4α (NR2A1), hepatocyte nuclear factor 4 alpha | PBC, primary biliary cirrhosis | MDR3 (ABCB4), multidrug resistance protein 2 (rodents) | HNF1α, hepatocyte nuclear factor 1 alpha | NR, nuclear receptor | FGF15 | RXRα (NR2B1), retinoid X receptor alpha | PXR (NR1I2), pregnane X receptor | BSEP (ABCB11), bile salt export pump | HCC, hepatocellular carcinoma | MRP4 (ABCC4), multidrug resistance-associated protein 4, ATP-binding cassette, subfamily C, member 4 | TPN, total parenteral nutrition
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3. Full Text Farnesoid X Receptor Agonists and Other Bile Acid Signaling Strategies for Treatment of Liver Disease
by Halilbasic, Emina and Fuchs, Claudia and Traussnigg, Stefan and Trauner, Michael
Digestive diseases (Basel), ISSN 0257-2753, 06/2016, Volume 34, Issue 5, pp. 580 - 588
Liver and Biliary System | Nuclear hormone receptor | Ursodeoxycholic acid (UDCA) | Norursodeoxycholic acid (norUDCA) | Obeticholic acid (OCA) | Transmembrane G protein-coupled receptor | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Liver Diseases - genetics | Liver Neoplasms - genetics | Receptors, G-Protein-Coupled - metabolism | Humans | Liver Neoplasms - drug therapy | Bile Acids and Salts - metabolism | Metabolic Diseases - drug therapy | Inflammation | Receptors, Cytoplasmic and Nuclear - agonists | Signal Transduction - genetics | Bile Acids and Salts - therapeutic use | Metabolic Diseases - genetics | Liver Diseases - drug therapy | Molecular Targeted Therapy - methods | Receptors, Cytoplasmic and Nuclear - metabolism | Index Medicus
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4. Full Text 24- nor -ursodeoxycholic acid ameliorates inflammatory response and liver fibrosis in a murine model of hepatic schistosomiasis
by Sombetzki, Martina and Fuchs, Claudia D and Fickert, Peter and Österreicher, Christoph H and Mueller, Michaela and Claudel, Thierry and Loebermann, Micha and Engelmann, Robby and Langner, Cord and Sahin, Emine and Schwinge, Dorothee and Guenther, Nina D and Schramm, Christoph and Mueller-Hilke, Brigitte and Reisinger, Emil C and Trauner, Michael
Journal of hepatology, ISSN 0168-8278, 2014, Volume 62, Issue 4, pp. 871 - 878
Gastroenterology and Hepatology | Schistosoma mansoni infection | Bile acids | Liver fibrosis | Anti-inflammatory/anti-fibrotic therapy | Hepatic granulomas | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Immunohistochemistry | Inflammation - pathology | Liver Cirrhosis - immunology | Cholagogues and Choleretics - pharmacology | Ursodeoxycholic Acid - analogs & derivatives | Schistosomiasis mansoni - immunology | Inflammation - drug therapy | T-Lymphocytes - drug effects | Disease Models, Animal | Schistosomiasis mansoni - physiopathology | Liver Cirrhosis - drug therapy | Liver Cirrhosis - etiology | Cholagogues and Choleretics - metabolism | Schistosomiasis mansoni - complications | Treatment Outcome | Inflammation - immunology | Granuloma - pathology | Ursodeoxycholic Acid - pharmacology | Animals | Lymphocyte Activation - drug effects | Liver Cirrhosis - pathology | Granuloma - drug therapy | Granuloma - immunology | T-Lymphocytes - immunology | Mice | Liver Cirrhosis - physiopathology | Schistosomiasis mansoni - pathology | Ursodeoxycholic Acid - metabolism | Drug Monitoring | Ursodiol | Liver diseases | Index Medicus | ALT, alanine aminotransferase | HP, hydroxyproline | Mdr2, canalicular phospholipid export pump | BMDC, bone marrow derived dendritic cells | BMDM, bone marrow derived macrophages | M-CSF, macrophage colony-stimulating factor | multidrug resistance protein 2 | norUDCA, 24-nor-ursodeoxycholic acid | anti-fibrotic therapy | Abcb4 | B. glabrata, Biomphalaria glabrata | UDCA, ursodeoxycholic acid | S. mansoni, Schistosoma mansoni | Anti-inflammatory | AP, alkaline phosphatase
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5. Full Text 24-Norursodeoxycholic acid in patients with primary sclerosing cholangitis: A new “urso saga” on the horizon?
by Chazouillères, Olivier
Journal of hepatology, ISSN 0168-8278, 09/2017, Volume 67, Issue 3, pp. 446 - 447
Bile acid treatment | PSC | UDCA | norUDCA | Cholestasis | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Cholangitis, Sclerosing | Ursodeoxycholic Acid - analogs & derivatives | Humans | Alkaline phosphatase | Inflammatory bowel diseases | Intestine | Medical treatment | Liver | Cholangitis | Gallbladder diseases | Bilirubin | Pruritus | Patients | Clinical outcomes | Placebo effect | Index Medicus
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6. Full Text Emerging novel treatments for autoimmune liver diseases
by Tanaka, Atsushi
Hepatology research, ISSN 1386-6346, 05/2019, Volume 49, Issue 5, pp. 489 - 499
FXR agonist | anti‐BAFF antibody | norUDCA | Corticoids | Liver diseases | Cell survival | Syngeneic grafts | Cholangitis | Clinical trials | Patients | Immunosuppressive agents | Ursodeoxycholic acid | Hepatitis | Allografts | Etiology | Liver transplantation
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